Uptown Travel Guide
Collinsville
Stay near popular Uptown attractions
Things to do
St. Louis & Gateway Arch NP Self Guided Walk & Drive Audio Tour
฿557
per traveller
St. Louis Ghost Tour: Sinister Sins & Shadows
฿787
per adult
100% of travellers recommend
Gateway Arch National Park Self Guided Audio Walking Tour
฿492
per traveller
Self Guided Walk & Drive Audio Tour St. Louis & Gateway Arch NP
฿492
per traveller
Top hotels in Uptown
Hyatt Regency St. Louis at The Arch
315 Chestnut St St. Louis MO
The price is ฿5,005 per night from 4 Oct to 5 Oct
฿5,005
฿5,902 total
4 Oct - 5 Oct
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, 3 restaurants and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (4,243 reviews)
"First I will say that the hotel staff was fantastic. They were very friendly & very helpful considering it was an absolute zoo due to the AC/DC concert going on at The Dome. Our room was okay, but the bathroom wasn't very clean & didn't have an exhaust fan. We were supposed to have a king room but ..."
Reviewed on 11 Sept 2026
Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
The price is ฿3,150 per night from 11 Oct to 12 Oct
฿3,150
฿3,678 total
11 Oct - 12 Oct
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the pool ...
8.8/10 Excellent! (3,380 reviews)
"Free breakfast Free parking Pool Fridge Microwave"
Reviewed on 10 Sept 2026
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
3550 Samuel Sheppard Drive St. Louis MO
The price is ฿4,155 per night from 2 Oct to 3 Oct
฿4,155
฿4,900 total
2 Oct - 3 Oct
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, a rooftop terrace and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.8/10 Excellent! (1,159 reviews)
"unique rooftop restaurant"
Reviewed on 10 Sept 2026
Drury Plaza Hotel St. Louis at the Arch
2 South 4th Street St. Louis MO
The price is ฿4,442 per night from 4 Oct to 5 Oct
฿4,442
฿5,194 total
4 Oct - 5 Oct
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and 2 hot tubs. Our guests praise the breakfast and the pool in their reviews. ...
9.6/10 Exceptional! (3,731 reviews)
"Location fit my needs perfectly. The entire staff was excellent. Will definitely stay here when in St. Louis"
Reviewed on 10 Sept 2026
21C Museum Hotel St Louis
1528 Locust street St. Louis MO
The price is ฿4,759 per night from 4 Oct to 5 Oct
฿4,759
฿5,730 total
4 Oct - 5 Oct
includes taxes & fees
Stay at this luxury hotel in St. Louis. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the pool and the restaurant in their reviews. ...
Home2 Suites by Hilton St. Louis Downtown
1221 Locus Street St. Louis MO
The price is ฿3,211 per night from 20 Sept to 21 Sept
฿3,211
฿3,755 total
20 Sept - 21 Sept
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, valet parking (surcharge) and a 24-hour front desk. Our guests praise the helpful staff ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Uptown
Find the best Uptown areas for the activities you enjoy most.
Eastport
While visiting Eastport, you might make a stop by sights like Gateway Conference Center and Splash City Family Waterpark.
Mulberry Hills
Though Mulberry Hills may not have many top sights, you can venture to the surrounding area to see attractions like Gateway Conference Center and FanDuel Sportsbook and Horse Racing.
Historic Downtown Collinsville
Though Historic Downtown Collinsville may not have many top sights, you can venture to the surrounding area to see attractions like World's Largest Catsup Bottle and Gateway Conference Center.
