
Panama Packages (Flight + Hotel)
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
Better together
Find the right fit
Rest easy
Top destinations in Panama

Panama City
Panama Holiday
While Panama is perhaps best known for its mighty canal, there’s so much more to this Central American country. Visitors will also be wowed by lush rainforests, idyllic beaches, rich indigenous culture and a unique colonial history.
Panama Hotel + Flights
Expedia has 3,347 hotels available here starting at ฿4,131 a night. But if you want to save some serious money, combine your hotel and flights into a Panama Holiday Package. You can also add car rental and activities to your booking to create an unforgettable getaway. With the dollars you save, why not book a tour and visit island paradises or taste famous local flavours like ceviche?
Your Panama Holiday Itinerary
Day 1-2: Start your adventure in the national capital, Panama City, and head straight to Casco Viejo (the Old Quarter). Wander narrow cobblestone streets and discover colourful Spanish colonial houses, beautiful churches and an impressive gastronomic scene. Plan a day trip to the Panama Canal to watch mammoth ships slip through the Miraflores Locks.
Day 3-5: Stay on some of the world’s most spectacular islands in San Blas. Owned and operated by the Kuna people, this untouched paradise on the Caribbean side of Panama is the perfect place to live out your Robinson Crusoe fantasies.
Day 6-8: Head back to Panama City and fly to the mountain town of Boquete. A top destination for outdoor lovers, it offers jungle hikes, whitewater rafting, canopy tours, zip lining and more.
Panama Information
Party with the locals at Carnival, Panama’s largest annual celebration. You’ll find the biggest events in Panama City and Las Tablas.
If you’ll be spending most of your time in the nation’s capital, check out our Panama City Holiday PackagesOpens in a new window.
Want to really experience the carefree vibe of this Latin American gem? Book one of our Panama All Inclusive Resorts and say adios to holiday planning stress.
Top hotels in Panama

Hotel Riu Plaza Panama
Great hotel for the price. Nice pool and the included breakfast was a plus. It was clean and staff was nice except for the service desk who appeared to be annoyed with me asking for wash cloths everyday since they failed at leaving any or not enough for me and my daughter. Other than that I had no ...
Reviewed on 20 Oct 2025

Crowne Plaza Panama Airport by IHG
The restaurant was very clean staff helpful but bellboy didn’t return key card. Nobody answered phone when I called operator or front desk
Reviewed on 17 Oct 2025

Gran Evenia Bijao & Convention Center
Puertas de los baños....ascensores más rápidos.....
Reviewed on 12 Oct 2025
Frequently asked questions
Popular places to visit
Colon Free Zone
During your trip to Colon, you can do some window-shopping at Colon Free Zone.
What to do in Panama

Panama City: Poin Glass Observation Deck Ticket with VR Tour

Archaeological Site. Admission ticket to Panama La Vieja
