Search Luxury Hotels in Mission District

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Mission District Luxury Hotels

Our top choices for Mission District luxury hotels

Sun deck

Casa Madrona Hotel & Spa

Casa Madrona Hotel & Spa
4.0 star property
Downtown
9.2 out of 10, Wonderful, (1,002 reviews)
  • cleanliness
    Sausalito sanctuary delivers champagne service, spa indulgences, and breathtaking bay views in a sophisticated coastal setting.
The price is ฿10,259
฿12,639 total
includes taxes & fees
9 Jul - 10 Jul
Casa Madrona Hotel & Spa
Property entrance

Hotel VIA

Hotel VIA
4.0 star property
Downtown San Francisco
9.2 out of 10, Wonderful, (1,560 reviews)
The price is ฿6,758
฿7,954 total
includes taxes & fees
4 Jul - 5 Jul
Hotel VIA
Exterior

Kimpton Alton Fisherman's Wharf by IHG

Kimpton Alton Fisherman's Wharf by IHG
4.5 star property
Fisherman's Wharf
9.0 out of 10, Wonderful, (1,510 reviews)
  • cleanliness
    Waterfront luxury flourishes at this San Francisco hotel offering spa services and daily receptions near iconic attractions.
The price is ฿5,410
฿7,757 total
includes taxes & fees
5 Jul - 6 Jul
Kimpton Alton Fisherman's Wharf by IHG
Lobby

Omni San Francisco Hotel

Omni San Francisco Hotel
4.5 star property
Downtown San Francisco
9.6 out of 10, Exceptional, (1,267 reviews)
  • cleanliness
    Luxury city centre retreat offers pillowtop beds, upscale dining, and attentive service in San Francisco.
The price is ฿5,738
฿8,105 total
includes taxes & fees
4 Jul - 5 Jul
Omni San Francisco Hotel
Courtyard

DoubleTree by Hilton San Francisco Airport

DoubleTree by Hilton San Francisco Airport
4.0 star property
Bayfront
8.8 out of 10, Excellent, (1,563 reviews)
  • cleanliness
    Luxurious airport retreat offers 24-hour fitness, premium dining, and concierge services.
The price is ฿4,467
฿5,078 total
includes taxes & fees
5 Jul - 6 Jul
DoubleTree by Hilton San Francisco Airport
Restaurant

The Westin St. Francis San Francisco on Union Square

The Westin St. Francis San Francisco on Union Square
4.5 star property
Union Square
8.8 out of 10, Excellent, (2,327 reviews)
  • cleanliness
    Historic luxury in Union Square with fitness centre, fine dining, and concierge services.
The price is ฿6,853
฿9,541 total
includes taxes & fees
20 Jun - 21 Jun
The Westin St. Francis San Francisco on Union Square
Property amenity

Oakland Marriott City Center

Oakland Marriott City Center
4.0 star property
Downtown Oakland
9.0 out of 10, Wonderful, (1,000 reviews)
  • cleanliness
    Luxurious city centre retreat offers city views, designer toiletries, and premium bedding for Oakland indulgence.
The price is ฿4,164
฿4,849 total
includes taxes & fees
3 Jul - 4 Jul
Oakland Marriott City Center
2 restaurants; breakfast, lunch, dinner and brunch served

San Francisco Proper Hotel

San Francisco Proper Hotel
4.5 star property
Downtown San Francisco
8.8 out of 10, Excellent, (864 reviews)
The price is ฿5,403
฿8,093 total
includes taxes & fees
19 Jul - 20 Jul
San Francisco Proper Hotel
Restaurant

Hotel G San Francisco

Hotel G San Francisco
4.0 star property
Union Square
9.2 out of 10, Wonderful, (1,001 reviews)
The price is ฿3,797
฿5,781 total
includes taxes & fees
21 Jun - 22 Jun
Hotel G San Francisco
Exterior

Hotel Adagio, Autograph Collection

Hotel Adagio, Autograph Collection
4.0 star property
Union Square
8.6 out of 10, Excellent, (1,001 reviews)
The price is ฿3,869
฿5,710 total
includes taxes & fees
6 Jul - 7 Jul
Hotel Adagio, Autograph Collection
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Mission District Hotel Reviews

DoubleTree by Hilton Hotel Berkeley Marina

DoubleTree by Hilton Hotel Berkeley Marina

10/10 Excellent
"The front desk was welcoming and helpful. I also like the fact that there several walking trails immediately adjacent to the property."
Brian 1-night trip
Posted less than an hour ago
DoubleTree by Hilton Hotel Berkeley Marina

Frequently asked questions

Are you searching for a great accommodation for your luxury trip to Mission District?
Use Expedia to arrange your flight to San Francisco International Airport (SFO) airport or Oakland, CA (OAK-Oakland Intl.) airport, and then select from a variety of places to stay that will deliver the luxury you want. Amenities are an important consideration when you plan a holiday, so we make it easy to find what you'd like to make your stay relaxing and comfortable. If you want a posh hotel that has a spa, an indoor pool or luxury bedding, Expedia can help you find the best luxury hotel experience that Mission District offers. During your visit, you might want to enjoy the bars which Mission District is known for.
What's there to see and do in Mission District?
Take in the sights and attractions that Mission District offers with a visit to Southern Exposure, San Francisco Public Library and SOMA Pilipinas. If you have spare time during your trip, you might want to make a stop at Incline Gallery and Marsh Theater.
How can I get around Mission District?
It's easier to get around town comfortably when you know your options. Walk to nearby metro stations such as 16th Street Mission Station, 24th Street Mission Station and Right Of Way/20th St Stop.