Search Hotels in Otay Mesa, San Diego
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Our top choices for Otay Mesa hotels
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHGOtay Mesa
8.0 out of 10, Very good, (1,590 reviews)
"Great place to stay. Really clean and helpful staff "
Zulma
The price is ฿3,743
฿4,258 total
includes taxes & fees
18 Jan - 19 Jan
Quality Suites San Diego Otay Mesa
Quality Suites San Diego Otay MesaOtay Mesa
7.0 out of 10, Good, (1,001 reviews)
"Clean, convenient location "
Mary
The price is ฿3,114
฿3,542 total
includes taxes & fees
18 Jan - 19 Jan
Sycuan Casino Resort
Sycuan Casino Resort28.5 km from Otay Mesa
9.2 out of 10, Wonderful, (1,672 reviews)
"Very clean resort. "
Petrina
Hotel Palmeras Chula Vista
Hotel Palmeras Chula Vista14.4 km from Otay Mesa
7.2 out of 10, Good, (2,054 reviews)
"Great stay"
Bobby
The price is ฿1,839
฿2,023 total
includes taxes & fees
25 Jan - 26 Jan
Wyndham Garden San Diego Near SeaWorld
Wyndham Garden San Diego Near SeaWorld31.3 km from Otay Mesa
7.4 out of 10, Good, (4,134 reviews)
"Get location to the airport, safe, great staff, & overall wonderful stay"
Tyler
The price is ฿2,655
฿3,052 total
includes taxes & fees
27 Jan - 28 Jan
Kings Inn San Diego
Kings Inn San Diego29.1 km from Otay Mesa
8.8 out of 10, Excellent, (3,607 reviews)
"Good location, friendly staff"
Natalia
Crowne Plaza San Diego - Mission Valley by IHG
Crowne Plaza San Diego - Mission Valley by IHG29.8 km from Otay Mesa
7.8 out of 10, Good, (1,003 reviews)
"Great stay"
Viviann
The price is ฿3,051
฿3,520 total
includes taxes & fees
25 Jan - 26 Jan
Comfort Inn San Diego Old Town
Comfort Inn San Diego Old TownOld Town San Diego, 29.6 km from Otay Mesa
8.2 out of 10, Very good, (1,935 reviews)
"Great stay "
Vanessa
The price is ฿2,660
฿3,057 total
includes taxes & fees
25 Jan - 26 Jan
La Quinta Inn by Wyndham San Diego Chula Vista
La Quinta Inn by Wyndham San Diego Chula Vista12.9 km from Otay Mesa
8.6 out of 10, Excellent, (1,510 reviews)
"Everything was great, staff , Room , clean , great place to stay "
Luis
The price is ฿3,075
฿3,382 total
includes taxes & fees
1 Feb - 2 Feb
Best Western Yacht Harbor Hotel
Best Western Yacht Harbor Hotel29.9 km from Otay Mesa
8.6 out of 10, Excellent, (1,677 reviews)
"Great rate for a great stay!"
James
The price is ฿3,517
฿4,036 total
includes taxes & fees
26 Jan - 27 Jan
San Diego Mission Bay Resort
San Diego Mission Bay ResortMission Bay, 33.1 km from Otay Mesa
8.4 out of 10, Very good, (1,337 reviews)
"Great place for our family getaway! Loved the S’mores on the beach! "
Dani
The price is ฿4,784
฿7,163 total
includes taxes & fees
2 Feb - 3 Feb
Hyatt Regency Mission Bay Spa and Marina
Hyatt Regency Mission Bay Spa and MarinaMission Bay, 33.9 km from Otay Mesa
8.4 out of 10, Very good, (1,586 reviews)
"Beautiful grounds with lots of activities for all ages."
Brandon
The price is ฿4,372
฿6,690 total
includes taxes & fees
18 Jan - 19 Jan
Ocean Villa Inn
Ocean Villa InnOcean Beach, 33.7 km from Otay Mesa
8.0 out of 10, Very good, (1,150 reviews)
"It’s good place for the value "
Marcin
Loews Coronado Bay Resort
Loews Coronado Bay Resort17.2 km from Otay Mesa
8.8 out of 10, Excellent, (1,064 reviews)
"The staff and amenities were spectacular. "
Andrew
The price is ฿5,945
฿8,130 total
includes taxes & fees
8 Feb - 9 Feb
Westgate Hotel
Westgate Hotel24.9 km from Otay Mesa
9.0 out of 10, Wonderful, (1,005 reviews)
"The hotel was a great stay. Beautiful lobby, large room and such a comfortable bed."
Victor
Hampton Inn San Diego/Mission Valley
Hampton Inn San Diego/Mission Valley29.6 km from Otay Mesa
8.6 out of 10, Excellent, (1,366 reviews)
"Great breakfast-comfortable rooms-helpful staff-great location for events"
bill
The price is ฿3,029
฿3,482 total
includes taxes & fees
25 Jan - 26 Jan
The Rambler
The Rambler14.8 km from Otay Mesa
9.2 out of 10, Wonderful, (2,034 reviews)
"Absolutely amazing stay will def be coming back!"
Victor
The price is ฿3,423
฿3,960 total
includes taxes & fees
28 Jan - 29 Jan
Staypineapple, Hotel Z, Gaslamp San Diego
Staypineapple, Hotel Z, Gaslamp San DiegoGaslamp Quarter, 24.2 km from Otay Mesa
9.4 out of 10, Exceptional, (1,009 reviews)
"Outstanding hotel"
Lee
The price is ฿2,800
฿4,155 total
includes taxes & fees
25 Jan - 26 Jan
Best Western Seven Seas
Best Western Seven Seas28.7 km from Otay Mesa
8.0 out of 10, Very good, (3,128 reviews)
"Breakfast was good and the staff was friendly and excellent. "
Thuan
The price is ฿2,208
฿2,538 total
includes taxes & fees
25 Jan - 26 Jan
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Otay Mesa
Find the best Otay Mesa areas for the activities you enjoy most.
Downtown San Diego
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
Gaslamp Quarter
San Diego’s historic heart has shed its seedy past to emerge as one of the city’s premier dining, shopping and entertainment hubs.
Pacific Beach
Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.
Mission Beach
If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.
Ocean Beach
Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Dog Beach and Ocean Beach Farmers Market.
