A grand church interior with high vaulted ceilings, large columns, and a central altar.

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Our top choices for Santo Spirito hotels with a spa

Agriturismo Fattoria Lavacchio

Agriturismo Fattoria Lavacchio
Pontassieve
9.6 out of 10, Exceptional, (84 reviews)
  • cleanliness
    Tuscan farm stay offers vineyard views, spa indulgences, and a seasonal outdoor pool for an enchanting escape in the countryside.
The price is ฿8,774
฿9,727 total
includes taxes & fees
24 Jul - 25 Jul
Agriturismo Fattoria Lavacchio

Viesca Toscana Suites & Villas

Viesca Toscana Suites & Villas
Reggello
9.4 out of 10, Exceptional, (8 reviews)
  • cleanliness
    Serene spa retreat in the Tuscan countryside offers deep-tissue and hot stone massages in three tranquil treatment rooms.
The price is ฿13,437
฿14,857 total
includes taxes & fees
30 Jul - 31 Jul
Viesca Toscana Suites & Villas

Villa Casagrande Resort & SPA

Villa Casagrande Resort & SPA
4.0 star property
Figline e Incisa Valdarno
9.2 out of 10, Wonderful, (398 reviews)
  • cleanliness
    Rejuvenate at this Tuscan retreat where couples spa treatments, winery experiences, and poolside relaxation create a tranquil escape.
The price is ฿5,402
฿6,094 total
includes taxes & fees
2 Aug - 3 Aug
Villa Casagrande Resort & SPA

Country Hotel Borgo Sant'Ippolito

Country Hotel Borgo Sant'Ippolito
4.0 star property
Lastra a Signa
9.0 out of 10, Wonderful, (260 reviews)
  • cleanliness
    Escape to a Tuscan countryside retreat where luxurious spa treatments and garden views create a peaceful sanctuary.
The price is ฿4,355
฿4,981 total
includes taxes & fees
12 Jul - 13 Jul
Country Hotel Borgo Sant'Ippolito

Villa Tolomei Hotel & Resort

Villa Tolomei Hotel & Resort
5.0 star property
Oltrarno
8.8 out of 10, Excellent, (417 reviews)
  • cleanliness
    Experience deep relaxation at this luxury Florence hotel with a hammam, seasonal outdoor pool, and rejuvenating in-room massage services.
The price is ฿6,599
฿7,867 total
includes taxes & fees
30 Jul - 31 Jul
Villa Tolomei Hotel & Resort

Incanto Relais & Charme

Incanto Relais & Charme
Careggi Rifredi
9.2 out of 10, Wonderful, (5 reviews)
The price is ฿3,979
฿4,833 total
includes taxes & fees
1 Aug - 2 Aug
Incanto Relais & Charme

Tenuta Moriano

Tenuta Moriano
Montespertoli
10.0 out of 10, Exceptional, (6 reviews)
  • cleanliness
    Tuscan farmhouse spa with seasonal pools and winery tours provides deep massage treatments in serene garden setting.
The price is ฿4,327
฿7,386 total
includes taxes & fees
9 Jul - 10 Jul
Tenuta Moriano

Pieve Aldina - Relais & Châteaux

Pieve Aldina - Relais & Châteaux
5.0 star property
Radda in Chianti
10.0 out of 10, Exceptional, (40 reviews)
  • cleanliness
    Soothing spa escape at this country hotel with indulgent body treatments, a steam room, and a peaceful garden setting.
The price is ฿12,216
฿13,742 total
includes taxes & fees
2 Aug - 3 Aug
Pieve Aldina - Relais & Châteaux

Villa il Poggiale - Dimora Storica

Villa il Poggiale - Dimora Storica
San Casciano in Val di Pesa
9.6 out of 10, Exceptional, (150 reviews)
  • cleanliness
    Relax in a historic Tuscan villa with couples spa treatments, Turkish bath, and tranquil garden setting for the ultimate wellness retreat.
The price is ฿5,350
฿5,923 total
includes taxes & fees
10 Jul - 11 Jul
Villa il Poggiale - Dimora Storica

COMO Castello Del Nero

COMO Castello Del Nero
5.0 star property
Barberino Tavarnelle
9.6 out of 10, Exceptional, (141 reviews)
  • cleanliness
    Surrender to blissful wellness in a Tuscan retreat where hot stone massages and aromatherapy treatments await in couples' spa rooms.
The price is ฿27,346
฿30,385 total
includes taxes & fees
1 Aug - 2 Aug
COMO Castello Del Nero
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Choose what matters most at spa hotels in Santo Spirito

Top Santo Spirito Hotel Reviews

Frequently asked questions

Looking to holiday at a spa hotel in Santo Spirito?
Treat yourself to some time in a luxurious spa hotel and you won't regret it. Travellers like the riverfront in Santo Spirito. Take in the culture at the art galleries and monuments during your stay. Spa hotels are a great way to break away from your daily routine and add a layer of luxury to your stay.
What is the best spa hotel in Santo Spirito?
Della Calza Spa & Foresteria is a top spa hotel featuring a bar, an indoor pool and a restaurant. Spend an afternoon at the spa where you'll find facials, body treatments and couples treatments.
How many spa hotels are there in Santo Spirito?
Among Expedia's 474 accommodation options in Santo Spirito, there is 1 spa hotel.
What's there to see and do in Santo Spirito?
Experience all that Santo Spirito has to offer when you visit Piazza Santo Spirito, Santo Spirito Basilica and Arno River. If you have extra time while you're in the area, you might want to see Piazza del Carmine and Santa Maria della Carmine.
What is a Santo Spirito spa hotel?
Spa hotels in Santo Spirito have full on-site spas and offer services including facials and a selection of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are great for rest, rejuvenation and relaxation.