
Search Hotels Near Florida Keys National Marine Sanctuary, Key West
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Our top choices for Florida Keys National Marine Sanctuary hotels

Almond Tree Inn Hotel - Adults Only
Almond Tree Inn Hotel - Adults OnlyDowntown Key West, 0.9 km from Florida Keys National Marine Sanctuary
10.0 out of 10, Exceptional, (1,002 reviews)
The price is ฿12,214
฿13,741 total
includes taxes & fees
26 May - 27 May

The Gardens Hotel
The Gardens HotelDowntown Key West, 0.8 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (1,000 reviews)
The price is ฿9,984
฿11,232 total
includes taxes & fees
11 May - 12 May

Orchid Key Inn - Adults Only
Orchid Key Inn - Adults OnlyUptown - Upper Duval, 0.8 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (1,002 reviews)
The price is ฿12,214
฿13,741 total
includes taxes & fees
26 May - 27 May

Key West Villas
Key West VillasDowntown Key West, 0.8 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (258 reviews)
The price is ฿10,168
฿11,439 total
includes taxes & fees
14 May - 15 May

The Marquesa Hotel
The Marquesa HotelOld Town Key West, 1 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (1,000 reviews)
The price is ฿11,621
฿14,895 total
includes taxes & fees
10 May - 11 May

Simonton Court Historic Inn & Cottages
Simonton Court Historic Inn & CottagesHistoric Seaport, 1 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (941 reviews)
The price is ฿11,021
฿12,399 total
includes taxes & fees
4 May - 5 May

Douglas House - Adults Only
Douglas House - Adults OnlyUptown - Upper Duval, 0.9 km from Florida Keys National Marine Sanctuary
9.6 out of 10, Exceptional, (367 reviews)
The price is ฿6,403
฿7,923 total
includes taxes & fees
3 May - 4 May

Tropical Inn
Tropical InnDowntown Key West, 0.8 km from Florida Keys National Marine Sanctuary
9.6 out of 10, Exceptional, (395 reviews)
The price is ฿7,734
฿9,513 total
includes taxes & fees
3 May - 4 May

The Conch House Heritage Inn
The Conch House Heritage InnOld Town Key West, 1.1 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (166 reviews)
The price is ฿13,130
฿14,771 total
includes taxes & fees
11 May - 12 May

H2O Suites - Adults Only
H2O Suites - Adults OnlyUptown - Upper Duval, 1.1 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (599 reviews)
The price is ฿14,858
฿18,901 total
includes taxes & fees
25 May - 26 May

L'Habitation Guest House
L'Habitation Guest HouseHistoric Seaport, 0.8 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (974 reviews)
The price is ฿6,115
฿6,880 total
includes taxes & fees
3 May - 4 May

Duval House
Duval HouseDowntown Key West, 0.8 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (1,026 reviews)
The price is ฿7,445
฿9,075 total
includes taxes & fees
24 May - 25 May

Island City House Hotel
Island City House HotelHistoric Seaport, 1.2 km from Florida Keys National Marine Sanctuary
9.6 out of 10, Exceptional, (1,004 reviews)
The price is ฿8,795
฿9,895 total
includes taxes & fees
13 May - 14 May

Marrero's Guest Mansion
Marrero's Guest MansionDowntown Key West, 0.7 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (337 reviews)
The price is ฿10,046
฿11,302 total
includes taxes & fees
20 May - 21 May

Caribbean House
Caribbean HouseBahama Village, 0.5 km from Florida Keys National Marine Sanctuary
9.2 out of 10, Wonderful, (351 reviews)
The price is ฿9,980
฿12,037 total
includes taxes & fees
3 May - 4 May

Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly
Alexanders Guesthouse - Adult Exclusive, LGBTQ FriendlyOld Town Key West, 1.7 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (142 reviews)
The price is ฿5,823
฿7,853 total
includes taxes & fees
3 May - 4 May

Santa Maria Suites
Santa Maria SuitesUptown - Upper Duval, 1.3 km from Florida Keys National Marine Sanctuary
9.6 out of 10, Exceptional, (1,000 reviews)
The price is ฿12,269
฿15,987 total
includes taxes & fees
25 May - 26 May

Ambrosia Key West
Ambrosia Key WestOld Town Key West, 1 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (1,002 reviews)
The price is ฿8,200
฿9,225 total
includes taxes & fees
4 May - 5 May

Heron House - Adult Only
Heron House - Adult OnlyDowntown Key West, 0.9 km from Florida Keys National Marine Sanctuary
9.2 out of 10, Wonderful, (1,147 reviews)
The price is ฿4,839
฿6,556 total
includes taxes & fees
7 May - 8 May

Southernmost House - Adult Exclusive
Southernmost House - Adult ExclusiveUptown - Upper Duval, 1.2 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (1,006 reviews)
The price is ฿7,743
฿12,808 total
includes taxes & fees
26 May - 27 May
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Compare popular hotels close to Florida Keys National Marine Sanctuary
Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | |
|---|---|---|---|---|---|---|---|---|
![]() Almond Tree Inn Hotel - Adults Only | 10.0 Exceptional 1,002 reviews | View | ||||||
![]() The Gardens Hotel | 9.8 Exceptional 1,000 reviews | View | ||||||
![]() Orchid Key Inn - Adults Only | 9.8 Exceptional 1,002 reviews | View | ||||||
![]() Key West Villas | 9.8 Exceptional 258 reviews | View | ||||||
![]() The Marquesa Hotel | 9.8 Exceptional 1,000 reviews | View |
Top Florida Keys National Marine Sanctuary Hotel Reviews

Casa Marina Key West, Curio Collection by Hilton
10/10 Excellent













































































