Panama Packages (Flight + Hotel)

Book a Hotel + Flight or Car together to unlock savings

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    Save up to ฿4,531 when you book a flight and hotel together*

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Top destinations in Panama

Panama Holiday

While Panama is perhaps best known for its mighty canal, there’s so much more to this Central American country. Visitors will also be wowed by lush rainforests, idyllic beaches, rich indigenous culture and a unique colonial history.

Panama Hotel + Flights

Expedia has 3,347 hotels available here starting at ฿4,131 a night. But if you want to save some serious money, combine your hotel and flights into a Panama Holiday Package. You can also add car rental and activities to your booking to create an unforgettable getaway. With the dollars you save, why not book a tour and visit island paradises or taste famous local flavours like ceviche?

Your Panama Holiday Itinerary

  • Day 1-2: Start your adventure in the national capital, Panama City, and head straight to Casco Viejo (the Old Quarter). Wander narrow cobblestone streets and discover colourful Spanish colonial houses, beautiful churches and an impressive gastronomic scene. Plan a day trip to the Panama Canal to watch mammoth ships slip through the Miraflores Locks.

  • Day 3-5: Stay on some of the world’s most spectacular islands in San Blas. Owned and operated by the Kuna people, this untouched paradise on the Caribbean side of Panama is the perfect place to live out your Robinson Crusoe fantasies.

  • Day 6-8: Head back to Panama City and fly to the mountain town of Boquete. A top destination for outdoor lovers, it offers jungle hikes, whitewater rafting, canopy tours, zip lining and more.

Panama Information

  • Party with the locals at Carnival, Panama’s largest annual celebration. You’ll find the biggest events in Panama City and Las Tablas.

  • If you’ll be spending most of your time in the nation’s capital, check out our Panama City Holiday PackagesOpens in a new window.

  • Want to really experience the carefree vibe of this Latin American gem? Book one of our Panama All Inclusive Resorts and say adios to holiday planning stress.

Top hotels in Panama

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is ฿3,755 per night from 9 Nov to 10 Nov
฿3,755
฿4,131 total
9 Nov - 10 Nov
includes taxes & fees
9/10 Wonderful! (4,424 reviews)
Great hotel for the price. Nice pool and the included breakfast was a plus. It was clean and staff was nice except for the service desk who appeared to be annoyed with me asking for wash cloths everyday since they failed at leaving any or not enough for me and my daughter. Other than that I had no ...

Reviewed on 20 Oct 2025

Hotel Riu Plaza Panama
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz, Corregimineto De Tocumen Hacia El, Tocumen, Panama
Fully refundable
The price is ฿3,967 per night from 1 Nov to 2 Nov
฿3,967
฿4,363 total
1 Nov - 2 Nov
includes taxes & fees
8.4/10 Very Good! (2,251 reviews)
The restaurant was very clean staff helpful but bellboy didn’t return key card. Nobody answered phone when I called operator or front desk

Reviewed on 17 Oct 2025

Crowne Plaza Panama Airport by IHG
Gran Evenia Bijao & Convention Center

Gran Evenia Bijao & Convention Center

3.5 out of 5
Carretera Interamericana km 108, Rio Hato
The price is ฿4,533 per night from 30 Oct to 31 Oct
฿4,533
฿4,986 total
30 Oct - 31 Oct
includes taxes & fees
7.8/10 Good! (991 reviews)
Puertas de los baños....ascensores más rápidos.....

Reviewed on 12 Oct 2025

Gran Evenia Bijao & Convention Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Panama holiday package cost?
Custom build your Panama holiday package from a low . Choose from any combination of rental cars, flights and hotels to pull together the trip you've been dreaming about. Remember to add on some activities and experiences!
How do I get a cheap travel package to Panama?
One of the easiest ways to save cash (and time) is to combine your bookings with Expedia. Hotels, flights, rental cars and activities — we've got them all. Select the combination that suits you and watch your savings stack up. Of course, a package deal is never one-size-fits-all. That's why we offer over 550 airlines and 1,000,000 hotels worldwide, which lets you customize your Panama holiday.
Where should I stay in Panama?
Panama City is a great place to visit. It draws in many visitors who come to check out its biggest sights, such as Bridge of the Americas and Miraflores Locks.
What are the top hotels in Panama?
When it comes to hotels in Panama City, Hotel Riu Plaza Panama and Crowne Plaza Panama Airport, an IHG Hotel are two terrific options. If you're also visiting Bocas del Toro, Playa Tortuga Hotel Beach And Resort and Azul Paradise will make you feel at home.
How far in advance should I book my Panama holiday?
It's difficult to pick the ideal time for airfares, but we usually say the earlier, the better. Most international journeys on Expedia become available up to 12 months in advance. If you're booking last minute, fear not. Discounted prices appear from time to time just weeks before departure dates.
What does an Expedia Panama travel package include?
Hotels, rental cars and flights, or any combination of them — it's up to you! Whether you're venturing to Panama with the kids or travelling solo, there's a package to fit your budget and style. Once you've made your booking, why not add on one or two tours or activities?
What should I know before booking a Panama travel package?
A travel package can be customized for your budget and is a terrific way to make your hard-earned dollars stretch further. How much you include is up to you. Rental cars, hotels and flights — come up with a combination that suits your plans.
Can I choose my airline with a Panama Expedia holiday package?
Yes — and it's simple too. Expedia has access to more than 550 partner airlines all over the world. Our packages give you the flexibility to pick from available flights, hotels and activities that fit your needs.
If I'm not able to travel, can I cancel my Panama holiday package?
Because we know life is full of surprises, the answer is yes. For further information, head to our Customer Service Portal. But generally speaking, if you've made your booking in the last 24 hours, you may be able to change or cancel it for free. Your airline, hotel or car rental company may impose a fee if you made your booking a while ago.

Popular places to visit

What to do in Panama

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.