Uptown Travel Guide
Collinsville
Stay near popular Uptown attractions
Things to do
St. Louis Narrated Trolley Tour
฿984
per adult
90% of travellers recommend
St. Louis & Gateway Arch NP Self Guided Walk & Drive Audio Tour
฿557
per traveller
St. Louis Ghost Tour: Sinister Sins & Shadows
฿787
per adult
100% of travellers recommend
Gateway Arch National Park Self Guided Audio Walking Tour
฿492
per traveller
Self Guided Walk & Drive Audio Tour St. Louis & Gateway Arch NP
฿492
per traveller
Top hotels in Uptown
Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
The price is ฿3,113 per night from 11 Oct to 12 Oct
฿3,113
฿3,634 total
11 Oct - 12 Oct
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the pool ...
8.8/10 Excellent! (3,400 reviews)
"Breakfast was great"
Reviewed on 14 Sept 2026
Hyatt Regency St. Louis at The Arch
315 Chestnut St St. Louis MO
The price is ฿5,027 per night from 4 Oct to 5 Oct
฿5,027
฿5,928 total
4 Oct - 5 Oct
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, 3 restaurants and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms ...
Drury Plaza Hotel St. Louis at the Arch
2 South 4th Street St. Louis MO
The price is ฿4,461 per night from 4 Oct to 5 Oct
฿4,461
฿5,217 total
4 Oct - 5 Oct
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and 2 hot tubs. Our guests praise the breakfast and the pool in their reviews. ...
9.6/10 Exceptional! (3,744 reviews)
"Breakfast is just so typical but the staff is wonderful."
Reviewed on 13 Sept 2026
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
3550 Samuel Sheppard Drive St. Louis MO
The price is ฿4,174 per night from 2 Oct to 3 Oct
฿4,174
฿4,922 total
2 Oct - 3 Oct
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, a rooftop terrace and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.8/10 Excellent! (1,164 reviews)
"Close to venues for concerts for walking distance. Parking was on-site. We were early enough to get a spot, but it's shared with the public, Eclectic little spot, loved it."
Reviewed on 13 Sept 2026
Drury Plaza Hotel St. Louis Union Station
201 S 20th St St. Louis MO
The price is ฿4,461 per night from 20 Sept to 21 Sept
฿4,461
฿5,306 total
20 Sept - 21 Sept
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful staff ...
21C Museum Hotel St Louis
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
The price is ฿4,748 per night from 11 Oct to 12 Oct
฿4,748
฿5,717 total
11 Oct - 12 Oct
includes taxes & fees
Stay at this luxury hotel in St. Louis. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the pool and the restaurant in their reviews. ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Uptown
Find the best Uptown areas for the activities you enjoy most.
Eastport
While visiting Eastport, you might make a stop by sights like Gateway Conference Center and Splash City Family Waterpark.
Mulberry Hills
Though Mulberry Hills may not have many top sights, you can venture to the surrounding area to see attractions like World's Largest Catsup Bottle and Gateway Conference Center.
Historic Downtown Collinsville
Though Historic Downtown Collinsville may not have many top sights, you can venture to the surrounding area to see attractions like World's Largest Catsup Bottle and Gateway Conference Center.
