Search Hotels in Otay Mesa, San Diego
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Our top choices for Otay Mesa hotels
Quality Suites San Diego Otay Mesa
Quality Suites San Diego Otay MesaOtay Mesa
7.2 out of 10, Good, (1,009 reviews)
"Very clean, bed was comfortable!"
Michael A
The price is ฿3,727
฿4,239 total
includes taxes & fees
28 Jun - 29 Jun
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHGOtay Mesa
8.2 out of 10, Very good, (1,763 reviews)
"Clean, friendly staff, great breakfast!!"
Flor
The price is ฿4,780
฿5,437 total
includes taxes & fees
5 Jul - 6 Jul
Crowne Plaza San Diego - Mission Valley by IHG
Crowne Plaza San Diego - Mission Valley by IHG29.8 km from Otay Mesa
8.4 out of 10, Very good, (1,018 reviews)
"great stay"
David
The price is ฿3,890
฿4,483 total
includes taxes & fees
29 Jun - 30 Jun
Valli Hi Motel
Valli Hi Motel7.9 km from Otay Mesa
8.4 out of 10, Very good, (1,020 reviews)
"Great place to stay."
Allan
The price is ฿2,967
฿3,381 total
includes taxes & fees
23 Jun - 24 Jun
Sheraton San Diego Resort
Sheraton San Diego Resort28.1 km from Otay Mesa
8.4 out of 10, Very good, (3,543 reviews)
"Great location and shuttle service to and from the airport."
Malinda
The price is ฿5,248
฿7,700 total
includes taxes & fees
1 Jul - 2 Jul
Sycuan Casino Resort
Sycuan Casino Resort28.5 km from Otay Mesa
9.4 out of 10, Exceptional, (1,987 reviews)
"Always a great stay"
Jeanette
The price is ฿3,811
฿4,587 total
includes taxes & fees
12 Jul - 13 Jul
Motel 6 El Cajon, CA - San Diego
Motel 6 El Cajon, CA - San Diego27 km from Otay Mesa
7.4 out of 10, Good, (1,694 reviews)
"A good place to stay if you need a place to crash in for the night"
Ivy Ruth
The price is ฿2,838
฿3,127 total
includes taxes & fees
23 Jun - 24 Jun
Studio 6 Suites San Ysidro, CA -San Diego South Bay
Studio 6 Suites San Ysidro, CA -San Diego South Bay6.9 km from Otay Mesa
8.0 out of 10, Very good, (1,691 reviews)
"It’s ok to stay one or two days"
Valentina
The price is ฿2,604
฿2,967 total
includes taxes & fees
23 Jun - 24 Jun
Lafayette Hotel & Club
Lafayette Hotel & Club26.8 km from Otay Mesa
9.4 out of 10, Exceptional, (1,740 reviews)
"Beautiful hotel"
Cuauhtemoc
The price is ฿8,208
฿9,435 total
includes taxes & fees
29 Jun - 30 Jun
Ocean Villa Inn
Ocean Villa InnOcean Beach, 33.7 km from Otay Mesa
8.0 out of 10, Very good, (1,300 reviews)
"This is very pet friendly and staff is great"
Arturo
The price is ฿6,791
฿7,657 total
includes taxes & fees
28 Jun - 29 Jun
Wyndham Garden San Diego Near SeaWorld
Wyndham Garden San Diego Near SeaWorld31.3 km from Otay Mesa
7.4 out of 10, Good, (4,198 reviews)
"Clean room, staff was very helpful, parking was easy and accessible!"
Hector
The price is ฿4,252
฿4,888 total
includes taxes & fees
1 Jul - 2 Jul
Best Western Chula Vista/Otay Valley Hotel
Best Western Chula Vista/Otay Valley Hotel7.1 km from Otay Mesa
8.0 out of 10, Very good, (1,813 reviews)
"The stay was great, and breakfast was delicious"
Katie
The price is ฿3,895
฿4,292 total
includes taxes & fees
5 Jul - 6 Jul
SpringHill Suites by Marriott Chula Vista Eastlake
SpringHill Suites by Marriott Chula Vista Eastlake10.5 km from Otay Mesa
9.6 out of 10, Exceptional, (674 reviews)
"It was great, one of the best stays we have had while traveling this year!"
Ken
The price is ฿7,910
฿8,716 total
includes taxes & fees
20 Jul - 21 Jul
Best Western San Diego Pacific Beach/Mission Bay
Best Western San Diego Pacific Beach/Mission BayBay Park, 33.6 km from Otay Mesa
8.2 out of 10, Very good, (434 reviews)
"Nice hotel."
Aron
The price is ฿4,612
฿5,302 total
includes taxes & fees
28 Jun - 29 Jun
Holiday Inn Express San Diego Airport - Old Town by IHG
Holiday Inn Express San Diego Airport - Old Town by IHG28.8 km from Otay Mesa
9.2 out of 10, Wonderful, (1,083 reviews)
"Staff was so great nice rooms really great stay"
Amelia
The price is ฿5,340
฿6,138 total
includes taxes & fees
30 Jun - 1 Jul
Heritage Inn San Diego
Heritage Inn San Diego31.8 km from Otay Mesa
7.2 out of 10, Good, (1,548 reviews)
"Great stay"
Alyssa
The price is ฿2,388
฿2,745 total
includes taxes & fees
28 Jun - 29 Jun
Old Town Inn
Old Town Inn30.1 km from Otay Mesa
9.2 out of 10, Wonderful, (1,880 reviews)
"Clean room, good breakfast, comfortable pool area, friendly staff."
Robert
The price is ฿5,506
฿6,318 total
includes taxes & fees
29 Jun - 30 Jun
Ocean Beach Hotel
Ocean Beach HotelOcean Beach, 33.5 km from Otay Mesa
8.8 out of 10, Excellent, (1,377 reviews)
"Great view of the beach and pier from our room and balcony."
Donovan
The price is ฿7,684
฿8,664 total
includes taxes & fees
30 Jun - 1 Jul
Comfort Inn Sea World Area
Comfort Inn Sea World Area30.8 km from Otay Mesa
8.6 out of 10, Excellent, (3,799 reviews)
"Nice staff and good breakfast"
Fernando
The price is ฿4,391
฿5,047 total
includes taxes & fees
29 Jun - 30 Jun
Days Inn by Wyndham San Diego-East/El Cajon
Days Inn by Wyndham San Diego-East/El Cajon27.3 km from Otay Mesa
7.8 out of 10, Good, (1,008 reviews)
"Rooms were cheap clean property was clean convenient close to where I was working"
James
The price is ฿3,334
฿3,675 total
includes taxes & fees
28 Jun - 29 Jun
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Otay Mesa
Find the best Otay Mesa areas for the activities you enjoy most.
Downtown San Diego
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
Pacific Beach
Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.
Mission Beach
If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.
Gaslamp Quarter
San Diego’s historic heart has shed its seedy past to emerge as one of the city’s premier dining, shopping and entertainment hubs.
Mission Bay
If you're spending some time in Mission Bay, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.
Top Otay Mesa Hotel Reviews
Hotel del Coronado, Curio Collection by Hilton
10/10 Excellent
