Search Hotels in Medical District, Memphis

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29 Dec - 30 Dec
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30 Dec - 31 Dec
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2 Jan - 4 Jan
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Our top choices for Medical District hotels

Exterior
Motel 6 Memphis, TN - Downtown

Motel 6 Memphis, TN - Downtown

Motel 6 Memphis, TN - Downtown
2.0 star property
Medical District
5.6 out of 10, (1001)
"Room was clean and smelled fresh/sanitized. Hotel is well gated and secured"
United States
Antonio
The price is ฿1,516
฿1,862 total
includes taxes & fees
30 Dec - 31 Dec
Motel 6 Memphis, TN - Downtown
Room, 2 Queen Beds | Minibar, free WiFi, bed sheets
Capital O Kings Inn

Capital O Kings Inn

Capital O Kings Inn
2.5 star property
Medical District
5.4 out of 10, (29)
"No room service for an entire week, Will never stay there again. "
United States
Ian
The price is ฿1,507
฿2,069 total
includes taxes & fees
30 Dec - 31 Dec
Capital O Kings Inn
Outdoor pool
Comfort Inn Horn Lake - Southhaven

Comfort Inn Horn Lake - Southhaven

Comfort Inn Horn Lake - Southhaven
2.5 star property
19.4 km from Medical District
8.2 out of 10, Very good, (605)
"Ideal place for a short stay. I was very pleased!"
United States
Kenya
The price is ฿2,722
฿3,029 total
includes taxes & fees
4 Jan - 5 Jan 2026
Comfort Inn Horn Lake - Southhaven
Exterior
Sleep Inn Horn Lake - Southaven

Sleep Inn Horn Lake - Southaven

Sleep Inn Horn Lake - Southaven
2.5 star property
19.8 km from Medical District
7.6 out of 10, Good, (689)
"The stay was very good. Room was clean. Nice location with a lot of amenties in the area. Clean and quiet location. "
Canada
Michael
The price is ฿2,197
฿2,457 total
includes taxes & fees
11 Jan - 12 Jan 2026
Sleep Inn Horn Lake - Southaven
Exterior
Best Western Plus Galleria Inn & Suites

Best Western Plus Galleria Inn & Suites

Best Western Plus Galleria Inn & Suites
2.5 star property
Wolfchase, 24.6 km from Medical District
7.8 out of 10, Good, (1017)
"Very nice place to stay."
United States
Jack
The price is ฿2,403
฿2,916 total
includes taxes & fees
1 Jan - 2 Jan 2026
Best Western Plus Galleria Inn & Suites
Lobby
Wingate by Wyndham Horn Lake Southaven

Wingate by Wyndham Horn Lake Southaven

Wingate by Wyndham Horn Lake Southaven
2.0 star property
20 km from Medical District
7.4 out of 10, Good, (583)
"yes , yes , yes would gladly stay again "
United States
Starla
The price is ฿2,348
฿2,621 total
includes taxes & fees
11 Jan - 12 Jan 2026
Wingate by Wyndham Horn Lake Southaven
Lobby
Days Inn & Suites by Wyndham Horn Lake/Memphis Graceland

Days Inn & Suites by Wyndham Horn Lake/Memphis Graceland

Days Inn & Suites by Wyndham Horn Lake/Memphis Graceland
2.0 star property
19.7 km from Medical District
8.4 out of 10, Very good, (598)
"Quiet and nice are. The hotel is close to many food and shopping places. The breakfast wasn’t what we expected. No eggs, meat, nor grits. "
United States
Ashley
The price is ฿2,653
฿2,955 total
includes taxes & fees
30 Dec - 31 Dec
Days Inn & Suites by Wyndham Horn Lake/Memphis Graceland
Lobby
Homestay Horn Lake / Southaven MS

Homestay Horn Lake / Southaven MS

Homestay Horn Lake / Southaven MS
2.5 star property
20 km from Medical District
7.2 out of 10, Good, (1004)
"Everything was decent...I was only there as a resting i"
United States
Derrick
The price is ฿2,110
฿2,362 total
includes taxes & fees
28 Jan - 29 Jan 2026
Homestay Horn Lake / Southaven MS
Lunch and dinner served, American cuisine
Hyatt Place Memphis/Wolfchase Galleria

Hyatt Place Memphis/Wolfchase Galleria

Hyatt Place Memphis/Wolfchase Galleria
3.0 star property
Wolfchase, 22.4 km from Medical District
9.0 out of 10, Wonderful, (1390)
"Great breakfast selection, cleanliness "
United States
JACQUE
The price is ฿2,731
฿3,305 total
includes taxes & fees
11 Jan - 12 Jan 2026
Hyatt Place Memphis/Wolfchase Galleria
Free buffet breakfast
Holiday Inn Express Hotel & Suites Memphis Southwind by IHG

Holiday Inn Express Hotel & Suites Memphis Southwind by IHG

Holiday Inn Express Hotel & Suites Memphis Southwind by IHG
3.0 star property
Southwind, 24.3 km from Medical District
8.4 out of 10, Very good, (1004)
"Great stay!!"
United States
Megan
The price is ฿2,172
฿2,482 total
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express Hotel & Suites Memphis Southwind by IHG
Lobby
Drury Inn & Suites Memphis Southaven

Drury Inn & Suites Memphis Southaven

Drury Inn & Suites Memphis Southaven
3.0 star property
20 km from Medical District
9.2 out of 10, Wonderful, (1010)
"Friendly staff, clean room, happy hour food & drink"
United States
Kathleen
The price is ฿3,103
฿3,445 total
includes taxes & fees
2 Jan - 3 Jan 2026
Drury Inn & Suites Memphis Southaven
Room, 2 Queen Beds, Non Smoking | Premium bedding, pillow-top beds, desk, iron/ironing board
La Quinta Inn & Suites by Wyndham Memphis Wolfchase

La Quinta Inn & Suites by Wyndham Memphis Wolfchase

La Quinta Inn & Suites by Wyndham Memphis Wolfchase
3.0 star property
Wolfchase, 24 km from Medical District
8.8 out of 10, Excellent, (1006)
"Staff was friendly, free breakfast was fresh and hot. Coffee at all times"
United States
Teresa
The price is ฿3,139
฿3,790 total
includes taxes & fees
1 Jan - 2 Jan 2026
La Quinta Inn & Suites by Wyndham Memphis Wolfchase
Seasonal outdoor pool
Comfort Inn Memphis Downtown

Comfort Inn Memphis Downtown

Comfort Inn Memphis Downtown
2.5 star property
Downtown Memphis, 1.9 km from Medical District
8.8 out of 10, Excellent, (1016)
"Great hotel "
United States
Andre
The price is ฿2,668
฿3,231 total
includes taxes & fees
4 Jan - 5 Jan 2026
Comfort Inn Memphis Downtown
Terrace/patio
Holiday Inn Hotel & Suites Memphis - Wolfchase Galleria by IHG

Holiday Inn Hotel & Suites Memphis - Wolfchase Galleria by IHG

Holiday Inn Hotel & Suites Memphis - Wolfchase Galleria by IHG
3.0 star property
Wolfchase, 24 km from Medical District
8.8 out of 10, Excellent, (1008)
"Staff is welcome and room is clean and amazing "
United States
Truc
The price is ฿3,135
฿3,784 total
includes taxes & fees
31 Dec - 1 Jan 2026
Holiday Inn Hotel & Suites Memphis - Wolfchase Galleria by IHG
Lobby
Hilton Garden Inn Memphis/Wolfchase Galleria

Hilton Garden Inn Memphis/Wolfchase Galleria

Hilton Garden Inn Memphis/Wolfchase Galleria
3.0 star property
22.1 km from Medical District
8.2 out of 10, Very good, (1005)
"Love that hotel "
United States
Sherkenna
The price is ฿2,602
฿3,152 total
includes taxes & fees
5 Jan - 6 Jan 2026
Hilton Garden Inn Memphis/Wolfchase Galleria
View from property
Fairfield Inn & Suites By Marriott Memphis Germantown

Fairfield Inn & Suites By Marriott Memphis Germantown

Fairfield Inn & Suites By Marriott Memphis Germantown
2.5 star property
27.1 km from Medical District
8.2 out of 10, Very good, (1003)
"Warm breakfast Clean pool and hot tub Nice parking "
United States
Glenda
The price is ฿3,414
฿4,088 total
includes taxes & fees
2 Jan - 3 Jan 2026
Fairfield Inn & Suites By Marriott Memphis Germantown
Food and drink
Hu. Hotel

Hu. Hotel

Hu. Hotel
3.5 star property
Downtown Memphis, 1.9 km from Medical District
8.4 out of 10, Very good, (1647)
"Friendly staff, clean rooms, perfect location"
United States
Billy
The price is ฿2,722
฿3,376 total
includes taxes & fees
8 Jan - 9 Jan 2026
Hu. Hotel
Exterior
Four Points by Sheraton Memphis Southwind

Four Points by Sheraton Memphis Southwind

Four Points by Sheraton Memphis Southwind
3.0 star property
Southwind, 24.2 km from Medical District
8.2 out of 10, Very good, (1001)
"Clean rooms, great breakfast, and super friendly staff."
United States
Kameilah
The price is ฿2,538
฿2,900 total
includes taxes & fees
4 Jan - 5 Jan 2026
Four Points by Sheraton Memphis Southwind
Free daily buffet breakfast
Hyatt Place Memphis Primacy Park

Hyatt Place Memphis Primacy Park

Hyatt Place Memphis Primacy Park
3.0 star property
16.2 km from Medical District
7.8 out of 10, Good, (1003)
"Great service and breakfast "
United States
Chase
The price is ฿2,886
฿3,490 total
includes taxes & fees
11 Jan - 12 Jan 2026
Hyatt Place Memphis Primacy Park
Lobby lounge
Memphis Vitality Hotel

Memphis Vitality Hotel

Memphis Vitality Hotel
4.0 star property
13.8 km from Medical District
8.4 out of 10, Very good, (1233)
"Staff was amazing. Room was clean. We enjoyed our stay."
United States
Johnathon
The price is ฿2,704
฿3,273 total
includes taxes & fees
30 Dec - 31 Dec
Memphis Vitality Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Medical District

Find the best Medical District areas for the activities you enjoy most.

Downtown Memphis

Downtown Memphis is a destination visitors seek out for its ample dining options, fascinating museums and great live music. You might also want to check out attractions like Statue of Elvis or Orpheum Theatre while you're exploring the neighbourhood.

East Memphis

Travellers to East Memphis praise its popular shops. If you've got some more time to explore, be sure to stop by Theatre Memphis and Memphis Botanic Garden.

Midtown

Theatres, live music and museums are some highlights of Midtown. Make a stop by Minglewood Hall or Memphis Brooks Museum of Art while you're exploring.

Whitehaven

The ample dining options and great live music are top of the list for many visitors to Whitehaven. A stop by Graceland or Southland Mall might round out your trip.

North Memphis

Visitors to North Memphis like its bars and churches, and Burkle Estate is a sight worth a stop.

Top Medical District Hotel Reviews

Memphis Vitality Hotel

Memphis Vitality Hotel

10/10 Excellent
"Staff was amazing. Room was clean. We enjoyed our stay."
Johnathon 3-night trip
Posted 3 days ago
Memphis Vitality Hotel

Frequently asked questions

What's it like in Medical District?
Travellers will be sure to enjoy their time in Memphis's Medical District neighbourhood. Are you looking for Medical District travel tips? Make sure that you visit Sun Studio and Hunt-Phelan Home while you're in the neighbourhood.
What's the best accommodation in Medical District?
Based on Expedia customer reviews, Capital O Kings Inn is the highest ranked property in Medical District. This hotel offers free parking and free WiFi. Another favourite option in the neighbourhood is Motel 6 Memphis, TN - Downtown.
How many hotels can I expect to find in Medical District?
When you want to put your feet up after a day of exploring the sights in Memphis, you can choose from 18 Expedia hotels and other accommodation options in Medical District.
If I need to cancel my hotel reservation in Medical District, will I receive a refund?
Yes! Most hotel bookings are refundable if you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, you might be able to cancel it and receive a refund within 24 hours of booking. Add dates, click "Search", then use the "fully refundable" filter to get the best deals available in Medical District.
What are the top things to see and do in Medical District?
Some landmarks in Medical District that you won't want to miss include Sun Studio, Hunt-Phelan Home and NAACP Memphis. Woodruff-Fontaine House and Mallory-Neely House are also worth a visit when you're out sightseeing in Memphis.