The Best Hotels Closest to El Machetazo Santa Ana in Panama City - 2026 Updated Prices

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Our top choices for El Machetazo Santa Ana hotels

A spacious indoor courtyard with tiled flooring, multiple seating areas, and hanging plants.

A room with a large window, a television mounted on the wall, and two chairs.

A living room with a sofa, a coffee table with books, a chandelier, and a kitchen with wooden cabinets and granite countertops.

An open door revealing a balcony with a wrought iron railing, potted plants, and a window with a curtain.

1. La Isabela Suites

San Felipe, 0.3 km from El Machetazo Santa Ana

David

฿5,217

฿5,738 total

includes taxes & fees

26 Sept - 27 Sept

A multi-story building with ornate balconies, large windows, and decorative moldings.

A spacious restaurant with high wooden ceilings, multiple tables and chairs, and a bar area with shelves of bottles and glasses.

A spacious hotel room with a large bed, a seating area with a sofa and chairs, a dining table, and a staircase.

A room with a white sofa, a wooden chair, a mirror, and a large window with curtains.

2. Hotel Plaza Herrera

San Felipe, 0.4 km from El Machetazo Santa Ana

Christina

฿6,775

฿7,452 total

includes taxes & fees

24 Sept - 25 Sept

A balcony with a table, chairs, and a view of a city skyline across a body of water.

A spacious lobby with high ceilings, modern furniture, and decorative lighting fixtures.

A spacious living room with a high ceiling, large windows, and a decorative ceiling fan.

A spacious lobby with a round coffee table, seating areas, and a large wall clock.

3. Sofitel Legend Casco Viejo, Panama City

San Felipe, 0.8 km from El Machetazo Santa Ana

Jose

฿11,816

฿12,998 total

includes taxes & fees

6 Oct - 7 Oct

A grand, illuminated building with a symmetrical facade, multiple balconies, and a prominent entrance.

A spacious bedroom with a large bed, a chandelier, a bathroom with a bathtub, and a dining area.

A glass of white wine on a balcony railing overlooking a city street with buildings and cars.

A kitchen with a glass-top table, a coffee machine, wine glasses, and a bottle of wine.

4. La Concordia Boutique Hotel

San Felipe, 0.2 km from El Machetazo Santa Ana

Jadah

฿6,675

฿7,343 total

includes taxes & fees

18 Oct - 19 Oct

A spacious outdoor patio with wicker furniture, potted plants, and umbrellas providing shade.

A dimly lit restaurant with wooden decor, tables, and chairs arranged for dining.

A modern hotel lobby with beige sofas, marble flooring, and a reception desk.

A hotel with a covered entrance, multiple windows, and a balcony with plants.

5. Hotel San Felipe

San Felipe, 0.4 km from El Machetazo Santa Ana

Rebecca

฿4,306

฿4,736 total

includes taxes & fees

28 Sept - 29 Sept

A modern interior with a spiral staircase, hardwood flooring, a white armchair, and decorative wall art.

A rooftop deck with outdoor seating, a hot tub, and a view of a historic building with a tiled roof.

A bedroom with a large bed, wooden paneling, a desk, and a chair.

A modern living room with a sofa, coffee table, and chairs. There is a dining area with a table and chairs. The room has large windows with sheer curtains.

6. Casa Mallet by Wynwood House

San Felipe, 0.6 km from El Machetazo Santa Ana

Lauren

฿7,854

฿9,554 total

includes taxes & fees

7 Oct - 8 Oct

A restaurant interior with checkered flooring, wooden tables, wicker chairs, and hanging wicker lamps.

An outdoor patio with a checkered floor, a bar area with cushioned seating, and a large umbrella providing shade.

A multi-level interior with a checkered floor, wooden railings, and potted plants.

A rooftop terrace with a hot tub, wooden deck, outdoor seating, and a view of a cityscape including a clock tower.

7. Amarla Boutique Hotel Casco Viejo Adults Only

San Felipe, 0.6 km from El Machetazo Santa Ana

Shanae

฿7,852

฿8,638 total

includes taxes & fees

24 Sept - 25 Sept

A spacious living area with a modern sofa, a wooden coffee table, and a staircase leading to an upper level.

A bedroom with a large bed, a ceiling fan, and multiple windows.

A spacious living area with a large TV, a stone accent wall, and a modern kitchen in the background.

A spiral staircase with a stone wall and a view of a living area with a fireplace.

8. Casa Lefevre By Wynwood House

San Felipe, 0.5 km from El Machetazo Santa Ana

Selam

฿4,209

฿5,544 total

includes taxes & fees

27 Sept - 28 Sept

A spacious indoor area with high ceilings, large windows, and multiple dining tables.

A restaurant with brick walls, arched windows, and a variety of seating arrangements including tables and chairs.

A spacious lobby with a tiled floor, large windows, and potted plants.

A multi-story hotel with a central courtyard, balconies, and a view of the city skyline.

9. American Trade Hotel

San Felipe, 0.4 km from El Machetazo Santa Ana

James

฿6,729

฿7,401 total

includes taxes & fees

4 Oct - 5 Oct

A multi-story building with balconies, large windows, and a clear blue sky.

A hotel room with a brick wall, a large window with curtains, a bed with pillows, a nightstand, and a chair.

A hallway with a brick wall, a blue door, and a chair with a cushion.

A living room with a sofa, a dining table with chairs, a potted plant, and a rug.

10. Las Clementinas

San Felipe, 0.2 km from El Machetazo Santa Ana

James

฿4,571

฿5,691 total

includes taxes & fees

28 Sept - 29 Sept

A rooftop pool area with lounge chairs and tables, surrounded by a city skyline at dusk.

A modern building with a central entrance, large pillars, and a reflective pathway leading to the entrance.

A living room with a sofa, armchairs, a coffee table, a console table with a mirror, and a tall floor lamp.

A modern living room with a large window, a yellow sofa, a black coffee table, and a decorative mirror.

11. Yoo Apartamento

Bella Vista, 2.9 km from El Machetazo Santa Ana

฿3,180

฿4,955 total

includes taxes & fees

26 Sept - 27 Sept

A multi-story building with balconies, arched windows, and decorative railings.

A multi-level atrium with wooden staircases, seating areas, and a decorative ceiling.

A rooftop swimming pool with lounge chairs, potted plants, and a view of a city skyline including a prominent building with a dome.

A spacious lobby with a wooden staircase, multiple seating areas, and a reception desk.

12. Central Hotel Panama Casco Viejo

San Felipe, 0.5 km from El Machetazo Santa Ana

Olga

฿6,322

฿6,954 total

includes taxes & fees

27 Sept - 28 Sept

A rooftop pool area with lounge chairs and a bar, overlooking a city skyline at sunset.

A modern hotel lobby with a glass railing, seating area, and contemporary lighting fixtures.

A spacious lobby with high ceilings, large windows, and modern lighting fixtures.

A rooftop terrace with outdoor seating, potted plants, and a view of a hill with buildings in the distance.

13. Marriott Panama Hotel

2.4 km from El Machetazo Santa Ana

Richard

฿5,597

฿6,157 total

includes taxes & fees

10 Oct - 11 Oct

A spacious living room with blue sofas, a marble coffee table, and framed pictures on the walls.

A hotel room with a large bed, a TV, a balcony with a view of the outside, and a window with decorative ironwork.

A bedroom with a large bed, white walls, and a view of a building through arched windows.

A blue building with arched windows and balconies, labeled 'Magnolia.'

14. Hotel Magnolia Boutique

San Felipe, 0.4 km from El Machetazo Santa Ana

Boris

฿2,474

฿2,721 total

includes taxes & fees

4 Oct - 5 Oct

A rooftop bar with a city skyline view, outdoor seating, and a bar area with bottles and glasses.

A room with a kitchenette, a sofa, a bed, and a mural with the phrase "Just Breathe".

A modern living room with a purple wall, two abstract paintings, a white sofa with colorful cushions, a wooden coffee table with books and bottles, and patterned floor tiles.

A hotel room with a large bed, a painting on the wall, a door, and a small table with a lamp.

15. Tantalo Hotel

San Felipe, 0.4 km from El Machetazo Santa Ana

Cassondra

฿2,513

฿2,764 total

includes taxes & fees

30 Sept - 1 Oct

A modern indoor pool area with clear blue water, lounge chairs, and a wall of plants.

A balcony with a view of the sea, a table with a vase and a candle, and a chair.

A modern kitchen with a central island, stainless steel appliances, and a dining area with black chairs.

A modern bedroom with a large window, a bed with white linens, a nightstand, and a painting on the wall.

16. Casco View Life Residences

Santa Ana, 0.2 km from El Machetazo Santa Ana

Ruben

฿1,999

฿3,192 total

includes taxes & fees

27 Sept - 28 Sept

A modern living room with a sofa, round black ottomans, and a vase of flowers. A cityscape is visible through the window.

A cozy outdoor seating area with a wooden bench and white tables, surrounded by lush greenery and potted plants.

A bar area with a long counter, multiple bar stools, and a television screen. There are large windows providing natural light and a view of the outdoors.

A rooftop swimming pool with a cityscape view, glass railings, and a modern architectural design.

17. Bristol Panama, a Registry Collection Hotel

Bella Vista, 3.2 km from El Machetazo Santa Ana

Juliet

฿7,010

฿7,711 total

includes taxes & fees

9 Oct - 10 Oct

A modern living room with a sofa, armchair, dining table, and kitchen area with a TV and appliances.

A modern living room with a glass dining table, black chairs, a grey sofa, and a large window with a city view.

A swimming pool with clear water, surrounded by high-rise buildings under a partly cloudy sky.

A modern bedroom with a bed, bedside tables, a nightstand, a wall-mounted TV, and a city view.

18. Modern Apartments at The Gray Prime Location

Campo Alegre, 3 km from El Machetazo Santa Ana

Tiyania

฿2,575

฿2,832 total

includes taxes & fees

26 Sept - 27 Sept

A hotel room with a bed, a desk with a computer, a chair, a mirror, and a staircase.

A spacious living area with a staircase leading to a loft, a large mirror, and a television.

A spacious living area with a staircase leading to a second floor, a sofa, a TV, and a dining area.

A balcony with a view of a city skyline, a river, and a large tree.

19. Hotel Bardot Boutique

San Felipe, 0.8 km from El Machetazo Santa Ana

Gary

฿2,663

฿2,930 total

includes taxes & fees

11 Oct - 12 Oct

A modern bathroom with a glass shower enclosure, a wooden door, and a herringbone-patterned floor.

A compact kitchen with a dining area, including a coffee maker, sink, and wooden chairs.

A multi-story building with balconies adorned with string lights, a sign reading "ZABAH", and a storefront named "CORCHO".

20. Corcho

San Felipe, 0.4 km from El Machetazo Santa Ana

Ashley

฿2,710

฿2,981 total

includes taxes & fees

24 Sept - 25 Sept

View all properties

Compare popular hotels close to El Machetazo Santa Ana

Property	Property class	Guest rating
La Isabela Suites	10.0 Exceptional 212 reviews	View
Hotel Plaza Herrera	9.8 Exceptional 48 reviews	View
Sofitel Legend Casco Viejo, Panama City	9.8 Exceptional 750 reviews	View
La Concordia Boutique Hotel	9.6 Exceptional 237 reviews	View
Hotel San Felipe	9.4 Exceptional 453 reviews	View

Top El Machetazo Santa Ana Hotel Reviews

Central Hotel Panama Casco Viejo

10/10 Excellent

"Desayuno variado y muy bueno. El staff dispuesto ayudarle y recommend lugares para ver. Recomendado 100%"

Hotel Caracas - Casco Viejo

10/10 Excellent

"We stayed one night there. Very comfortable location. The room was clean, nice shower, helpful and friendly staff, and they have good coffee in the lobby :)"

Hostal La Cigarra

8/10 Good

"Location is great, very comfortable and the instructions sent before the stay were useful. The room is clean and functional, and the stuff is very kind and helpful. The only thing to say is that there is no hot water in the shower, something that I expect to be informed about before booking the room."

Hotel San Felipe

10/10 Excellent

"This property is set in a great location and is very cute and clean. The bed was great. The staff was very nice and efficient without being overwhelming. We didn't eat at the restaurant because we did a lot of exploring but would definitely stay again. The only thing I would say needs some improvement is the wifi strength it wasn't always reliable."

Sofitel Legend Casco Viejo, Panama City

10/10 Excellent

"Sofitel Legend is a wonderful place to stay. The staff are amazing."

Hotel Magnolia Boutique

10/10 Excellent

"Muy buen lugar"

Hotel Faranda Express Soloy and Casino, a member of Radisson Individuals

8/10 Good

"Todo bien"

American Trade Hotel

10/10 Excellent

"The place is beautiful nice location the only thing is the church bells wake you up at 6:30 am but I think thats everywhere in the Casco Viejo."

Hotel Casa Panamá

8/10 Good

"Overall a good place to stay for exploring Panama. Lots of restaurants and activities walking distance."

Other attractions near El Machetazo Santa Ana

Amador Theater

Get tickets for a show at Amador Theater, a popular theatre in Panama City. Visit the shops and top-notch restaurants in this vibrant area.

See properties

Iglesia de la Merced

You can learn about the history of Panama City when you stop by Iglesia de la Merced. Visit the shops and top-notch restaurants in this vibrant area.

See properties

Danilo Perez Foundation

Enjoy the student vibe at Danilo Perez Foundation as part of your travels around Panama City. Visit the shops and top-notch restaurants in this vibrant area.

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Mola Museum

You can spend time exploring the galleries in Mola Museum in Panama City. You can enjoy the bars while in the area.

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Museo de la Esmeralda

You can spend time exploring the galleries in Museo de la Esmeralda during your travels in Panama City. You can enjoy the bars while in the area.

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Palacio de las Garzas

You can study the exhibits at Palacio de las Garzas, a museum with a storied past, during your travels to Panama City. Visit the shops and top-notch restaurants in this vibrant area.

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Metropolitan Cathedral of Panama

9.0/10 (793 reviews)

Metropolitan Cathedral of Panama is just one of the places to see in Panama City, so why not enjoy the other things to explore during your travels? Visit the shops and top-notch restaurants in this vibrant area.

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Independence Square

9.0/10 (62 reviews)

You can learn about the history of Panama City with a trip to Independence Square. Visit the shops and top-notch restaurants in this vibrant area.

See properties

Frequently asked questions

What's the area like around El Machetazo Santa Ana?

El Machetazo Santa Ana is located in Panama City. If you're looking for a convenient place to stay, take a look at the 517 hotels and other accommodation options you'll find within a mile.

Where is the best place to stay close to El Machetazo Santa Ana?

Adjacent to El Machetazo Santa Ana, Hotel Casa Panamá is one of the top choices for your stay based on our traveller data, and this hotel offers 2 restaurants and a nightclub. Other good choices close by include Central Hotel Panama Casco Viejo and Sofitel Legend Casco Viejo, Panama City.

How many hotels will I find close to El Machetazo Santa Ana?

Expedia has 517 hotels and other accommodation options within a mile from El Machetazo Santa Ana.

If I need to cancel the hotel reservation for my stay near El Machetazo Santa Ana, will I receive a refund?

Yes! Most hotel bookings are fully refundable as long as you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, you might be able to cancel it and get a refund within a 24-hour period of your booking. Add dates, click "Search", then filter by "fully refundable" to review the top deals on offer near El Machetazo Santa Ana.

What can I see and do near El Machetazo Santa Ana?

You'll want to browse the collections at Interoceanic Canal Museum, Biomuseo and Mola Museum. Explore landmarks like Iglesia del Carmen, Panama Canal Railway and Iglesia de la Merced. You can check out the local talent at National Theater, Amador Theater and Anita Villalaz Theater.

Search Hotels Near El Machetazo Santa Ana, Panama City

Change your mind

Treat yourself

Be picky

Check prices for these dates

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Our top choices for El Machetazo Santa Ana hotels

1. La Isabela Suites

2. Hotel Plaza Herrera

3. Sofitel Legend Casco Viejo, Panama City

4. La Concordia Boutique Hotel

5. Hotel San Felipe

6. Casa Mallet by Wynwood House

7. Amarla Boutique Hotel Casco Viejo Adults Only

8. Casa Lefevre By Wynwood House

9. American Trade Hotel

10. Las Clementinas

11. Yoo Apartamento

12. Central Hotel Panama Casco Viejo

13. Marriott Panama Hotel

14. Hotel Magnolia Boutique

15. Tantalo Hotel

16. Casco View Life Residences

17. Bristol Panama, a Registry Collection Hotel

18. Modern Apartments at The Gray Prime Location

19. Hotel Bardot Boutique

20. Corcho

Compare popular hotels close to El Machetazo Santa Ana

Top El Machetazo Santa Ana Hotel Reviews

Central Hotel Panama Casco Viejo

Hotel Caracas - Casco Viejo

Hostal La Cigarra

Hotel San Felipe

Sofitel Legend Casco Viejo, Panama City

Hotel Magnolia Boutique

Hotel Faranda Express Soloy and Casino, a member of Radisson Individuals

American Trade Hotel

Hotel Casa Panamá

Other attractions near El Machetazo Santa Ana

Amador Theater

Iglesia de la Merced

Danilo Perez Foundation

Mola Museum

Museo de la Esmeralda

Palacio de las Garzas

Metropolitan Cathedral of Panama

Independence Square

Frequently asked questions