Uptown Travel Guide
Collinsville
Stay near popular Uptown attractions
Things to do
St. Louis & Gateway Arch NP Self Guided Walk & Drive Audio Tour
฿557
per traveller
St. Louis Ghost Tour: Sinister Sins & Shadows
฿787
per adult
100% of travellers recommend
Gateway Arch National Park Self Guided Audio Walking Tour
฿492
per traveller
St. Louis: Museum of Illusions Entry Ticket
฿1,148
per adult
90% of travellers recommend
Top hotels in Uptown
Hyatt Regency St. Louis at The Arch
315 Chestnut St St. Louis MO
The price is ฿5,007 per night from 4 Oct to 5 Oct
฿5,007
฿5,904 total
4 Oct - 5 Oct
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, 3 restaurants and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (4,231 reviews)
"It was a beautiful hotel."
Reviewed on 8 Sept 2026
Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue St. Louis MO
The price is ฿3,412 per night from 5 Oct to 6 Oct
฿3,412
฿3,983 total
5 Oct - 6 Oct
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the pool ...
Drury Plaza Hotel St. Louis at the Arch
2 South 4th Street St. Louis MO
The price is ฿4,440 per night from 5 Oct to 6 Oct
฿4,440
฿5,192 total
5 Oct - 6 Oct
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and 2 hot tubs. Our guests praise the breakfast and the pool in their reviews. ...
9.6/10 Exceptional! (3,745 reviews)
"Great breakfast"
Reviewed on 8 Sept 2026
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
3550 Samuel Sheppard Drive St. Louis MO
The price is ฿4,156 per night from 2 Oct to 3 Oct
฿4,156
฿4,901 total
2 Oct - 3 Oct
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, a rooftop terrace and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.8/10 Excellent! (1,157 reviews)
"Love the art work and the moody colors of the rooms."
Reviewed on 8 Sept 2026
Hampton Inn St. Louis-Downtown (At the Gateway Arch)
333 Washington Ave St. Louis MO
Fully refundableReserve now, pay when you stay
The price is ฿4,019 per night from 14 Sept to 15 Sept
฿4,019
฿4,699 total
14 Sept - 15 Sept
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,395 reviews)
"Stayed 1 night with my spouse and teen. Proximity to City museum was good, walkable if weather was good. Parking was less expensive than at similar nearby hotels. We had an abundance of towels in our room which was nice. Dislikes: our room was a little rundown, particularly the bathroom. Fixture ..."
Reviewed on 7 Sept 2026
21C Museum Hotel St Louis
1528 Locust street St. Louis MO
The price is ฿4,729 per night from 4 Oct to 5 Oct
฿4,729
฿5,694 total
4 Oct - 5 Oct
includes taxes & fees
Stay at this luxury hotel in St. Louis. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the pool and the restaurant in their reviews. ...
9/10 Wonderful! (2,101 reviews)
"Love this hotel. Great stay for our entire family."
Reviewed on 8 Sept 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Uptown
Find the best Uptown areas for the activities you enjoy most.
Eastport
While visiting Eastport, you might make a stop by sights like Gateway Conference Center and Splash City Family Waterpark.
Mulberry Hills
Though Mulberry Hills may not have many top sights, you can venture to the surrounding area to see attractions like Gateway Conference Center and FanDuel Sportsbook and Horse Racing.
Historic Downtown Collinsville
Though Historic Downtown Collinsville may not have many top sights, you can venture to the surrounding area to see attractions like Gateway Conference Center and Splash City Family Waterpark.
