The Best Hotels Closest to Museum of Life and Science in Raleigh - 2026 Updated Prices

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Our top choices for Museum of Life and Science hotels

A breakfast area with a chalkboard menu, a sign indicating breakfast starts here, and a variety of food items like waffles, oatmeal, and fruits.

A narrow hallway with shelves stocked with snacks and beverages, leading to a room with a desk and chair.

A large indoor swimming pool with clear blue water, surrounded by beige tiled flooring and walls, with large windows allowing natural light.

A hotel room with a bed, a desk with a chair, a flat-screen TV, a microwave, and a mirror.

1. Hampton Inn & Suites Durham/North I-85

1.4 km from Museum of Life and Science

Mark

฿3,970

฿4,506 total

includes taxes & fees

4 Oct - 5 Oct

A hotel room with two beds, a flat-screen TV, a wooden headboard, and a carpeted floor.

A Holiday Inn Express hotel with a modern design, featuring a prominent sign, multiple windows, and a well-lit entrance.

A breakfast buffet with a bakery section, a coffee station, and a sign indicating the availability of breakfast.

A coffee station with two coffee machines, a coffee press, and various coffee-related items on a counter.

2. Holiday Inn Express Durham by IHG

2.2 km from Museum of Life and Science

Kimberly R

฿3,673

฿4,169 total

includes taxes & fees

4 Oct - 5 Oct

A hotel room with a bed, a desk, a chair, a small table, a coffee machine, and a trash bin.

A swimming pool with lounge chairs and umbrellas, surrounded by a building with a clear sky.

A reception area with a wooden reception desk, blue seating, a flat-screen TV, and a stone accent wall.

A restaurant with a large ice dispenser, wooden paneling, and red cushioned booths.

3. Comfort Inn & Suites Durham near Duke University

Croasdaile Farm Master, 3.2 km from Museum of Life and Science

BRIAN

฿2,838

฿3,221 total

includes taxes & fees

18 Oct - 19 Oct

A hotel room with a bed, a desk, a chair, a television, a microwave, a refrigerator, and a mirror.

A spacious hallway with wooden flooring, white walls, and multiple windows with blinds. There are two white chairs and a small table with a basket.

A motel with a red and white sign, multiple balconies, and a parking lot.

A vending machine area with Pepsi and other beverage options, including a selection of juices and sodas.

4. Red Roof Inn Durham - Duke Univ Medical Center

2.2 km from Museum of Life and Science

Luis

฿2,098

฿2,439 total

includes taxes & fees

11 Oct - 12 Oct

A stone fire pit surrounded by striped chairs and tables in an outdoor lounge area with a view of a building in the background.

A modern dining area with a long table, multiple chairs, and a sofa with red ottomans.

A modern hotel lobby with a reception desk, seating area, and a cityscape mural on the wall.

A Hampton Inn & Suites hotel with a modern facade, multiple windows, and a parking lot.

5. Hampton Inn & Suites Durham University Medical Center

4.8 km from Museum of Life and Science

Donna

฿4,353

฿4,941 total

includes taxes & fees

4 Oct - 5 Oct

An outdoor patio area with round tables and chairs, large umbrellas, and a glass door entrance.

A hotel room with two beds, a desk, a chair, a sofa, and a TV.

A modern living room with a fireplace, two sofas, a coffee table, and a TV mounted on the wall.

A modern restaurant with round tables and yellow chairs, a bar area, and a 'Hello Fall' sign.

6. Fairfield by Marriott Inn & Suites Durham

17.3 km from Museum of Life and Science

Yolanda

฿3,756

฿4,263 total

includes taxes & fees

22 Oct - 23 Oct

A brick pathway flanked by neatly trimmed hedges leading to a building with a red facade and a grey roof.

A spacious lobby with a long corridor, comfortable seating areas, and large windows providing natural light.

An outdoor dining area with tables set for four, surrounded by a brick pathway and lush greenery.

A modern living room with two sofas facing a glass coffee table, a large window with curtains, and a brick wall.

7. Rizzo Center, a Destination by Hyatt Hotel

16.3 km from Museum of Life and Science

Dale

฿6,510

฿7,389 total

includes taxes & fees

11 Oct - 12 Oct

A modern living room with a pool table, a sofa, and a dining area.

An outdoor dining area with tables and chairs, large windows, and a view of greenery.

A bar area with multiple shelves of bottles, glasses, and a bar counter.

8. The Westin Raleigh-Durham Airport

17.5 km from Museum of Life and Science

Dina

฿7,196

฿8,150 total

includes taxes & fees

4 Oct - 5 Oct

A breakfast counter with various food items and a sign that reads 'TOP IT BREAKFAST'.

A hotel reception area with a wooden reception desk, large windows, and a circular ceiling design.

An outdoor seating area with a blue sofa, orange chairs, and a table.

A modern hotel lobby with a central counter, a refrigerated display case, and a seating area with a sofa.

9. Tru by Hilton Raleigh Durham Airport

19.7 km from Museum of Life and Science

Trenton

฿3,532

฿4,000 total

includes taxes & fees

18 Oct - 19 Oct

A hotel entrance with a stone facade, large wooden doors, and a view into the interior.

A hotel with a stone lion statue, a covered entrance, and a landscaped garden.

A dining area with a chandelier, tables, chairs, and a Christmas tree.

A person performing a yoga pose outdoors with trees and a golf course in the background.

10. Washington Duke Inn & Golf Club

5.9 km from Museum of Life and Science

Lowell

฿8,013

฿9,095 total

includes taxes & fees

27 Sept - 28 Sept

An outdoor seating area with wicker furniture and a stone fire pit.

An indoor swimming pool with clear water, a lifeguard chair, and a sign indicating no diving.

A hotel lobby with a sofa, chairs, a table, and a large window offering a view of the building.

A modern hotel lobby with seating areas, large windows, and a dining section.

11. Residence Inn Raleigh-Durham Airport/Brier Creek

15.9 km from Museum of Life and Science

Janet

฿4,654

฿5,271 total

includes taxes & fees

4 Oct - 5 Oct

An indoor swimming pool with clear water, a no diving sign, and a seating area with chairs and tables.

A modern hotel lobby with a long dining table, multiple chairs, a sofa, and a bar area.

A modern kitchen with built-in shelves, a glass backsplash, and a variety of kitchenware.

A modern hotel lobby with a reception desk, several chairs, a large monitor, and pendant lighting.

12. Hyatt House Raleigh / RDU / Brier Creek

17.1 km from Museum of Life and Science

Zashia

฿3,940

฿4,462 total

includes taxes & fees

4 Oct - 5 Oct

A swimming pool with lounge chairs and a wooden fence.

A multi-story hotel with a modern design, featuring a prominent entrance with a glass canopy and an American flag.

A modern bar area with a refrigerated display, wooden bar counter, and seating.

A hotel room with a bed, a sofa, a desk with a chair, a television, and a painting on the wall.

13. Hyatt Place Durham Southpoint

15.3 km from Museum of Life and Science

Andres

฿4,507

฿5,116 total

includes taxes & fees

11 Oct - 12 Oct

A spacious lobby with high ceilings, a central fountain, and seating areas.

A spacious lobby with a curved seating area, large windows, and a modern chandelier.

A modern bedroom with a large bed, a fireplace, a walk-in closet, and a bathroom with a round mirror and vanity.

A bar area with multiple liquor cabinets and hanging pendant lights.

14. Embassy Suites by Hilton Raleigh Durham Airport Brier Creek

17.5 km from Museum of Life and Science

Darren C.

฿5,325

฿6,030 total

includes taxes & fees

25 Oct - 26 Oct

An outdoor patio with a stone fire pit, seating, and a covered area.

A multi-story hotel with a 'TOWNEPLACE' sign, a covered entrance, and a parking area with cars.

A hotel room with a bed, a desk, and a chair. There is a door and a wall-mounted lamp.

A reception area with a wooden counter, a 'HELLO Morrisville' sign, a 'PINCH' sign above a snack display, and a 'Manager on Duty' sign.

15. Towneplace Suites By Marriott Raleigh-Durham Airport/Morrisville

19.7 km from Museum of Life and Science

Anthony

฿3,314

฿3,753 total

includes taxes & fees

27 Sept - 28 Sept

A lobby with a green sofa, yellow chairs, a coffee table with drinks, and a window with plants.

An indoor swimming pool with clear glass walls, a tiled floor, and a seating area with chairs and a table.

A business center with wooden paneling, multiple workstations, and framed artwork on the walls.

A Hilton Garden Inn hotel with a modern design, featuring a large entrance and a parking area with a delivery van.

16. Hilton Garden Inn Durham/University Medical Center

9th Street District, 3.3 km from Museum of Life and Science

Hal

฿4,901

฿5,562 total

includes taxes & fees

11 Oct - 12 Oct

A modern hotel with a prominent entrance, multiple floors, and a balcony on the second floor.

A modern dining area with wooden tables and chairs, large windows, and geometric pendant lighting.

An outdoor patio with a fire feature, seating, and a building with large windows.

A modern hotel room with a bed, a desk, a chair, a small seating area, and a kitchenette.

17. SpringHill Suites by Marriott Durham City View

4.6 km from Museum of Life and Science

Taurean

฿4,427

฿5,025 total

includes taxes & fees

18 Oct - 19 Oct

An outdoor patio with wicker furniture, a stone fire pit, and a brick building in the background.

A spacious lobby with a reception desk, seating area, and a beverage kiosk.

A hotel room with two beds, a desk, a TV, and a sofa.

A gym with treadmills, elliptical machines, a bench press, and a blue balance board.

18. Residence Inn Durham McPherson/Duke University Medical Cntr

Trinity Park, 3.3 km from Museum of Life and Science

Shelly

฿5,553

฿6,303 total

includes taxes & fees

29 Sept - 30 Sept

A hotel room with two beds, a desk, a chair, a TV, and a bathroom.

A reception area with two wooden reception desks, a potted plant, and a computer on the wall.

A hotel room with a sofa, a small table, a desk, a chair, a TV, and a window with curtains.

19. Courtyard Raleigh-Durham Airport/Brier Creek

15.9 km from Museum of Life and Science

eidy

฿4,473

฿5,066 total

includes taxes & fees

18 Oct - 19 Oct

A lobby with a bar area, seating, and a wine display.

A bar area with seating, a bar counter, and a menu board.

A covered outdoor dining area with tables set for a meal, surrounded by chairs, and overlooking a garden with blooming trees.

A large, white, two-story building with a prominent sign reading "DoubleTree".

20. DoubleTree Raleigh Durham Airport at Research Triangle Park

16.9 km from Museum of Life and Science

Xueqin

฿3,805

฿4,319 total

includes taxes & fees

22 Oct - 23 Oct

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Compare popular hotels close to Museum of Life and Science

Property	Property class	Guest rating
Hampton Inn & Suites Durham/North I-85	9.0 Wonderful 1,005 reviews	View
Holiday Inn Express Durham by IHG	8.8 Excellent 1,003 reviews	View
Comfort Inn & Suites Durham near Duke University	8.6 Excellent 1,152 reviews	View
Red Roof Inn Durham - Duke Univ Medical Center	6.8 1,001 reviews	View
Hampton Inn & Suites Durham University Medical Center	9.6 Exceptional 561 reviews	View

Top Museum of Life and Science Hotel Reviews

The Lodge at Duke Medical Center

10/10 Excellent

"Great staff. Clean and convenient location!"

Comfort Inn & Suites Durham near Duke University

10/10 Excellent

"Cleanliness"

University Inn Durham next to Duke University Medical Center

10/10 Excellent

"Quiet, clean, near Duke Hospitals, convenient to most of Durham"

Hilton Durham near Duke University

8/10 Good

"the shower control was very difficult to operate....takes a lot strength to turn! Room 202"

Courtyard Durham Near Duke University/Downtown

8/10 Good

"Great Location and staff was helpful"

Hampton Inn & Suites Durham/North I-85

10/10 Excellent

"The Hampton was recently remodeled and is a fantastic facility. So enjoy being there. The front desk staff and breakfast were very helpful."

Hilton Garden Inn Durham/University Medical Center

10/10 Excellent

"Nice clean room in a great location for fine dining. We will definitely stay here again when in Durham."

Other attractions near Museum of Life and Science

Brightleaf Square

9.6/10 (8 reviews)

You can do some window-shopping at Brightleaf Square during your visit to Durham. Discover the lively festivals and stunning cathedral in this family-friendly area.

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Vietnam Veterans Living Memorial

You can find out about the history of Durham with a trip to Vietnam Veterans Living Memorial. Attend a sporting event or visit the stunning cathedral in this family-friendly area.

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Northgate Mall

8.2/10 (60 reviews)

You can search for that perfect souvenir at Northgate Mall during your stay in Durham. Experience the lively festivals or attend a sporting event in this family-friendly area.

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Duke Homestead

Learn about the local history of Durham when you take a trip to Duke Homestead. Attend a sporting event or visit the stunning cathedral in this family-friendly area.

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Fullsteam Brewery

7.4/10 (3 reviews)

You can take time to visit Fullsteam Brewery during your travels to Durham. Experience the lively festivals or attend a sporting event in this family-friendly area.

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Durham Convention Center

8.2/10 (118 reviews)

Learn about the events happening in Durham Convention Center during your trip to Durham. Discover the entertainment choices and stunning cathedral in this family-friendly area.

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African American Dance Ensemble

8.8/10 (3 reviews)

You can enjoy some culture when you stop by African American Dance Ensemble in Durham.

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Carolina Theatre

8.2/10 (220 reviews)

You can get tickets for a performance at Carolina Theatre during your stay in Durham. Experience the area's entertainment choices or attend a sporting event.

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Frequently asked questions

What's the area like around Museum of Life and Science?

Museum of Life and Science is located in an area of Durham known for its stunning cathedral. If you're looking for a convenient place to stay, take a look at the 10 hotels and other accommodation options you'll find within a mile.

What's the best hotel to stay near Museum of Life and Science?

Hampton Inn & Suites Durham/North I-85 is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an indoor pool. It's located just a short 0.8 mi (1.4 km) from Museum of Life and Science. Other good options within 5 miles include Holiday Inn Express Durham by IHG and Red Roof Inn Durham - Duke Univ Medical Center.

How many hotels can I expect to find close to Museum of Life and Science?

Expedia has 10 hotels and other accommodation options within a mile from Museum of Life and Science.

If I need to cancel the hotel reservation for my stay near Museum of Life and Science, will I receive a refund?

Yes, the majority of hotel room reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of your booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to get the best deals near Museum of Life and Science.

What can I see and do near Museum of Life and Science?

You'll want to browse the exhibits at Nasher Museum of Art at Duke University and Bennett Place. Explore landmarks like American Tobacco Campus, Cameron Indoor Stadium and Wallace Wade Stadium. You can enjoy live performances at Carolina Theatre and Common Ground Theatre.

Search Hotels Near Museum of Life and Science, Raleigh

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Our top choices for Museum of Life and Science hotels

1. Hampton Inn & Suites Durham/North I-85

2. Holiday Inn Express Durham by IHG

3. Comfort Inn & Suites Durham near Duke University

4. Red Roof Inn Durham - Duke Univ Medical Center

5. Hampton Inn & Suites Durham University Medical Center

6. Fairfield by Marriott Inn & Suites Durham

7. Rizzo Center, a Destination by Hyatt Hotel

8. The Westin Raleigh-Durham Airport

9. Tru by Hilton Raleigh Durham Airport

10. Washington Duke Inn & Golf Club

11. Residence Inn Raleigh-Durham Airport/Brier Creek

12. Hyatt House Raleigh / RDU / Brier Creek

13. Hyatt Place Durham Southpoint

14. Embassy Suites by Hilton Raleigh Durham Airport Brier Creek

15. Towneplace Suites By Marriott Raleigh-Durham Airport/Morrisville

16. Hilton Garden Inn Durham/University Medical Center

17. SpringHill Suites by Marriott Durham City View

18. Residence Inn Durham McPherson/Duke University Medical Cntr

19. Courtyard Raleigh-Durham Airport/Brier Creek

20. DoubleTree Raleigh Durham Airport at Research Triangle Park

Compare popular hotels close to Museum of Life and Science

Top Museum of Life and Science Hotel Reviews

The Lodge at Duke Medical Center

Comfort Inn & Suites Durham near Duke University

University Inn Durham next to Duke University Medical Center

Hilton Durham near Duke University

Courtyard Durham Near Duke University/Downtown

Hampton Inn & Suites Durham/North I-85

Hilton Garden Inn Durham/University Medical Center

Other attractions near Museum of Life and Science

Brightleaf Square

Vietnam Veterans Living Memorial

Northgate Mall

Duke Homestead

Fullsteam Brewery

Durham Convention Center

African American Dance Ensemble

Carolina Theatre

Frequently asked questions