Mission Bay Travel Guide

San Diego

An aerial view of a coastal city with a marina, a large body of water, and a peninsula with buildings.

Stay near popular Mission Bay attractions

Things to do


Top hotels in Mission Bay

Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
The price is ฿6,969 per night from 1 Nov to 2 Nov
฿6,969
฿9,785 total
1 Nov - 2 Nov
includes taxes & fees
Stay at this beach resort in San Diego. Enjoy free Wi-Fi, 5 outdoor pools and a full-service spa. Our guests praise the pool and the helpful staff in their reviews. ...
8.8/10 Excellent! (2,933 reviews)
"Room was clean and spacious with lots of drawers for storage. Small refrigerator, no microwave. Lots of extra towels, and an extra pillow. Ironing board and iron, nice spa quality toiletries. Parking close to room but shocked at $50/night charge for parking. Gardens and ponds everywhere, beautiful. ..."

Reviewed on 15 Oct 2026

Paradise Point Resort & Spa
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr San Diego CA
Fully refundableReserve now, pay when you stay
The price is ฿5,999 per night from 4 Nov to 5 Nov
฿5,999
฿7,859 total
4 Nov - 5 Nov
includes taxes & fees
Stay at this hotel in San Diego. Enjoy 2 outdoor pools, a marina and 2 hot tubs. Our guests praise the pool and the restaurant in their reviews. Popular attractions ...
9/10 Wonderful! (4,470 reviews)
"The view of the marina is amazing and the entire premises feels like a relaxing resort. Because it is."

Reviewed on 15 Oct 2026

The Dana on Mission Bay
Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina

4 out of 5
1441 Quivira Rd San Diego CA
The price is ฿7,105 per night from 5 Nov to 6 Nov
฿7,105
฿9,940 total
5 Nov - 6 Nov
includes taxes & fees
Stay at this spa hotel in San Diego. Enjoy free Wi-Fi, 3 outdoor pools and a full-service spa. Our guests praise the pool and the helpful staff in their reviews. ...
Hyatt Regency Mission Bay Spa and Marina
San Diego Mission Bay Resort

San Diego Mission Bay Resort

4 out of 5
1775 E Mission Bay Dr San Diego CA
The price is ฿7,005 per night from 28 Oct to 29 Oct
฿7,005
฿9,824 total
28 Oct - 29 Oct
includes taxes & fees
Stay at this spa resort in San Diego. Enjoy free Wi-Fi, a full-service spa and 2 restaurants. Our guests praise the pool and the helpful staff in their reviews. ...
San Diego Mission Bay Resort
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
The price is ฿5,099 per night from 25 Oct to 26 Oct
฿5,099
฿7,079 total
25 Oct - 26 Oct
includes taxes & fees
Stay at this business-friendly hotel in San Diego. Enjoy free Wi-Fi, 3 restaurants and breakfast (surcharge). Our guests praise the pool and the restaurant in ...
8.4/10 Very good! (6,343 reviews)
"Generally a great stay. Definitely a wonderful location. We had a harbor view room and it was great just to sit on the balcony and enjoy the scenery. All the staff were A+ Our bathroom was a little worn looking and the toilet plumbing needed to be adjusted."

Reviewed on 16 Oct 2026

Wyndham San Diego Bayside
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N San Diego CA
The price is ฿3,196 per night from 9 Nov to 10 Nov
฿3,196
฿3,673 total
9 Nov - 10 Nov
includes taxes & fees
Stay at this business-friendly hotel in San Diego. Enjoy free Wi-Fi, 2 restaurants and 2 bars/lounges. Our guests praise the pool and the helpful staff in their ...
8.4/10 Very good! (3,011 reviews)
"The staff from the restaurant were amazing!!! They went above and beyond!!! I forgot there names but it was a female and two males working when we ate at the restaurant, we ate there three times. They were so nice, polite and so attentive!!! Pamela lady from the front desk when we checked out she ..."

Reviewed on 16 Oct 2026

Handlery Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Mission Bay

Find the best Mission Bay areas for the activities you enjoy most.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Pacific Beach

The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Pacific Beach while you're exploring the area.

Gaslamp Quarter

Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Nova SD – discover Gaslamp Quarter, a destination also famous for its shopping.

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Point Loma

Seaside views a bustling port and top sights from Marine Corps Recruit Depot to Shelter Island – discover Point Loma, a destination also famous for its island views.



Mission Bay Travel Guide