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Our top choices for Duke Homestead hotels

Hampton Inn & Suites Durham University Medical Center

Hampton Inn & Suites Durham University Medical Center
2.5 star property
3.1 km from Duke Homestead
9.6 out of 10, Exceptional, (389)
"Great breakfast, clean rooms and beds "
United States
Fabiola B
The price is ฿3,277
฿3,719 total
includes taxes & fees
26 Dec - 27 Dec
Hampton Inn & Suites Durham University Medical Center

Holiday Inn Express Durham by IHG

Holiday Inn Express Durham by IHG
2.5 star property
1.1 km from Duke Homestead
8.8 out of 10, Excellent, (949)
"Room was great"
United States
Barbara
The price is ฿2,921
฿3,315 total
includes taxes & fees
28 Dec - 29 Dec
Holiday Inn Express Durham by IHG

Hampton Inn & Suites Durham/North I-85

Hampton Inn & Suites Durham/North I-85
2.5 star property
2.5 km from Duke Homestead
9.0 out of 10, Wonderful, (1000)
"Nice place to stay and close to everything. "
United States
Christy
The price is ฿3,277
฿3,719 total
includes taxes & fees
27 Dec - 28 Dec
Hampton Inn & Suites Durham/North I-85

Comfort Inn & Suites Durham near Duke University

Comfort Inn & Suites Durham near Duke University
2.5 star property
Croasdaile Farm Master, 1.4 km from Duke Homestead
8.6 out of 10, Excellent, (1001)
"Loved our stay"
United States
Brian
The price is ฿3,011
฿3,417 total
includes taxes & fees
28 Dec - 29 Dec
Comfort Inn & Suites Durham near Duke University

Courtyard Durham Near Duke University/Downtown

Courtyard Durham Near Duke University/Downtown
3.0 star property
Croasdaile Farm Master, 1.5 km from Duke Homestead
8.2 out of 10, Very good, (1001)
"Great place "
United States
Silvia
The price is ฿3,346
฿3,798 total
includes taxes & fees
19 Dec - 20 Dec
Courtyard Durham Near Duke University/Downtown

Red Roof Inn Durham - Duke Univ Medical Center

Red Roof Inn Durham - Duke Univ Medical Center
2.0 star property
0.8 km from Duke Homestead
6.8 out of 10, (1001)
"Good motel...clean, easy acess "
United States
Howard
The price is ฿1,843
฿2,146 total
includes taxes & fees
21 Dec - 22 Dec
Red Roof Inn Durham - Duke Univ Medical Center

Royal Inn

Royal Inn
2.0 star property
2.9 km from Duke Homestead
5.8 out of 10, (1028)
"It was ok"
United States
Precious
The price is ฿2,540
฿2,883 total
includes taxes & fees
12 Dec - 13 Dec
Royal Inn

Super 8 by Wyndham Durham/University Area NC

Super 8 by Wyndham Durham/University Area NC
2.0 star property
1.2 km from Duke Homestead
5.0 out of 10, (344)
"The environment was not pleasant "
United States
Denise
The price is ฿2,024
฿2,297 total
includes taxes & fees
26 Dec - 27 Dec
Super 8 by Wyndham Durham/University Area NC

Hilton Garden Inn Durham/University Medical Center

Hilton Garden Inn Durham/University Medical Center
3.0 star property
9th Street District, 3.4 km from Duke Homestead
9.2 out of 10, Wonderful, (999)
"Clean rooms, nice staff. Clean hotel. Ample parking. "
United States
Emana
The price is ฿2,518
฿2,858 total
includes taxes & fees
19 Dec - 20 Dec
Hilton Garden Inn Durham/University Medical Center

AC Hotel Durham

AC Hotel Durham
3.0 star property
4 km from Duke Homestead
9.0 out of 10, Wonderful, (609)
"Room was very clean, staff very helpful and nice. "
United States
Tia
The price is ฿3,751
฿4,258 total
includes taxes & fees
18 Dec - 19 Dec
AC Hotel Durham

University Inn Durham next to Duke University Medical Center

University Inn Durham next to Duke University Medical Center
2.0 star property
3.3 km from Duke Homestead
8.8 out of 10, Excellent, (1001)
"The staff was great and very friendly! Everything was very clean! Very nice stay and definitely reasonable rates!"
United States
Doug
The price is ฿3,400
฿3,859 total
includes taxes & fees
24 Dec - 25 Dec
University Inn Durham next to Duke University Medical Center

Residence Inn Durham McPherson/Duke University Medical Cntr

Residence Inn Durham McPherson/Duke University Medical Cntr
3.0 star property
Trinity Park, 4 km from Duke Homestead
9.2 out of 10, Wonderful, (459)
"Hotel was great - very friendly staff."
United States
Lisa
The price is ฿4,261
฿4,836 total
includes taxes & fees
11 Jan - 12 Jan 2026
Residence Inn Durham McPherson/Duke University Medical Cntr

JB Duke Hotel

JB Duke Hotel
4.0 star property
5 km from Duke Homestead
9.4 out of 10, Exceptional, (536)
"Great service at the front desk and bar. The environment was also very nice. "
United States
Logan David
The price is ฿4,726
฿5,364 total
includes taxes & fees
25 Dec - 26 Dec
JB Duke Hotel

Washington Duke Inn & Golf Club

Washington Duke Inn & Golf Club
4.0 star property
5.4 km from Duke Homestead
9.4 out of 10, Exceptional, (1003)
"Everything was fabulous. Very relaxing and enjoyable"
United States
William
The price is ฿5,080
฿5,766 total
includes taxes & fees
18 Dec - 19 Dec
Washington Duke Inn & Golf Club

Hilton Durham near Duke University

Hilton Durham near Duke University
3.5 star property
3.5 km from Duke Homestead
8.4 out of 10, Very good, (1002)
"Great stay"
United States
Daniel
The price is ฿3,098
฿3,516 total
includes taxes & fees
24 Dec - 25 Dec
Hilton Durham near Duke University

SpringHill Suites by Marriott Durham City View

SpringHill Suites by Marriott Durham City View
3.5 star property
5.6 km from Duke Homestead
9.2 out of 10, Wonderful, (451)
"Great room, showers amazing, great staff. "
United States
Micah
The price is ฿3,270
฿3,712 total
includes taxes & fees
4 Jan - 5 Jan 2026
SpringHill Suites by Marriott Durham City View

The Lodge at Duke Medical Center

The Lodge at Duke Medical Center
3.0 star property
3.4 km from Duke Homestead
8.4 out of 10, Very good, (1002)
"Older property but very convenient and clean for our quick trip. "
United States
Stacie
The price is ฿4,096
฿4,649 total
includes taxes & fees
14 Dec - 15 Dec
The Lodge at Duke Medical Center

The Durham Hotel

The Durham Hotel
4.0 star property
Downtown Durham, 4.8 km from Duke Homestead
9.0 out of 10, Wonderful, (638)
"Perfect place to stay for an easy walk to see a show at the charming Carolina Theater. Food, service and atmosphere were outstanding. "
United States
Jo
The price is ฿5,906
฿6,703 total
includes taxes & fees
16 Dec - 17 Dec
The Durham Hotel

Aloft Durham Downtown

Aloft Durham Downtown
3.0 star property
American Tobacco District, 5.1 km from Duke Homestead
9.0 out of 10, Wonderful, (730)
"Very friendly staff, very clean and convenient location"
United States
Robert
The price is ฿6,191
฿7,027 total
includes taxes & fees
28 Dec - 29 Dec
Aloft Durham Downtown

Durham Marriott City Center

Durham Marriott City Center
3.5 star property
Downtown Durham, 4.8 km from Duke Homestead
8.8 out of 10, Excellent, (822)
"The room was clean. The staff was very helpful and the food was good. "
United States
Tia
The price is ฿4,255
฿4,829 total
includes taxes & fees
24 Dec - 25 Dec
Durham Marriott City Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Duke Homestead Hotel Reviews

Hotels near other Duke Homestead attractions

Frequently asked questions

What's the area like around Duke Homestead?
Duke Homestead is located in a family-friendly area of Durham known for its stunning cathedral. If you're looking for a convenient place to stay, take a look at the 40 hotels and other accommodation options you'll find within a mile.
What's the best hotel to stay near Duke Homestead?
Comfort Inn & Suites Durham near Duke University is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and free parking. It's located just a short 0.9 mi (1.4 km) from Duke Homestead. Other good choices within a short distance include Red Roof Inn Durham - Duke Univ Medical Center and Holiday Inn Express Durham by IHG.
How many hotels should I expect to find close to Duke Homestead?
Expedia has 40 hotels and other accommodation options within a mile from Duke Homestead.
If I need to cancel the hotel reservation for my stay near Duke Homestead, will I receive a refund?
Yes, you'll find most hotel room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of booking. Add your dates and click on "Search", then you can filter by "fully refundable" to get the top deals on offer near Duke Homestead.
What can I see and do near Duke Homestead?
Study the collections at Museum of Life and Science, Nasher Museum of Art at Duke University or Bennett Place. Explore notable local landmarks like Cameron Indoor Stadium, Wallace Wade Stadium and American Tobacco Campus. You can watch performances at Carolina Theatre, Durham Performing Arts Center and Manbites Dog Theater if you're interested in local theatre.