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Our top choices for Clayton hotels

Residence Inn By Marriott St. Louis Clayton
Residence Inn By Marriott St. Louis Clayton
Le Méridien St. Louis Clayton
Le Méridien St. Louis Clayton
The Ritz-Carlton, St. Louis
The Ritz-Carlton, St. Louis
AC Hotel St. Louis Clayton
AC Hotel St. Louis Clayton
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
Seven Gables, St. Louis West, a Tribute Portfolio Hotel
Seven Gables, St. Louis West, a Tribute Portfolio Hotel
Clayton Plaza Hotel & Extended Stay
Clayton Plaza Hotel & Extended Stay
Homewood Suites by Hilton St Louis - Galleria
Homewood Suites by Hilton St Louis - Galleria
Tru by Hilton St. Charles St. Louis, MO
Tru by Hilton St. Charles St. Louis, MO
Courtyard by Marriott St Louis Creve Coeur
Courtyard by Marriott St Louis Creve Coeur
Best Western Plus The Charles Hotel
Best Western Plus The Charles Hotel
Comfort Suites St Charles - St Louis
Comfort Suites St Charles - St Louis
Country Inn & Suites by Radisson, St. Peters, MO
Country Inn & Suites by Radisson, St. Peters, MO
Ameristar Casino Resort and Spa
Ameristar Casino Resort and Spa
Drury Plaza Hotel St. Louis St. Charles
Drury Plaza Hotel St. Louis St. Charles
Hampton Inn St. Charles St. Peters
Hampton Inn St. Charles St. Peters
River City Casino & Hotel
River City Casino & Hotel
Embassy Suites by Hilton St. Louis St. Charles
Embassy Suites by Hilton St. Louis St. Charles
Home2 Suites by Hilton St. Louis Downtown
Home2 Suites by Hilton St. Louis Downtown
AC Hotel St. Louis Central West End
AC Hotel St. Louis Central West EndWhere to stay in Clayton

Downtown St. Louis
Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Busch Stadium – discover Downtown St. Louis, a destination also famous for its historic sites.
Berkeley
Visitors highly recommend Berkeley for its abundant dining options, and you can make a stop by James S. McDonnell Prologue Room while you're in town.

Central West End
Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

Downtown West
While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and St. Louis Aquarium at Union Station.

Soulard
You'll enjoy the bars and churches in Soulard. You might want to make time for a stop at Anheuser-Busch Brewery or Soulard Farmer's Market.
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