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Our top choices for Otay Mesa West hotels

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
2.5 star property
11 km from Otay Mesa West
8.2 out of 10, Very good, (1,752 reviews)
"Clean, friendly staff, great breakfast!!"
United States
Flor
The price is ฿4,754
฿5,408 total
includes taxes & fees
5 Jul - 6 Jul
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Best Western Americana Inn

Best Western Americana Inn
2.5 star property
2.1 km from Otay Mesa West
8.8 out of 10, Excellent, (1,318 reviews)
"The breakfast was great, the staff was helpful, and the room was clean and spacious!"
United States
Christopher
The price is ฿4,011
฿4,562 total
includes taxes & fees
5 Jul - 6 Jul
Best Western Americana Inn

Valli Hi Motel

Valli Hi Motel
2.5 star property
2.2 km from Otay Mesa West
8.4 out of 10, Very good, (1,010 reviews)
"Great place to stay."
United States
Allan
The price is ฿2,947
฿3,358 total
includes taxes & fees
21 Jun - 22 Jun
Valli Hi Motel

Sycuan Casino Resort

Sycuan Casino Resort
4.0 star property
31.2 km from Otay Mesa West
9.4 out of 10, Exceptional, (1,981 reviews)
"Always a great stay"
United States
Jeanette
The price is ฿3,790
฿4,563 total
includes taxes & fees
12 Jul - 13 Jul
Sycuan Casino Resort

Sheraton San Diego Resort

Sheraton San Diego Resort
4.0 star property
21.4 km from Otay Mesa West
8.4 out of 10, Very good, (3,531 reviews)
"Great location and shuttle service to and from the airport."
Canada
Malinda
The price is ฿5,220
฿7,659 total
includes taxes & fees
1 Jul - 2 Jul
Sheraton San Diego Resort

Hampton Inn & Suites San Diego Airport Liberty Station

Hampton Inn & Suites San Diego Airport Liberty Station
2.5 star property
22.4 km from Otay Mesa West
9.2 out of 10, Wonderful, (1,706 reviews)
"Good location, clean room and nice staff. A great place to stay."
United States
Patricia
The price is ฿5,612
฿6,451 total
includes taxes & fees
30 Jun - 1 Jul
Hampton Inn & Suites San Diego Airport Liberty Station

Motel 6 El Cajon, CA - San Diego

Motel 6 El Cajon, CA - San Diego
2.0 star property
26.3 km from Otay Mesa West
7.4 out of 10, Good, (1,702 reviews)
"A good place to stay if you need a place to crash in for the night"
United States
Ivy Ruth
The price is ฿2,396
฿2,640 total
includes taxes & fees
21 Jun - 22 Jun
Motel 6 El Cajon, CA - San Diego

Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld
3.0 star property
24.7 km from Otay Mesa West
7.4 out of 10, Good, (4,183 reviews)
"Clean room, staff was very helpful, parking was easy and accessible!"
United States
Hector
The price is ฿4,394
฿5,050 total
includes taxes & fees
29 Jun - 30 Jun
Wyndham Garden San Diego Near SeaWorld

Comfort Inn Chula Vista San Diego South

Comfort Inn Chula Vista San Diego South
2.5 star property
7.9 km from Otay Mesa West
8.2 out of 10, Very good, (1,555 reviews)
"The room was comfortable and conveniently located. Breakfast was great for the cost of our stay."
United States
Arsenia P
The price is ฿3,891
฿4,288 total
includes taxes & fees
12 Jul - 13 Jul
Comfort Inn Chula Vista San Diego South

Wyndham San Diego Bayside

Wyndham San Diego Bayside
4.0 star property
19.2 km from Otay Mesa West
8.4 out of 10, Very good, (6,212 reviews)
"Great place to stay if visiting san diego recommend"
United States
Carlos
The price is ฿5,282
฿7,266 total
includes taxes & fees
29 Jun - 30 Jun
Wyndham San Diego Bayside

Holiday Inn Express San Diego Airport - Old Town by IHG

Holiday Inn Express San Diego Airport - Old Town by IHG
2.5 star property
22.4 km from Otay Mesa West
9.2 out of 10, Wonderful, (1,078 reviews)
"Staff was so great nice rooms really great stay"
United States
Amelia
The price is ฿5,305
฿6,097 total
includes taxes & fees
30 Jun - 1 Jul
Holiday Inn Express San Diego Airport - Old Town by IHG

La Quinta Inn by Wyndham San Diego Chula Vista

La Quinta Inn by Wyndham San Diego Chula Vista
3.0 star property
7.8 km from Otay Mesa West
8.6 out of 10, Excellent, (1,629 reviews)
"Great place to stay at, would definitely stay there again."
United States
Jose
The price is ฿3,874
฿4,261 total
includes taxes & fees
19 Jul - 20 Jul
La Quinta Inn by Wyndham San Diego Chula Vista

Lafayette Hotel & Club

Lafayette Hotel & Club
4.0 star property
21.3 km from Otay Mesa West
9.4 out of 10, Exceptional, (1,732 reviews)
"Beautiful hotel"
United States
Cuauhtemoc
The price is ฿8,154
฿9,372 total
includes taxes & fees
30 Jun - 1 Jul
Lafayette Hotel & Club

Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel
3.5 star property
10.5 km from Otay Mesa West
9.2 out of 10, Wonderful, (3,878 reviews)
"Great stay"
United States
Cameron
The price is ฿5,865
฿6,463 total
includes taxes & fees
1 Jul - 2 Jul
Best Western Plus Marina Gateway Hotel

Best Western Yacht Harbor Hotel

Best Western Yacht Harbor Hotel
2.5 star property
22.9 km from Otay Mesa West
8.4 out of 10, Very good, (1,929 reviews)
The price is ฿3,962
฿4,547 total
includes taxes & fees
1 Jul - 2 Jul
Best Western Yacht Harbor Hotel

Courtyard by Marriott San Diego Airport/Liberty Station

Courtyard by Marriott San Diego Airport/Liberty Station
3.0 star property
22.8 km from Otay Mesa West
9.2 out of 10, Wonderful, (1,286 reviews)
"Was a lovely stay and it overlooks the water."
United States
Kara
The price is ฿6,391
฿7,346 total
includes taxes & fees
2 Jul - 3 Jul
Courtyard by Marriott San Diego Airport/Liberty Station

Crowne Plaza San Diego - Mission Valley by IHG

Crowne Plaza San Diego - Mission Valley by IHG
3.5 star property
23.7 km from Otay Mesa West
8.4 out of 10, Very good, (1,001 reviews)
"great stay"
United States
David
The price is ฿4,099
฿4,723 total
includes taxes & fees
29 Jun - 30 Jun
Crowne Plaza San Diego - Mission Valley by IHG

Best Western San Diego Pacific Beach/Mission Bay

Best Western San Diego Pacific Beach/Mission Bay
2.5 star property
Bay Park, 27.5 km from Otay Mesa West
8.2 out of 10, Very good, (432 reviews)
"Nice hotel."
United States
Aron
The price is ฿4,588
฿5,273 total
includes taxes & fees
30 Jun - 1 Jul
Best Western San Diego Pacific Beach/Mission Bay

Hampton Inn San Diego-Downtown

Hampton Inn San Diego-Downtown
2.5 star property
19.3 km from Otay Mesa West
8.2 out of 10, Very good, (2,573 reviews)
"Great location"
United States
Betty Ellen
The price is ฿4,845
฿5,617 total
includes taxes & fees
7 Jul - 8 Jul
Hampton Inn San Diego-Downtown

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego
4.0 star property
Gaslamp Quarter, 17.5 km from Otay Mesa West
9.0 out of 10, Wonderful, (3,849 reviews)
"Great stay overall!"
United States
Keanna
The price is ฿5,624
฿8,102 total
includes taxes & fees
25 Jun - 26 Jun
Hard Rock Hotel San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Otay Mesa West

Find the best Otay Mesa West areas for the activities you enjoy most.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

Mission Beach

If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.

Gaslamp Quarter

San Diego’s historic heart has shed its seedy past to emerge as one of the city’s premier dining, shopping and entertainment hubs.

Mission Bay

If you're spending some time in Mission Bay, Mission Bay and Ski Beach are top sights worth seeing.

Top Otay Mesa West Hotel Reviews

Frequently asked questions

What is Otay Mesa West like?
Otay Mesa West is a neighbourhood that travellers like for its cathedral.
If I need to cancel my hotel reservation in Otay Mesa West, will I receive a refund?
Yes! The majority of room reservations are refundable if you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a non-refundable reservation, you may still be able to cancel and receive a refund within 24 hours of your booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to review top deals in Otay Mesa West.
What is there to do around this San Diego neighbourhood?
A few places to visit in the area around Otay Mesa West include San Ysidro Border Crossing, Las Americas Premium Outlets and Sesame Place San Diego. While you're out sightseeing in San Diego, make sure that you visit other sights such as Tijuana Customs - Garita El Chaparral or North Island Credit Union Amphitheatre.
How can I get around Otay Mesa West and the greater San Diego area?
Ready to get out and explore the city? Iris Avenue Trolley Station is the closest metro station.