Otay Mesa Travel Guide
San Diego
Visit Otay Mesa
Stay near popular Otay Mesa attractions
Things to do
Tour of San Diego>Rosarito >Giant Christ>Puerto Nuevo Lobster
฿1,325
per adult
Tijuana Downtown Self Guided Walking Tour
฿323
per adult
100% of travellers recommend
Tijuana: Guided City Tour with Local Food and Beer Tasting
฿3,072
per adult
From Tijuana: Valle de Guadalupe Private Winery Tour
฿4,090
per adult
100% of travellers recommend
Top hotels in Otay Mesa
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
2296 Niels Bohr Ct San Diego CA
The price is ฿4,607 per night from 16 Aug to 17 Aug
฿4,607
฿5,240 total
16 Aug - 17 Aug
includes taxes & fees
Stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ...
Paradise Point Resort & Spa
1404 Vacation Rd San Diego CA
The price is ฿7,398 per night from 7 Sept to 8 Sept
฿7,398
฿10,257 total
7 Sept - 8 Sept
includes taxes & fees
Stay at this beach resort in San Diego. Enjoy free Wi-Fi, 5 outdoor pools and a full-service spa. Our guests praise the pool and the helpful staff in their reviews. ...
Manchester Grand Hyatt San Diego
1 Market Pl San Diego CA
The price is ฿6,165 per night from 30 Aug to 31 Aug
฿6,165
฿8,954 total
30 Aug - 31 Aug
includes taxes & fees
Stay at this business-friendly hotel in San Diego. Enjoy 6 restaurants, 3 bars/lounges and breakfast (surcharge). Our guests praise the pool and the helpful ...
9/10 Wonderful! (2,792 reviews)
"Fantastic location. Market is criminally expensive. $8 for cup of coffee!"
Reviewed on 14 Aug 2026
Wyndham San Diego Bayside
1355 N Harbor Drive San Diego CA
The price is ฿5,043 per night from 24 Aug to 25 Aug
฿5,043
฿7,000 total
24 Aug - 25 Aug
includes taxes & fees
Stay at this business-friendly hotel in San Diego. Enjoy free Wi-Fi, 3 restaurants and breakfast (surcharge). Our guests praise the pool and the restaurant in ...
8.4/10 Very good! (6,290 reviews)
"The hotel room felt quite dated. The room was quite dark, and the bathroom was outdated and in need of renovation The main thing I liked about the hotel was its convenient location."
Reviewed on 15 Aug 2026
The Dana on Mission Bay
1710 W Mission Bay Dr San Diego CA
The price is ฿6,264 per night from 7 Sept to 8 Sept
฿6,264
฿8,153 total
7 Sept - 8 Sept
includes taxes & fees
Stay at this hotel in San Diego. Enjoy 2 outdoor pools, a marina and 2 hot tubs. Our guests praise the pool and the restaurant in their reviews. Popular attractions ...
Hard Rock Hotel San Diego
207 5th Ave San Diego CA
Fully refundableReserve now, pay when you stay
The price is ฿5,869 per night from 8 Sept to 9 Sept
฿5,869
฿8,404 total
8 Sept - 9 Sept
includes taxes & fees
Stay at this hotel in San Diego. Enjoy free Wi-Fi, 2 restaurants and a nightclub. Our guests praise the helpful staff and the convenient parking in their reviews. ...
9/10 Wonderful! (4,210 reviews)
"Had a great stay. The issue we had was in the sports bar area. We were watching a fight on the TV and it got changed. I asked why and they said a lady was upset."
Reviewed on 14 Aug 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Otay Mesa
Find the best Otay Mesa areas for the activities you enjoy most.
Downtown San Diego
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
Pacific Beach
The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Pacific Beach while you're exploring the area.
Mission Beach
If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.
Gaslamp Quarter
Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Nova SD – discover Gaslamp Quarter, a destination also famous for its shopping.
Mission Bay
If you're spending some time in Mission Bay, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.
