Otay Mesa Travel Guide
San Diego
Visit Otay Mesa
Stay near popular Otay Mesa attractions
Things to do
Tour of San Diego>Rosarito >Giant Christ>Puerto Nuevo Lobster
Tijuana Downtown Self Guided Walking Tour
Tijuana: Guided City Tour with Local Food and Beer Tasting
From Tijuana: Valle de Guadalupe Private Winery Tour
Top hotels in Otay Mesa
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Paradise Point Resort & Spa
"The staff was very friendly and very helpful."
Reviewed on 26 Aug 2026
Manchester Grand Hyatt San Diego
"Outstanding experience. The hotel exceeded expectations in every way. Room was gorgeous and spotless, staff so helpful, and the sushi at the Top of the Hyatt was to die for. I highly recommend!"
Reviewed on 25 Aug 2026
Wyndham San Diego Bayside
"It’s very close to everything only bad thing about staying there because he had to pay $50 a day to stay there"
Reviewed on 26 Aug 2026
The Dana on Mission Bay
Hard Rock Hotel San Diego
"Very friendly and quick service."
Reviewed on 26 Aug 2026
Where to stay in Otay Mesa
Downtown San Diego
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
Pacific Beach
The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Pacific Beach while you're exploring the area.
Mission Beach
If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.
Gaslamp Quarter
Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Nova SD – discover Gaslamp Quarter, a destination also famous for its shopping.
Mission Bay
If you're spending some time in Mission Bay, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.
