A tropical island with palm trees and a clear blue sky.

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Panama Accommodation: Most Popular Cities to Stay

A coastal cityscape with high-rise buildings, a marina, and a clear blue sky.
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Panama City

Panama City

Check availability on Panama Luxury Hotels

This weekend
30 Oct - 1 Nov
Next weekend
6 Nov - 8 Nov

Our top choices for Panama luxury hotels

A poolside area with lounge chairs and a view of the ocean.

1. JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.2 out of 10, Wonderful, (1,002 reviews)
  • cleanliness
    Unwind in opulent waterfront luxury with 4 pristine pools and ocean-view dining in Panama City.
The price is ฿9,967
฿10,964 total
includes taxes & fees
21 Nov - 22 Nov
JW Marriott Panama
A modern living room with a sofa, round black ottomans, and a vase of flowers. A cityscape is visible through the window.

2. Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
5.0 star property
Bella Vista
9.2 out of 10, Wonderful, (1,000 reviews)
  • cleanliness
    Art deco elegance meets modern luxury in this Panama City hotel featuring 2 bars, a full-service spa, and an outdoor pool.
The price is ฿7,146
฿7,861 total
includes taxes & fees
13 Nov - 14 Nov
Bristol Panama, a Registry Collection Hotel
A spacious living area with a large sectional sofa, a coffee table, and a decorative rug. There is a large wall clock and a lamp on a side table.

3. Waldorf Astoria Panama

Waldorf Astoria Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,000 reviews)
  • cleanliness
    Panama City elegance at this Waldorf Astoria hotel with a full-service spa, outdoor pool, and refined dining in two upscale restaurants.
The price is ฿9,155
฿10,071 total
includes taxes & fees
14 Nov - 15 Nov
Waldorf Astoria Panama
A historic building with multiple balconies and a statue of a man on horseback.

4. American Trade Hotel

American Trade Hotel
4.5 star property
Casco Viejo
9.4 out of 10, Exceptional, (820 reviews)
  • cleanliness
    A colonial gem in Panama City offering luxurious comfort, exquisite dining, and personalised service in a historic district.
The price is ฿8,294
฿9,124 total
includes taxes & fees
1 Nov - 2 Nov
American Trade Hotel
A poolside area with covered seating and palm trees.

5. Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
4.5 star property
Bella Vista
8.8 out of 10, Excellent, (1,001 reviews)
  • cleanliness
    Indulge in Panama City luxury with an outdoor pool, full-service spa, and casino at this stylish hotel near Via Espana.
The price is ฿8,745
฿9,619 total
includes taxes & fees
18 Nov - 19 Nov
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
A modern hotel pool area with lounge chairs and a clear view of the ocean.

6. Hilton Panama

Hilton Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,001 reviews)
  • cleanliness
    Panama City sophistication meets relaxation with an attached winery, poolside dining, and a full-service spa offering couples' treatments.
The price is ฿8,868
฿9,755 total
includes taxes & fees
20 Nov - 21 Nov
Hilton Panama
Outdoor pool

7. Megapolis Hotel Panamá

Megapolis Hotel Panamá
5.0 star property
San Francisco
8.4 out of 10, Very good, (1,000 reviews)
  • cleanliness
    Indulgent pampering awaits at this Beaux Arts Panama City gem with spa, casino, and rooftop bar.
The price is ฿9,267
฿10,194 total
includes taxes & fees
23 Nov - 24 Nov
Megapolis Hotel Panamá
A poolside lounge area with two white cushioned chairs and a lantern, surrounded by palm trees and a view of the ocean at sunset.

8. The Buenaventura Golf & Beach Resort Panama, Autograph Collection

The Buenaventura Golf & Beach Resort Panama, Autograph Collection
5.0 star property
El Chiru
9.2 out of 10, Wonderful, (784 reviews)
  • cleanliness
    Immerse in beachfront opulence with 12 stunning pools, a full-service spa, and private beach access at this Panama golf resort.
The price is ฿7,529
฿8,282 total
includes taxes & fees
15 Nov - 16 Nov
The Buenaventura Golf & Beach Resort Panama, Autograph Collection
A modern lobby with a glass railing, a central staircase, and a view of the cityscape through large windows.

9. Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,138 reviews)
  • cleanliness
    Panama City hotel offers upscale comfort with spa, indoor pool, and pillowtop beds in San Francisco district.
The price is ฿5,061
฿5,567 total
includes taxes & fees
16 Nov - 17 Nov
Las Americas Golden Tower Panama
A rooftop pool area with lounge chairs and a bar, overlooking a city skyline at sunset.

10. Marriott Panama Hotel

Marriott Panama Hotel
4.0 star property
Panama City
9.2 out of 10, Wonderful, (1,001 reviews)
  • cleanliness
    Luxury redefined in Panama City with rooftop pool, premium dining, and concierge services to elevate your urban escape.
The price is ฿6,010
฿6,611 total
includes taxes & fees
21 Nov - 22 Nov
Marriott Panama Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Panama Hotel Reviews

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

8/10 Good
"Lindo lugar me volvería a hospedar"
nestor 2-night trip
Posted 5 hours ago
Hotel Riu Plaza Panama