Search Business Hotels in South America

    calendar shield illustration
    Change your mind
    Book hotels with free cancellation
    deals illustration
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    bed illustration
    Be picky
    Search almost a million properties worldwide

South America Accommodation: Most Popular Cities to Stay

Check availability on South America Business Hotels

This weekend
Next weekend

Top South America Business Hotels

Radisson Blu Plaza El Bosque Santiago

4.0 star property
8.8 out of 10, Excellent, (1001)
"Very nice area and modern Hotel, friendly bar and good wine selection. Breakfast was just average, alot of people this weekend. Would book there again for sure."
The price is ฿4,368
฿4,368 total
2 Aug - 3 Aug
Radisson Blu Plaza El Bosque Santiago

Grand Hyatt Sao Paulo

5.0 star property
9.4 out of 10, Exceptional, (1009)
"Good location for shopping."
The price is ฿6,251
฿6,564 total
includes taxes & fees
5 Jul - 6 Jul
Grand Hyatt Sao Paulo

Pullman Santiago Vitacura

5.0 star property
9.0 out of 10, Wonderful, (873)
"Great location and wonderful and accommodating staff. "
The price is ฿3,436
฿3,436 total
2 Aug - 3 Aug
Pullman Santiago Vitacura

NH Collection Medellín Royal

5.0 star property
9.0 out of 10, Wonderful, (1001)
"Good location, lovely property, and helpful customer service."
The price is ฿3,192
฿3,192 total
27 Jul - 28 Jul
NH Collection Medellín Royal

NM Lima Hotel

4.0 star property
9.2 out of 10, Wonderful, (1006)
"Nice appointed hotel. Great location in San Isidro, walkable neighborhood and shopping. "
NM Lima Hotel

Pullman Lima San Isidro

4.0 star property
9.2 out of 10, Wonderful, (776)
"nice place"
The price is ฿4,347
฿4,782 total
27 Jul - 28 Jul
Pullman Lima San Isidro

Hotel Plaza El Bosque Ebro

4.0 star property
9.0 out of 10, Wonderful, (1001)
"We had a great experience "
The price is ฿4,631
฿4,955 total
5 Jul - 6 Jul
Hotel Plaza El Bosque Ebro

Hotel Madero Buenos Aires

4.5 star property
9.2 out of 10, Wonderful, (1000)
"The amenities and breakfast was delicious. Also the good security at the hotel"
The price is ฿5,795
฿5,892 total
1 Aug - 2 Aug
Hotel Madero Buenos Aires

Regal Pacific Buenos Aires

4.5 star property
8.8 out of 10, Excellent, (1000)
"Excelente "
Regal Pacific Buenos Aires

GHL Hotel Capital

4.0 star property
9.2 out of 10, Wonderful, (1217)
"Breakfast was excellent "
The price is ฿2,981
฿2,981 total
26 Jul - 27 Jul
GHL Hotel Capital
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Frequently asked questions

Why book your business-friendly hotel in South America with Expedia?
Here at Expedia, our top task is to help you choose the perfect stay at the right price. From luxurious, corporate-friendly getaways to affordable hotels filled with handy amenities, you'll have your next work trip organised in just a few clicks.
How can I find cheap business-friendly hotels in South America?
When work takes you to South America, our "business friendly" filter will help you find the right hotel. From fast WiFi to meeting rooms and workspaces, they have the amenities you need to do your job. You can also narrow your search by your budget and preferred star rating to view the cheapest properties.