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Our top choices for Medical Center District hotels

Fairfield Inn & Suites by Marriott San Antonio Medical Center

Fairfield Inn & Suites by Marriott San Antonio Medical Center
3.0 star property
Medical Center District
9.0 out of 10, Wonderful, (1,003 reviews)
"Very comfortable, everything was clean, great staff and it’s near all the important hospitals. "
United States
Jesus
The price is ฿2,333
฿2,723 total
includes taxes & fees
1 Mar - 2 Mar
Fairfield Inn & Suites by Marriott San Antonio Medical Center

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3.0 star property
Medical Center District
8.4 out of 10, Very good, (3,202 reviews)
"Great stay with nice breakfast and clean rooms "
United States
Leah
The price is ฿2,769
฿3,273 total
includes taxes & fees
22 Feb - 23 Feb
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio
3.0 star property
Medical Center District
8.8 out of 10, Excellent, (1,002 reviews)
"Clean rooms @ friendly staff!"
United States
LaTishe
The price is ฿2,775
฿3,281 total
includes taxes & fees
28 Feb - 1 Mar
Courtyard by Marriott Medical Center San Antonio

San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center
3.5 star property
Medical Center District
8.6 out of 10, Excellent, (1,013 reviews)
"Courteous staff, clean room, safe location "
United States
Danica
The price is ฿3,154
฿3,748 total
includes taxes & fees
28 Feb - 1 Mar
San Antonio Marriott Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
Medical Center District
9.2 out of 10, Wonderful, (1,279 reviews)
"Excellent awesome place we love it Room was super clean staff super nice "
United States
Maria
The price is ฿2,806
฿3,317 total
includes taxes & fees
3 Mar - 4 Mar
Drury Inn & Suites San Antonio Northwest Medical Center

Atria Inn & Suites

Atria Inn & Suites
2.0 star property
Medical Center District
7.4 out of 10, Good, (283 reviews)
"Room was good standings, staff was friendly "
United States
Luis
Atria Inn & Suites

Country Inn & Suites by Radisson, San Antonio Medical Center, TX

Country Inn & Suites by Radisson, San Antonio Medical Center, TX
3.0 star property
Medical Center District
6.8 out of 10, (1,001 reviews)
"Great place , front desk are helpful and friendly. Safe place to stay ."
United States
Justin
The price is ฿1,894
฿2,211 total
includes taxes & fees
22 Mar - 23 Mar
Country Inn & Suites by Radisson, San Antonio Medical Center, TX

Studio 6 San Antonio, Tx - Northwest Medical Center

Studio 6 San Antonio, Tx - Northwest Medical Center
2.0 star property
Medical Center District
7.4 out of 10, Good, (247 reviews)
"Good stay and safe area"
United States
Mario
The price is ฿1,578
฿1,842 total
includes taxes & fees
23 Feb - 24 Feb
Studio 6 San Antonio, Tx - Northwest Medical Center

Studio 6 San Antonio, TX - Medical Center

Studio 6 San Antonio, TX - Medical Center
2.0 star property
Medical Center District
6.8 out of 10, (828 reviews)
"Staff was great, very clean rooom"
United States
Laura
The price is ฿1,590
฿1,942 total
includes taxes & fees
21 Feb - 22 Feb
Studio 6 San Antonio, TX - Medical Center

Park Inn by Radisson

Park Inn by Radisson
2.0 star property
Medical Center District
7.2 out of 10, Good, (1,001 reviews)
"Room was spotless and bed was great."
United States
Pamela
The price is ฿1,992
฿2,326 total
includes taxes & fees
22 Mar - 23 Mar
Park Inn by Radisson

OYO Inn & Suites Medical Center San Antonio

OYO Inn & Suites Medical Center San Antonio
2.0 star property
Medical Center District
7.2 out of 10, Good, (228 reviews)
"Staff was courteous and professional and the room is nice."
United States
Thomas
The price is ฿1,982
฿2,532 total
includes taxes & fees
21 Feb - 22 Feb
OYO Inn & Suites Medical Center San Antonio

Motel 6 San Antonio, TX - Northwest Medical Center

Motel 6 San Antonio, TX - Northwest Medical Center
2.0 star property
Medical Center District
6.0 out of 10, (1,000 reviews)
"Great experience "
United States
John
The price is ฿1,629
฿1,926 total
includes taxes & fees
22 Feb - 23 Feb
Motel 6 San Antonio, TX - Northwest Medical Center

Flex Studios

Flex Studios
2.5 star property
Medical Center District
6.0 out of 10, (508 reviews)
"Was good, but there is no one overnight, security doesn't answer and the opening person was almost an hour late. "
United States
Michelle
The price is ฿1,356
฿1,602 total
includes taxes & fees
22 Feb - 23 Feb
Flex Studios

La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB

La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB
3.0 star property
9 km from Medical Center District
9.2 out of 10, Wonderful, (1,151 reviews)
"It was a great stay."
United States
Bridget
The price is ฿2,582
฿3,015 total
includes taxes & fees
1 Mar - 2 Mar
La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB

Hyatt Vacation Club at Wild Oak Ranch, San Antonio

Hyatt Vacation Club at Wild Oak Ranch, San Antonio
3.5 star property
Far West Side, 11.3 km from Medical Center District
9.0 out of 10, Wonderful, (1,458 reviews)
"Great Stay"
United States
Melissa
The price is ฿2,919
฿4,739 total
includes taxes & fees
23 Feb - 24 Feb
Hyatt Vacation Club at Wild Oak Ranch, San Antonio

Courtyard by Marriott San Antonio SeaWorld - Westover Hills

Courtyard by Marriott San Antonio SeaWorld - Westover Hills
3.0 star property
Far West Side, 12.1 km from Medical Center District
8.6 out of 10, Excellent, (1,135 reviews)
"the room was very clean and the staff was very friendly. Its was convenient to Seaworld and shopping destinations."
United States
Evelyn
The price is ฿3,154
฿3,748 total
includes taxes & fees
23 Feb - 24 Feb
Courtyard by Marriott San Antonio SeaWorld - Westover Hills

Hilton San Antonio Hill Country

Hilton San Antonio Hill Country
4.0 star property
Far West Side, 11.6 km from Medical Center District
8.6 out of 10, Excellent, (1,066 reviews)
"The room was very clean, room service was great. Perfect staycation."
United States
Christie
The price is ฿2,809
฿4,552 total
includes taxes & fees
1 Mar - 2 Mar
Hilton San Antonio Hill Country

Best Western near Lackland AFB/SeaWorld

Best Western near Lackland AFB/SeaWorld
2.5 star property
Far West Side, 6.9 km from Medical Center District
8.0 out of 10, Very good, (1,201 reviews)
"Great place to stay"
United States
Kala
The price is ฿1,746
฿2,039 total
includes taxes & fees
22 Feb - 23 Feb
Best Western near Lackland AFB/SeaWorld

Comfort Suites San Antonio Near Seaworld

Comfort Suites San Antonio Near Seaworld
2.5 star property
7 km from Medical Center District
7.8 out of 10, Good, (1,000 reviews)
"Great hotel for family stay."
United States
Luis
The price is ฿2,281
฿2,663 total
includes taxes & fees
8 Mar - 9 Mar
Comfort Suites San Antonio Near Seaworld

Holiday Inn Express & Suites San Antonio - Brooks City Base by IHG

Holiday Inn Express & Suites San Antonio - Brooks City Base by IHG
2.5 star property
22.7 km from Medical Center District
8.6 out of 10, Excellent, (873 reviews)
"Great rooms nice location "
United States
Eva
The price is ฿2,975
฿3,473 total
includes taxes & fees
1 Mar - 2 Mar
Holiday Inn Express & Suites San Antonio - Brooks City Base by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Medical Center District

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Lobby
Fairfield Inn & Suites by Marriott San Antonio Medical Center
3.0 star property
9.0
Wonderful
1,003 reviews
View
Lobby
Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
9.2
Wonderful
1,279 reviews
View
Lobby
San Antonio Marriott Northwest Medical Center
3.5 star property
8.6
Excellent
1,013 reviews
View
Bar (on property)
Courtyard by Marriott Medical Center San Antonio
3.0 star property
8.8
Excellent
1,002 reviews
View
Free daily buffet breakfast
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3.0 star property
8.4
Very good
3,202 reviews
View

Where to stay in Medical Center District

Find the best Medical Center District areas for the activities you enjoy most.

Downtown San Antonio

Explore the network of pedestrian paths that follows the beautiful San Antonio River to discover restaurants and bars, gift shops, galleries and museums.

Uptown

If you're spending some time in Uptown, San Antonio Zoo and Aquarium and Marion Koogler McNay Art Museum are top sights worth seeing.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Fort Sam Houston

You'll love the stunning river views in Fort Sam Houston, and you might want to stick around to check out United States Army Medical Department Museum, a top place to visit.

Arena District

If you're spending some time in Arena District, Frost Bank Center and Freeman Coliseum are top sights worth seeing.

Top Medical Center District Hotel Reviews

Frequently asked questions

What is Medical Center District like?
Travellers are sure to enjoy a stay in San Antonio's Medical Center District neighbourhood. Are you looking for Medical Center District travel tips? Make sure that you visit USAA Corporate Office Headquarters and Cinemark San Antonio 16 while you're in the neighbourhood.
What's a favourite hotel to stay in Medical Center District?
Based on Expedia customer reviews, Drury Inn & Suites San Antonio Northwest Medical Center is the highest ranked property in Medical Center District. This hotel offers free breakfast and an indoor pool. Other favourite options in the area include Fairfield Inn & Suites by Marriott San Antonio Medical Center and Courtyard by Marriott Medical Center San Antonio.
How many hotels will I be able to find in Medical Center District?
Expedia has 120 hotels and other accommodation options in Medical Center District to choose from, making this an ideal home base for exploring the greater San Antonio area.
If I need to cancel my hotel reservation in Medical Center District, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within a 24-hour period of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to review the top deals on offer in Medical Center District.
What can I see and do in this San Antonio neighbourhood?
USAA Corporate Office Headquarters, Cinemark San Antonio 16 and The San Antonio Art Institute are just a few attractions to check out in Medical Center District. Wonderland of the Americas Mall and Regal Huebner Oaks are also worth a visit when you're out sightseeing in San Antonio.