Zona 21 Travel Guide

Guatemala City


Things to do


Top hotels in Zona 21

Barceló Guatemala City

Barceló Guatemala City

4.5 out of 5
7 Avenida 15-45, Zona 9 Guatemala City Guatemala
The price is ฿3,181 per night from 28 Sept to 29 Sept
฿3,181
฿3,881 total
28 Sept - 29 Sept
includes taxes & fees
Stay at this luxury hotel in Guatemala City. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the breakfast and the pool in their reviews. ...
9.2/10 Wonderful! (3,299 reviews)
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Reviewed on 23 Sept 2026

Barceló Guatemala City
Hotel Museo Spa Casa Santo Domingo

Hotel Museo Spa Casa Santo Domingo

4.5 out of 5
3a Calle Oriente No 28 A Antigua Guatemala Sacatepequez
The price is ฿7,883 per night from 29 Sept to 30 Sept
฿7,883
฿10,021 total
29 Sept - 30 Sept
includes taxes & fees
Stay at this luxury hotel in Antigua Guatemala. Enjoy free parking, a full-service spa and 2 restaurants. Our guests praise the helpful staff and the property ...
9.4/10 Exceptional! (1,159 reviews)
"Todo súper bien como siempre"

Reviewed on 23 Sept 2026

Hotel Museo Spa Casa Santo Domingo
Wyndham Garden Guatemala City

Wyndham Garden Guatemala City

4 out of 5
1a Avenida 12-46 Zona 10 Guatemala City Guatemala
The price is ฿3,551 per night from 17 Oct to 18 Oct
฿3,551
฿4,333 total
17 Oct - 18 Oct
includes taxes & fees
Stay at this business-friendly hotel in Guatemala City. Enjoy free breakfast, free Wi-Fi and room service. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,923 reviews)
"We got very sick after our stay the room was not properly disinfected"

Reviewed on 23 Sept 2026

Wyndham Garden Guatemala City
Hotel Camino Real Antigua

Hotel Camino Real Antigua

4 out of 5
7a Calle Poniente 33B Antigua Guatemala Sacatepequez
The price is ฿6,260 per night from 28 Sept to 29 Sept
฿6,260
฿8,465 total
28 Sept - 29 Sept
includes taxes & fees
Stay at this spa hotel in Antigua Guatemala. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the helpful staff and the property condition ...
9.6/10 Exceptional! (1,001 reviews)
"Excelente servicio y las instalaciones muy limpias y ordenadas"

Reviewed on 24 Sept 2026

Hotel Camino Real Antigua
Adriatika Hotel & Residence

Adriatika Hotel & Residence

4.5 out of 5
4 av 20-44 Zona 14 Guatemala City Guatemala
The price is ฿3,875 per night from 25 Sept to 26 Sept
฿3,875
฿4,727 total
25 Sept - 26 Sept
includes taxes & fees
Stay at this luxury hotel in Guatemala City. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms ...
9.6/10 Exceptional! (1,005 reviews)
"El desayuno estuvo muy rico"

Reviewed on 24 Sept 2026

Adriatika Hotel & Residence
Hotel Biltmore Guatemala

Hotel Biltmore Guatemala

3.5 out of 5
15 Calle 0-31, Zona 10 Guatemala City Guatemala
The price is ฿2,921 per night from 9 Oct to 10 Oct
฿2,921
฿3,564 total
9 Oct - 10 Oct
includes taxes & fees
Stay at this business-friendly hotel in Guatemala City. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff in their ...
Hotel Biltmore Guatemala
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Zona 21

Find the best Zona 21 areas for the activities you enjoy most.

Zona 10

Zona 10 is known for its abundant dining options, and you can plan a trip to Oakland Mall and Plaza Fontabella Shopping Center while you're in town.

Zona 1

Zona 1 is noteworthy for its historical sites, and you can make a stop at top attractions like Catedral Metropolitana and Palacio Nacional de la Cultura.

Zona 13

Zona 13 is noteworthy for its gardens, and you can make a stop at top attractions like Avenida Las Américas and La Aurora Zoo.

Zona 9

Travellers come to Zona 9 for its abundant dining options, and you can see top attractions like Avenida La Reforma and Torre del Reformador while you're in town.

Zona 4

Visitors to Zona 4 enjoy its restaurants, and if you want to do some exploring, Avenida La Reforma is worth a stop.



Zona 21 Travel Guide