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Our top choices for Otay Mesa West hotels

Sheraton San Diego Resort

Sheraton San Diego Resort
4.0 star property
21.4 km from Otay Mesa West
8.4 out of 10, Very good, (3,541 reviews)
"Great location and shuttle service to and from the airport."
Canada
Malinda
The price is ฿5,248
฿7,700 total
includes taxes & fees
1 Jul - 2 Jul
Sheraton San Diego Resort

Valli Hi Motel

Valli Hi Motel
2.5 star property
2.2 km from Otay Mesa West
8.4 out of 10, Very good, (1,013 reviews)
"Great place to stay."
United States
Allan
The price is ฿2,967
฿3,381 total
includes taxes & fees
23 Jun - 24 Jun
Valli Hi Motel

Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld
3.0 star property
24.7 km from Otay Mesa West
7.4 out of 10, Good, (4,194 reviews)
"Clean room, staff was very helpful, parking was easy and accessible!"
United States
Hector
The price is ฿4,197
฿4,824 total
includes taxes & fees
29 Jun - 30 Jun
Wyndham Garden San Diego Near SeaWorld

Studio 6 Suites San Ysidro, CA -San Diego South Bay

Studio 6 Suites San Ysidro, CA -San Diego South Bay
2.5 star property
3.1 km from Otay Mesa West
8.0 out of 10, Very good, (1,690 reviews)
"It’s ok to stay one or two days"
United States
Valentina
The price is ฿2,604
฿2,967 total
includes taxes & fees
23 Jun - 24 Jun
Studio 6 Suites San Ysidro, CA -San Diego South Bay

Best Western Americana Inn

Best Western Americana Inn
2.5 star property
2.1 km from Otay Mesa West
8.8 out of 10, Excellent, (1,304 reviews)
"The breakfast was great, the staff was helpful, and the room was clean and spacious!"
United States
Christopher
The price is ฿4,032
฿4,587 total
includes taxes & fees
5 Jul - 6 Jul
Best Western Americana Inn

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
2.5 star property
11 km from Otay Mesa West
8.2 out of 10, Very good, (1,757 reviews)
"Clean, friendly staff, great breakfast!!"
United States
Flor
The price is ฿4,780
฿5,437 total
includes taxes & fees
5 Jul - 6 Jul
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Wyndham San Diego Bayside

Wyndham San Diego Bayside
4.0 star property
19.2 km from Otay Mesa West
8.4 out of 10, Very good, (6,230 reviews)
"Great place to stay if visiting san diego recommend"
United States
Carlos
The price is ฿5,311
฿7,304 total
includes taxes & fees
29 Jun - 30 Jun
Wyndham San Diego Bayside

Sycuan Casino Resort

Sycuan Casino Resort
4.0 star property
31.2 km from Otay Mesa West
9.4 out of 10, Exceptional, (1,985 reviews)
"Always a great stay"
United States
Jeanette
The price is ฿3,811
฿4,587 total
includes taxes & fees
12 Jul - 13 Jul
Sycuan Casino Resort

Hampton Inn & Suites San Diego Airport Liberty Station

Hampton Inn & Suites San Diego Airport Liberty Station
2.5 star property
22.4 km from Otay Mesa West
9.2 out of 10, Wonderful, (1,712 reviews)
"Good location, clean room and nice staff. A great place to stay."
United States
Patricia
The price is ฿5,650
฿6,494 total
includes taxes & fees
29 Jun - 30 Jun
Hampton Inn & Suites San Diego Airport Liberty Station

Lafayette Hotel & Club

Lafayette Hotel & Club
4.0 star property
21.3 km from Otay Mesa West
9.4 out of 10, Exceptional, (1,739 reviews)
"Beautiful hotel"
United States
Cuauhtemoc
The price is ฿8,208
฿9,435 total
includes taxes & fees
29 Jun - 30 Jun
Lafayette Hotel & Club

Crowne Plaza San Diego - Mission Valley by IHG

Crowne Plaza San Diego - Mission Valley by IHG
3.5 star property
23.7 km from Otay Mesa West
8.4 out of 10, Very good, (1,014 reviews)
"great stay"
United States
David
The price is ฿3,890
฿4,483 total
includes taxes & fees
29 Jun - 30 Jun
Crowne Plaza San Diego - Mission Valley by IHG

Old Town Inn

Old Town Inn
2.5 star property
23.7 km from Otay Mesa West
9.2 out of 10, Wonderful, (1,878 reviews)
"Clean room, good breakfast, comfortable pool area, friendly staff."
United States
Robert
The price is ฿5,506
฿6,318 total
includes taxes & fees
29 Jun - 30 Jun
Old Town Inn

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego
4.0 star property
Gaslamp Quarter, 17.5 km from Otay Mesa West
9.0 out of 10, Wonderful, (3,873 reviews)
"Great stay overall!"
United States
Keanna
The price is ฿5,662
฿8,156 total
includes taxes & fees
25 Jun - 26 Jun
Hard Rock Hotel San Diego

Heritage Inn San Diego

Heritage Inn San Diego
2.0 star property
25.2 km from Otay Mesa West
7.2 out of 10, Good, (1,545 reviews)
"Great stay"
United States
Alyssa
The price is ฿2,388
฿2,745 total
includes taxes & fees
28 Jun - 29 Jun
Heritage Inn San Diego

Hilton Garden Inn San Diego Old Town/SeaWorld Area

Hilton Garden Inn San Diego Old Town/SeaWorld Area
3.0 star property
Old Town San Diego, 24.1 km from Otay Mesa West
8.8 out of 10, Excellent, (1,464 reviews)
"Hotel is lovely mission style in keeping with the area. The location is very convenient to local attractions."
United States
Toni
The price is ฿4,721
฿5,426 total
includes taxes & fees
28 Jun - 29 Jun
Hilton Garden Inn San Diego Old Town/SeaWorld Area

Holiday Inn Express San Diego Airport - Old Town by IHG

Holiday Inn Express San Diego Airport - Old Town by IHG
2.5 star property
22.4 km from Otay Mesa West
9.2 out of 10, Wonderful, (1,083 reviews)
"Staff was so great nice rooms really great stay"
United States
Amelia
The price is ฿5,340
฿6,138 total
includes taxes & fees
30 Jun - 1 Jul
Holiday Inn Express San Diego Airport - Old Town by IHG

Sea Harbor Hotel

Sea Harbor Hotel
2.0 star property
23 km from Otay Mesa West
8.6 out of 10, Excellent, (1,008 reviews)
"Great location next to a peir side brewery and seafood restaurants"
United States
Ryan
The price is ฿3,918
฿4,417 total
includes taxes & fees
29 Jun - 30 Jun
Sea Harbor Hotel

DoubleTree by Hilton San Diego Bayside

DoubleTree by Hilton San Diego Bayside
3.0 star property
22.9 km from Otay Mesa West
8.4 out of 10, Very good, (1,034 reviews)
"Great stay!!! Recommend. So kind and our room was incredible!"
United States
Ana Maria
The price is ฿5,109
฿5,872 total
includes taxes & fees
19 Jul - 20 Jul
DoubleTree by Hilton San Diego Bayside

California Suites Hotel

California Suites Hotel
2.0 star property
30.6 km from Otay Mesa West
7.8 out of 10, Good, (2,656 reviews)
"Had a wonderful stay. Would stay here again"
United States
Ariana
The price is ฿3,234
฿3,711 total
includes taxes & fees
23 Jun - 24 Jun
California Suites Hotel

Courtyard by Marriott San Diego Airport/Liberty Station

Courtyard by Marriott San Diego Airport/Liberty Station
3.0 star property
22.8 km from Otay Mesa West
9.2 out of 10, Wonderful, (1,288 reviews)
"Was a lovely stay and it overlooks the water."
United States
Kara
The price is ฿6,425
฿7,385 total
includes taxes & fees
30 Jun - 1 Jul
Courtyard by Marriott San Diego Airport/Liberty Station
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Otay Mesa West

Find the best Otay Mesa West areas for the activities you enjoy most.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

Mission Beach

If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.

Gaslamp Quarter

San Diego’s historic heart has shed its seedy past to emerge as one of the city’s premier dining, shopping and entertainment hubs.

Mission Bay

If you're spending some time in Mission Bay, Mission Bay and Ski Beach are top sights worth seeing.

Top Otay Mesa West Hotel Reviews

Frequently asked questions

What is Otay Mesa West like?
Otay Mesa West is a neighbourhood that travellers like for its cathedral.
If I need to cancel my hotel reservation in Otay Mesa West, will I receive a refund?
Yes! The majority of room reservations are refundable if you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a non-refundable reservation, you may still be able to cancel and receive a refund within 24 hours of your booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to review top deals in Otay Mesa West.
What is there to do around this San Diego neighbourhood?
A few places to visit in the area around Otay Mesa West include San Ysidro Border Crossing, Las Americas Premium Outlets and Sesame Place San Diego. While you're out sightseeing in San Diego, make sure that you visit other sights such as Tijuana Customs - Garita El Chaparral or North Island Credit Union Amphitheatre.
How can I get around Otay Mesa West and the greater San Diego area?
Ready to get out and explore the city? Iris Avenue Trolley Station is the closest metro station.