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Our top choices for Medical Center District hotels

1. La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3.0 star property
Medical Center District
8.4 out of 10, Very good, (3,568 reviews)
"Clean room, staff was friendly"
United States
Vanessa
The price is ฿2,943
฿3,479 total
includes taxes & fees
15 Sept - 16 Sept
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

2. Fairfield Inn & Suites by Marriott San Antonio Medical Center

Fairfield Inn & Suites by Marriott San Antonio Medical Center
3.0 star property
Medical Center District
9.0 out of 10, Wonderful, (1,048 reviews)
"Great Stay!"
United States
Matthew
The price is ฿2,717
฿3,172 total
includes taxes & fees
11 Sept - 12 Sept
Fairfield Inn & Suites by Marriott San Antonio Medical Center

3. Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio
3.0 star property
Medical Center District
8.8 out of 10, Excellent, (1,002 reviews)
"Very clean facility, pool was in business a d it was nice, peaceful and quiet."
United States
Melissa
The price is ฿2,789
฿3,297 total
includes taxes & fees
29 Aug - 30 Aug
Courtyard by Marriott Medical Center San Antonio

4. San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center
3.5 star property
Medical Center District
8.6 out of 10, Excellent, (1,140 reviews)
"Great place to stay"
United States
Bradley
The price is ฿3,638
฿4,323 total
includes taxes & fees
21 Aug - 22 Aug
San Antonio Marriott Northwest Medical Center

5. Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
Medical Center District
9.2 out of 10, Wonderful, (1,407 reviews)
"Everything was excellent, food, clean room , drinks!!!!!"
United States
Diana
The price is ฿2,986
฿3,530 total
includes taxes & fees
19 Aug - 20 Aug
Drury Inn & Suites San Antonio Northwest Medical Center

6. Park Inn by Radisson, Medical Center

Park Inn by Radisson, Medical Center
2.0 star property
Medical Center District
7.2 out of 10, Good, (1,000 reviews)
"Room was very clean, walking distance from hospitals. Ample parking"
United States
Gloria
The price is ฿2,115
฿2,470 total
includes taxes & fees
8 Sept - 9 Sept
Park Inn by Radisson, Medical Center

7. Atria Inn & Suites

Atria Inn & Suites
2.0 star property
Medical Center District
7.4 out of 10, Good, (309 reviews)
"👌"
United States
Gloria
The price is ฿2,018
฿2,356 total
includes taxes & fees
16 Aug - 17 Aug
Atria Inn & Suites

8. Motel 6 San Antonio, TX - Northwest Medical Center

Motel 6 San Antonio, TX - Northwest Medical Center
2.0 star property
Medical Center District
6.0 out of 10, (999 reviews)
"front desk reps very friendly and helpful"
United States
Rachel
The price is ฿1,561
฿1,978 total
includes taxes & fees
16 Aug - 17 Aug
Motel 6 San Antonio, TX - Northwest Medical Center

9. OYO Inn & Suites Medical Center San Antonio

OYO Inn & Suites Medical Center San Antonio
2.0 star property
Medical Center District
7.4 out of 10, Good, (245 reviews)
"It was quiet and clean and the staff was very friendly"
United States
Ronnie
The price is ฿1,858
฿2,355 total
includes taxes & fees
28 Aug - 29 Aug
OYO Inn & Suites Medical Center San Antonio

10. Studio 6 San Antonio, Tx - Northwest Medical Center

Studio 6 San Antonio, Tx - Northwest Medical Center
2.0 star property
Medical Center District
7.4 out of 10, Good, (346 reviews)
"Good staff great room for the price Quiet area"
United States
RUDY AGUIRRE
The price is ฿1,556
฿1,817 total
includes taxes & fees
24 Aug - 25 Aug
Studio 6 San Antonio, Tx - Northwest Medical Center

11. Studio 6 Extended Stay - San Antonio, TX - Medical Center

Studio 6 Extended Stay - San Antonio, TX - Medical Center
2.0 star property
Medical Center District
6.8 out of 10, (974 reviews)
"Friendly staff, room was cleaned and well kept."
United States
Jose
The price is ฿1,723
฿2,103 total
includes taxes & fees
25 Aug - 26 Aug
Studio 6 Extended Stay - San Antonio, TX - Medical Center

12. Flex Studios

Flex Studios
2.5 star property
Medical Center District
6.2 out of 10, (563 reviews)
"Yes I would stay again"
United States
Jasper
The price is ฿1,314
฿1,553 total
includes taxes & fees
16 Aug - 17 Aug
Flex Studios

13. Hyatt Place San Antonio-Northwest/Medical Center

Hyatt Place San Antonio-Northwest/Medical Center
3.0 star property
3.7 km from Medical Center District
8.4 out of 10, Very good, (1,010 reviews)
"Clean, great staff and great location."
United States
Diana G
The price is ฿3,082
฿3,684 total
includes taxes & fees
15 Sept - 16 Sept
Hyatt Place San Antonio-Northwest/Medical Center

14. Drury Inn & Suites Near La Cantera Parkway

Drury Inn & Suites Near La Cantera Parkway
3.0 star property
La Cantera District, 9.5 km from Medical Center District
9.4 out of 10, Exceptional, (1,893 reviews)
"Love staying here !"
United States
Samantha
The price is ฿3,115
฿3,682 total
includes taxes & fees
6 Sept - 7 Sept
Drury Inn & Suites Near La Cantera Parkway

15. Holiday Inn Express San Antonio-Airport by IHG

Holiday Inn Express San Antonio-Airport by IHG
2.5 star property
8.9 km from Medical Center District
9.4 out of 10, Exceptional, (1,002 reviews)
"Excellent hotel, clean, great breakfast and amenities."
United States
Edgar
The price is ฿3,252
฿3,844 total
includes taxes & fees
13 Sept - 14 Sept
Holiday Inn Express San Antonio-Airport by IHG

16. Hampton Inn & Suites San Antonio Northwest/Medical Center

Hampton Inn & Suites San Antonio Northwest/Medical Center
2.5 star property
Northwest Side, 4.7 km from Medical Center District
8.4 out of 10, Very good, (1,046 reviews)
"Solid property… friendly staff, and great for an overnight business trip"
United States
James
The price is ฿2,966
฿3,572 total
includes taxes & fees
23 Aug - 24 Aug
Hampton Inn & Suites San Antonio Northwest/Medical Center

17. La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB

La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB
3.0 star property
9 km from Medical Center District
9.2 out of 10, Wonderful, (1,177 reviews)
"The staff was very helpful and it was close to everything we planned on going to"
United States
Ruben
The price is ฿3,255
฿3,801 total
includes taxes & fees
23 Aug - 24 Aug
La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB

18. Estancia del Norte San Antonio, Tapestry Collection by Hilton

Estancia del Norte San Antonio, Tapestry Collection by Hilton
3.5 star property
8.5 km from Medical Center District
9.0 out of 10, Wonderful, (1,003 reviews)
"I had a great stay! I highly recommend this hotel for a great stay!"
United States
Martha
The price is ฿4,593
฿5,429 total
includes taxes & fees
22 Aug - 23 Aug
Estancia del Norte San Antonio, Tapestry Collection by Hilton

19. Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

Heritage Inn & Suites San Antonio Airport, Trademark Wyndham
2.5 star property
Uptown, 9.3 km from Medical Center District
9.0 out of 10, Wonderful, (2,083 reviews)
"Nice clean hotel. Perfect for a stay near the airport with a shuttle to get you there!"
United States
George
The price is ฿2,651
฿3,134 total
includes taxes & fees
15 Sept - 16 Sept
Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

20. La Quinta Inn & Suites By Wyndham San Antonio At The Rim

La Quinta Inn & Suites By Wyndham San Antonio At The Rim
3.0 star property
11.9 km from Medical Center District
9.2 out of 10, Wonderful, (1,320 reviews)
"Great place to stay with family. Restaurants and shopping walking distance . I would stay here again ."
United States
Claudia
The price is ฿2,709
฿3,164 total
includes taxes & fees
15 Sept - 16 Sept
La Quinta Inn & Suites By Wyndham San Antonio At The Rim
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Medical Center District

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Lobby
Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
9.2
Wonderful
1,407 reviews
View
Lobby
Fairfield Inn & Suites by Marriott San Antonio Medical Center
3.0 star property
9.0
Wonderful
1,048 reviews
View
Bar (on property)
Courtyard by Marriott Medical Center San Antonio
3.0 star property
8.8
Excellent
1,002 reviews
View
Lobby
San Antonio Marriott Northwest Medical Center
3.5 star property
8.6
Excellent
1,140 reviews
View
Free daily buffet breakfast
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3.0 star property
8.4
Very good
3,568 reviews
View

Where to stay in Medical Center District

Find the best Medical Center District areas for the activities you enjoy most.

Downtown San Antonio

Explore the network of pedestrian paths that follows the beautiful San Antonio River to discover restaurants and bars, gift shops, galleries and museums.

Uptown

If you're spending some time in Uptown, Alamo Quarry Market and San Antonio Zoo and Aquarium are top sights worth seeing.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Northwest Side

If you're spending some time in Northwest Side, Huebner Oaks and Crystal Ice Palace are top sights worth seeing.

La Cantera District

If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

Top Medical Center District Hotel Reviews

Frequently asked questions

What is Medical Center District like?
Travellers are sure to enjoy a stay in San Antonio's Medical Center District neighbourhood. Are you looking for Medical Center District travel tips? Make sure that you visit USAA Corporate Office Headquarters and Cinemark San Antonio 16 while you're in the neighbourhood.
What's a favourite hotel to stay in Medical Center District?
Based on our traveller data, La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW is one of the top choices for your stay in Medical Center District. This hotel offers free breakfast and an outdoor pool. Other good options for your stay in the area include Courtyard by Marriott Medical Center San Antonio and Drury Inn & Suites San Antonio Northwest Medical Center.
How many hotels will I be able to find in Medical Center District?
Expedia has 131 hotels and other accommodation options in Medical Center District to choose from, making this an ideal home base for exploring the greater San Antonio area.
If I need to cancel my hotel reservation in Medical Center District, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within a 24-hour period of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to review the top deals on offer in Medical Center District.
What can I see and do in this San Antonio neighbourhood?
A few attractions you might want to check out while you're in Medical Center District are USAA Corporate Office Headquarters and Cinemark San Antonio 16. Wonderland of the Americas Mall and Regal Huebner Oaks are also worth a visit when you're out sightseeing in San Antonio.