Uptown Travel Guide
Collinsville
Stay near popular Uptown attractions
Things to do
St. Louis & Gateway Arch NP Self Guided Walk & Drive Audio Tour
฿557
per traveller
St. Louis Ghost Tour: Sinister Sins & Shadows
฿787
per adult
100% of travellers recommend
Gateway Arch National Park Self Guided Audio Walking Tour
฿492
per traveller
St. Louis: Museum of Illusions Entry Ticket
฿1,148
per adult
90% of travellers recommend
Top hotels in Uptown
Hyatt Regency St. Louis at The Arch
315 Chestnut St St. Louis MO
The price is ฿5,007 per night from 4 Oct to 5 Oct
฿5,007
฿5,904 total
4 Oct - 5 Oct
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, 3 restaurants and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms ...
Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue St. Louis MO
The price is ฿3,440 per night from 4 Oct to 5 Oct
฿3,440
฿4,016 total
4 Oct - 5 Oct
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the pool ...
8.8/10 Excellent! (3,388 reviews)
"Rooms were clean, breakfast was good and staff was incredibly helpful"
Reviewed on 7 Sept 2026
Drury Plaza Hotel St. Louis at the Arch
2 South 4th Street St. Louis MO
The price is ฿4,444 per night from 4 Oct to 5 Oct
฿4,444
฿5,196 total
4 Oct - 5 Oct
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and 2 hot tubs. Our guests praise the breakfast and the pool in their reviews. ...
9.6/10 Exceptional! (3,741 reviews)
"Excellent stay"
Reviewed on 7 Sept 2026
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
3550 Samuel Sheppard Drive St. Louis MO
The price is ฿4,158 per night from 2 Oct to 3 Oct
฿4,158
฿4,903 total
2 Oct - 3 Oct
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, a rooftop terrace and breakfast (surcharge). Our guests praise the helpful staff and the ...
Hampton Inn St. Louis-Downtown (At the Gateway Arch)
333 Washington Ave St. Louis MO
The price is ฿4,022 per night from 13 Sept to 14 Sept
฿4,022
฿4,703 total
13 Sept - 14 Sept
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,394 reviews)
"The guest before me got a tobacco smell in the carpet. The hotel cleaned it but couldn't get the smell out. They sprayed febreeze in the carpet and refunded me the full amount of the room. They even gave us some snacks and drinks for free."
Reviewed on 7 Sept 2026
21C Museum Hotel St Louis
1528 Locust street St. Louis MO
The price is ฿4,729 per night from 27 Sept to 28 Sept
฿4,729
฿5,694 total
27 Sept - 28 Sept
includes taxes & fees
Stay at this luxury hotel in St. Louis. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the pool and the restaurant in their reviews. ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Uptown
Find the best Uptown areas for the activities you enjoy most.
Eastport
While visiting Eastport, you might make a stop by sights like Gateway Conference Center and Splash City Family Waterpark.
Mulberry Hills
Though Mulberry Hills may not have many top sights, you can venture to the surrounding area to see attractions like Gateway Conference Center and FanDuel Sportsbook and Horse Racing.
Historic Downtown Collinsville
Though Historic Downtown Collinsville may not have many top sights, you can venture to the surrounding area to see attractions like Gateway Conference Center and Splash City Family Waterpark.
