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Our top choices for Otay Mesa hotels

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Quality Suites San Diego Otay Mesa
Quality Suites San Diego Otay Mesa
Sycuan Casino Resort
Sycuan Casino Resort
Hotel Palmeras Chula Vista
Hotel Palmeras Chula Vista
Wyndham Garden San Diego Near SeaWorld
Wyndham Garden San Diego Near SeaWorld
Kings Inn San Diego
Kings Inn San Diego
Crowne Plaza San Diego - Mission Valley by IHG
Crowne Plaza San Diego - Mission Valley by IHG
Comfort Inn San Diego Old Town
Comfort Inn San Diego Old Town
La Quinta Inn by Wyndham San Diego Chula Vista
La Quinta Inn by Wyndham San Diego Chula Vista
Best Western Yacht Harbor Hotel
Best Western Yacht Harbor Hotel
San Diego Mission Bay Resort
San Diego Mission Bay Resort
Hyatt Regency Mission Bay Spa and Marina
Hyatt Regency Mission Bay Spa and Marina
Ocean Villa Inn
Ocean Villa Inn
Loews Coronado Bay Resort
Loews Coronado Bay Resort
Hampton Inn San Diego/Mission Valley
Hampton Inn San Diego/Mission Valley
The Rambler
The Rambler
Staypineapple, Hotel Z, Gaslamp San Diego
Staypineapple, Hotel Z, Gaslamp San Diego
Best Western Seven Seas
Best Western Seven SeasWhere to stay in Otay Mesa

Downtown San Diego
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Gaslamp Quarter
San Diego’s historic heart has shed its seedy past to emerge as one of the city’s premier dining, shopping and entertainment hubs.

Pacific Beach
Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

Mission Beach
If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Ocean Beach
Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Dog Beach and Ocean Beach Farmers Market.
























































































