A vibrant mural on a building, depicting a large figure with a heart-shaped halo, surrounded by various characters in colorful attire.

5 Stars Hotels in Mission District

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Check availability on Mission District 5 Star Hotels

Next weekend
2 Oct - 4 Oct
In two weeks
9 Oct - 11 Oct

Our top choices for Mission District 5-star hotels

A rooftop terrace with a city skyline, a fountain, and outdoor seating.

1. Fairmont San Francisco

Fairmont San Francisco
5.0 star property
Downtown San Francisco
9.2 out of 10, Wonderful, (1,602 reviews)
"Perfect location. Beautiful hotel!"
United States
virginia
The price is ฿11,018
฿14,735 total
includes taxes & fees
11 Oct - 12 Oct
Fairmont San Francisco
A terrace with a view, featuring a table and chairs, a potted plant, and a decorative lantern.

2. Claremont Resort & Club

Claremont Resort & Club
5.0 star property
Claremont Hills
9.0 out of 10, Wonderful, (1,159 reviews)
"My sister had a wonderful stay, just a perfect location!"
United States
Jacqueline
The price is ฿11,388
฿15,326 total
includes taxes & fees
28 Sept - 29 Sept
Claremont Resort & Club
A bar area with a marble countertop, leather bar stools, and shelves stocked with bottles and glasses.

3. Taj Campton Place

Taj Campton Place
5.0 star property
Union Square
9.2 out of 10, Wonderful, (1,001 reviews)
"Wonderful service, convenient, delicious food!"
United States
Vince
The price is ฿7,372
฿9,839 total
includes taxes & fees
1 Oct - 2 Oct
Taj Campton Place
A grand hall with a high arched ceiling and chandeliers, featuring multiple dining tables and chairs arranged for service.

4. Palace Hotel, a Luxury Collection Hotel, San Francisco

Palace Hotel, a Luxury Collection Hotel, San Francisco
5.0 star property
Downtown San Francisco
9.2 out of 10, Wonderful, (1,002 reviews)
"Beautiful historic hotel. Resort fee comes with two Moma tickets."
United States
Sean
The price is ฿11,689
฿15,329 total
includes taxes & fees
23 Oct - 24 Oct
Palace Hotel, a Luxury Collection Hotel, San Francisco
A grand building with classical architecture, featuring columns, detailed carvings, and a large entrance.

5. The Ritz-Carlton, San Francisco

The Ritz-Carlton, San Francisco
5.0 star property
Downtown San Francisco
9.4 out of 10, Exceptional, (1,002 reviews)
"Close to everything and the staff was amazing!"
United States
Simona
The price is ฿13,594
฿17,608 total
includes taxes & fees
23 Oct - 24 Oct
The Ritz-Carlton, San Francisco
A restaurant with wooden flooring, black chairs, white tables, hanging plants, and pendant lights.

6. 1 Hotel San Francisco

1 Hotel San Francisco
5.0 star property
Downtown San Francisco
9.2 out of 10, Wonderful, (620 reviews)
"The hotel, the room and the restaurant were very clean. The staff very helpful and it’s very well located."
United States
Gloria
The price is ฿14,981
฿19,518 total
includes taxes & fees
23 Oct - 24 Oct
1 Hotel San Francisco
A rooftop terrace with tables and potted plants, overlooking a cityscape with a prominent tower and a bridge.

7. Four Seasons Hotel San Francisco at Embarcadero

Four Seasons Hotel San Francisco at Embarcadero
5.0 star property
Downtown San Francisco
9.6 out of 10, Exceptional, (1,001 reviews)
"Great hotel, well located, good restaurant downstairs. Only drawback is slow elevators"
United States
Ariane
The price is ฿15,750
฿18,537 total
includes taxes & fees
23 Oct - 24 Oct
Four Seasons Hotel San Francisco at Embarcadero
A rooftop terrace with outdoor seating, a view of the city skyline, and modern buildings in the background.

8. Four Seasons Hotel San Francisco

Four Seasons Hotel San Francisco
5.0 star property
Downtown San Francisco
9.4 out of 10, Exceptional, (1,004 reviews)
"Great and helpful staff"
United States
Nirav
The price is ฿15,892
฿20,669 total
includes taxes & fees
11 Oct - 12 Oct
Four Seasons Hotel San Francisco
A balcony with a view of a tall building, a tree, and a table with chairs.

9. The Huntington Hotel

The Huntington Hotel
5.0 star property
Downtown San Francisco
9.4 out of 10, Exceptional, (36 reviews)
"Perfect weekend stay. A great hotel.....happy it's back in operation after many years! Highly recommend!"
United States
Steven
The price is ฿26,676
฿33,165 total
includes taxes & fees
3 Oct - 4 Oct
The Huntington Hotel
A modern hotel with a glass facade, a covered entrance, and a sign indicating it is a Marriott hotel.

10. The St. Regis San Francisco

The St. Regis San Francisco
5.0 star property
Downtown San Francisco
9.4 out of 10, Exceptional, (740 reviews)
"Great place"
United States
Christopher
The price is ฿15,458
฿19,720 total
includes taxes & fees
2 Oct - 3 Oct
The St. Regis San Francisco
A grand entrance with a large archway, a staircase, and two wall-mounted light fixtures.

11. Hotel Drisco

Hotel Drisco
5.0 star property
Pacific Heights
9.8 out of 10, Exceptional, (478 reviews)
"Fun spot to enjoy the Pacific Heights section of SF. Great place and wonderful staff. Enjoyed out entire, albeit short stay."
United States
Geoffrey
The price is ฿26,112
฿30,371 total
includes taxes & fees
25 Oct - 26 Oct
Hotel Drisco
A covered outdoor dining area with a wooden deck, a table set for two, and a view of the sea and mountains in the background.

12. Fairmont Heritage Place, Ghirardelli Square

Fairmont Heritage Place, Ghirardelli Square
5.0 star property
Fisherman's Wharf
9.4 out of 10, Exceptional, (415 reviews)
"Excellent location and rooms - great space for families. Very helpful and friendly staff."
United States
Janelle
The price is ฿25,675
฿30,168 total
includes taxes & fees
11 Oct - 12 Oct
Fairmont Heritage Place, Ghirardelli Square
A historic building with ornate architectural details, large windows, and a well-lit entrance.

13. Sutter Mansion

Sutter Mansion
5.0 star property
Western Addition
9.4 out of 10, Exceptional, (248 reviews)
"The location is so beautiful - a Victorian style mansion. the staff were all so kind and polite and room was lovely. Breakfast was delicious as well."
United States
Stewart
The price is ฿11,943
฿15,348 total
includes taxes & fees
4 Oct - 5 Oct
Sutter Mansion
A modern living room with a black door, a sofa with patterned cushions, a coffee table, and a view of a street with buildings and parked cars.

14. Dimond Abode Vacation Rental

Dimond Abode Vacation Rental
5.0 star property
Dimond
10.0 out of 10, Exceptional, (2 reviews)
"The unit was extremely clean and having access to a garage was definitely a plus for our stay! Nice touches, especially coffee / tea , snacks, and a well equipped kitchen made us feel welcomed the minute we stepped through the door. A+"
United States
Camille
Dimond Abode Vacation Rental
A modern kitchen with stainless steel appliances, a flat-screen TV, and a bar area with bar stools.

15. Dimond Abode Vacation Rental 3428

Dimond Abode Vacation Rental 3428
5.0 star property
Dimond
9.6 out of 10, Exceptional, (7 reviews)
"Cleanliness, amenities, staff. It was a really great stay."
United States
Phyllis
Dimond Abode Vacation Rental 3428
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Mission District.
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

2500 Mason St San Francisco CA
The price is ฿4,596 per night from 18 Oct to 19 Oct
฿4,596
฿6,784 total
18 Oct - 19 Oct
includes taxes & fees
9/10 Wonderful! (7,673 reviews)
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Top Mission District Hotel Reviews

Frequently asked questions

What are the best 5-star hotels in Mission District?
According to reviews by Expedia customers, Mansion on Sutter is one of the best properties for an indulgent escape in the San Francisco neighbourhood of Mission District. Looking for more 5-star hotels around the area? The St. Regis San Francisco and Taj Campton Place will meet your high-end desires.
How much does it cost to stay in a 5-star hotel in Mission District?
How much you pay for a 5-star hotel in Mission District can vary based on when you want to travel and how long you plan to stay, among other factors. Use our price per night filter and other search tools to land the best rate on a luxurious getaway.

  • Search for the lowest price per night from ฿5,768

What makes a hotel 5 stars in Mission District?
Exceptional guest service characterises every 5-star hotel in Mission District. From the moment you arrive, staff cater to your every need, whether answering room service calls 24/7 or providing in-room massage treatments. Also, hotels have to offer upscale amenities to be entitled to a 5-star rating. These can include luxury bathrobes, spa facilities, pools, fine dining restaurants and knowledgeable concierge.