Otay Mesa Travel Guide
San Diego
Visit Otay Mesa
Stay near popular Otay Mesa attractions
Things to do
Tijuana Downtown Self Guided Walking Tour
Tijuana: Guided City Tour with Local Food and Beer Tasting
From Tijuana: Valle de Guadalupe Private Winery Tour
Top hotels in Otay Mesa
Paradise Point Resort & Spa
Manchester Grand Hyatt San Diego
"Always great service from the front desk, beautiful, clean property with everything near by. This is the only place we like to stay at when visiting San Diego."
Reviewed on 4 Aug 2026
Wyndham San Diego Bayside
"Front desk aurora very helpful friendly and professional. Thank you check in was great because of her"
Reviewed on 5 Aug 2026
The Dana on Mission Bay
Hard Rock Hotel San Diego
Bahia Resort Hotel
"A little dated, and could use some updates but what a magnificent location and wonderful staff."
Reviewed on 5 Aug 2026
Where to stay in Otay Mesa
Downtown San Diego
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Seaport Village are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
Pacific Beach
The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Riviera Shores Beach while you're exploring the area.
Mission Beach
If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.
Gaslamp Quarter
Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Spreckels Theater – discover Gaslamp Quarter, a destination also famous for its shopping.
Mission Bay
If you're spending some time in Mission Bay, Mission Bay and Ski Beach are top sights worth seeing.
