Clayton Travel Guide
St. Louis
Popular places to visit
Washington University in St. Louis
Explore the campus of Washington University in St. Louis during your stay in St. Louis. Amble around the area's lush forest or attend a sporting event.
St. Louis Union Station
You can learn more about the history of St. Louis during your trip to a well-known site such as St. Louis Union Station. Experience the area's great live music or attend a baseball game.
Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's fascinating museums or attend a baseball game.
Gateway Arch
Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.
Enterprise Center
Catch an event at Enterprise Center during your trip to St. Louis. Experience the area's fascinating museums or attend a baseball game.
St. Louis Zoo
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
Things to do
St. Louis Ghost Tour: Sinister Sins & Shadows
St. Louis: Museum of Illusions Entry Ticket
St. Louis Premium Small Group Tour With Arch & River Cruise
Downtown St. Louis Smartphone Guided Audio Walking Tour App
St. Louis Premium Driving Tour with Boat Ride & Arch
Gateway Arch National Park Self Guided Audio Walking Tour
Top hotels in Clayton
Clayton Plaza Hotel & Extended Stay
Convenient, friendly staff, great breakfast
Reviewed on 14 Feb 2026
The Ritz-Carlton, St. Louis
Excellent hotel with various restaurants and expansive lobby area.. staff very attentive.
Reviewed on 6 Feb 2026
Le Méridien St. Louis Clayton
Room was beautiful and clean.
Reviewed on 2 Feb 2026
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
Nice staff!
Reviewed on 14 Feb 2026
AC Hotel St. Louis Clayton
My room was spotless and very well put together.
Reviewed on 9 Jan 2026
21C Museum Hotel St Louis
We loved this hotel. It is something you expect in much more sophisticated cities but not St. Louis. Our king bed suite was tastefully furnished and very large. Lots of great touches and very clean. The lobby and museum were stylish and exciting. We ate at both Idolwolf and the cafe. Again great ...
Reviewed on 8 Feb 2026
Other neighbourhoods around Clayton
University City
Noted for its shopping and restaurants, there's plenty to explore in University City. Top attractions like Museum of Transportation and Center of Creative Arts are major draws, and you can hop on the metro at Forsyth Station or U City Big Bend Station to see more of the city.
Dogtown
When in Dogtown, you can plan a visit to St. Louis Zoo and St. Louis Art Museum, some noteworthy sights in the nearby area.
Ladue
Ladue is well liked for its restaurants and churches. If you're hoping to see more of the larger area, Saint Louis Galleria Mall and St. Louis Art Museum are some interesting sights nearby to check out.
The Hill
While The Hill isn't home to many top sights, St. Louis Science Center and Missouri Botanical Gardens and Arboretum are some notable places to visit nearby.
Southwest Garden
While Southwest Garden may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Missouri Botanical Gardens and Arboretum and St. Louis Science Center.
Central West End
If you're looking for things to see and do in Central West End, ample dining options and lush forests are highlights. You might also check out World Chess Hall of Fame while you're visiting, and jump aboard the metro at Central West End Station to get around town.
