Santa Ana Packages (Flight + Hotel)

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to ฿4,531 when you book a flight and hotel together*

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Top hotels in Santa Ana

Barceló Guatemala City

Barceló Guatemala City

4.5 out of 5
7 Avenida 15-45, Zona 9 Guatemala City Guatemala
Fully refundableReserve now, pay when you stay
The price is ฿2,512 per night from 14 Dec to 15 Dec
฿2,512
฿3,065 total
14 Dec - 15 Dec
includes taxes & fees
9/10 Wonderful! (3,083 reviews)
The room b was nice but the bathroom ugly because a lot of water comes out when taken a shower

Reviewed on 14 Nov 2025

Barceló Guatemala City
Hotel Museo Spa Casa Santo Domingo

Hotel Museo Spa Casa Santo Domingo

4.5 out of 5
3a Calle Oriente No 28 A Antigua Guatemala Sacatepequez
Fully refundableReserve now, pay when you stay
The price is ฿8,757 per night from 18 Nov to 19 Nov
฿8,757
฿11,080 total
18 Nov - 19 Nov
includes taxes & fees
9.2/10 Wonderful! (1,010 reviews)
This place is absolutely amazing, from the staff, room, food, everything was unbelievable

Reviewed on 15 Nov 2025

Hotel Museo Spa Casa Santo Domingo
Wyndham Garden Guatemala City

Wyndham Garden Guatemala City

4 out of 5
1a Avenida 12-46 Zona 10 Guatemala City Guatemala
Fully refundableReserve now, pay when you stay
The price is ฿3,020 per night from 14 Dec to 15 Dec
฿3,020
฿3,684 total
14 Dec - 15 Dec
includes taxes & fees
9/10 Wonderful! (1,592 reviews)
Hotel was beautiful the front desk staff was helpful! Great hotel

Reviewed on 16 Nov 2025

Wyndham Garden Guatemala City
See all 1,218 properties in Santa Ana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santa Ana holiday package cost?
You can pick up a holiday package to this destination on Expedia. However, how much your holiday to Santa Ana costs will depend on the season, hotel choice and length of stay.
What are the cheapest months to go to Santa Ana?
If you'd like to snag a cheap Santa Ana holiday package, consider visiting in June, September and October. You'll usually find better prices on accommodation and flights during these months — perfect for a budget-friendly break.
How many days is enough for Santa Ana?
Generally, a handful of days is enough to tick off the main attractions during your Santa Ana holiday. However, if you'd like to have time to relax or go on day trips, consider extending your itinerary.
How to find the best Santa Ana package deals?
Begin your search for a Santa Ana package deal by entering your destination and preferred trip dates under our "Packages" tab. Then apply some filters, like "Property type" and "Popular locations," to tailor the results to your exact style. You can also sort by "Package discount" and discover offers that come with unbeatable savings. If you don't find the ideal Santa Ana package deal straight away, just play around with your dates and search again. Remember that deals are only available for a limited time, so book early and get your Santa Ana adventure underway.
Is it cheaper to book a Santa Ana holiday as a package?
An Expedia holiday package could land you great savings when compared to arranging hotels and flights individually. Better still, you can customise your Santa Ana trip to fit your exact style. Choose your preferred flight time, select the hotel type and add a car rental. Browse our bundle deals and find out how much you can save.
When to book a holiday package to Santa Ana?
If you're considering a spontaneous Santa Ana trip, check out our last-minute deals that can be booked up to a week before you take off. Don't want to leave things to the last minute? You can score incredible deals on your flights and hotels by booking well in advance.
How to plan a trip to Santa Ana?

  1. Pick your travel dates: What you'd like to do in Santa Ana and your preferred season can help you decide when to travel.
  2. Work out your budget: Make sure you have enough money to cover everything from meals and transportation to flights and activities. Your hotel will probably be the largest expense during your trip to Santa Ana.
  3. Decide how long to go for: Now that you're more familiar with Santa Ana, you can work out the ideal length of your break. Create a rough plan and give yourself enough time to get through everything on your must-do list.
  4. Bundle your accommodation and airfare: After you've nailed down your trip dates and duration, book the perfect Santa Ana holiday package for you.

Popular places to visit

Santa Catalina Arch

Santa Catalina Arch

Find out about the history of Antigua Guatemala when you spend time at Santa Catalina Arch. Discover the volcano viewpoints and shops in this romantic area.

Santa Catalina Arch

Things to do

From Antigua: 2-Day Acatenango Volcano Hiking Tour with Food

From Antigua: 2-Day Acatenango Volcano Hiking with Guide

฿1,584
per adult
From Antigua: 2-Day Acatenango Volcano Hiking with Guide
Hike to Pacaya Volcano from Antigua

Hike to Pacaya Volcano from Antigua

฿1,138
per adult
84% of travellers recommend
Hike to Pacaya Volcano from Antigua
From Antigua: Pacaya Volcano Trek

From Antigua: Pacaya Volcano Trek

฿748
per adult
86% of travellers recommend
From Antigua: Pacaya Volcano Trek
See all activities in Antigua Guatemala
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.