Flight Destinations in Panama

View ฿6,220 flight on Sun, 1 Feb 2026Opens in a new window

Popular airlines to Panama

  • Avianca

    Avianca

  • American Airlines

    American Airlines

  • United

    United

  • Copa

    Copa

  • Delta

    Delta

  • Aeromexico

    Aeromexico

  • KLM

    KLM

  • notification illustration

    Be in the know

    Get alerts if flight prices drop or rise*
  • deals illustration

    Book smarter

    Save up to 40% on select hotels after you book a flight*
  • trophy illustration

    Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheap round-trip flights to Panama

Prices were available within the past 7 days and start at ฿6,220 for one-way flights and ฿11,980 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

avianca
Fri, 30 Jan - Mon, 2 Feb
MEX
Mexico City
PTY
Panama City
฿11,980 Return, found 4 hours ago
฿11,980
Return
found 4 hours ago
Select avianca flight, departing Fri, 30 Jan from Mexico City to Panama City, returning Mon, 2 Feb, priced at ฿11,980 found 4 hours ago
avianca
Fri, 30 Jan - Mon, 2 Feb
MEX
Mexico City
PTY
Panama City
฿12,030 Return, found 4 hours ago
฿12,030
Return
found 4 hours ago
Select avianca flight, departing Fri, 30 Jan from Mexico City to Panama City, returning Mon, 2 Feb, priced at ฿12,030 found 4 hours ago
avianca
Sat, 31 Jan - Mon, 2 Feb
MEX
Mexico City
PTY
Panama City
฿12,355 Return, found 8 hours ago
฿12,355
Return
found 8 hours ago
Select avianca flight, departing Sat, 31 Jan from Mexico City to Panama City, returning Mon, 2 Feb, priced at ฿12,355 found 8 hours ago
avianca
Fri, 30 Jan - Mon, 2 Feb
MEX
Mexico City
PTY
Panama City
฿12,575 Return, found 4 hours ago
฿12,575
Return
found 4 hours ago
Select avianca flight, departing Fri, 30 Jan from Mexico City to Panama City, returning Mon, 2 Feb, priced at ฿12,575 found 4 hours ago
avianca
Fri, 30 Jan - Mon, 2 Feb
MEX
Mexico City
PTY
Panama City
฿14,185 Return, found 4 hours ago
฿14,185
Return
found 4 hours ago
Select avianca flight, departing Fri, 30 Jan from Mexico City to Panama City, returning Mon, 2 Feb, priced at ฿14,185 found 4 hours ago
avianca
Fri, 30 Jan - Mon, 2 Feb
MEX
Mexico City
PTY
Panama City
฿14,235 Return, found 4 hours ago
฿14,235
Return
found 4 hours ago
Select avianca flight, departing Fri, 30 Jan from Mexico City to Panama City, returning Mon, 2 Feb, priced at ฿14,235 found 4 hours ago
Copa
Fri, 30 Jan - Mon, 2 Feb
MEX
Mexico City
PTY
Panama City
฿14,735 Return, found 4 hours ago
฿14,735
Return
found 4 hours ago
Select Copa flight, departing Fri, 30 Jan from Mexico City to Panama City, returning Mon, 2 Feb, priced at ฿14,735 found 4 hours ago
Delta
Wed, 18 Feb - Wed, 25 Feb
LAX
Los Angeles
PTY
Panama City
฿24,155 Return, found 1 day ago
฿24,155
Return
found 1 day ago
Select Delta flight, departing Wed, 18 Feb from Los Angeles to Panama City, returning Wed, 25 Feb, priced at ฿24,155 found 1 day ago
Aeromexico
Thu, 19 Mar - Sun, 22 Mar
MEX
Mexico City
PTY
Panama City
฿25,000 Return, found 8 hours ago
฿25,000
Return
found 8 hours ago
Select Aeromexico flight, departing Thu, 19 Mar from Mexico City to Panama City, returning Sun, 22 Mar, priced at ฿25,000 found 8 hours ago
United
Wed, 18 Feb - Wed, 25 Feb
LAX
Los Angeles
PTY
Panama City
฿25,290 Return, found 1 day ago
฿25,290
Return
found 1 day ago
Select United flight, departing Wed, 18 Feb from Los Angeles to Panama City, returning Wed, 25 Feb, priced at ฿25,290 found 1 day ago

About Panama

Expedia offers flights to Panama to meet every traveller's needs. Whatever your flight need - Expedia has the flight for you. So choose from flights to Panama or destinations around the world and discover how easy it is to make your flight reservations on Expedia.

Frequently asked questions

How do I find cheap flights to Panama that have flexible change policies?
By using our clever "No change fee" filter, that's how. All you have to do is enter your origin, destination and dates, click the "Search" button, then click the checkbox directly below the "Flexible change policies" heading (left-hand side of your screen). Expedia makes it a snap to find inexpensive, flexible airfares to Panama.
Which airlines fly to Panama?
You can choose from a good variety of airlines with flights into or near Panama. A few of your options are:

  • Copa Airlines - 772 flights to or near Panama each month, including 772 flights to Tocumen Intl. Airport (PTY) per month.
  • United Airlines - 91 flights to or near Panama each month, including 91 flights to Tocumen Intl. Airport (PTY) per month.
  • American Airlines - 60 flights to or near Panama each month, including 60 flights to Tocumen Intl. Airport (PTY) per month.

How can I find cheap tickets to Panama?
In the last seven days, ฿11,980 was the best price for a flight to Panama. For even greater savings, book well ahead of time and be flexible with your travel dates. Search for your trip to Panama, then see prices for nearby days by clicking on our "flexible dates" link.
How much is a flight to Panama?
You could have scored a round-trip flight to Panama from anywhere between ฿11,980 and ฿40,770 in the last seven days. For one-way journeys departing from Los Angeles (LAX), the lowest price during this period was just ฿6,220.
What are the most popular airports to fly into in Panama?
Panama's main entryway is Tocumen Intl. Airport (PTY). Get your awesome journey underway by booking a ticket on one of the 963 flights every month to this destination.
How much is a plane ticket to Panama?
In the last seven days, plane fares to Panama ranged from ฿11,980 to ฿40,770.
What is the best time to go to Panama?
San Miguelito, Panama's most well-known city, is a superb location to check out at anytime. Not into the cold? Then head here from June 20 onward in summer, when temperatures fluctuate from 24ºC to 29ºC. February, March and May is when San Miguelito attracts the biggest crowds.
What months are the cheapest to book a flight to Panama?
To score a fabulous deal to Panama, book sometime in February when the prices are at their cheapest. When's the most expensive time? In the U.S, it's December.

Trending flights to Panama

These prices were available within the past 7 days. Prices quoted are per person, return, for the period specified. Prices and availability are subject to change. Additional terms apply.

EVA Airways
Sat, 24 Jan - Wed, 28 Jan
BKK
Bangkok
PTY
Panama City
฿40,770 Return, found 10 hours ago
฿40,770
Return
found 10 hours ago
Select EVA Airways flight, departing Sat, 24 Jan from Bangkok to Panama City, returning Wed, 28 Jan, priced at ฿40,770 found 10 hours ago
*Available to Expedia members.