Search Holiday Rentals in Santa Cruz

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Check prices for these dates

Tonight
9 Dec - 10 Dec
Tomorrow
10 Dec - 11 Dec
This weekend
12 Dec - 14 Dec
Next weekend
19 Dec - 21 Dec

Our top choices for Santa Cruz holiday rentals

Classic Loft | Private kitchen | Full-sized fridge, microwave, cookware/dishes/utensils
Lofts by Verticca

Lofts by Verticca

3.5 star property
Ojo de Agua
8.2 out of 10, Very good, (12)
"This was absolutely wonderful they were kind and friendly the loft was very clean and spacious only thing I didn’t like was the tv’s weren’t smart tv’s they only had local cable channels "
United States
Berline
The price is ฿2,226
฿2,672 total
includes taxes & fees
10 Dec - 11 Dec
Lofts by Verticca
Standard Double Suite | City view
UTOPIC Polanco by ULIV

UTOPIC Polanco by ULIV

4.5 star property
Miguel Hidalgo
9.0 out of 10, Wonderful, (724)
"We had a great stay. Area was safe to walk around, and hotel was near tourist attractions. "
United States
Guadalupe
UTOPIC Polanco by ULIV
Exterior
Casa Chopo

Casa Chopo

3.5 star property
Downtown Mexico City
9.4 out of 10, Exceptional, (100)
"Gorgeous property. "
United States
Jeff
The price is ฿1,364
฿1,651 total
includes taxes & fees
12 Dec - 13 Dec
Casa Chopo
Terrace/patio
The Wild Oscar

The Wild Oscar

4.0 star property
Polanco
9.6 out of 10, Exceptional, (483)
"Don't delay - book the Wild Óscar "
United States
Kasha
The Wild Oscar
Terrace/patio
Las Suites Campos Eliseos

Las Suites Campos Eliseos

4.0 star property
Polanco
9.2 out of 10, Wonderful, (1345)
"The staff was top notch"
United States
Alan
The price is ฿5,155
฿6,161 total
includes taxes & fees
5 Jan - 6 Jan 2026
Las Suites Campos Eliseos
Indoor spa tub
UTOPIC Platón by ULIV

UTOPIC Platón by ULIV

5.0 star property
Polanco
9.4 out of 10, Exceptional, (123)
"Very clean and safe place."
United States
NIDIA DENICE
The price is ฿4,082
฿4,878 total
includes taxes & fees
15 Dec - 16 Dec
UTOPIC Platón by ULIV
Junior Apartment | Living area | Flat-screen TV
Bright & sweet unit in middle Polanco

Bright & sweet unit in middle Polanco

3.0 star property
Polanco
9.8 out of 10, Exceptional, (43)
"Very cozy and clean. Good walking distance from all types of restaurants."
United States
Lissette
The price is ฿1,610
฿2,746 total
includes taxes & fees
15 Dec - 16 Dec
Bright & sweet unit in middle Polanco
Exterior
ULIV Polanco

ULIV Polanco

3.5 star property
Polanco
8.6 out of 10, Excellent, (106)
"Clean aparrnent. Very polite and helpful staff, especially Teresa"
United States
Galia
ULIV Polanco
Rooftop terrace
ULIV Apartments Polanco

ULIV Apartments Polanco

4.0 star property
Miguel Hidalgo
8.8 out of 10, Excellent, (299)
"Clean and friendly staff"
United States
Claudia
ULIV Apartments Polanco
Rooftop terrace
Capitalia Aristoteles Polanco

Capitalia Aristoteles Polanco

4.0 star property
Polanco
9.2 out of 10, Wonderful, (110)
"Great location and a nice apartment "
United States
Luis F
The price is ฿4,882
฿5,907 total
includes taxes & fees
6 Jan - 7 Jan 2026
Capitalia Aristoteles Polanco
Two-Bedroom Apartment with Huge Private Patio | Terrace/patio
ULIV Parque Lincoln

ULIV Parque Lincoln

3.5 star property
Polanco
9.6 out of 10, Exceptional, (816)
"Staff was great , same as location!"
United States
Ilan
ULIV Parque Lincoln
Hypo-allergenic bedding, in-room safe, individually decorated
Kukun Inspire Polanco

Kukun Inspire Polanco

4.0 star property
Polanco
9.4 out of 10, Exceptional, (206)
"Loved the view from the balcony and very friendly staff. "
United States
Claudia
The price is ฿3,545
฿4,289 total
includes taxes & fees
6 Jan - 7 Jan 2026
Kukun Inspire Polanco
Front of property
Residence L'heritage Aristóteles 225 by Bluebay

Residence L'heritage Aristóteles 225 by Bluebay

3.0 star property
Polanco
7.2 out of 10, Good, (377)
"Excelente servico"
Mexico
José
The price is ฿2,689
฿3,253 total
includes taxes & fees
2 Jan - 3 Jan 2026
Residence L'heritage Aristóteles 225 by Bluebay
City view
Casa Sócrates by Kukun

Casa Sócrates by Kukun

2.0 star property
Polanco
8.6 out of 10, Excellent, (146)
"The noise in the first floor rooms is terrible. You won’t be able to sleep. "
United States
Daniel
Casa Sócrates by Kukun
Apartment, 1 Bedroom | Living area | LCD TV
Nido Parque Lincoln

Nido Parque Lincoln

3.0 star property
Polanco
9.0 out of 10, Wonderful, (197)
"Very nice place to stay "
United States
Virginia
Nido Parque Lincoln
Interior detail
Residence L'heritage Aristóteles 140 by Bluebay

Residence L'heritage Aristóteles 140 by Bluebay

3.5 star property
Polanco
7.4 out of 10, Good, (419)
"Excelente todo "
Mexico
Edith
The price is ฿1,769
฿2,140 total
includes taxes & fees
1 Jan - 2 Jan 2026
Residence L'heritage Aristóteles 140 by Bluebay
Jr. Penthouse with a Private Terrace | Living area | 50-inch Smart TV with digital channels, Netflix, streaming services
ULIV Park Polanco

ULIV Park Polanco

3.0 star property
Polanco
9.4 out of 10, Exceptional, (86)
"It was a great stay in the perfect location. The space was incredibly clean and the staff were always so helpful and kind! "
United States
Brenda
ULIV Park Polanco
Exterior
ULIV Family Apartments Polanco

ULIV Family Apartments Polanco

4.0 star property
Miguel Hidalgo
9.4 out of 10, Exceptional, (27)
"Excellent location and very secure to walk around. "
United States
Carlos
ULIV Family Apartments Polanco
In-room safe, blackout curtains, free WiFi, bed sheets
Hotel Monaco

Hotel Monaco

3.5 star property
Historic Center
8.0 out of 10, Very good, (806)
"The staff was exceptionally helpful and kind. I don't think I've ever felt so welcome at a hotel! Our dog was also welcome, which was a relief. "
United States
Chris
The price is ฿1,661
฿1,985 total
includes taxes & fees
10 Dec - 11 Dec
Hotel Monaco
Luxury Apartment, Balcony, City View | Dining room
Capitalia Antara Polanco

Capitalia Antara Polanco

4.5 star property
Polanco
9.2 out of 10, Wonderful, (169)
"Super smooth. Great rooms!!"
United States
Javier
Capitalia Antara Polanco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

Capitalia Antara Polanco

Capitalia Antara Polanco

10/10 Excellent
"El senor del front desk es super amable nos sentimos en casa ... felicitacipnes"
Liliana 1-night trip
Posted 9 hours ago
Capitalia Antara Polanco

Find out more about Santa Cruz

Search for holiday rentals in Santa Cruz on Expedia! You can easily find your home rentals, villas, holiday apartments in Santa Cruz using one of the methods below:

  • View our selection of featured holiday rentals in Santa Cruz
  • Use the map to find apartments and other holiday homes in the Santa Cruz neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Santa Cruz while they last

Look no further and take a look at our great range of rental properties in Santa Cruz!

Frequently asked questions

Are there holiday rentals in Santa Cruz?

Yes, there are holiday rentals close to the most popular sights in Santa Cruz, or you can select a more secluded option if you're looking for a relaxing stay.

What’s there to see and do in Santa Cruz?

Explore the area and family-friendly sights such as Planetario Luis Enrique Erro, or get out into nature at a spot like Hacienda La Concepcion. Temple of San Francisco Javier and National Museum of the Viceroyalty are a couple of places you'll find in the wider area.

What’s a holiday rental in Santa Cruz like?

Holiday rentals are private properties where you can stay for a few weeks, or just a few days, in Santa Cruz. Holiday rentals offer amenities such as laundry facilities and kitchens so you'll feel just like you're staying in your own home. If you're concerned about a sanitised environment, holiday rentals can provide a sense of privacy away from public hotel lifts and lobbies packed with people while still allowing you a great travel experience. You'll also have more space in a holiday rental than in a hotel, which is another reason why a holiday rental is a great choice for a family getaway.