Mission Bay Travel Guide

San Diego

An aerial view of a coastal city with a marina, a large body of water, and a peninsula with buildings.

Stay near popular Mission Bay attractions

Things to do


Top hotels in Mission Bay

Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
The price is ฿6,966 per night from 30 Oct to 31 Oct
฿6,966
฿9,784 total
30 Oct - 31 Oct
includes taxes & fees
Stay at this beach resort in San Diego. Enjoy free Wi-Fi, 5 outdoor pools and a full-service spa. Our guests praise the pool and the helpful staff in their reviews. ...
Paradise Point Resort & Spa
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr San Diego CA
The price is ฿5,677 per night from 1 Nov to 2 Nov
฿5,677
฿7,489 total
1 Nov - 2 Nov
includes taxes & fees
Stay at this hotel in San Diego. Enjoy 2 outdoor pools, a marina and 2 hot tubs. Our guests praise the pool and the restaurant in their reviews. Popular attractions ...
9/10 Wonderful! (4,446 reviews)
"Housekeeping entered my room with one knock. Room had an odor and it was very hot in the room. They did keep the property on the outside nice. Firefly was a great restaurant."

Reviewed on 4 Oct 2026

The Dana on Mission Bay
Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina

4 out of 5
1441 Quivira Rd San Diego CA
The price is ฿7,249 per night from 1 Nov to 2 Nov
฿7,249
฿10,108 total
1 Nov - 2 Nov
includes taxes & fees
Stay at this spa hotel in San Diego. Enjoy free Wi-Fi, 3 outdoor pools and a full-service spa. Our guests praise the pool and the helpful staff in their reviews. ...
8.4/10 Very good! (1,638 reviews)
"Overall, our stay was very good! The staff was friendly, and there were plenty of things to do, especially for families with kids. They have free marshmallow bonfires, complimentary shuttles to the sea world, ping-pong, movie nights, and other fun kids’ activities. The breakfast was okay, but overall, ..."

Reviewed on 4 Oct 2026

Hyatt Regency Mission Bay Spa and Marina
San Diego Mission Bay Resort

San Diego Mission Bay Resort

4 out of 5
1775 E Mission Bay Dr San Diego CA
Fully refundableReserve now, pay when you stay
The price is ฿8,021 per night from 28 Oct to 29 Oct
฿8,021
฿10,994 total
28 Oct - 29 Oct
includes taxes & fees
Stay at this spa resort in San Diego. Enjoy free Wi-Fi, a full-service spa and 2 restaurants. Our guests praise the pool and the helpful staff in their reviews. ...
8.6/10 Excellent! (1,634 reviews)
"The pool was out of service for three days, the rooms are old and musty smelling. Not what I expected from this resort. The experience was very poor for the money we paid for two rooms."

Reviewed on 3 Oct 2026

San Diego Mission Bay Resort
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
The price is ฿5,106 per night from 25 Oct to 26 Oct
฿5,106
฿7,088 total
25 Oct - 26 Oct
includes taxes & fees
Stay at this business-friendly hotel in San Diego. Enjoy free Wi-Fi, 3 restaurants and breakfast (surcharge). Our guests praise the pool and the restaurant in ...
Wyndham San Diego Bayside
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N San Diego CA
The price is ฿3,463 per night from 5 Oct to 6 Oct
฿3,463
฿3,981 total
5 Oct - 6 Oct
includes taxes & fees
Stay at this business-friendly hotel in San Diego. Enjoy free Wi-Fi, 2 restaurants and 2 bars/lounges. Our guests praise the pool and the helpful staff in their ...
8.4/10 Very good! (2,971 reviews)
"Always a great stay!!!!"

Reviewed on 4 Oct 2026

Handlery Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Mission Bay

Find the best Mission Bay areas for the activities you enjoy most.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Pacific Beach

The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Pacific Beach while you're exploring the area.

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Gaslamp Quarter

Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Nova SD – discover Gaslamp Quarter, a destination also famous for its shopping.

Ocean Beach

Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Ocean Beach and Dog Beach.



Mission Bay Travel Guide