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Our top choices for Medical Center District hotels

1. La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3.0 star property
Medical Center District
8.4 out of 10, Very good, (3,535 reviews)
"Loved our stay also loved breakfast"
United States
Marlene
The price is ฿2,981
฿3,524 total
includes taxes & fees
5 Aug - 6 Aug
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

2. Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio
3.0 star property
Medical Center District
8.8 out of 10, Excellent, (1,001 reviews)
"Very clean facility, pool was in business a d it was nice, peaceful and quiet."
United States
Melissa
The price is ฿2,994
฿3,539 total
includes taxes & fees
14 Aug - 15 Aug
Courtyard by Marriott Medical Center San Antonio

3. Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
Medical Center District
9.2 out of 10, Wonderful, (1,409 reviews)
"It was amazing everything was perfect!!"
United States
Chad
The price is ฿3,027
฿3,578 total
includes taxes & fees
16 Aug - 17 Aug
Drury Inn & Suites San Antonio Northwest Medical Center

4. Fairfield Inn & Suites by Marriott San Antonio Medical Center

Fairfield Inn & Suites by Marriott San Antonio Medical Center
3.0 star property
Medical Center District
9.0 out of 10, Wonderful, (1,043 reviews)
"Great place"
United States
Yosvany
The price is ฿2,909
฿3,396 total
includes taxes & fees
2 Aug - 3 Aug
Fairfield Inn & Suites by Marriott San Antonio Medical Center

5. San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center
3.5 star property
Medical Center District
8.6 out of 10, Excellent, (1,137 reviews)
"Great place to stay"
United States
Bradley
The price is ฿3,688
฿4,383 total
includes taxes & fees
8 Aug - 9 Aug
San Antonio Marriott Northwest Medical Center

6. Park Inn by Radisson

Park Inn by Radisson
2.0 star property
Medical Center District
7.4 out of 10, Good, (1,003 reviews)
"Room was very clean, walking distance from hospitals. Ample parking"
United States
Gloria
The price is ฿2,173
฿2,537 total
includes taxes & fees
18 Aug - 19 Aug
Park Inn by Radisson

7. OYO Inn & Suites Medical Center San Antonio

OYO Inn & Suites Medical Center San Antonio
2.0 star property
Medical Center District
7.4 out of 10, Good, (244 reviews)
"It was quiet and clean and the staff was very friendly"
United States
Ronnie
The price is ฿1,884
฿2,387 total
includes taxes & fees
14 Aug - 15 Aug
OYO Inn & Suites Medical Center San Antonio

8. Studio 6 San Antonio, Tx - Northwest Medical Center

Studio 6 San Antonio, Tx - Northwest Medical Center
2.0 star property
Medical Center District
7.4 out of 10, Good, (336 reviews)
"Good staff great room for the price Quiet area"
United States
RUDY AGUIRRE
The price is ฿1,578
฿1,842 total
includes taxes & fees
2 Aug - 3 Aug
Studio 6 San Antonio, Tx - Northwest Medical Center

9. Motel 6 San Antonio, TX - Northwest Medical Center

Motel 6 San Antonio, TX - Northwest Medical Center
2.0 star property
Medical Center District
6.0 out of 10, (1,005 reviews)
"Everyone In that hotels Is pretty friendly and great service."
United States
José
The price is ฿1,597
฿2,023 total
includes taxes & fees
30 Jul - 31 Jul
Motel 6 San Antonio, TX - Northwest Medical Center

10. Atria Inn & Suites

Atria Inn & Suites
2.0 star property
Medical Center District
7.4 out of 10, Good, (306 reviews)
The price is ฿2,331
฿2,721 total
includes taxes & fees
29 Jul - 30 Jul
Atria Inn & Suites

11. Studio 6 Extended Stay - San Antonio, TX - Medical Center

Studio 6 Extended Stay - San Antonio, TX - Medical Center
2.0 star property
Medical Center District
6.8 out of 10, (956 reviews)
"Friendly staff, room was cleaned and well kept."
United States
Jose
The price is ฿1,749
฿2,134 total
includes taxes & fees
29 Jul - 30 Jul
Studio 6 Extended Stay - San Antonio, TX - Medical Center

12. Flex Studios

Flex Studios
2.5 star property
Medical Center District
6.2 out of 10, (556 reviews)
"Yes I would stay again"
United States
Jasper
The price is ฿1,332
฿1,574 total
includes taxes & fees
29 Jul - 30 Jul
Flex Studios

13. Hyatt Place San Antonio-Northwest/Medical Center

Hyatt Place San Antonio-Northwest/Medical Center
3.0 star property
3.7 km from Medical Center District
8.4 out of 10, Very good, (1,021 reviews)
"Clean, great staff and great location."
United States
Diana G
The price is ฿3,128
฿3,739 total
includes taxes & fees
4 Aug - 5 Aug
Hyatt Place San Antonio-Northwest/Medical Center

14. Hampton Inn & Suites San Antonio Northwest/Medical Center

Hampton Inn & Suites San Antonio Northwest/Medical Center
2.5 star property
Northwest Side, 4.7 km from Medical Center District
8.4 out of 10, Very good, (1,056 reviews)
"We love a clean bedding/bathroom/room and all that was perfect also nice helpful staff"
United States
Yolanda
The price is ฿2,868
฿3,455 total
includes taxes & fees
23 Aug - 24 Aug
Hampton Inn & Suites San Antonio Northwest/Medical Center

15. Drury Plaza Hotel San Antonio Airport

Drury Plaza Hotel San Antonio Airport
3.0 star property
9 km from Medical Center District
9.4 out of 10, Exceptional, (2,215 reviews)
"The hotel was great, highly recommend! "
United States
Dianne
The price is ฿3,296
฿3,896 total
includes taxes & fees
23 Aug - 24 Aug
Drury Plaza Hotel San Antonio Airport

16. Holiday Inn Express San Antonio-Airport by IHG

Holiday Inn Express San Antonio-Airport by IHG
2.5 star property
8.9 km from Medical Center District
9.4 out of 10, Exceptional, (1,016 reviews)
"Excellent hotel, clean, great breakfast and amenities."
United States
Edgar
The price is ฿2,982
฿3,525 total
includes taxes & fees
9 Aug - 10 Aug
Holiday Inn Express San Antonio-Airport by IHG

17. La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB

La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB
3.0 star property
9 km from Medical Center District
9.2 out of 10, Wonderful, (1,192 reviews)
"The property was quiet, clean, and well-maintained even during the busy summer months of visiting Sea World. I would definitely recommend based on its convenient location and value."
United States
Leonard
The price is ฿3,511
฿4,100 total
includes taxes & fees
27 Aug - 28 Aug
La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB

18. Aloft by Marriott San Antonio UTSA Area

Aloft by Marriott San Antonio UTSA Area
3.0 star property
Northwest Side, 7.8 km from Medical Center District
9.0 out of 10, Wonderful, (1,018 reviews)
"Love the place"
United States
Sylvia
The price is ฿3,282
฿3,880 total
includes taxes & fees
6 Aug - 7 Aug
Aloft by Marriott San Antonio UTSA Area

19. Comfort Inn and Suites Near Medical Center

Comfort Inn and Suites Near Medical Center
2.5 star property
4.6 km from Medical Center District
7.2 out of 10, Good, (2,186 reviews)
"Great hotel,great staff"
United States
Masumbuko
The price is ฿1,880
฿2,329 total
includes taxes & fees
9 Aug - 10 Aug
Comfort Inn and Suites Near Medical Center

20. Estancia del Norte San Antonio, Tapestry Collection by Hilton

Estancia del Norte San Antonio, Tapestry Collection by Hilton
3.5 star property
8.5 km from Medical Center District
8.8 out of 10, Excellent, (1,000 reviews)
"Beautiful hotel , great restaurant on site. The rooms were nice and clean, and the staff was very friendly."
United States
Cj
The price is ฿4,832
฿5,711 total
includes taxes & fees
4 Aug - 5 Aug
Estancia del Norte San Antonio, Tapestry Collection by Hilton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Medical Center District

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Lobby
Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
9.2
Wonderful
1,409 reviews
View
Lobby lounge
Fairfield Inn & Suites by Marriott San Antonio Medical Center
3.0 star property
9.0
Wonderful
1,043 reviews
View
Bar (on property)
Courtyard by Marriott Medical Center San Antonio
3.0 star property
8.8
Excellent
1,001 reviews
View
Lobby
San Antonio Marriott Northwest Medical Center
3.5 star property
8.6
Excellent
1,137 reviews
View
Free daily buffet breakfast
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3.0 star property
8.4
Very good
3,535 reviews
View

Where to stay in Medical Center District

Find the best Medical Center District areas for the activities you enjoy most.

Downtown San Antonio

Explore the network of pedestrian paths that follows the beautiful San Antonio River to discover restaurants and bars, gift shops, galleries and museums.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Uptown

If you're spending some time in Uptown, San Antonio Zoo and Aquarium and Marion Koogler McNay Art Museum are top sights worth seeing.

La Cantera District

If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

Midtown

Unique features of Midtown include the river views and bars. Make a stop by San Antonio Zoo and Aquarium or Historic Brackenridge Golf Course while you're exploring the area.

Top Medical Center District Hotel Reviews

Frequently asked questions

What is Medical Center District like?
Travellers are sure to enjoy a stay in San Antonio's Medical Center District neighbourhood. Are you looking for Medical Center District travel tips? Make sure that you visit USAA Corporate Office Headquarters and The San Antonio Art Institute while you're in the neighbourhood.
What's a favourite hotel to stay in Medical Center District?
Based on our traveller data, La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW is one of the top choices for your stay in Medical Center District. This hotel offers free breakfast and an outdoor pool. Other good options for your stay in the area include Courtyard by Marriott Medical Center San Antonio and Drury Inn & Suites San Antonio Northwest Medical Center.
How many hotels will I be able to find in Medical Center District?
Expedia has 130 hotels and other accommodation options in Medical Center District to choose from, making this an ideal home base for exploring the greater San Antonio area.
If I need to cancel my hotel reservation in Medical Center District, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within a 24-hour period of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to review the top deals on offer in Medical Center District.
What can I see and do in this San Antonio neighbourhood?
USAA Corporate Office Headquarters, The San Antonio Art Institute and Cinemark San Antonio 16 are just a few attractions to check out in Medical Center District. Wonderland of the Americas Mall and Regal Huebner Oaks are also worth a visit when you're out sightseeing in San Antonio.