Uptown Travel Guide
Collinsville
Stay near popular Uptown attractions
Things to do
St. Louis & Gateway Arch NP Self Guided Drive & Walk Audio Tour
฿562
per traveller
St. Louis Ghost Tour: Sinister Sins & Shadows
฿794
per adult
100% of travellers recommend
Gateway Arch National Park Self Guided Audio Walking Tour
฿496
per traveller
St. Louis: Museum of Illusions Entry Ticket
฿1,158
per adult
88% of travellers recommend
Top hotels in Uptown
Hyatt Regency St. Louis at The Arch
315 Chestnut St St. Louis MO
The price is ฿5,007 per night from 7 Sept to 8 Sept
฿5,007
฿5,904 total
7 Sept - 8 Sept
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, 3 restaurants and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms ...
Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue St. Louis MO
The price is ฿3,440 per night from 4 Oct to 5 Oct
฿3,440
฿4,016 total
4 Oct - 5 Oct
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the pool ...
9/10 Wonderful! (3,375 reviews)
"This location is our go to hotel every time we come in town. This was our first time getting a suite and it was very nice. I love how roomy the bathroom was plus there was a tub-shower and a shower which was very nice. I would definitely recommend this hotel and I would book this hotel again. The ..."
Reviewed on 5 Sept 2026
Drury Plaza Hotel St. Louis at the Arch
2 South 4th Street St. Louis MO
The price is ฿4,444 per night from 4 Oct to 5 Oct
฿4,444
฿5,196 total
4 Oct - 5 Oct
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and 2 hot tubs. Our guests praise the breakfast and the pool in their reviews. ...
9.6/10 Exceptional! (3,734 reviews)
"It was an excellent stay. Room clean, everything great. The breakfast top level."
Reviewed on 5 Sept 2026
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
3550 Samuel Sheppard Drive St. Louis MO
The price is ฿4,158 per night from 2 Oct to 3 Oct
฿4,158
฿4,903 total
2 Oct - 3 Oct
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, a rooftop terrace and breakfast (surcharge). Our guests praise the helpful staff and the ...
Hampton Inn St. Louis-Downtown (At the Gateway Arch)
333 Washington Ave St. Louis MO
The price is ฿4,022 per night from 13 Sept to 14 Sept
฿4,022
฿4,703 total
13 Sept - 14 Sept
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the helpful ...
21C Museum Hotel St Louis
1528 Locust street St. Louis MO
The price is ฿4,729 per night from 27 Sept to 28 Sept
฿4,729
฿5,694 total
27 Sept - 28 Sept
includes taxes & fees
Stay at this luxury hotel in St. Louis. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the pool and the restaurant in their reviews. ...
9/10 Wonderful! (2,092 reviews)
"Excellent hotel , friendly , loved all public area including the pool"
Reviewed on 5 Sept 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Uptown
Find the best Uptown areas for the activities you enjoy most.
Eastport
While visiting Eastport, you might make a stop by sights like Gateway Conference Center and Splash City Family Waterpark.
Mulberry Hills
Though Mulberry Hills may not have many top sights, you can venture to the surrounding area to see attractions like Gateway Conference Center and Stonewolf Golf Course.
Historic Downtown Collinsville
Though Historic Downtown Collinsville may not have many top sights, you can venture to the surrounding area to see attractions like Gateway Conference Center and Splash City Family Waterpark.
