Mission Bay Travel Guide

San Diego

An aerial view of a coastal city with a marina, a large body of water, and a peninsula with buildings.

Stay near popular Mission Bay attractions

Things to do


Top hotels in Mission Bay

Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
The price is ฿6,905 per night from 8 Nov to 9 Nov
฿6,905
฿9,712 total
8 Nov - 9 Nov
includes taxes & fees
Stay at this beach resort in San Diego. Enjoy free Wi-Fi, 5 outdoor pools and a full-service spa. Our guests praise the pool and the helpful staff in their reviews. ...
Paradise Point Resort & Spa
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr San Diego CA
The price is ฿6,002 per night from 3 Nov to 4 Nov
฿6,002
฿7,863 total
3 Nov - 4 Nov
includes taxes & fees
Stay at this hotel in San Diego. Enjoy 2 outdoor pools, a marina and 2 hot tubs. Our guests praise the pool and the restaurant in their reviews. Popular attractions ...
The Dana on Mission Bay
Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina

4 out of 5
1441 Quivira Rd San Diego CA
The price is ฿6,807 per night from 5 Nov to 6 Nov
฿6,807
฿9,598 total
5 Nov - 6 Nov
includes taxes & fees
Stay at this spa hotel in San Diego. Enjoy free Wi-Fi, 3 outdoor pools and a full-service spa. Our guests praise the pool and the helpful staff in their reviews. ...
8.4/10 Very good! (1,642 reviews)
"Beautiful and the breakfast was delicious!"

Reviewed on 11 Oct 2026

Hyatt Regency Mission Bay Spa and Marina
San Diego Mission Bay Resort

San Diego Mission Bay Resort

4 out of 5
1775 E Mission Bay Dr San Diego CA
The price is ฿7,343 per night from 28 Oct to 29 Oct
฿7,343
฿10,214 total
28 Oct - 29 Oct
includes taxes & fees
Stay at this spa resort in San Diego. Enjoy free Wi-Fi, a full-service spa and 2 restaurants. Our guests praise the pool and the helpful staff in their reviews. ...
San Diego Mission Bay Resort
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
The price is ฿5,102 per night from 25 Oct to 26 Oct
฿5,102
฿7,082 total
25 Oct - 26 Oct
includes taxes & fees
Stay at this business-friendly hotel in San Diego. Enjoy free Wi-Fi, 3 restaurants and breakfast (surcharge). Our guests praise the pool and the restaurant in ...
Wyndham San Diego Bayside
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N San Diego CA
Fully refundable
The price is ฿3,107 per night from 15 Oct to 16 Oct
฿3,107
฿3,957 total
15 Oct - 16 Oct
includes taxes & fees
Stay at this business-friendly hotel in San Diego. Enjoy free Wi-Fi, 2 restaurants and 2 bars/lounges. Our guests praise the pool and the helpful staff in their ...
8.4/10 Very good! (2,989 reviews)
"Staff was helpful and welcoming. The room was clean and quiet. Would go back again!"

Reviewed on 10 Oct 2026

Handlery Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Mission Bay

Find the best Mission Bay areas for the activities you enjoy most.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Pacific Beach

The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Pacific Beach while you're exploring the area.

Gaslamp Quarter

Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Nova SD – discover Gaslamp Quarter, a destination also famous for its shopping.

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Ocean Beach

Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Ocean Beach and Dog Beach.



Mission Bay Travel Guide