฿6,805 Cheap Flights from Des Moines (DSM) to San Diego (SAN)

View ฿6,805 flight on Thu, 29 Jan 2026Opens in a new window

Popular airlines from Des Moines International Airport (DSM) to San Diego Intl. Airport (SAN)

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Cheap Flights from Des Moines (DSM) to San Diego (SAN)

Prices were available within the past 7 days and start at ฿6,805 for one-way flights and ฿13,605 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Thu, 29 Jan - Thu, 5 Feb
DSM
Des Moines
SAN
San Diego
฿13,605 Return, found 4 days ago
฿13,605
Return
found 4 days ago
Select Delta flight, departing Thu, 29 Jan from Des Moines to San Diego, returning Thu, 5 Feb, priced at ฿13,605 found 4 days ago
Delta
Thu, 29 Jan - Thu, 5 Feb
DSM
Des Moines
SAN
San Diego
฿14,880 Return, found 4 days ago
฿14,880
Return
found 4 days ago
Select Delta flight, departing Thu, 29 Jan from Des Moines to San Diego, returning Thu, 5 Feb, priced at ฿14,880 found 4 days ago
American Airlines
Thu, 29 Jan - Thu, 5 Feb
DSM
Des Moines
SAN
San Diego
฿15,025 Return, found 4 days ago
฿15,025
Return
found 4 days ago
Select American Airlines flight, departing Thu, 29 Jan from Des Moines to San Diego, returning Thu, 5 Feb, priced at ฿15,025 found 4 days ago
United
Thu, 29 Jan - Thu, 5 Feb
DSM
Des Moines
SAN
San Diego
฿15,050 Return, found 4 days ago
฿15,050
Return
found 4 days ago
Select United flight, departing Thu, 29 Jan from Des Moines to San Diego, returning Thu, 5 Feb, priced at ฿15,050 found 4 days ago
Delta
Thu, 29 Jan - Thu, 5 Feb
DSM
Des Moines
SAN
San Diego
฿15,065 Return, found 4 days ago
฿15,065
Return
found 4 days ago
Select Delta flight, departing Thu, 29 Jan from Des Moines to San Diego, returning Thu, 5 Feb, priced at ฿15,065 found 4 days ago
United
Thu, 29 Jan - Thu, 5 Feb
DSM
Des Moines
SAN
San Diego
฿15,445 Return, found 4 days ago
฿15,445
Return
found 4 days ago
Select United flight, departing Thu, 29 Jan from Des Moines to San Diego, returning Thu, 5 Feb, priced at ฿15,445 found 4 days ago
American Airlines
Thu, 29 Jan - Thu, 5 Feb
DSM
Des Moines
SAN
San Diego
฿16,115 Return, found 4 days ago
฿16,115
Return
found 4 days ago
Select American Airlines flight, departing Thu, 29 Jan from Des Moines to San Diego, returning Thu, 5 Feb, priced at ฿16,115 found 4 days ago
United
Thu, 29 Jan - Thu, 5 Feb
DSM
Des Moines
SAN
San Diego
฿16,145 Return, found 4 days ago
฿16,145
Return
found 4 days ago
Select United flight, departing Thu, 29 Jan from Des Moines to San Diego, returning Thu, 5 Feb, priced at ฿16,145 found 4 days ago
Delta
Thu, 29 Jan - Thu, 5 Feb
DSM
Des Moines
SAN
San Diego
฿16,150 Return, found 4 days ago
฿16,150
Return
found 4 days ago
Select Delta flight, departing Thu, 29 Jan from Des Moines to San Diego, returning Thu, 5 Feb, priced at ฿16,150 found 4 days ago
Delta
Thu, 29 Jan - Thu, 5 Feb
DSM
Des Moines
SAN
San Diego
฿16,155 Return, found 4 days ago
฿16,155
Return
found 4 days ago
Select Delta flight, departing Thu, 29 Jan from Des Moines to San Diego, returning Thu, 5 Feb, priced at ฿16,155 found 4 days ago

Find the cheapest month to fly from Des Moines (DSM) to San Diego (SAN)

April is typically the cheapest month to fly

From ฿5,123 - ฿16,215 per traveller.
Flight from Des Moines to San Diego route information
Origin airport
Des Moines Intl.
Destination airport
San Diego Intl.
Return price
฿13,605
Distance
2282 km

Perfect flights from Des Moines to San Diego

Embark on an unforgettable journey without breaking the bank with Expedia's incredible deals on cheap flights from Des Moines to San Diego. Whether you're aching for a romantic escape with your partner, craving an adventurous solo expedition, or yearning to immerse yourself in the local history and culture, we've got you covered.
 
Picture yourself strolling through the streets of , surrounded by breathtaking architecture and absorbing the vibrant atmosphere of this captivating city. Indulge in the mouth-watering local specialties, from tantalizing street food to exquisite fine dining. With Expedia, you can experience all of this and more, without sacrificing your budget.
 
Our flexible Des Moines Intl. to San Diego Intl. ticket options cater to your travel preferences, with incredible one-way fares from ฿6,805 and roundtrip prices from ฿13,605. Whether you're planning a short city break or a longer adventure, our dynamic pricing ensures that you find the best deals for your journey.
 
But the magic doesn't stop there. Expedia offers a range of partner services to enhance your trip. Rent a car at San Diego Intl. and explore and its surrounding areas at your own pace. Discover hidden gems off the beaten path, and create unforgettable memories. We also provide a handpicked selection of accommodations, from charming bed and breakfasts to luxury hotels, ensuring that you have a comfortable and memorable stay.
 
Planning your next great adventure is a breeze with Expedia. Our user-friendly platform, unbeatable prices, and round-the-clock customer support are designed to make your travel experience seamless and stress-free. So, why wait? Book your to travel arrangements today and embark on the journey of a lifetime in San Diego.

Frequently asked questions

How much is a flight from DSM to SAN?
Within the past 7 days on Expedia, for flights departing within the next year, the lowest price listed for a round-trip journey between Des Moines Intl. Airport (DSM) and San Diego Intl. Airport (SAN) was ฿13,605. Fares this cheap don't last long, so make sure you book yours ASAP. Prices and availability are subject to change. Additional terms apply.
Do I need to pay a cancellation fee if I cancel my flight from Des Moines Intl. Airport to San Diego Airport?
This can vary from airline to airline, as each one has its own set of terms and conditions. Visit the Customer Service Portal, where you'll find simple instructions on how to cancel online.
How do I find cheap flights from Des Moines Intl. Airport to San Diego Intl. Airport (SAN) that have flexible change policies?
Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for Des Moines Intl. Airport (DSM) to San Diego Intl. Airport (SAN) flights, you'll see a "no change fees" filter for you to select.
How far is the flight from DSM to San Diego Airport?
You'll be cruising at altitude for a while, as the flight distance from Des Moines to San Diego is 2,300 kilometres. Put together a playlist of your favourite songs before you leave home to keep yourself entertained during your journey.
Which airlines fly direct from Des Moines Intl. Airport (DSM) to San Diego Airport?
Operating 8 flights each month, Allegiant Air (G4) is a top choice when flying directly from DSM to San Diego Airport.
Are DSM to SAN flight tickets cheaper when they're purchased at the last minute?
Booking your trip from Des Moines Intl. Airport to San Diego Airport at the last minute could be your ticket to a great deal. However, it might cost you a whole lot more! If you'd prefer not to take the risk, book well ahead of your departure date. In fact, Expedia has some of the best bargains as far ahead as 12 months in advance. If your preferred air carrier hasn't released tickets yet, check back frequently as deals are updated all the time on Expedia.
*Available to Expedia members.