Uptown Travel Guide
Collinsville
Stay near popular Uptown attractions
Things to do
St. Louis & Gateway Arch NP Self Guided Walk & Drive Audio Tour
฿557
per traveller
St. Louis Ghost Tour: Sinister Sins & Shadows
฿787
per adult
100% of travellers recommend
Gateway Arch National Park Self Guided Audio Walking Tour
฿492
per traveller
Self Guided Walk & Drive Audio Tour St. Louis & Gateway Arch NP
฿492
per traveller
Top hotels in Uptown
Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
The price is ฿3,147 per night from 11 Oct to 12 Oct
฿3,147
฿3,674 total
11 Oct - 12 Oct
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the pool ...
Hyatt Regency St. Louis at The Arch
315 Chestnut St St. Louis MO
The price is ฿5,062 per night from 2 Oct to 3 Oct
฿5,062
฿5,969 total
2 Oct - 3 Oct
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, 3 restaurants and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms ...
Drury Plaza Hotel St. Louis at the Arch
2 South 4th Street St. Louis MO
The price is ฿4,492 per night from 16 Oct to 17 Oct
฿4,492
฿5,253 total
16 Oct - 17 Oct
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and 2 hot tubs. Our guests praise the breakfast and the pool in their reviews. ...
9.6/10 Exceptional! (3,751 reviews)
"Place is amazing. Great location, great breakfast, great kickbacks. Staff was amazing. Especially Lorraine and Shirley had the best attitude and smile. I will definitely be staying a Drury places."
Reviewed on 17 Sept 2026
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
3550 Samuel Sheppard Drive St. Louis MO
The price is ฿3,669 per night from 1 Oct to 2 Oct
฿3,669
฿4,327 total
1 Oct - 2 Oct
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, a rooftop terrace and breakfast (surcharge). Our guests praise the helpful staff and the ...
Drury Plaza Hotel St. Louis Union Station
201 S 20th St St. Louis MO
The price is ฿4,492 per night from 28 Sept to 29 Sept
฿4,492
฿5,343 total
28 Sept - 29 Sept
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful staff ...
21C Museum Hotel St Louis
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
The price is ฿4,781 per night from 11 Oct to 12 Oct
฿4,781
฿5,756 total
11 Oct - 12 Oct
includes taxes & fees
Stay at this luxury hotel in St. Louis. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the pool and the restaurant in their reviews. ...
9/10 Wonderful! (2,112 reviews)
"Interesting concept, but poorly executed. Unfortunately, this did not feel like a true 4-star hotel experience. The location can be convenient if you are visiting the Gateway Arch or attending an event downtown, and for us it worked well because we could walk to the AC/DC concert. Otherwise, there ..."
Reviewed on 16 Sept 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Uptown
Find the best Uptown areas for the activities you enjoy most.
Eastport
While visiting Eastport, you might make a stop by sights like Gateway Conference Center and Splash City Family Waterpark.
Mulberry Hills
Though Mulberry Hills may not have many top sights, you can venture to the surrounding area to see attractions like World's Largest Catsup Bottle and Gateway Conference Center.
Historic Downtown Collinsville
Though Historic Downtown Collinsville may not have many top sights, you can venture to the surrounding area to see attractions like World's Largest Catsup Bottle and Gateway Conference Center.
