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Our top choices for Santo Domingo Square hotels

Hotel Quadrifolio

Hotel Quadrifolio
4.5 star property
Cartagena Centro, 0.2 km from Santo Domingo Square
10.0 out of 10, Exceptional, (166 reviews)
"Location was perfect, right in Old Town. Staff was fantastic and attentive to all our needs and went out of their way to make our stay unique. The room took your breath away; very quite. The breakfast was so good. I would stay here in a heartbeat again. "
United States
John
Hotel Quadrifolio

Casa De Alba Hotel Boutique

Casa De Alba Hotel Boutique
5.0 star property
Cartagena Centro, 0.1 km from Santo Domingo Square
9.8 out of 10, Exceptional, (59 reviews)
"The hotel is beautiful, the staff so friendly and the breakfast was wonderful "
United States
Paige
The price is ฿8,366
฿8,366 total
4 Mar - 5 Mar
Casa De Alba Hotel Boutique

Hotel Casa Bianca By Faranda Boutique

Hotel Casa Bianca By Faranda Boutique
3.5 star property
Cartagena Walled City, 0.4 km from Santo Domingo Square
10.0 out of 10, Exceptional, (15 reviews)
"Amazing stay! Beautiful hotel, spotless rooms, and incredibly friendly staff. Kevin, Santiago and the kitchen staff were extremely helpful and accommodating. Everything was comfortable, well-maintained, and welcoming. Would absolutely stay here again—highly recommended!"
United States
Marjorie
The price is ฿7,963
฿7,963 total
4 Mar - 5 Mar
Hotel Casa Bianca By Faranda Boutique

Hotel Boutique Casona del Porvenir

Hotel Boutique Casona del Porvenir
3.0 star property
Cartagena Centro, 0.3 km from Santo Domingo Square
9.8 out of 10, Exceptional, (94 reviews)
"Staff was incredible, room was luxurious and clean"
Canada
Yul
The price is ฿8,451
฿8,451 total
4 Mar - 5 Mar
Hotel Boutique Casona del Porvenir

Palacio del Agua by Faranda Boutique

Palacio del Agua by Faranda Boutique
4.0 star property
Cartagena Centro, 0.3 km from Santo Domingo Square
9.8 out of 10, Exceptional, (20 reviews)
"The room was very clean and it offered a great view. Having multiple pools is always a bonus and you're staying in the heart of Walled City."
United States
Rickey
The price is ฿9,904
฿9,904 total
23 Mar - 24 Mar
Palacio del Agua by Faranda Boutique

Hotel Casa San Agustin

Hotel Casa San Agustin
4.5 star property
Cartagena Centro, 0.3 km from Santo Domingo Square
9.8 out of 10, Exceptional, (472 reviews)
"Great staff and beautiful room. Awesome location and breakfast "
Mexico
German
The price is ฿19,000
฿19,000 total
5 Mar - 6 Mar
Hotel Casa San Agustin

Casa Claver Loft Boutique Hotel

Casa Claver Loft Boutique Hotel
4.0 star property
Cartagena Centro, 0.2 km from Santo Domingo Square
9.8 out of 10, Exceptional, (601 reviews)
"Hotel is great, customer service, cleanliness, close to everything. Amazing stay! "
United States
Esperanza
The price is ฿8,850
฿8,850 total
15 Mar - 16 Mar
Casa Claver Loft Boutique Hotel

Casa Pestagua Relais Châteaux

Casa Pestagua Relais Châteaux
4.5 star property
Cartagena Centro, < 0.1 km from Santo Domingo Square
9.6 out of 10, Exceptional, (280 reviews)
"Great service "
United States
amir
The price is ฿15,000
฿15,000 total
15 Mar - 16 Mar
Casa Pestagua Relais Châteaux

Sophia Hotel By OxoHotel

Sophia Hotel By OxoHotel
4.0 star property
Cartagena Centro, 0.3 km from Santo Domingo Square
9.6 out of 10, Exceptional, (621 reviews)
"Everything was perfect. We highly recommend!"
United States
James
Sophia Hotel By OxoHotel

Amarla Boutique Hotel Cartagena

Amarla Boutique Hotel Cartagena
3.5 star property
Cartagena Centro, 0.1 km from Santo Domingo Square
9.6 out of 10, Exceptional, (55 reviews)
"The staff was freindly, helpful, gracious ... knew our names throughout our stay. We looked forward to breakfast every day! The ONLY down side was that the pool wasn't open. Otherwise we were comfortable and in awe of the beautiful Amarla."
United States
jennifer
Amarla Boutique Hotel Cartagena

Alfiz Hotel Boutique

Alfiz Hotel Boutique
3.0 star property
Cartagena Centro, 0.3 km from Santo Domingo Square
9.6 out of 10, Exceptional, (189 reviews)
"It was a good hotel good service. Our room was good but for breakfast, we had to hop over to another place. "
United States
anila
Alfiz Hotel Boutique

Sol de Alba Hotel Boutique

Sol de Alba Hotel Boutique
4.0 star property
Cartagena Walled City, 0.3 km from Santo Domingo Square
9.6 out of 10, Exceptional, (34 reviews)
"Everyone was amazing especially Guillermo. Breakfast top notch "
United States
Natalia
The price is ฿6,282
฿6,282 total
16 Mar - 17 Mar
Sol de Alba Hotel Boutique

Hotel Casa del Gobernador

Hotel Casa del Gobernador
4.5 star property
Cartagena Centro, 0.2 km from Santo Domingo Square
9.6 out of 10, Exceptional, (103 reviews)
"Wonderful boutique hotel where everybody is so helpful and nice. "
United States
Rob
The price is ฿8,508
฿8,508 total
15 Mar - 16 Mar
Hotel Casa del Gobernador

Casa Belle Cartagena Hotel Boutique

Casa Belle Cartagena Hotel Boutique
4.0 star property
San Diego, 0.5 km from Santo Domingo Square
9.8 out of 10, Exceptional, (10 reviews)
"Spectacular stay. Waldo and the entire staff made my husband and I feel so welcomed. The private grounds were a perfect location to unwind and still walking distance to all activities/restaurants/shopping/night life. We will surely return for another peaceful and regenerative vacation. "
United States
Yennie
Casa Belle Cartagena Hotel Boutique

Hotel Casa La Mantilla by Faranda Boutique

Hotel Casa La Mantilla by Faranda Boutique
4.0 star property
Cartagena Centro, < 0.1 km from Santo Domingo Square
9.4 out of 10, Exceptional, (149 reviews)
"The room was incredibly comfortable, and the staff was beyond amazing. We felt completely safe and at home, and the experience, especially the breakfast, made our trip 10x better. Thank you, Hotel Casa La Mantilla by Faranda Boutique, for the incredible service, beautiful rooms, and perfect location! "
United States
Matthew
The price is ฿6,280
฿6,280 total
23 Mar - 24 Mar
Hotel Casa La Mantilla by Faranda Boutique

Casa Carolina Luxury Wellness Hotel

Casa Carolina Luxury Wellness Hotel
4.5 star property
Cartagena Centro, 0.2 km from Santo Domingo Square
9.6 out of 10, Exceptional, (36 reviews)
"The staff were very nice"
United States
Raymond
Casa Carolina Luxury Wellness Hotel

Leones de Alba Hotel Boutique

Leones de Alba Hotel Boutique
5.0 star property
Cartagena Centro, 0.1 km from Santo Domingo Square
9.4 out of 10, Exceptional, (65 reviews)
"Super friendly helpful staff, room was really clean, would definitely stay here again."
Canada
Peter
The price is ฿6,951
฿6,951 total
16 Mar - 17 Mar
Leones de Alba Hotel Boutique

Casa del Arzobispado Hotel

Casa del Arzobispado Hotel
4.0 star property
Cartagena Centro, 0.2 km from Santo Domingo Square
9.4 out of 10, Exceptional, (331 reviews)
"definitely a great place"
United States
Barbara A
Casa del Arzobispado Hotel

Privado Designer Boutique Hotel

Privado Designer Boutique Hotel
4.0 star property
San Diego, 0.5 km from Santo Domingo Square
9.6 out of 10, Exceptional, (139 reviews)
"The staff was kind and helpful, the property is BEAUTIFUL, the location is excellent and get the breakfast - it was a perfect start to the day. I would absolutely stay here again!"
Canada
Priya
Privado Designer Boutique Hotel

Cinco Quintas Hotel Boutique

Cinco Quintas Hotel Boutique
4.0 star property
Cartagena Centro, 0.3 km from Santo Domingo Square
9.4 out of 10, Exceptional, (254 reviews)
"In a word, amazing. Stayed in the 2 bedroom family suite; two beautiful rooms and a kitchen connected by a beautiful private courtyard. Comfort and design were fantastic. Good service and onsite dinning as well. "
Canada
Matthew
The price is ฿8,164
฿8,164 total
4 Mar - 5 Mar
Cinco Quintas Hotel Boutique
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Santo Domingo Square Hotel Reviews

Hotels near other Santo Domingo Square attractions

Frequently asked questions

What's the area like around Santo Domingo Square?
Santo Domingo Square is located in a historic area of Cartagena known for its beautiful beaches. If you're looking for a convenient place to stay, take a look at the 1182 hotels and other accommodation options you'll find within a mile.
What's the best hotel to stay near Santo Domingo Square?
Adjacent to Santo Domingo Square, Bastión Luxury Hotel is one of the top choices for your stay based on our traveller data, and this hotel offers a full-service spa and free breakfast. Other good choices within a short distance include Hyatt Regency Cartagena and Sofitel Legend Santa Clara Cartagena.
How many hotels are there close to Santo Domingo Square?
Expedia has 1182 hotels and other accommodation options within a mile from Santo Domingo Square.
If I need to cancel the hotel reservation for my stay near Santo Domingo Square, will I receive a refund?
Yes! The majority of room reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Put your dates in and click on "Search", then use the "fully refundable" filter to get the top deals on offer near Santo Domingo Square.
What can I see and do near Santo Domingo Square?
Study the collections at Palace of the Inquisition Cartagena Historical Museum, Cartagena's Gold Museum or Palacio de la Inquisicion. Plaza Santo Domingo, San Pedro Claver Church and Convent and Clock Tower are monuments to see when you're exploring the area around Santo Domingo Square. You can wander around Parque de La Marina, El Cabrero Park or Cerro de La Popa if you want a dose of fresh air.