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Our top choices for Otay Mesa West hotels

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
2.5 star property
11 km from Otay Mesa West
8.2 out of 10, Very good, (1,764 reviews)
"Clean, friendly staff, great breakfast!!"
United States
Flor
The price is ฿4,973
฿5,657 total
includes taxes & fees
30 Jun - 1 Jul
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Best Western Americana Inn

Best Western Americana Inn
2.5 star property
2.1 km from Otay Mesa West
8.8 out of 10, Excellent, (1,316 reviews)
"The breakfast was great, the staff was helpful, and the room was clean and spacious!"
United States
Christopher
The price is ฿4,083
฿4,644 total
includes taxes & fees
5 Jul - 6 Jul
Best Western Americana Inn

Hampton Inn & Suites San Diego Airport Liberty Station

Hampton Inn & Suites San Diego Airport Liberty Station
2.5 star property
22.4 km from Otay Mesa West
9.2 out of 10, Wonderful, (1,708 reviews)
"Good location, clean room and nice staff. A great place to stay."
United States
Patricia
The price is ฿5,720
฿6,575 total
includes taxes & fees
19 Jul - 20 Jul
Hampton Inn & Suites San Diego Airport Liberty Station

Ayres Hotel San Diego South - Chula Vista

Ayres Hotel San Diego South - Chula Vista
3.0 star property
9.2 km from Otay Mesa West
9.8 out of 10, Exceptional, (1,097 reviews)
"Nice place good food for breakfast 👍"
United States
Paul
The price is ฿7,059
฿7,779 total
includes taxes & fees
19 Jul - 20 Jul
Ayres Hotel San Diego South - Chula Vista

Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel
3.5 star property
10.5 km from Otay Mesa West
9.2 out of 10, Wonderful, (3,898 reviews)
"Great stay"
United States
Cameron
The price is ฿5,307
฿5,848 total
includes taxes & fees
30 Jun - 1 Jul
Best Western Plus Marina Gateway Hotel

Sycuan Casino Resort

Sycuan Casino Resort
4.0 star property
31.2 km from Otay Mesa West
9.4 out of 10, Exceptional, (1,993 reviews)
"Always a great stay"
United States
Jeanette
The price is ฿3,858
฿4,645 total
includes taxes & fees
12 Jul - 13 Jul
Sycuan Casino Resort

Comfort Inn Chula Vista San Diego South

Comfort Inn Chula Vista San Diego South
2.5 star property
7.9 km from Otay Mesa West
8.2 out of 10, Very good, (1,574 reviews)
"The room was comfortable and conveniently located. Breakfast was great for the cost of our stay."
United States
Arsenia P
The price is ฿4,476
฿4,932 total
includes taxes & fees
5 Jul - 6 Jul
Comfort Inn Chula Vista San Diego South

La Quinta Inn by Wyndham San Diego Chula Vista

La Quinta Inn by Wyndham San Diego Chula Vista
3.0 star property
7.8 km from Otay Mesa West
8.6 out of 10, Excellent, (1,642 reviews)
"Great place to stay at, would definitely stay there again."
United States
Jose
The price is ฿4,085
฿4,494 total
includes taxes & fees
19 Jul - 20 Jul
La Quinta Inn by Wyndham San Diego Chula Vista

WoodSpring Suites Santee - San Diego Northeast

WoodSpring Suites Santee - San Diego Northeast
2.5 star property
29.1 km from Otay Mesa West
8.4 out of 10, Very good, (138 reviews)
"This property has all amenities travelers would need; including clean room, accessible laundry facility, complimentary parking and wonderful friendly staff."
United States
Lorenzo Gregorio
The price is ฿3,471
฿3,818 total
includes taxes & fees
1 Jul - 2 Jul
WoodSpring Suites Santee - San Diego Northeast

Hampton Inn San Diego-Kearny Mesa

Hampton Inn San Diego-Kearny Mesa
2.5 star property
29.7 km from Otay Mesa West
9.2 out of 10, Wonderful, (1,002 reviews)
"Great place for kids and adults."
United States
Susana
The price is ฿6,275
฿7,200 total
includes taxes & fees
30 Jun - 1 Jul
Hampton Inn San Diego-Kearny Mesa

Holiday Inn Express San Diego South - Chula Vista by IHG

Holiday Inn Express San Diego South - Chula Vista by IHG
2.5 star property
8 km from Otay Mesa West
9.4 out of 10, Exceptional, (1,265 reviews)
"We had a very wonderful time at our stay here"
United States
Liezl
The price is ฿5,929
฿6,523 total
includes taxes & fees
5 Jul - 6 Jul
Holiday Inn Express San Diego South - Chula Vista by IHG

Best Western Chula Vista/Otay Valley Hotel

Best Western Chula Vista/Otay Valley Hotel
2.5 star property
2.4 km from Otay Mesa West
8.0 out of 10, Very good, (1,838 reviews)
"The stay was great, and breakfast was delicious"
United States
Katie
The price is ฿3,943
฿4,346 total
includes taxes & fees
5 Jul - 6 Jul
Best Western Chula Vista/Otay Valley Hotel

Valli Hi Motel

Valli Hi Motel
2.5 star property
2.2 km from Otay Mesa West
8.4 out of 10, Very good, (1,027 reviews)
"Great place to stay."
United States
Allan
The price is ฿3,004
฿3,423 total
includes taxes & fees
30 Jun - 1 Jul
Valli Hi Motel

Homewood Suites by Hilton San Diego Airport/Liberty Station

Homewood Suites by Hilton San Diego Airport/Liberty Station
3.0 star property
22.7 km from Otay Mesa West
9.4 out of 10, Exceptional, (1,561 reviews)
"Great stay, everything was outstanding"
United States
Bill
The price is ฿7,645
฿8,788 total
includes taxes & fees
20 Jul - 21 Jul
Homewood Suites by Hilton San Diego Airport/Liberty Station

Sheraton San Diego Resort

Sheraton San Diego Resort
4.0 star property
21.4 km from Otay Mesa West
8.4 out of 10, Very good, (3,545 reviews)
"Great location and shuttle service to and from the airport."
Canada
Malinda
The price is ฿5,641
฿8,172 total
includes taxes & fees
2 Jul - 3 Jul
Sheraton San Diego Resort

SpringHill Suites by Marriott Chula Vista Eastlake

SpringHill Suites by Marriott Chula Vista Eastlake
3.5 star property
12.4 km from Otay Mesa West
9.6 out of 10, Exceptional, (680 reviews)
"It was great, one of the best stays we have had while traveling this year!"
United States
Ken
The price is ฿8,008
฿8,825 total
includes taxes & fees
20 Jul - 21 Jul
SpringHill Suites by Marriott Chula Vista Eastlake

Days Inn by Wyndham San Diego-East/El Cajon

Days Inn by Wyndham San Diego-East/El Cajon
2.0 star property
27 km from Otay Mesa West
7.8 out of 10, Good, (1,007 reviews)
"Rooms were cheap clean property was clean convenient close to where I was working"
United States
James
The price is ฿3,972
฿4,377 total
includes taxes & fees
30 Jun - 1 Jul
Days Inn by Wyndham San Diego-East/El Cajon

Pleasant Inn

Pleasant Inn
2.5 star property
30.7 km from Otay Mesa West
8.6 out of 10, Excellent, (1,466 reviews)
"Staff were very accommodating & friendly the room was clean i would stay there again!"
United States
Scott
The price is ฿3,617
฿4,151 total
includes taxes & fees
20 Jul - 21 Jul
Pleasant Inn

Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld
3.0 star property
24.7 km from Otay Mesa West
7.4 out of 10, Good, (4,177 reviews)
"Clean room, staff was very helpful, parking was easy and accessible!"
United States
Hector
The price is ฿4,306
฿4,949 total
includes taxes & fees
1 Jul - 2 Jul
Wyndham Garden San Diego Near SeaWorld

GreenTree Inn San Diego Mission Bay

GreenTree Inn San Diego Mission Bay
2.5 star property
Pacific Beach, 29.3 km from Otay Mesa West
8.0 out of 10, Very good, (2,203 reviews)
"THE BED WAS SO SOFT ROOM WAS SO CLEAN BREAKFAST WAS GREAT AND THE PRICE WAS KILLER FOR THE LOCATION really a great place to stay"
United States
Tyson
The price is ฿3,955
฿4,546 total
includes taxes & fees
6 Jul - 7 Jul
GreenTree Inn San Diego Mission Bay
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Otay Mesa West

Find the best Otay Mesa West areas for the activities you enjoy most.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

Mission Beach

If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.

Gaslamp Quarter

San Diego’s historic heart has shed its seedy past to emerge as one of the city’s premier dining, shopping and entertainment hubs.

Mission Bay

If you're spending some time in Mission Bay, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.

Top Otay Mesa West Hotel Reviews

Frequently asked questions

What is Otay Mesa West like?
Otay Mesa West is a neighbourhood that travellers like for its cathedral.
If I need to cancel my hotel reservation in Otay Mesa West, will I receive a refund?
Yes! The majority of room reservations are refundable if you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a non-refundable reservation, you may still be able to cancel and receive a refund within 24 hours of your booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to review top deals in Otay Mesa West.
What is there to do around this San Diego neighbourhood?
A few places to visit in the area around Otay Mesa West include San Ysidro Border Crossing, Las Americas Premium Outlets and Sesame Place San Diego. While you're out sightseeing in San Diego, make sure that you visit other sights such as Tijuana Customs - Garita El Chaparral or North Island Credit Union Amphitheatre.
How can I get around Otay Mesa West and the greater San Diego area?
Ready to get out and explore the city? Iris Avenue Trolley Station is the closest metro station.