Otay Mesa Travel Guide
San Diego
Visit Otay Mesa
Stay near popular Otay Mesa attractions
Things to do
Tijuana: Guided City Tour with Local Food and Beer Tasting
฿3,762
per adult
Tijuana Downtown Self Guided Walking Tour
฿320
per adult
100% of travellers recommend
Stand up Paddle Board Lesson on The San Diego Bay
฿821
per adult
100% of travellers recommend
Top hotels in Otay Mesa
Wyndham San Diego Bayside
1355 N Harbor Drive San Diego CA
The price is ฿5,377 per night from 19 Jul to 20 Jul
฿5,377
฿7,396 total
19 Jul - 20 Jul
includes taxes & fees
Stay at this business-friendly hotel in San Diego. Enjoy free Wi-Fi, 3 restaurants and breakfast (surcharge). Our guests praise the pool and the restaurant in ...
8.4/10 Very good! (6,287 reviews)
"Balcony view was amazing. No microwave. Friendly staff. Clean room.Walking distance to Seaport Village was close by, along with other attractions. Will plan on staying here again."
Reviewed on 10 Jul 2026
Paradise Point Resort & Spa
1404 Vacation Rd San Diego CA
The price is ฿9,319 per night from 9 Aug to 10 Aug
฿9,319
฿12,478 total
9 Aug - 10 Aug
includes taxes & fees
Stay at this beach resort in San Diego. Enjoy free Wi-Fi, 5 outdoor pools and a full-service spa. Our guests praise the pool and the helpful staff in their reviews. ...
8.8/10 Excellent! (2,723 reviews)
"We love the place we will go back"
Reviewed on 9 Jul 2026
Hard Rock Hotel San Diego
207 5th Ave San Diego CA
The price is ฿5,548 per night from 19 Jul to 20 Jul
฿5,548
฿8,045 total
19 Jul - 20 Jul
includes taxes & fees
Stay at this hotel in San Diego. Enjoy free Wi-Fi, 2 restaurants and a nightclub. Our guests praise the helpful staff and the convenient parking in their reviews. ...
9/10 Wonderful! (4,016 reviews)
"Clean room. The location was perfect for our visit(going to Petco park). The pool is heated which I wish I would have known ahead of time, it looked great. Everyone was friendly."
Reviewed on 10 Jul 2026
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
2485 Hotel Circle Place San Diego CA
The price is ฿4,246 per night from 2 Aug to 3 Aug
฿4,246
฿4,880 total
2 Aug - 3 Aug
includes taxes & fees
Stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful staff ...
8/10 Very good! (2,797 reviews)
"Free breakfast included!"
Reviewed on 9 Jul 2026
Bahia Resort Hotel
998 W Mission Bay Dr San Diego CA
The price is ฿8,682 per night from 9 Aug to 10 Aug
฿8,682
฿11,829 total
9 Aug - 10 Aug
includes taxes & fees
Stay at this beach resort in San Diego. Enjoy a beach locale, breakfast (surcharge) and 24-hour room service. Our guests praise the pool and the restaurant in ...
8.8/10 Excellent! (2,235 reviews)
"Beautiful landscaped well kept grounds. The rooms were a bit outdated and not super clean. We brought our concern to the front desk staff and they sent housekeeping to clean the room. The gorgeous grounds, pool, beachy area, pickle ball courts, little kids park and daily activities were enough to ..."
Reviewed on 9 Jul 2026
Bay Club Hotel & Marina
2131 Shelter Island Dr San Diego CA
The price is ฿6,921 per night from 10 Aug to 11 Aug
฿6,921
฿7,956 total
10 Aug - 11 Aug
includes taxes & fees
Stay at this business-friendly hotel in San Diego. Enjoy free Wi-Fi, a marina and a health club. Our guests praise the breakfast and the restaurant in their ...
9.2/10 Wonderful! (3,738 reviews)
"Truly enjoyed our stay here in San Diego! The staff is super friendly and helpful! Room was super comfortable and the restaurant was top notch!"
Reviewed on 10 Jul 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Otay Mesa
Find the best Otay Mesa areas for the activities you enjoy most.
Downtown San Diego
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Seaport Village are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
Pacific Beach
The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Pacific Beach while you're exploring the area.
Mission Beach
If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.
Gaslamp Quarter
Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Spreckels Theater – discover Gaslamp Quarter, a destination also famous for its shopping.
Mission Bay
If you're spending some time in Mission Bay, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.
