Otay Mesa West Travel Guide
San Diego
Visit Otay Mesa West
Things to do
San Diego's City Harbor Sightseeing Cruise
USS Midway Museum with Direct-to-Gate
San Diego SEAL Tour by Land & Sea
San Diego Old Town Trolley Hop-On Hop-Off Tour
Top hotels in Otay Mesa West
Wyndham San Diego Bayside
"Clean room across from cruise ship terminal."
Reviewed on 3 Nov 2026
Hard Rock Hotel San Diego
"Staff and amenities were nice. Was somewhat disappointed in the bed mattress. That mattress has seen its time and should be replaced"
Reviewed on 3 Nov 2026
Paradise Point Resort & Spa
"Rooms are really nice, private & comfortable. Pools & hot tubs are clean & nice. Very beautiful property with lots of amenities"
Reviewed on 3 Nov 2026
Handlery Hotel
"I love that staff was friendly very helpful. The Fitness center. It was great. The pool was clean. I had no issue with my stay at all."
Reviewed on 3 Nov 2026
California Suites Hotel
Best Western Seven Seas
Where to stay in Otay Mesa West
Downtown San Diego
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
Pacific Beach
The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Pacific Beach while you're exploring the area.
Gaslamp Quarter
Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Nova SD – discover Gaslamp Quarter, a destination also famous for its shopping.
Mission Beach
If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.
Mission Bay
If you're spending some time in Mission Bay, Mission Bay and Ski Beach are top sights worth seeing.
