Mission Bay Travel Guide

San Diego

An aerial view of a coastal city with a marina, a large body of water, and a peninsula with buildings.

Stay near popular Mission Bay attractions

Things to do


Top hotels in Mission Bay

Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
The price is ฿6,929 per night from 4 Oct to 5 Oct
฿6,929
฿9,728 total
4 Oct - 5 Oct
includes taxes & fees
Stay at this beach resort in San Diego. Enjoy free Wi-Fi, 5 outdoor pools and a full-service spa. Our guests praise the pool and the helpful staff in their reviews. ...
Paradise Point Resort & Spa
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr San Diego CA
Fully refundableReserve now, pay when you stay
The price is ฿5,636 per night from 29 Sept to 30 Sept
฿5,636
฿7,436 total
29 Sept - 30 Sept
includes taxes & fees
Stay at this hotel in San Diego. Enjoy 2 outdoor pools, a marina and 2 hot tubs. Our guests praise the pool and the restaurant in their reviews. Popular attractions ...
9/10 Wonderful! (4,441 reviews)
"Stayed here for a family getaway and had an amazing time with the kids! The property grounds are absolutely beautiful, but the highlight was the staff. They were incredibly thoughtful, caring, and went out of their way to make sure our family was comfortable. It is the perfect place for a stress-free ..."

Reviewed on 19 Sept 2026

The Dana on Mission Bay
San Diego Mission Bay Resort

San Diego Mission Bay Resort

4 out of 5
1775 E Mission Bay Dr San Diego CA
The price is ฿8,297 per night from 19 Oct to 20 Oct
฿8,297
฿11,299 total
19 Oct - 20 Oct
includes taxes & fees
Stay at this spa resort in San Diego. Enjoy free Wi-Fi, a full-service spa and 2 restaurants. Our guests praise the pool and the helpful staff in their reviews. ...
San Diego Mission Bay Resort
Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina

4 out of 5
1441 Quivira Rd San Diego CA
The price is ฿6,631 per night from 30 Sept to 1 Oct
฿6,631
฿9,385 total
30 Sept - 1 Oct
includes taxes & fees
Stay at this spa hotel in San Diego. Enjoy free Wi-Fi, 3 outdoor pools and a full-service spa. Our guests praise the pool and the helpful staff in their reviews. ...
Hyatt Regency Mission Bay Spa and Marina
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N San Diego CA
The price is ฿3,705 per night from 21 Sept to 22 Sept
฿3,705
฿4,259 total
21 Sept - 22 Sept
includes taxes & fees
Stay at this business-friendly hotel in San Diego. Enjoy free Wi-Fi, 2 restaurants and 2 bars/lounges. Our guests praise the pool and the helpful staff in their ...
Handlery Hotel
Best Western Seven Seas

Best Western Seven Seas

3 out of 5
411 Hotel Circle South San Diego CA
The price is ฿2,819 per night from 21 Sept to 22 Sept
฿2,819
฿3,240 total
21 Sept - 22 Sept
includes taxes & fees
Stay at this business-friendly hotel in San Diego. Enjoy free Wi-Fi, free parking and 2 hot tubs. Our guests praise the pool and the restaurant in their reviews. ...
8/10 Very good! (3,920 reviews)
"Always a nice place to stay short or long term"

Reviewed on 19 Sept 2026

Best Western Seven Seas
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Mission Bay

Find the best Mission Bay areas for the activities you enjoy most.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Pacific Beach

The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Pacific Beach while you're exploring the area.

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Gaslamp Quarter

Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Lyceum Theatre – discover Gaslamp Quarter, a destination also famous for its shopping.

Ocean Beach

Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Ocean Beach and Dog Beach.



Mission Bay Travel Guide