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Our top choices for Otay Mesa hotels

Quality Suites San Diego Otay Mesa

Quality Suites San Diego Otay Mesa
2.5 star property
Otay Mesa
7.0 out of 10, Good, (1,003 reviews)
"Great staff.. location close to the airport!"
United States
Vivian
The price is ฿3,399
฿3,866 total
includes taxes & fees
5 Apr - 6 Apr
Quality Suites San Diego Otay Mesa

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
2.5 star property
Otay Mesa
8.0 out of 10, Very good, (1,661 reviews)
"Clean, great breakfast, good service."
United States
Sara
The price is ฿4,075
฿4,635 total
includes taxes & fees
8 Mar - 9 Mar
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Crowne Plaza San Diego - Mission Valley by IHG

Crowne Plaza San Diego - Mission Valley by IHG
3.5 star property
29.8 km from Otay Mesa
8.0 out of 10, Very good, (1,012 reviews)
"Great stay"
United States
Viviann
The price is ฿3,190
฿3,680 total
includes taxes & fees
8 Mar - 9 Mar
Crowne Plaza San Diego - Mission Valley by IHG

Sheraton San Diego Resort

Sheraton San Diego Resort
4.0 star property
28.1 km from Otay Mesa
8.4 out of 10, Very good, (3,361 reviews)
"Love this hotel will always stay here when I come to San Diego "
United States
Darlene
The price is ฿3,949
฿5,929 total
includes taxes & fees
3 Apr - 4 Apr
Sheraton San Diego Resort

Lafayette Hotel & Club

Lafayette Hotel & Club
4.0 star property
26.8 km from Otay Mesa
9.2 out of 10, Wonderful, (1,504 reviews)
"Stunning hotel, I could have stayed there all day looking at every little design detail. "
United States
Holly
The price is ฿7,234
฿8,301 total
includes taxes & fees
9 Mar - 10 Mar
Lafayette Hotel & Club

Sycuan Casino Resort

Sycuan Casino Resort
4.0 star property
28.5 km from Otay Mesa
9.2 out of 10, Wonderful, (1,780 reviews)
"Very clean resort. "
United States
Petrina
Sycuan Casino Resort

Valli Hi Motel

Valli Hi Motel
2.5 star property
7.9 km from Otay Mesa
8.4 out of 10, Very good, (1,006 reviews)
"Excelente "
Mexico
Julio
Valli Hi Motel

Best Western Chula Vista/Otay Valley Hotel

Best Western Chula Vista/Otay Valley Hotel
2.5 star property
7.1 km from Otay Mesa
7.8 out of 10, Good, (1,633 reviews)
"Clean rooms and the breakfast was amazing "
United States
Vanessa
The price is ฿3,260
฿3,586 total
includes taxes & fees
8 Mar - 9 Mar
Best Western Chula Vista/Otay Valley Hotel

SpringHill Suites by Marriott Chula Vista Eastlake

SpringHill Suites by Marriott Chula Vista Eastlake
3.5 star property
10.5 km from Otay Mesa
9.6 out of 10, Exceptional, (586 reviews)
"Clean room and friendly staff "
United States
Michael
The price is ฿5,402
฿5,952 total
includes taxes & fees
22 Mar - 23 Mar
SpringHill Suites by Marriott Chula Vista Eastlake

Motel 6 El Cajon, CA - San Diego

Motel 6 El Cajon, CA - San Diego
2.0 star property
27 km from Otay Mesa
7.4 out of 10, Good, (1,567 reviews)
"We only stayed one night but it was comfortable and clean "
United States
Brandy
The price is ฿2,066
฿2,277 total
includes taxes & fees
20 Mar - 21 Mar
Motel 6 El Cajon, CA - San Diego

Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld
3.0 star property
31.3 km from Otay Mesa
7.4 out of 10, Good, (4,185 reviews)
"Good location friendly staff"
United States
Anya
The price is ฿2,971
฿3,415 total
includes taxes & fees
12 Mar - 13 Mar
Wyndham Garden San Diego Near SeaWorld

Ocean Villa Inn

Ocean Villa Inn
2.5 star property
Ocean Beach, 33.7 km from Otay Mesa
8.0 out of 10, Very good, (1,191 reviews)
"Beds are super comfy clean and renovated"
United States
Esmeralda
Ocean Villa Inn

Best Western San Diego Pacific Beach/Mission Bay

Best Western San Diego Pacific Beach/Mission Bay
2.5 star property
33.6 km from Otay Mesa
8.2 out of 10, Very good, (290 reviews)
"Clean hotel & great location. "
United States
yardley
The price is ฿3,209
฿3,689 total
includes taxes & fees
8 Mar - 9 Mar
Best Western San Diego Pacific Beach/Mission Bay

Comfort Inn Sea World Area

Comfort Inn Sea World Area
3.5 star property
30.8 km from Otay Mesa
8.6 out of 10, Excellent, (3,443 reviews)
"Nice beds and breakfast, really convenient "
Canada
Margarita
The price is ฿3,088
฿3,549 total
includes taxes & fees
12 Mar - 13 Mar
Comfort Inn Sea World Area

Ash&9th

Ash&9th
2.0 star property
24.7 km from Otay Mesa
8.2 out of 10, Very good, (388 reviews)
"Great location… stuff was really friendly "
United States
Aurora
The price is ฿2,559
฿2,911 total
includes taxes & fees
6 Apr - 7 Apr
Ash&9th

Loews Coronado Bay Resort

Loews Coronado Bay Resort
4.0 star property
17.2 km from Otay Mesa
8.8 out of 10, Excellent, (1,078 reviews)
"Clean room, gorgeous grounds, very friendly staff "
United States
Taryn
The price is ฿7,234
฿9,584 total
includes taxes & fees
5 Apr - 6 Apr
Loews Coronado Bay Resort

La Quinta Inn by Wyndham San Diego Chula Vista

La Quinta Inn by Wyndham San Diego Chula Vista
3.0 star property
12.9 km from Otay Mesa
8.6 out of 10, Excellent, (1,553 reviews)
"The room was very clean and the staff was very nice."
United States
Rod
The price is ฿3,142
฿3,456 total
includes taxes & fees
15 Mar - 16 Mar
La Quinta Inn by Wyndham San Diego Chula Vista

Best Western Americana Inn

Best Western Americana Inn
2.5 star property
8 km from Otay Mesa
9.0 out of 10, Wonderful, (1,219 reviews)
"Great stay"
United States
Elisa
The price is ฿3,732
฿4,245 total
includes taxes & fees
17 Mar - 18 Mar
Best Western Americana Inn

Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel
3.5 star property
16.9 km from Otay Mesa
9.2 out of 10, Wonderful, (3,755 reviews)
"My favorite place to stay"
United States
Rubidia
The price is ฿4,018
฿4,428 total
includes taxes & fees
8 Mar - 9 Mar
Best Western Plus Marina Gateway Hotel

Hampton Inn & Suites by Hilton San Diego SeaWorld Near Old Town

Hampton Inn & Suites by Hilton San Diego SeaWorld Near Old Town
3.0 star property
30.8 km from Otay Mesa
9.2 out of 10, Wonderful, (694 reviews)
"Great place to stay, nice room Highly recommended !!"
United States
Wilfredo
The price is ฿5,202
฿5,980 total
includes taxes & fees
8 Mar - 9 Mar
Hampton Inn & Suites by Hilton San Diego SeaWorld Near Old Town
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Otay Mesa

Find the best Otay Mesa areas for the activities you enjoy most.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Gaslamp Quarter

San Diego’s historic heart has shed its seedy past to emerge as one of the city’s premier dining, shopping and entertainment hubs.

Ocean Beach

Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Ocean Beach and Dog Beach.

Top Otay Mesa Hotel Reviews

Frequently asked questions

What's it like in Otay Mesa?
Otay Mesa is a neighbourhood that travellers like for its beaches, restaurants and shopping.
Where is the best hotel for a stay in Otay Mesa?
Based on Expedia customer reviews, Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG is the highest ranked property in Otay Mesa. This hotel offers free breakfast and an outdoor pool. Another top choice in the area is Quality Suites San Diego Otay Mesa.
If I need to cancel my hotel reservation in Otay Mesa, will I receive a refund?
Yes! Most room reservations are refundable provided that you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Add dates, click "Search", then filter by "fully refundable" to view top deals in Otay Mesa.
What is there to do in this San Diego neighbourhood?
A few places to visit in the area around Otay Mesa include High Performance Center in Tijuana, Parque Industrial FINSA Tijuana and Otay Sports Fields. While you're out sightseeing, Caliente Casino and Alameda Otay are a couple of additional sights to visit in San Diego.

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