Search Hotels in Otay Mesa, San Diego
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Our top choices for Otay Mesa hotels
Quality Suites San Diego Otay Mesa
Quality Suites San Diego Otay MesaOtay Mesa
7.0 out of 10, Good, (1,003 reviews)
"Great staff.. location close to the airport!"
Vivian
The price is ฿3,399
฿3,866 total
includes taxes & fees
5 Apr - 6 Apr
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHGOtay Mesa
8.0 out of 10, Very good, (1,661 reviews)
"Clean, great breakfast, good service."
Sara
The price is ฿4,075
฿4,635 total
includes taxes & fees
8 Mar - 9 Mar
Crowne Plaza San Diego - Mission Valley by IHG
Crowne Plaza San Diego - Mission Valley by IHG29.8 km from Otay Mesa
8.0 out of 10, Very good, (1,012 reviews)
"Great stay"
Viviann
The price is ฿3,190
฿3,680 total
includes taxes & fees
8 Mar - 9 Mar
Sheraton San Diego Resort
Sheraton San Diego Resort28.1 km from Otay Mesa
8.4 out of 10, Very good, (3,361 reviews)
"Love this hotel will always stay here when I come to San Diego "
Darlene
The price is ฿3,949
฿5,929 total
includes taxes & fees
3 Apr - 4 Apr
Lafayette Hotel & Club
Lafayette Hotel & Club26.8 km from Otay Mesa
9.2 out of 10, Wonderful, (1,504 reviews)
"Stunning hotel, I could have stayed there all day looking at every little design detail. "
Holly
The price is ฿7,234
฿8,301 total
includes taxes & fees
9 Mar - 10 Mar
Sycuan Casino Resort
Sycuan Casino Resort28.5 km from Otay Mesa
9.2 out of 10, Wonderful, (1,780 reviews)
"Very clean resort. "
Petrina
Valli Hi Motel
Valli Hi Motel7.9 km from Otay Mesa
8.4 out of 10, Very good, (1,006 reviews)
"Excelente "
Julio
Best Western Chula Vista/Otay Valley Hotel
Best Western Chula Vista/Otay Valley Hotel7.1 km from Otay Mesa
7.8 out of 10, Good, (1,633 reviews)
"Clean rooms and the breakfast was amazing "
Vanessa
The price is ฿3,260
฿3,586 total
includes taxes & fees
8 Mar - 9 Mar
SpringHill Suites by Marriott Chula Vista Eastlake
SpringHill Suites by Marriott Chula Vista Eastlake10.5 km from Otay Mesa
9.6 out of 10, Exceptional, (586 reviews)
"Clean room and friendly staff "
Michael
The price is ฿5,402
฿5,952 total
includes taxes & fees
22 Mar - 23 Mar
Motel 6 El Cajon, CA - San Diego
Motel 6 El Cajon, CA - San Diego27 km from Otay Mesa
7.4 out of 10, Good, (1,567 reviews)
"We only stayed one night but it was comfortable and clean "
Brandy
The price is ฿2,066
฿2,277 total
includes taxes & fees
20 Mar - 21 Mar
Wyndham Garden San Diego Near SeaWorld
Wyndham Garden San Diego Near SeaWorld31.3 km from Otay Mesa
7.4 out of 10, Good, (4,185 reviews)
"Good location friendly staff"
Anya
The price is ฿2,971
฿3,415 total
includes taxes & fees
12 Mar - 13 Mar
Ocean Villa Inn
Ocean Villa InnOcean Beach, 33.7 km from Otay Mesa
8.0 out of 10, Very good, (1,191 reviews)
"Beds are super comfy clean and renovated"
Esmeralda
Best Western San Diego Pacific Beach/Mission Bay
Best Western San Diego Pacific Beach/Mission Bay33.6 km from Otay Mesa
8.2 out of 10, Very good, (290 reviews)
"Clean hotel & great location. "
yardley
The price is ฿3,209
฿3,689 total
includes taxes & fees
8 Mar - 9 Mar
Comfort Inn Sea World Area
Comfort Inn Sea World Area30.8 km from Otay Mesa
8.6 out of 10, Excellent, (3,443 reviews)
"Nice beds and breakfast, really convenient "
Margarita
The price is ฿3,088
฿3,549 total
includes taxes & fees
12 Mar - 13 Mar
Loews Coronado Bay Resort
Loews Coronado Bay Resort17.2 km from Otay Mesa
8.8 out of 10, Excellent, (1,078 reviews)
"Clean room, gorgeous grounds, very friendly staff "
Taryn
The price is ฿7,234
฿9,584 total
includes taxes & fees
5 Apr - 6 Apr
La Quinta Inn by Wyndham San Diego Chula Vista
La Quinta Inn by Wyndham San Diego Chula Vista12.9 km from Otay Mesa
8.6 out of 10, Excellent, (1,553 reviews)
"The room was very clean and the staff was very nice."
Rod
The price is ฿3,142
฿3,456 total
includes taxes & fees
15 Mar - 16 Mar
Best Western Americana Inn
Best Western Americana Inn8 km from Otay Mesa
9.0 out of 10, Wonderful, (1,219 reviews)
"Great stay"
Elisa
The price is ฿3,732
฿4,245 total
includes taxes & fees
17 Mar - 18 Mar
Best Western Plus Marina Gateway Hotel
Best Western Plus Marina Gateway Hotel16.9 km from Otay Mesa
9.2 out of 10, Wonderful, (3,755 reviews)
"My favorite place to stay"
Rubidia
The price is ฿4,018
฿4,428 total
includes taxes & fees
8 Mar - 9 Mar
Hampton Inn & Suites by Hilton San Diego SeaWorld Near Old Town
Hampton Inn & Suites by Hilton San Diego SeaWorld Near Old Town30.8 km from Otay Mesa
9.2 out of 10, Wonderful, (695 reviews)
"Great place to stay, nice room Highly recommended !!"
Wilfredo
The price is ฿5,202
฿5,980 total
includes taxes & fees
8 Mar - 9 Mar
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Otay Mesa
Find the best Otay Mesa areas for the activities you enjoy most.
Downtown San Diego
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
Pacific Beach
Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.
Mission Beach
If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.
Gaslamp Quarter
San Diego’s historic heart has shed its seedy past to emerge as one of the city’s premier dining, shopping and entertainment hubs.
Ocean Beach
Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Ocean Beach and Dog Beach.
