Medical Center District Travel Guide
San Antonio
Visit Medical Center District
Stay near popular Medical Center District attractions
Things to do
San Antonio Zoo Any Day Ticket
฿988
per adult
96% of travellers recommend
San Antonio: Witte Museum Admission Ticket
฿568
per adult
86% of travellers recommend
San Antonio: Fredericksburg Wineries Day Trip with Tastings
฿5,976
per adult
100% of travellers recommend
Dining at Hard Rock Cafe San Antonio
฿1,335
per traveller
76% of travellers recommend
The Undead: Zombie Apocalypse Escape Room at Extreme Escape
฿1,068
per adult
Top hotels in Medical Center District
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
4431 Horizon Hill Blvd San Antonio TX
The price is ฿2,998 per night from 27 Oct to 28 Oct
฿2,998
฿3,570 total
27 Oct - 28 Oct
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very good! (3,747 reviews)
"The bathroom was gross and I now have athletes foot. Showers definitely aren’t worthy of the Wyndham name"
Reviewed on 26 Oct 2026
San Antonio Marriott Northwest Medical Center
3233 NW Loop 410 San Antonio TX
The price is ฿3,147 per night from 25 Nov to 26 Nov
฿3,147
฿3,767 total
25 Nov - 26 Nov
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy room service, a 24-hour fitness centre and Wi-Fi (surcharge). Our guests praise the helpful staff ...
8.6/10 Excellent! (1,183 reviews)
"Good choice"
Reviewed on 26 Oct 2026
Drury Inn & Suites San Antonio Northwest Medical Center
9806 Interstate Hwy 10 W San Antonio TX
The price is ฿3,038 per night from 5 Nov to 6 Nov
฿3,038
฿3,618 total
5 Nov - 6 Nov
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
Courtyard by Marriott Medical Center San Antonio
8585 Marriott Dr San Antonio TX
The price is ฿3,008 per night from 13 Nov to 14 Nov
฿3,008
฿3,583 total
13 Nov - 14 Nov
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
Hotel Valencia Riverwalk
150 E Houston St San Antonio TX
The price is ฿4,224 per night from 27 Oct to 28 Oct
฿4,224
฿5,995 total
27 Oct - 28 Oct
includes taxes & fees
Stay at this luxury hotel in San Antonio. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff and the clean rooms in ...
9.4/10 Exceptional! (3,244 reviews)
"Great stay. Close to everything. My only regret is not staying longer"
Reviewed on 26 Oct 2026
Drury Plaza Hotel San Antonio Riverwalk
105 S Saint Marys Street San Antonio TX
The price is ฿4,321 per night from 8 Nov to 9 Nov
฿4,321
฿5,146 total
8 Nov - 9 Nov
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and 2 hot tubs. Our guests praise the breakfast and the pool in their reviews. ...
9.4/10 Exceptional! (5,437 reviews)
"Very friendly staff, lots of food options included with stay although we didn’t eat much there. Tellers bar/grill had amazing pizza. Overall we had a nice, clean, and comfortable stay."
Reviewed on 26 Oct 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Check Medical Center District hotel availability
Where to stay in Medical Center District
Find the best Medical Center District areas for the activities you enjoy most.
Downtown San Antonio
A scenic riverfront great entertainment and top sights from Alamo to Alamodome – discover Downtown San Antonio, a destination also famous for its historic sites.
Uptown Central
If you're spending some time in Uptown Central, Marion Koogler McNay Art Museum and Alamo Quarry Market are top sights worth seeing.
Far West Side
While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.
Northwest Side
If you're spending some time in Northwest Side, Huebner Oaks and Crystal Ice Palace are top sights worth seeing.
Stone Oak
Stone Oak is known for its abundant dining options, and you can plan a trip to Shops at Hardy Oak and Alta Vista at Stone Oak while you're in town.
