South Main Travel Guide
Houston
Visit South Main
Things to do
Houston: Space Center Houston Admission Ticket
฿984
per adult
92% of travellers recommend
Houston Museum of Natural Sciences: Planetarium Ticket
฿394
per adult
80% of travellers recommend
Houston's Official City & Mural Tour!
฿2,626
per adult
88% of travellers recommend
Houston: Museum of Natural Science General Admission Ticket
฿821
per adult
98% of travellers recommend
NASA's Space Center & Official Houston City Tour with tickets
฿3,579
per adult
92% of travellers recommend
Houston: Holocaust Museum Houston Entry Ticket
฿723
per adult
90% of travellers recommend
Top hotels in South Main
Wyndham Houston near NRG Park/Medical Center
8686 Kirby Drive Houston TX
The price is ฿3,056 per night from 3 Aug to 4 Aug
฿3,056
฿3,576 total
3 Aug - 4 Aug
includes taxes & fees
Stay at this business-friendly hotel in Houston. Enjoy free Wi-Fi, a 24-hour fitness centre and a 24-hour front desk. Our guests praise the helpful staff and ...
7/10 Good! (1,344 reviews)
"Clean room"
Reviewed on 13 Jul 2026
Grand Tuscany Hotel
12801 Northwest Fwy Houston TX
The price is ฿3,110 per night from 19 Jul to 20 Jul
฿3,110
฿3,639 total
19 Jul - 20 Jul
includes taxes & fees
Stay at this family-friendly hotel in Houston. Enjoy free Wi-Fi, an outdoor pool and breakfast (surcharge). Our guests praise the pool and the helpful staff ...
8/10 Very good! (169 reviews)
"Beautiful hotel. Good amenities. If breakfast was complimentary this would be a 5-star easily! Will definitely book again."
Reviewed on 14 Jul 2026
Hilton Houston Plaza/Medical Center
6633 Travis St Houston TX
The price is ฿3,684 per night from 24 Jul to 25 Jul
฿3,684
฿4,349 total
24 Jul - 25 Jul
includes taxes & fees
Stay at this luxury hotel in Houston. Enjoy free Wi-Fi, 2 restaurants and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in their reviews. ...
8.4/10 Very good! (2,038 reviews)
"I usually don’t leave reviews, but I had to leave one. I just went to Houston for the Dreamcon convention and the next time I come back for next year, I will be also staying at this hotel! The staff are extremely nice and friendly. The rooms are spacious, and the beds are very comfortable! There’s ..."
Reviewed on 14 Jul 2026
Club Quarters Hotel Downtown, Houston
1085 Rusk Street Houston TX
The price is ฿3,888 per night from 15 Jul to 16 Jul
฿3,888
฿4,549 total
15 Jul - 16 Jul
includes taxes & fees
Stay at this business-friendly hotel in Houston. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the restaurant and the helpful staff ...
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
5353 Westheimer Rd Houston TX
Fully refundableReserve now, pay when you stay
The price is ฿4,278 per night from 31 Jul to 1 Aug
฿4,278
฿5,041 total
31 Jul - 1 Aug
includes taxes & fees
Stay at this hotel in Houston. Enjoy an outdoor pool, breakfast (surcharge) and a free local area shuttle. Our guests praise the helpful staff and the clean ...
8.4/10 Very good! (4,279 reviews)
"As a woman solo traveler I felt very safe!"
Reviewed on 14 Jul 2026
Marriott Marquis Houston
1777 Walker Street Houston TX
The price is ฿9,343 per night from 30 Jul to 31 Jul
฿9,343
฿11,900 total
30 Jul - 31 Jul
includes taxes & fees
Stay at this spa hotel in Houston. Enjoy 2 outdoor pools, a full-service spa and 4 restaurants. Our guests praise the pool and the helpful staff in their reviews. ...
9/10 Wonderful! (1,175 reviews)
"Amazing hotel Stayed here after getting married and they couldn’t have been more accommodating."
Reviewed on 14 Jul 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in South Main
Find the best South Main areas for the activities you enjoy most.
Downtown Houston
Gourmet restaurants acclaimed theatres and top sights from Daikin Park to Toyota Center – discover Downtown Houston, a destination also famous for its sports teams.
The Galleria
Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Williams Tower.
Texas Medical Center
Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.
Montrose
Unique features of Montrose include the theatres and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.
Photo by George Zimzores
Open Photo by George Zimzores
Houston Central Business District
If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Downtown Transit Center Station.
