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Check prices for these dates

Tonight
29 Apr - 30 Apr
Tomorrow
30 Apr - 1 May
This weekend
1 May - 3 May
Next weekend
8 May - 10 May

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Our top choices for Santa Cruz hotels

Exterior

Surbackpackers

Surbackpackers
3.0 star property
Santa Cruz
The price is ฿732
฿732 total
4 May - 5 May
Surbackpackers
Outdoor pool

Sun Hotel

Sun Hotel
3.5 star property
Santa Cruz
8.2 out of 10, Very good, (368 reviews)
"It’s close to the airport and a good spot to rest if you have a long layover. "
United States
Jon
The price is ฿3,186
฿3,186 total
8 May - 9 May
Sun Hotel
Restaurant

Prince Hotel

Prince Hotel
3.0 star property
Santa Cruz
9.4 out of 10, Exceptional, (3 reviews)
"Nice place "
United States
Marco
The price is ฿1,756
฿1,821 total
5 May - 6 May
Prince Hotel
Outdoor pool, open 9:00 AM to 8:00 PM, pool loungers

Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (94 reviews)
"The location was very good, close to several restaurants within walking distance."
United States
Yadin
The price is ฿1,268
฿1,268 total
3 May - 4 May
Premium Suites Deluxe Aparthotel Equipetrol
Miscellaneous

Ibis Santa Cruz DE LA Sierra

Ibis Santa Cruz DE LA Sierra
3.0 star property
Santa Cruz
9.6 out of 10, Exceptional, (108 reviews)
"Nice place"
United States
Juan Carlos
The price is ฿1,785
฿1,785 total
2 May - 3 May
Ibis Santa Cruz DE LA Sierra
Standard Suite, 1 Queen Bed | Hypo-allergenic bedding, down duvets, desk, laptop workspace

Equipetrol Suites Apart Hotel

Equipetrol Suites Apart Hotel
2.5 star property
Santa Cruz
8.8 out of 10, Excellent, (13 reviews)
"Perfect hotel"
Turkey
Yener
The price is ฿1,616
฿1,616 total
3 May - 4 May
Equipetrol Suites Apart Hotel
Outdoor pool, pool loungers

Hotel Cortez

Hotel Cortez
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (135 reviews)
"Lovely hotel. Great room, location, staff and amenities. "
Norway
Solvei Emily Brekke
The price is ฿3,482
฿3,482 total
22 May - 23 May
Hotel Cortez
Front of property

Chairú Eco Hotel

Chairú Eco Hotel
3.5 star property
Santa Cruz
9.4 out of 10, Exceptional, (62 reviews)
"Clean and close to the malls and restaurants "
United States
Luis
The price is ฿1,829
฿1,829 total
2 May - 3 May
Chairú Eco Hotel
1 bedroom, in-room safe, desk, iron/ironing board

Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz
3.5 star property
Santa Cruz
8.6 out of 10, Excellent, (101 reviews)
"Place is clean , safe area , walking distance to shops "
United States
Nataly
The price is ฿878
฿878 total
3 May - 4 May
Apart Hotel Premium Suites Santa Cruz
Triple Room | Free WiFi

Hotel Las Américas

Hotel Las Américas
3.0 star property
Santa Cruz
7.6 out of 10, Good, (7 reviews)
"Very clean room and great staff"
Canada
Stanley
The price is ฿1,124
฿1,124 total
2 May - 3 May
Hotel Las Américas
Reception

Urban Suites

Urban Suites
3.0 star property
Santa Cruz
10.0 out of 10, Exceptional, (1 review)
"What an amazing unit. I was very comfortable and I felt like being in my own home. The area was very nice, clean and safe as well. Recommendable 100%"
Canada
Jose
The price is ฿1,788
฿1,788 total
3 May - 4 May
Urban Suites
Double Room, 1 Queen Bed | Premium bedding, down duvets, minibar, blackout curtains

Hotel G

Hotel G
3.5 star property
Santa Cruz
7.8 out of 10, Good, (106 reviews)
"Excelente Hotel "
Mexico
JACOB
The price is ฿1,165
฿1,165 total
29 May - 30 May
Hotel G
Junior Room, 1 King Bed | Egyptian cotton sheets, premium bedding, pillow-top beds, minibar

HOTEL OSHO

HOTEL OSHO
3.5 star property
Santa Cruz
9.4 out of 10, Exceptional, (49 reviews)
"Room was great and staff were very accommodating!"
Canada
David
The price is ฿1,862
฿1,862 total
15 May - 16 May
HOTEL OSHO
Seasonal outdoor pool

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (370 reviews)
"Great"
United States
Maria helena
The price is ฿4,844
฿4,844 total
29 May - 30 May
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Living area

Posada Express Fast Check

Posada Express Fast Check
3.0 star property
Santa Cruz
7.8 out of 10, Good, (7 reviews)
"They nevershow up for let me in, i call many times and after 5 or 6 calls they answer saying someone going to be there in 15 for let me in. I wait 25 minutes and not body came. I went to other hotel because this is just regular house. No happy with this "hotel" im giving one because dont allow me to put -5 stars. "
United States
Nico
The price is ฿1,626
฿1,788 total
1 May - 2 May
Posada Express Fast Check
Outdoor pool

Mirador del Cielo

Mirador del Cielo
3.0 star property
Santa Cruz
4.0 out of 10, (1 review)
The price is ฿819
฿819 total
1 May - 2 May
Mirador del Cielo
Lounge

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (268 reviews)
"Convenient location clean rooms good breakfast with a view "
Canada
Jesus Enrique Cabello
The price is ฿3,040
฿3,040 total
15 May - 16 May
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Premium Room, 1 Queen Bed, Bathtub | Minibar, in-room safe, individually decorated, individually furnished

Cosmopolitano Hotel Boutique

Cosmopolitano Hotel Boutique
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (130 reviews)
"Best ever hotel in Santa Cruz, dedicated and accommodating staff!!! Great rooms!!!"
United States
Marcelo
The price is ฿2,300
฿2,300 total
18 May - 19 May
Cosmopolitano Hotel Boutique
Outdoor pool

AMERICA APARTMENTS

AMERICA APARTMENTS
3.0 star property
Santa Cruz
10.0 out of 10, Exceptional, (1 review)
"Clean room, great staff "
Canada
Peter
The price is ฿1,788
฿1,788 total
1 May - 2 May
AMERICA APARTMENTS
Reception

Lido Hotel

Lido Hotel
3.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (40 reviews)
"Lovely stay for a night. Great location within easy walking distance to the center."
United States
Gabrielle
The price is ฿1,340
฿1,340 total
1 May - 2 May
Lido Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Holiday Rentals in Santa Cruz

Aparthotel
Outdoor pool, open 9:00 AM to 8:00 PM, pool loungers
Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (94 reviews)
"The location was very good, close to several restaurants within walking distance."
Premium Suites Deluxe Aparthotel Equipetrol
See all holiday rentals
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Where to stay in Santa Cruz

Find the best Santa Cruz areas for the activities you enjoy most. Learn more about Santa Cruz
Learn more about Santa Cruz

Hamacas

When in Hamacas, you can plan a visit to Santa Cruz Zoo and Las Brisas Shopping Center, some noteworthy sights in the nearby area.

Stay near popular Santa Cruz attractions

Plaza 24 de Septiembre

4.4/5 (164 reviews)
Plaza 24 de Septiembre buzzes with local culture beneath swaying palms and colonial architecture. Climb the Cathedral's bell tower for spectacular city views while sampling authentic Bolivian coffee from vendors.
See properties

Learn more about Santa Cruz

Tropical energy pulses through Plaza 24 de Septiembre, where locals gather under palm trees and the Metropolitan Cathedral's twin towers stand watch. Biocentro Güembé offers rainforest trails with butterfly gardens, while the massive Ventura Mall provides air-conditioned shopping when afternoon temperatures climb.

See all hotels in Santa Cruz

Top Santa Cruz Hotel Reviews

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

10/10 Excellent
"It's good place, with good surroundings."
Christopher 1-night trip
Posted 8 hours ago
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

More cheap stays in Santa Cruz

Equipetrol Suites Apart Hotel

Equipetrol Suites Apart Hotel

Equipetrol Santa Cruz Departamento de Santa Cruz
The price is ฿1,616 per night from 3 May to 4 May
฿1,616
฿1,616 total
3 May - 4 May

Frequently asked questions

What's the best place for a stay in Santa Cruz?
Ibis Santa Cruz DE LA Sierra is one of the top choices for your stay based on our traveller data. This hotel offers a restaurant and free parking. Other good choices for your stay include Sun Hotel and Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel. See all available top hotels, or vacation rentals in Santa Cruz.
What are some of the best holiday rentals that Santa Cruz has to offer?
Casa Vida: This highly rated holiday home rental in Santa Cruz is located in a rural location, and has an outdoor pool, a patio and a BBQ to put you at ease in your new surroundings. It has 3 bedrooms, as well as a kitchen with a full-sized fridge, a stovetop and a microwave, so that you can cook with friends or family. Kick off your shoes and enjoy yourself with a private garden and a selection of games. See all vacation rentals in Santa Cruz.
If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you booked a non-refundable reservation, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.
What's the best budget-friendly accommodation in Santa Cruz?
Based on our traveller reviews, residencial francia - Hostel is a top choice for a less expensive stay. Other choices for your budget-friendly stay include Travelero Hostel ans Tours and Urubo Suite - Hostel. View all budget hotels in Santa Cruz.
What's the best family accommodation in Santa Cruz?
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel is a hotel with 2 restaurants and free parking, and it's a top choice on Expedia for families. Other choices for your child-friendly holiday include Marriott Santa Cruz de la Sierra Hotel and Camino Real Hotel. Also, attractions such as Santa Cruz Zoo and Play Land Amusement Park are fun for children of all ages. Find more child-friendly accommodations in Santa Cruz.
What's the best LGBTQ-friendly accommodation in Santa Cruz?
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia is a top LGBTQ-friendly hotel that features free breakfast and free Wi-Fi. Swissôtel Santa Cruz De La Sierra and Radisson Hotel Santa Cruz are other good choices for your holiday. See all available hotels listed as LGBTQ-friendly in Santa Cruz.
What's the best dog-friendly accommodation option in Santa Cruz?
Casa Por Temporadas is a top dog-friendly guest house, and offers an outdoor pool along with in-room kitchens for its human guests. Two other good options for you and your pet's trip include Ibis Santa Cruz DE LA Sierra and Prince Hotel. See more pet-friendly hotel accommodations in Santa Cruz.
What's the best luxury accommodation option in Santa Cruz?
Marriott Santa Cruz de la Sierra Hotel is a luxury hotel with a full-service spa and a rooftop terrace, and it's a popular choice for Expedia travellers looking for an elegant place to stay. Camino Real Hotel and Hampton by Hilton Santa Cruz/Equipetrol, Bolivia are other upscale choices for your holiday. Find more luxury hotels in Santa Cruz.
What are some accommodation options with pools in Santa Cruz?
Yotau All Suites Hotel is a top hotel with 2 outdoor swimming pools, a children's pool and 2 restaurants. A couple of other options that feature an on-site pool include Buganvillas Hotel Suites & Spa and Royal Lodge Hotel. View all hotels with pools in Santa Cruz.
What is the best spa hotel in Santa Cruz?
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel is a top spa hotel featuring a fitness centre, a hair salon and a bar. Enjoy a facial, body scrub or hydrotherapy at Los Tajibos Club Spa. Other popular spa hotels in Santa Cruz include Marriott Santa Cruz de la Sierra Hotel and Camino Real Hotel. See all spa hotels in Santa Cruz.
What's it like to stay in Santa Cruz?
Visitors to Santa Cruz will definitely enjoy the shopping. Tourists can also enjoy the city's cafés, zoo and cathedral. In Santa Cruz, there are 286 hotels and other accommodation options to choose from. Find out more about Santa Cruz.
What is there to see in Santa Cruz?
Cultural venues include Cine Center, Sacred Art Museum and Ethno-folkloric Museum. Landmarks like San Lorenzo Cathedral, Plaza 24 de Septiembre and Blacutt Square might be worth a visit. Natural beauty is on display at Arenal Park, Guembe Biocenter and Lomas de Arena Regional Park. Take a look at what more there is to see and do in Expedia's Santa Cruz guide.
How should I get around Santa Cruz?
If you want to venture outside the area, hop on a train at Santa Cruz de la Sierra Station. If you want to venture out around the area, you may want a rental car in Santa Cruz for your journey.
What's the weather like in Santa Cruz?
The hottest months are usually October and November, with an average temperature of 26°C, while the coldest months are June and July, with an average of 21°C. Average annual precipitation for Santa Cruz is 1208 mm.