Santa Ana Packages (Flight + Hotel)

Book a Hotel + Flight or Car together to unlock savings

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    Better together
    Save up to ฿4,531 when you book a flight and hotel together*
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    Find the right fit
    With over 300,000 hotels worldwide, it's easy to create a perfect package
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    Rest easy
    Plan, book, and manage your trip all in one place

Top hotels in Santa Ana

Barceló Guatemala City
Barceló Guatemala City
4.5 out of 5
7 Avenida 15-45, Zona 9, Guatemala City, Guatemala
Fully refundableReserve now, pay when you stay
The price is ฿2,518 per night from 1 Jul to 2 Jul
฿2,518
฿3,072 total
1 Jul - 2 Jul
includes taxes & fees
9/10 Wonderful! (2,878 reviews)
"Hotel and staff were perfect! Pool was great. Restaurants were delicious. Breakfast buffet was good. Dinner buffet could use some improvement."

Reviewed on 27 Jun 2025

Barceló Guatemala City
Hotel Museo Spa Casa Santo Domingo
Hotel Museo Spa Casa Santo Domingo
4.5 out of 5
3a Calle Oriente No 28 A, Antigua Guatemala, Sacatepequez
Fully refundableReserve now, pay when you stay
9.2/10 Wonderful! (1,003 reviews)
"A beautiful property, the steam room could be warmer and the pool was under construction when we were there. The staff were amazing, the property is beautiful and immaculately kept, parking was easy and convenient and the food was excellent. Highly recommend."

Reviewed on 25 Jun 2025

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Hotel Museo Spa Casa Santo Domingo
Wyndham Garden Guatemala City
Wyndham Garden Guatemala City
4 out of 5
1a Avenida 12-46 Zona 10, Guatemala City, Guatemala
Fully refundableReserve now, pay when you stay
The price is ฿3,120 per night from 4 Jul to 5 Jul
฿3,120
฿3,807 total
4 Jul - 5 Jul
includes taxes & fees
9/10 Wonderful! (1,436 reviews)
"Clean , people friendly, the service was amazing"

Reviewed on 25 Jun 2025

Wyndham Garden Guatemala City
See all 1,126 properties in Santa Ana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santa Ana holiday package cost?
You can pick up a holiday package to this destination on Expedia. However, how much your holiday to Santa Ana costs will depend on the season, hotel choice and length of stay.
What are the cheapest months to go to Santa Ana?
If you'd like to snag a cheap Santa Ana holiday package, consider visiting in June, September and October. You'll usually find better prices on accommodation and flights during these months --- perfect for a budget-friendly break.
How many days is enough for Santa Ana?
Generally, a handful of days is enough to tick off the main attractions during your Santa Ana holiday. However, if you'd like to have time to relax or go on day trips, consider extending your itinerary.
How to find the best Santa Ana package deals?
Begin your search for a Santa Ana package deal by entering your destination and preferred trip dates under our "Packages" tab. Then apply some filters, like "Property type" and "Popular locations," to tailor the results to your exact style. You can also sort by "Package discount" and discover offers that come with unbeatable savings. If you don't find the ideal Santa Ana package deal straight away, just play around with your dates and search again. Remember that deals are only available for a limited time, so book early and get your Santa Ana adventure underway.
Is it cheaper to book a Santa Ana holiday as a package?
An Expedia holiday package could land you great savings when compared to arranging hotels and flights individually. Better still, you can customise your Santa Ana trip to fit your exact style. Choose your preferred flight time, select the hotel type and add a car rental. Browse our bundle deals and find out how much you can save.
When to book a holiday package to Santa Ana?
If you're considering a spontaneous Santa Ana trip, check out our last-minute deals that can be booked up to a week before you take off. Don't want to leave things to the last minute? You can score incredible deals on your flights and hotels by booking well in advance.
How to plan a trip to Santa Ana?

  1. Pick your travel dates: What you'd like to do in Santa Ana and your preferred season can help you decide when to travel.
  2. Work out your budget: Make sure you have enough money to cover everything from meals and transportation to flights and activities. Your hotel will probably be the largest expense during your trip to Santa Ana.
  3. Decide how long to go for: Now that you're more familiar with Santa Ana, you can work out the ideal length of your break. Create a rough plan and give yourself enough time to get through everything on your must-do list.
  4. Bundle your accommodation and airfare: After you've nailed down your trip dates and duration, book the perfect Santa Ana holiday package for you.

Popular places to visit

Santa Catalina Arch

Santa Catalina Arch

4.5/5(2 reviews)

Find out about the history of Antigua Guatemala when you spend time at Santa Catalina Arch. Discover the volcano viewpoints and shops in this family-friendly area.

Santa Catalina Arch

Things to do

Lake Atitlan One Day Tour from Antigua

Lake Atitlan One Day Tour from Antigua

฿2,981
per adult
96% of travellers recommend
Lake Atitlan One Day Tour from Antigua
Antigua ATV Sunset Tour

Antigua ATV Sunset Tour

฿2,106
per adult
100% of travellers recommend
Antigua ATV Sunset Tour
Tour in Hobbitenango on ATV or UTV

Tour in Hobbitenango on ATV or UTV

฿2,430
per adult
100% of travellers recommend
Tour in Hobbitenango on ATV or UTV
See all activities in Antigua Guatemala
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.