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13 Oct - 14 Oct
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Top Trending Hotels Near San Francisco, Panama City

Courtyard by Marriott Panama Multiplaza Mall
Daily cooked-to-order breakfast (USD 15.00 per person)
Courtyard by Marriott Panama Multiplaza Mall
4.0 star property
8.8 out of 10, Excellent, (1006)
"Perfect stay "
The price is ฿4,237
฿4,661 total
includes taxes & fees
1 Nov - 2 Nov
Courtyard by Marriott Panama Multiplaza Mall
Aloft Panama
Exterior
Aloft Panama
3.5 star property
8.6 out of 10, Excellent, (864)
"We stayed here for a week and it was filled with happy staff who were very courteous ! They made sure we were taken care of at all times and I will stay here again when we return. "
The price is ฿3,612
฿3,974 total
includes taxes & fees
1 Nov - 2 Nov
Aloft Panama
Sheraton Grand Panama
Terrace/patio
Sheraton Grand Panama
4.0 star property
8.6 out of 10, Excellent, (964)
"Relaxing but close by to everything "
The price is ฿4,140
฿4,554 total
includes taxes & fees
1 Nov - 2 Nov
Sheraton Grand Panama
Boutique Apartments Panamá Coco del Mar
Outdoor pool
Boutique Apartments Panamá Coco del Mar
3.5 star property
7.4 out of 10, Good, (142)
"GORGEOUS view!!! And very spacious "
The price is ฿1,254
฿5,803 total
includes taxes & fees
14 Oct - 15 Oct
Boutique Apartments Panamá Coco del Mar
Megapolis Hotel Panamá
Front of property
Megapolis Hotel Panamá
4.5 star property
8.4 out of 10, Very good, (1123)
"Great place "
The price is ฿4,088
฿4,497 total
includes taxes & fees
26 Oct - 27 Oct
Megapolis Hotel Panamá
Plaza Paitilla Inn Hotel
View from property
Plaza Paitilla Inn Hotel
3.5 star property
9.4 out of 10, Exceptional, (2122)
"Stayed 4 nights excellent property and views from the room"
The price is ฿4,937
฿5,430 total
includes taxes & fees
14 Oct - 15 Oct
Plaza Paitilla Inn Hotel
JW Marriott Panama
4 outdoor pools, free pool cabanas, pool umbrellas
JW Marriott Panama
5.0 star property
8.8 out of 10, Excellent, (1013)
"The staff is top notch, the accommodations amazing, the dining options great, close to airport and activities "
The price is ฿7,753
฿8,528 total
includes taxes & fees
1 Nov - 2 Nov
JW Marriott Panama
Decapolis Hotel Panama City
Exterior
Decapolis Hotel Panama City
4.0 star property
8.6 out of 10, Excellent, (1351)
"Good price , location and tasty breakfast "
The price is ฿2,773
฿3,050 total
includes taxes & fees
17 Oct - 18 Oct
Decapolis Hotel Panama City
San Francisco by Wynwood House
Lobby sitting area
San Francisco by Wynwood House
3.0 star property
9.2 out of 10, Wonderful, (50)
"Good comfy rooms"
The price is ฿3,280
฿4,425 total
includes taxes & fees
14 Oct - 15 Oct
San Francisco by Wynwood House
Las Americas Golden Tower Panama
View from property
Las Americas Golden Tower Panama
4.0 star property
9.0 out of 10, Wonderful, (1009)
"We ejoyed our stay here, very nice pool and gym area."
The price is ฿4,353
฿4,788 total
includes taxes & fees
31 Oct - 1 Nov
Las Americas Golden Tower Panama
Residence Inn by Marriott Panama City
Outdoor pool, open 6:00 AM to 11:00 PM, pool umbrellas, pool loungers
Residence Inn by Marriott Panama City
4.0 star property
9.0 out of 10, Wonderful, (516)
"Stayed here while a relative was hospitalized, easy access to the hospital and shopping center with lots of food options. If visiting Panama city it is very conveniently located."
The price is ฿4,418
฿4,860 total
includes taxes & fees
7 Nov - 8 Nov
Residence Inn by Marriott Panama City
Boutique Apartments Atlapa
Outdoor pool
Boutique Apartments Atlapa
3.0 star property
7.4 out of 10, Good, (21)
"I had an excellent stay here ! It was a very amazing the host is an amazing person thank you for making My stay great❤️"
Boutique Apartments Atlapa
Casa Orquídea
Terrace/patio
Casa Orquídea
2.0 star property
9.0 out of 10, Wonderful, (2)
"For me was very convenient "
The price is ฿2,501
฿2,751 total
includes taxes & fees
25 Oct - 26 Oct
Casa Orquídea
Wanders Panama by Boutique Apartments
Outdoor pool
Wanders Panama by Boutique Apartments
4.0 star property
10.0 out of 10, Exceptional, (1)
"I will go again thank you so much"
The price is ฿3,151
฿7,026 total
includes taxes & fees
22 Oct - 23 Oct
Wanders Panama by Boutique Apartments
w Bright 1BR w Private Balcony in San Francisco
Apartment | Internet
w Bright 1BR w Private Balcony in San Francisco
2.0 star property
The price is ฿3,210
฿4,502 total
includes taxes & fees
26 Oct - 27 Oct
w Bright 1BR w Private Balcony in San Francisco
w Premium 1BR w Balcony in San Francisco
Apartment | 1 bedroom, Internet
w Premium 1BR w Balcony in San Francisco
2.0 star property
The price is ฿3,288
฿4,588 total
includes taxes & fees
21 Oct - 22 Oct
w Premium 1BR w Balcony in San Francisco
Crowne Plaza Panama Airport by IHG
Outdoor pool, pool umbrellas, pool loungers
Crowne Plaza Panama Airport by IHG
4.0 star property
8.4 out of 10, Very good, (2242)
"Great location "
The price is ฿3,505
฿3,855 total
includes taxes & fees
1 Nov - 2 Nov
Crowne Plaza Panama Airport by IHG
Central Hotel Panama Casco Viejo
47-inch flat-screen TV with cable channels, TV
Central Hotel Panama Casco Viejo
4.0 star property
9.0 out of 10, Wonderful, (1004)
"Very beautiful hotel with helpful staff. Very good dining options. "
Central Hotel Panama Casco Viejo
Hotel Riu Plaza Panama
Outdoor pool, pool loungers
Hotel Riu Plaza Panama
5.0 star property
9.0 out of 10, Wonderful, (4386)
"Great buffet, nice pool."
The price is ฿3,879
฿4,267 total
includes taxes & fees
5 Nov - 6 Nov
Hotel Riu Plaza Panama
Arcadia Condo Suites
50-inch LED TV with satellite channels
Arcadia Condo Suites
2.5 star property
9.4 out of 10, Exceptional, (99)
"Wonderful place great staff "
The price is ฿1,824
฿3,517 total
includes taxes & fees
14 Oct - 15 Oct
Arcadia Condo Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in San Francisco

Find the best San Francisco areas for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Interoceanic Canal Museum or National Theater while you're exploring the area.

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip.

Punta Paitilla

Punta Paitilla is known for its abundant dining options, and you can plan a trip to Avenida Balboa and Multicentro Panama while you're in town.

Calidonia

Calidonia is a destination travellers like for its shopping, and you might hop aboard the metro at Estación Lotería or Santo Tomas Station to explore sights like Cinta Costera.

Top San Francisco Hotel Reviews

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

10/10 Excellent
"Friendly staff all around"
WYCLIFFE 4-night trip
Posted 22 hours ago
Hotel Riu Plaza Panama

Explore a world of travel with Expedia

Frequently asked questions

What is San Francisco like?
San Francisco is a welcoming neighbourhood that travellers like for its restaurants. Make sure that you visit Multiplaza Pacific Mall and Calle 50 as part of your San Francisco travel plans.
Where is the best hotel for a stay in San Francisco?
Based on Expedia customer reviews, Ramada Plaza by Wyndham Panama Punta Pacifica is the highest ranked property in San Francisco. This hotel is a short 4-minute walk from Multiplaza Pacific Mall, and it offers free breakfast and a restaurant. Other top choices in the neighbourhood include Plaza Paitilla Inn Hotel and Residence Inn by Marriott Panama City.
How many hotels can I expect to find in San Francisco?
If you're searching for places to stay in Panama City, Expedia has something to meet your needs with 213 San Francisco hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in San Francisco, will I receive a refund?
Yes! Most hotel reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of booking. Add dates, click "Search", then use the filter option "fully refundable" to view the best deals in San Francisco.
What is there to do in this Panama City neighbourhood?
While you're in San Francisco, a shopping trip to Multiplaza Pacific Mall, Avenida Balboa or Pacific Center might be the perfect way to find that souvenir you've been looking for. Calle 50 and Panama Canal Murals are some other stops worth a visit in the neighbourhood. A few places to visit in the area around San Francisco include Colonial Religious Art Museum, Bingo 90 and Soho City Center. When you're sightseeing in Panama City, National Shrine of the Heart of Mary and Panama Viejo Museum are also worth a stop.