Uptown Travel Guide
Collinsville
Stay near popular Uptown attractions
Things to do
St. Louis Ghost Tour: Sinister Sins & Shadows
฿801
per adult
100% of travellers recommend
St. Louis & Gateway Arch NP Self Guided Walk & Drive Audio Tour
฿567
per traveller
Self Guided Walk & Drive Audio Tour St. Louis & Gateway Arch NP
฿500
per traveller
Gateway Arch National Park Self Guided Audio Walking Tour
฿500
per traveller
Top hotels in Uptown
Drury Plaza Hotel St. Louis at the Arch
2 South 4th Street St. Louis MO
Fully refundableReserve now, pay when you stay
The price is ฿4,864 per night from 9 Nov to 10 Nov
฿4,864
฿5,687 total
9 Nov - 10 Nov
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and 2 hot tubs. Our guests praise the breakfast and the pool in their reviews. ...
9.6/10 Exceptional! (3,816 reviews)
"Very nice the separate bedroom from the living area was wonderful. This is an old historic building that has many unique features. The buffet breakfast and cocktail hour hors d’oeuvres was wonderful. It was great to just come in from a day of sightseeing and have a refreshing drink and food to eat ..."
Reviewed on 1 Nov 2026
Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue St. Louis MO
The price is ฿3,551 per night from 22 Nov to 23 Nov
฿3,551
฿4,145 total
22 Nov - 23 Nov
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the pool ...
Hyatt Regency St. Louis at The Arch
315 Chestnut St St. Louis MO
The price is ฿4,226 per night from 25 Nov to 26 Nov
฿4,226
฿4,983 total
25 Nov - 26 Nov
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, 3 restaurants and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (4,389 reviews)
"It was a lovely room, great location and I have no complaints. I would stay there again."
Reviewed on 1 Nov 2026
Pear Tree Inn St. Louis Near Union Station
2211 Market Street St. Louis MO
The price is ฿3,513 per night from 15 Nov to 16 Nov
฿3,513
฿4,107 total
15 Nov - 16 Nov
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the restaurant in their ...
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
3550 Samuel Sheppard Drive St. Louis MO
The price is ฿3,491 per night from 22 Nov to 23 Nov
฿3,491
฿4,116 total
22 Nov - 23 Nov
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, a rooftop terrace and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.8/10 Excellent! (1,172 reviews)
"A neat hotel with fun color rooms. It was nice to stay somewhere different from your basic cookie cutter hotel. However, our room was a little run down. You could see some decent wear and tear. The vanity sink drain emitted a bad smell when you ran the water. Seems like the drains need to be cleaned. ..."
Reviewed on 1 Nov 2026
21C Museum Hotel St Louis
1528 Locust street St. Louis MO
The price is ฿4,852 per night from 22 Nov to 23 Nov
฿4,852
฿5,843 total
22 Nov - 23 Nov
includes taxes & fees
Stay at this luxury hotel in St. Louis. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the pool and the restaurant in their reviews. ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Uptown
Find the best Uptown areas for the activities you enjoy most.
Eastport
While visiting Eastport, you might make a stop by sights like Splash City Family Waterpark and Gateway Conference Center.
Mulberry Hills
Though Mulberry Hills may not have many top sights, you can venture to the surrounding area to see attractions like World's Largest Catsup Bottle and Kruta Bakery.
Historic Downtown Collinsville
Though Historic Downtown Collinsville may not have many top sights, you can venture to the surrounding area to see attractions like World's Largest Catsup Bottle and Kruta Bakery.
