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Our top choices for San Francisco hotels

JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,005 reviews)
"The staff was very friendly and the whole property made you feel Safe!"
United States
Michael
The price is ฿8,035
฿8,839 total
includes taxes & fees
21 Feb - 22 Feb
JW Marriott Panama

Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,000 reviews)
"Super friendly staff"
United States
Geoffrey
The price is ฿4,160
฿4,577 total
includes taxes & fees
20 Feb - 21 Feb
Sheraton Grand Panama

Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall
4.0 star property
San Francisco
8.8 out of 10, Excellent, (1,000 reviews)
"Clean room, friendly staff, very good breakfast and more. "
United States
Patricia
The price is ฿2,874
฿3,162 total
includes taxes & fees
20 Feb - 21 Feb
Courtyard by Marriott Panama Multiplaza Mall

Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
San Francisco
9.6 out of 10, Exceptional, (1,147 reviews)
"Great staff, breakfast and location "
Canada
Corinne
The price is ฿3,453
฿3,799 total
includes taxes & fees
2 Feb - 3 Feb
Ramada Plaza by Wyndham Panama Punta Pacifica

Aloft Panama

Aloft Panama
3.5 star property
San Francisco
8.6 out of 10, Excellent, (923 reviews)
"Perfect stay for a few days at Panama!"
United States
Maria
The price is ฿3,686
฿4,054 total
includes taxes & fees
1 Feb - 2 Feb
Aloft Panama

Residence Inn by Marriott Panama City

Residence Inn by Marriott Panama City
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (559 reviews)
"Great location, friendly staff, clean rooms, very comfortable beds. "
United States
Sharna
The price is ฿4,984
฿5,483 total
includes taxes & fees
20 Feb - 21 Feb
Residence Inn by Marriott Panama City

Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,005 reviews)
"Great staff, great room, great time in Panama"
United States
Darius
The price is ฿4,741
฿5,215 total
includes taxes & fees
9 Feb - 10 Feb
Las Americas Golden Tower Panama

Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
San Francisco
8.4 out of 10, Very good, (1,379 reviews)
"Clean room,helpful staff around the hotel,good food options"
United States
Umar
Megapolis Hotel Panamá

Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
San Francisco
9.4 out of 10, Exceptional, (2,157 reviews)
"Definitely a great place to stay. Staff was excellent. "
United States
Eric
The price is ฿3,349
฿3,684 total
includes taxes & fees
3 Feb - 4 Feb
Plaza Paitilla Inn Hotel

Boutique Apartments Panamá Coco del Mar

Boutique Apartments Panamá Coco del Mar
3.5 star property
San Francisco
7.4 out of 10, Good, (165 reviews)
"Love it!! Very nice!! "
United States
TEYLING
The price is ฿1,875
฿6,444 total
includes taxes & fees
1 Feb - 2 Feb
Boutique Apartments Panamá Coco del Mar

Decapolis Hotel Panama City

Decapolis Hotel Panama City
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,512 reviews)
"Nice comfortable hotel and very friendly staff."
Canada
norah
Decapolis Hotel Panama City

Boutique Apartments Atlapa

Boutique Apartments Atlapa
3.0 star property
San Francisco
7.8 out of 10, Good, (29 reviews)
"I had an excellent stay here ! It was a very amazing the host is an amazing person thank you for making My stay great❤️"
United States
Shamia
Boutique Apartments Atlapa

Wanders Panama by Boutique Apartments

Wanders Panama by Boutique Apartments
4.0 star property
San Francisco
10.0 out of 10, Exceptional, (2 reviews)
"The apartment was great. It was very comfortable and spacious. The building is impressive and a great place from which to enjoy Panama City. "
United States
Gary
The price is ฿4,840
฿10,103 total
includes taxes & fees
1 Feb - 2 Feb
Wanders Panama by Boutique Apartments

Casa Orquídea

Casa Orquídea
2.0 star property
San Francisco
8.0 out of 10, Very good, (5 reviews)
"For me was very convenient "
United States
Natalia
The price is ฿1,833
฿2,016 total
includes taxes & fees
18 Feb - 19 Feb
Casa Orquídea

Dovle Residences by HMS-Preferred Member

Dovle Residences by HMS-Preferred Member
3.0 star property
San Francisco
2.8 out of 10, (3 reviews)
"Inadequate heating in the pool , poor customer service. No hot water in the shower. It was a terrible experience but it’s a nice place, hopefully with better management can offer outstanding services "
United States
Herbert
The price is ฿5,977
฿6,575 total
includes taxes & fees
31 Jan - 1 Feb
Dovle Residences by HMS-Preferred Member

Living 73 Panamá by Boutique Apartments

Living 73 Panamá by Boutique Apartments
3.0 star property
San Francisco
The price is ฿1,666
฿6,462 total
includes taxes & fees
1 Feb - 2 Feb
Living 73 Panamá by Boutique Apartments

w Engaging 1BR w Balcony in San Francisco

w Engaging 1BR w Balcony in San Francisco
2.0 star property
San Francisco
The price is ฿3,792
฿5,151 total
includes taxes & fees
1 Feb - 2 Feb
w Engaging 1BR w Balcony in San Francisco

Dovle 506 in Ciudad de Panam

Dovle 506 in Ciudad de Panam
2.0 star property
San Francisco
The price is ฿7,843
฿9,700 total
includes taxes & fees
18 Feb - 19 Feb
Dovle 506 in Ciudad de Panam

Relaxing 2BR Apt at Coco del mar

Relaxing 2BR Apt at Coco del mar
2.0 star property
San Francisco
The price is ฿7,843
฿8,627 total
includes taxes & fees
28 Jan - 29 Jan
Relaxing 2BR Apt at Coco del mar

Two-level Apt by Panama old Town

Two-level Apt by Panama old Town
2.0 star property
San Francisco
The price is ฿4,651
฿6,003 total
includes taxes & fees
1 Feb - 2 Feb
Two-level Apt by Panama old Town
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in San Francisco

Find the best San Francisco areas for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Interoceanic Canal Museum or Museum of History Panama while you're exploring the area.

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Crown Casino.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip.

San Felipe

While visiting San Felipe, you might make a stop by sights like Interoceanic Canal Museum and Museum of History Panama.

Punta Paitilla

Punta Paitilla is known for its abundant dining options, and you can plan a trip to Avenida Balboa and Multicentro Panama while you're in town.

Top San Francisco Hotel Reviews

Frequently asked questions

What is San Francisco like?
San Francisco is a welcoming neighbourhood that travellers like for its restaurants. Make sure that you visit Multiplaza Pacific Mall and Calle 50 as part of your San Francisco travel plans.
Where is the best hotel for a stay in San Francisco?
Based on Expedia customer reviews, Ramada Plaza by Wyndham Panama Punta Pacifica is the highest ranked property in San Francisco. This hotel is a short 4-minute walk from Multiplaza Pacific Mall, and it offers free breakfast and a restaurant. Other top choices in the neighbourhood include Plaza Paitilla Inn Hotel and Residence Inn by Marriott Panama City.
How many hotels can I expect to find in San Francisco?
If you're searching for places to stay in Panama City, Expedia has something to meet your needs with 254 San Francisco hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in San Francisco, will I receive a refund?
Yes! Most hotel reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of booking. Add dates, click "Search", then use the filter option "fully refundable" to view the best deals in San Francisco.
What is there to do in this Panama City neighbourhood?
While you're in San Francisco, a shopping trip to Multiplaza Pacific Mall, Avenida Balboa or Pacific Center might be the perfect way to find that souvenir you've been looking for. Calle 50 and Panama Canal Murals are some other stops worth a visit in the neighbourhood. A few places to visit in the area around San Francisco include Colonial Religious Art Museum, Bingo 90 and Soho City Center. When you're sightseeing in Panama City, National Shrine of the Heart of Mary and Panama Viejo Museum are also worth a stop.