Santa Ana Packages (Flight + Hotel)

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to ฿4,531 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Top hotels in Santa Ana

Casa Buho B&B

Casa Buho B&B

3 out of 5
77 Calle del Agua Antigua Guatemala Guatemala
Fully refundableReserve now, pay when you stay
The price is ฿2,040 per night from 18 Feb to 19 Feb
฿2,040
฿2,489 total
18 Feb - 19 Feb
includes taxes & fees
9.2/10 Wonderful! (50 reviews)
All of the above. Can’t say enough about Miguel as well as all the staff very pleasant and more than accommodating. We had the room upstairs in the back with an amazing view of the volcano erupting regularly day and night. We Invited other guest to see the view. Spectacular to see surprised it’s ...

Reviewed on 15 Feb 2026

Casa Buho B&B
Barceló Guatemala City

Barceló Guatemala City

4.5 out of 5
7 Avenida 15-45, Zona 9 Guatemala City Guatemala
The price is ฿2,751 per night from 2 Mar to 3 Mar
฿2,751
฿3,356 total
2 Mar - 3 Mar
includes taxes & fees
9.2/10 Wonderful! (3,218 reviews)
The room was clean and spacious. Staff at the hotel were courteous and very helpful.

Reviewed on 17 Feb 2026

Barceló Guatemala City
Wyndham Garden Guatemala City

Wyndham Garden Guatemala City

4 out of 5
1a Avenida 12-46 Zona 10 Guatemala City Guatemala
Fully refundableReserve now, pay when you stay
The price is ฿2,784 per night from 15 Mar to 16 Mar
฿2,784
฿3,397 total
15 Mar - 16 Mar
includes taxes & fees
9.2/10 Wonderful! (1,697 reviews)
The

Reviewed on 17 Feb 2026

Wyndham Garden Guatemala City
See all 1,189 properties in Santa Ana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santa Ana holiday package cost?
You can pick up a holiday package to this destination on Expedia. However, how much your holiday to Santa Ana costs will depend on the season, hotel choice and length of stay.
What are the cheapest months to go to Santa Ana?
If you'd like to snag a cheap Santa Ana holiday package, consider visiting in June, September and October. You'll usually find better prices on accommodation and flights during these months — perfect for a budget-friendly break.
How many days is enough for Santa Ana?
Generally, a handful of days is enough to tick off the main attractions during your Santa Ana holiday. However, if you'd like to have time to relax or go on day trips, consider extending your itinerary.
How to find the best Santa Ana package deals?
Begin your search for a Santa Ana package deal by entering your destination and preferred trip dates under our "Packages" tab. Then apply some filters, like "Property type" and "Popular locations," to tailor the results to your exact style. You can also sort by "Package discount" and discover offers that come with unbeatable savings. If you don't find the ideal Santa Ana package deal straight away, just play around with your dates and search again. Remember that deals are only available for a limited time, so book early and get your Santa Ana adventure underway.
Is it cheaper to book a Santa Ana holiday as a package?
An Expedia holiday package could land you great savings when compared to arranging hotels and flights individually. Better still, you can customise your Santa Ana trip to fit your exact style. Choose your preferred flight time, select the hotel type and add a car rental. Browse our bundle deals and find out how much you can save.
When to book a holiday package to Santa Ana?
If you're considering a spontaneous Santa Ana trip, check out our last-minute deals that can be booked up to a week before you take off. Don't want to leave things to the last minute? You can score incredible deals on your flights and hotels by booking well in advance.
How to plan a trip to Santa Ana?

  1. Pick your travel dates: What you'd like to do in Santa Ana and your preferred season can help you decide when to travel.
  2. Work out your budget: Make sure you have enough money to cover everything from meals and transportation to flights and activities. Your hotel will probably be the largest expense during your trip to Santa Ana.
  3. Decide how long to go for: Now that you're more familiar with Santa Ana, you can work out the ideal length of your break. Create a rough plan and give yourself enough time to get through everything on your must-do list.
  4. Bundle your accommodation and airfare: After you've nailed down your trip dates and duration, book the perfect Santa Ana holiday package for you.

Popular places to visit

Recent trip to Antigua, Guatemala.

Santa Catalina Arch

Find out about the history of Antigua Guatemala when you spend time at Santa Catalina Arch. Discover the volcano viewpoints and shops in this romantic area.

Santa Catalina Arch

Things to do

Viewpoint

Lake Atitlan Day Tour From Antigua

฿4,139
per adult
100% of travellers recommend
Lake Atitlan Day Tour From Antigua
Antigua: ATV Guided Sunset Tour

Antigua: ATV Guided Sunset Tour

฿2,069
per adult
100% of travellers recommend
Antigua: ATV Guided Sunset Tour
Mold around 120g of chocolates

Bean-to-Bar Chocolate Workshop in ChocoMuseo Antigua

฿1,034
per adult
100% of travellers recommend
Bean-to-Bar Chocolate Workshop in ChocoMuseo Antigua
See all activities in Antigua Guatemala
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.