
Medical Center District Packages (Flight + Hotel)
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Where to stay in Medical Center District
Find the best Medical Center District areas and neighborhoods for the activities you enjoy most. Learn more about Medical Center District

Downtown San Antonio
4 out of top 10 points of interest in this area
4.5/5(42 area reviews)
Explore the network of pedestrian paths that follows the beautiful San Antonio River to discover restaurants and bars, gift shops, galleries and museums.
Top hotels in Medical Center District

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
4431 Horizon Hill Blvd, San Antonio, TX
Fully refundableReserve now, pay when you stay
The price is ฿2,852 per night from 5 Aug to 6 Aug
฿2,852
฿3,371 total
5 Aug - 6 Aug
includes taxes & fees
8.4/10 Very Good! (2,769 reviews)
"Reasonable price, clean, comfortable room. TV remote has not Guide and that was a bit irritating but no really important to the over all stay since rest was the object. Breakfast was good."
Reviewed on 21 Jul 2025

San Antonio Marriott Northwest Medical Center
3233 NW Loop 410, San Antonio, TX
Fully refundableReserve now, pay when you stay
The price is ฿2,804 per night from 7 Aug to 8 Aug
฿2,804
฿3,332 total
7 Aug - 8 Aug
includes taxes & fees
8.4/10 Very Good! (1,013 reviews)
"standard hotel but on top of service"
Reviewed on 14 Jul 2025

Fairfield Inn & Suites by Marriott San Antonio Medical Center
7203 Wurzbach Road, San Antonio, TX
Fully refundableReserve now, pay when you stay
The price is ฿2,958 per night from 3 Aug to 4 Aug
฿2,958
฿3,453 total
3 Aug - 4 Aug
includes taxes & fees
8.8/10 Excellent! (926 reviews)
Great Stay!
"I travel with my kids to San Antonio once or twice a year, and Fairfield Inn has become our go-to place to stay. I’m very picky when it comes to cleanliness. I notice even the smallest things like dust behind furniture. This hotel always gives me peace of mind. It’s extremely clean, which makes me ..."
Reviewed on 16 Jul 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Things to do

San Antonio: Discovery Tour at Natural Bridge Caverns
฿1,168
per adult
92% of travellers recommend

San Antonio: Tower of the Americas Entry Ticket
฿685
per adult
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.