Search Hotels in Otay Mesa, San Diego
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Our top choices for Otay Mesa hotels
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHGOtay Mesa
8.2 out of 10, Very good, (1,723 reviews)
"Very clean. Staff was very friendly. Breakfast buffet was very complete and with variety of food."
Eliza
The price is ฿4,047
฿4,604 total
includes taxes & fees
31 May - 1 Jun
Quality Suites San Diego Otay Mesa
Quality Suites San Diego Otay MesaOtay Mesa
7.0 out of 10, Good, (1,004 reviews)
"The only hotel in otay mesa and overall the service was good"
MARIA
The price is ฿3,141
฿3,573 total
includes taxes & fees
31 May - 1 Jun
Best Western Yacht Harbor Hotel
Best Western Yacht Harbor Hotel29.9 km from Otay Mesa
8.4 out of 10, Very good, (1,855 reviews)
"Staff are great. Awesome location. Good breakfast, heated pool. Would stay again!"
Kent
The price is ฿3,106
฿3,564 total
includes taxes & fees
4 May - 5 May
Hampton Inn & Suites Imperial Beach San Diego
Hampton Inn & Suites Imperial Beach San Diego13.7 km from Otay Mesa
9.4 out of 10, Exceptional, (1,001 reviews)
"Room was great, very clean. Staff was so friendly and helpful. Other visitors were great conversation over breakfast. Tons of places to eat walking distance and super close to the beach. For the price it was incredible. Will be returning soon. "
Isabel
The price is ฿4,376
฿4,997 total
includes taxes & fees
10 May - 11 May
Sheraton San Diego Resort
Sheraton San Diego Resort28.1 km from Otay Mesa
8.4 out of 10, Very good, (3,510 reviews)
"The restaurants were amazing. Food was delicious and fresh. The pool was spacious and loved the poolside service. Plenty of seating options. The beds were very comfortable. Great airport shuttle. Loved the location. Close to harbor walk."
Helene
The price is ฿5,472
฿7,928 total
includes taxes & fees
25 May - 26 May
Sycuan Casino Resort
Sycuan Casino Resort28.5 km from Otay Mesa
9.4 out of 10, Exceptional, (1,888 reviews)
"This is a great hotel and casino. Very fun and clean atmosphere. No need to venture out for food Restaurants are great!!"
Frances
The price is ฿3,193
฿3,900 total
includes taxes & fees
4 May - 5 May
Best Western San Diego Pacific Beach/Mission Bay
Best Western San Diego Pacific Beach/Mission BayBay Park, 33.6 km from Otay Mesa
8.2 out of 10, Very good, (376 reviews)
"Great room. Staff was friendly. Easy access to trolley and free parking made getting around super easy. "
Jason
The price is ฿2,821
฿3,242 total
includes taxes & fees
10 May - 11 May
Motel 6 El Cajon, CA - San Diego
Motel 6 El Cajon, CA - San Diego27 km from Otay Mesa
7.4 out of 10, Good, (1,658 reviews)
"The staff is always polite. Always friendly and welcoming. Way different place to visit then it was years ago. It's clean and pleasant. "
wes
The price is ฿2,532
฿2,790 total
includes taxes & fees
17 May - 18 May
Holiday Inn Express San Diego Airport - Old Town by IHG
Holiday Inn Express San Diego Airport - Old Town by IHG28.8 km from Otay Mesa
9.2 out of 10, Wonderful, (1,057 reviews)
"Staff was great- very helpful!!"
Jeffrey
The price is ฿4,565
฿5,248 total
includes taxes & fees
6 May - 7 May
SpringHill Suites by Marriott Chula Vista Eastlake
SpringHill Suites by Marriott Chula Vista Eastlake10.5 km from Otay Mesa
9.6 out of 10, Exceptional, (639 reviews)
"Clean and spacious room. Amazing outdoor pool/jacuzzi with outdoor seating and a nice fire pit. The bartender Mico is THEE BEST! "
Shatera
The price is ฿6,379
฿7,029 total
includes taxes & fees
14 May - 15 May
Ocean Villa Inn
Ocean Villa InnOcean Beach, 33.7 km from Otay Mesa
8.0 out of 10, Very good, (1,262 reviews)
"Basic beach motel. Served its purpose. Its old and dingy but it was quiet and safe. Manager was very nice. "
Karin
The price is ฿3,646
฿4,110 total
includes taxes & fees
5 May - 6 May
Lafayette Hotel & Club
Lafayette Hotel & Club26.8 km from Otay Mesa
9.4 out of 10, Exceptional, (1,625 reviews)
"I loved this hotel. It was absolutely my type the staff was lovely and I would go back."
Evelyn
The price is ฿8,062
฿9,267 total
includes taxes & fees
5 May - 6 May
Studio 6 Suites San Ysidro, CA -San Diego South Bay
Studio 6 Suites San Ysidro, CA -San Diego South Bay6.9 km from Otay Mesa
8.0 out of 10, Very good, (1,632 reviews)
"The price was cheaper on Expedia than walking in. The staff was nice. The room was clean. More than enough room for parking. I would get a room there again."
Hanna
The price is ฿2,590
฿2,951 total
includes taxes & fees
4 May - 5 May
Best Western Plus Marina Gateway Hotel
Best Western Plus Marina Gateway Hotel16.9 km from Otay Mesa
9.2 out of 10, Wonderful, (3,799 reviews)
"Nice property. Had a good restaurant adjacent. "
Mr. or Ms.
The price is ฿4,634
฿5,106 total
includes taxes & fees
10 May - 11 May
Wyndham Garden San Diego Near SeaWorld
Wyndham Garden San Diego Near SeaWorld31.3 km from Otay Mesa
7.4 out of 10, Good, (4,220 reviews)
"Over all great stay. Close to the arena which is the best perk! Over all clean and safe. On site security. Shopping and food near by."
Kevin
The price is ฿3,529
฿4,057 total
includes taxes & fees
4 May - 5 May
Days Inn by Wyndham San Diego-East/El Cajon
Days Inn by Wyndham San Diego-East/El Cajon27.3 km from Otay Mesa
7.8 out of 10, Good, (1,005 reviews)
"My room was perfect in every way. The complimentary breakfast was excellent, plenty of variety and quantity with nice seating.
Day’s Inn has a great location for traveling on foot, bus or trolley to many locations.
I will stay here again on my next trip. "
Marla
The price is ฿2,862
฿3,154 total
includes taxes & fees
5 May - 6 May
Bay Club Hotel & Marina
Bay Club Hotel & Marina29.2 km from Otay Mesa
9.2 out of 10, Wonderful, (3,561 reviews)
"Room was very clean, staff was friendly and location was amazing!!"
Erica
The price is ฿4,926
฿5,663 total
includes taxes & fees
12 May - 13 May
San Diego Mission Bay Resort
San Diego Mission Bay ResortMission Bay, 33.1 km from Otay Mesa
8.4 out of 10, Very good, (1,435 reviews)
"Nice and clean. Easy. Thanks. "
Nancy
The price is ฿7,091
฿9,863 total
includes taxes & fees
10 May - 11 May
Holiday Inn Express San Diego South - Chula Vista by IHG
Holiday Inn Express San Diego South - Chula Vista by IHG14.5 km from Otay Mesa
9.4 out of 10, Exceptional, (1,121 reviews)
"Location was fairly convenient to most attractions. The staff was awesome. Breakfast was good. The fact that we didn't have to pay for parking was one of the reasons we chose this hotel compared to others in the San Diego area."
Melissa
The price is ฿4,101
฿4,511 total
includes taxes & fees
25 May - 26 May
Best Western Americana Inn
Best Western Americana Inn8 km from Otay Mesa
9.0 out of 10, Wonderful, (1,266 reviews)
"Nice hotel close to Mexican border. Continental breakfast included. "
Martina
The price is ฿3,961
฿4,505 total
includes taxes & fees
10 May - 11 May
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Otay Mesa
Find the best Otay Mesa areas for the activities you enjoy most.
Downtown San Diego
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
Pacific Beach
Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.
Mission Beach
If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.
Gaslamp Quarter
San Diego’s historic heart has shed its seedy past to emerge as one of the city’s premier dining, shopping and entertainment hubs.
Ocean Beach
Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Dog Beach and Ocean Beach Farmers Market.
