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Check prices for these dates

This weekend
23 Oct - 25 Oct
Next weekend
30 Oct - 1 Nov

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Our top choices for Uptown Greenville hotels

A modern hotel with a stone facade, large windows, and a well-lit entrance.

1. Hilton Garden INN Greenville University

Hilton Garden INN Greenville University
3.0 star property
Uptown Greenville
9.4 out of 10, Exceptional, (176 reviews)
"Really nice and new hotel."
United States
Sharon
The price is ฿5,230
฿5,910 total
includes taxes & fees
1 Nov - 2 Nov
Hilton Garden INN Greenville University
A modern hotel room with a large bed, a desk with a chair, a flat-screen TV mounted on the wall, and a wardrobe.

2. Holiday Inn Express Greenville by IHG

Holiday Inn Express Greenville by IHG
2.5 star property
2.3 km from Uptown Greenville
8.4 out of 10, Very good, (1,001 reviews)
"The room was a nice roomy size & attractive. Breakfast was pretty good & a pleasant area also."
United States
charles
The price is ฿3,478
฿3,930 total
includes taxes & fees
23 Nov - 24 Nov
Holiday Inn Express Greenville by IHG
An indoor swimming pool with clear markings, a "NO DIVING" sign, and a view of parked cars outside.

3. Fairfield Inn & Suites by Marriott Greenville

Fairfield Inn & Suites by Marriott Greenville
3.0 star property
2.4 km from Uptown Greenville
8.6 out of 10, Excellent, (515 reviews)
"The property was very nice and clean. The staff was very helpful. The shower water was nice and hot. I did experience a drainage problem in the sink. Overall, the stay was nice and comfortable."
United States
Lakisa
The price is ฿4,524
฿5,113 total
includes taxes & fees
25 Oct - 26 Oct
Fairfield Inn & Suites by Marriott Greenville
A circular fire pit with seating around it, a covered patio area, and a brick building in the background.

4. Homewood Suites By Hilton Greenville, NC

Homewood Suites By Hilton Greenville, NC
3.0 star property
2.4 km from Uptown Greenville
9.2 out of 10, Wonderful, (446 reviews)
"We love the amazing staff and this well maintained location!"
United States
Joy
The price is ฿3,851
฿4,352 total
includes taxes & fees
1 Nov - 2 Nov
Homewood Suites By Hilton Greenville, NC
An outdoor patio area with a fire pit, seating, and umbrellas.

5. Residence Inn by Marriott Greenville

Residence Inn by Marriott Greenville
3.0 star property
2.4 km from Uptown Greenville
8.8 out of 10, Excellent, (542 reviews)
"Great time"
United States
Jayvon
The price is ฿4,286
฿4,843 total
includes taxes & fees
1 Nov - 2 Nov
Residence Inn by Marriott Greenville
A spacious lobby with a stone fireplace, comfortable seating, and a bar area.

6. Staybridge Suites Greenville Medical Center by IHG

Staybridge Suites Greenville Medical Center by IHG
3.0 star property
2.3 km from Uptown Greenville
9.2 out of 10, Wonderful, (387 reviews)
"Brand new, very clean, big rooms! Would definitely stay again!"
United States
Tamara
The price is ฿4,083
฿4,614 total
includes taxes & fees
1 Nov - 2 Nov
Staybridge Suites Greenville Medical Center by IHG
A Courtyard by Marriott hotel with a covered entrance, outdoor seating, and a landscaped area.

7. Courtyard Marriott Greenville

Courtyard Marriott Greenville
3.0 star property
Medical District, 2.8 km from Uptown Greenville
8.8 out of 10, Excellent, (948 reviews)
"The rooms were clean, and the staff was outstanding. I enjoyed my stay and will visit again."
United States
Wanda
The price is ฿3,987
฿4,505 total
includes taxes & fees
1 Nov - 2 Nov
Courtyard Marriott Greenville
A modern dining area with a large window, a chandelier, and a patterned sofa.

8. Quality Inn Greenville near University

Quality Inn Greenville near University
2.5 star property
2 km from Uptown Greenville
7.4 out of 10, Good, (1,002 reviews)
"Execelente"
United States
Gerson
The price is ฿2,411
฿2,724 total
includes taxes & fees
15 Nov - 16 Nov
Quality Inn Greenville near University
An indoor swimming pool with clear windows, a lifeguard sign, and a pool depth marker.

9. Hampton Inn Greenville

Hampton Inn Greenville
2.5 star property
Convention District, 4.3 km from Uptown Greenville
9.0 out of 10, Wonderful, (684 reviews)
"This is a great property. I use it on repeat for business trips."
United States
tina
The price is ฿4,353
฿4,919 total
includes taxes & fees
25 Oct - 26 Oct
Hampton Inn Greenville
A hotel room with a desk, two beds, a sofa, a TV, and a coffee machine.

10. Best Western Plus Suites-Greenville

Best Western Plus Suites-Greenville
2.5 star property
3.9 km from Uptown Greenville
9.0 out of 10, Wonderful, (1,002 reviews)
"Had a great stay of 4 days"
United States
Thomas
The price is ฿3,860
฿4,362 total
includes taxes & fees
1 Nov - 2 Nov
Best Western Plus Suites-Greenville
A hotel entrance with a prominent 'Super 8' sign, brick facade, and potted plants.

11. Super 8 by Wyndham Greenville

Super 8 by Wyndham Greenville
2.0 star property
2.3 km from Uptown Greenville
6.6 out of 10, (616 reviews)
"Great location and friendly staff"
United States
Sharlene
The price is ฿2,209
฿2,496 total
includes taxes & fees
8 Nov - 9 Nov
Super 8 by Wyndham Greenville
A modern dining area with a long table, four chairs, and a wall-mounted television.

12. Holiday Inn Greenville by IHG

Holiday Inn Greenville by IHG
3.0 star property
Convention District, 4.3 km from Uptown Greenville
8.8 out of 10, Excellent, (1,001 reviews)
"Great place, comfortable rooms"
United States
Jonathan
The price is ฿2,904
฿3,281 total
includes taxes & fees
23 Nov - 24 Nov
Holiday Inn Greenville by IHG
A spacious lobby with a blue sofa, yellow armchairs, a central coffee table, and a wooden balcony railing.

13. Comfort Inn & Suites Greenville Near East Carolina University

Comfort Inn & Suites Greenville Near East Carolina University
2.5 star property
4.9 km from Uptown Greenville
8.8 out of 10, Excellent, (559 reviews)
"It was a decent stay!"
United States
Thomelane
The price is ฿3,727
฿4,212 total
includes taxes & fees
1 Nov - 2 Nov
Comfort Inn & Suites Greenville Near East Carolina University
A hotel room with two beds, each with patterned bedding, a bedside table with a lamp, and a framed picture on the wall.

14. Motel 6 Greenville, NC – ECU-Medical Center

Motel 6 Greenville, NC – ECU-Medical Center
2.0 star property
2.2 km from Uptown Greenville
6.4 out of 10, (136 reviews)
"Immediately walking to the room, a roach was on the wall, a roach in the refrigerators and the bathroom was next t that clean and presentable. It was a last minute booking abs a game in the area so most hotels were already sold out. I won’t book there again."
United States
Tomeka
The price is ฿2,463
฿2,783 total
includes taxes & fees
27 Oct - 28 Oct
Motel 6 Greenville, NC – ECU-Medical Center
A spacious lobby with a high ceiling, a large window, a ceiling fan, a brown leather sofa, a glass coffee table with flowers, a patterned rug, and a red carpet.

15. Econo Lodge Greenville near University

Econo Lodge Greenville near University
2.0 star property
2.3 km from Uptown Greenville
7.2 out of 10, Good, (478 reviews)
"Nice place, is great for a whole family, close to beaches."
United States
Gerardo
The price is ฿2,565
฿2,899 total
includes taxes & fees
25 Oct - 26 Oct
Econo Lodge Greenville near University
An outdoor patio with seating, a fire pit, and string lights.

16. Hilton Greenville

Hilton Greenville
4.0 star property
Convention District, 4.5 km from Uptown Greenville
8.8 out of 10, Excellent, (582 reviews)
"Best hotel in Greenville when you can’t get the place downtown!"
United States
Sara
The price is ฿5,230
฿5,910 total
includes taxes & fees
1 Nov - 2 Nov
Hilton Greenville
A hotel entrance with a sign reading 'Candlewood Suites.' There are potted plants and a mailbox in the foreground.

17. Candlewood Suites Greenville NC by IHG

Candlewood Suites Greenville NC by IHG
2.5 star property
4.7 km from Uptown Greenville
8.4 out of 10, Very good, (679 reviews)
"Room was very clean, staff was super friendly and helpful. 10/10 would stay here again."
United States
Gabriel
The price is ฿2,970
฿3,356 total
includes taxes & fees
1 Nov - 2 Nov
Candlewood Suites Greenville NC by IHG
A hotel room with two beds, a red armchair, a sofa, and a desk.

18. Country Inn & Suites by Radisson, Greenville, NC

Country Inn & Suites by Radisson, Greenville, NC
3.0 star property
6.7 km from Uptown Greenville
7.6 out of 10, Good, (937 reviews)
"The check-in was fast and the staff was very welcoming. The room was as listed and expected.; clean and well stocked with plenty of fresh towels. The breakfast staff was accommodating and very friendly;; asking would you like me to make you a waffle, now thats a first. Overall, my stay was very nice tried to book for the following weekend but they were fully booked."
United States
Letitia
The price is ฿2,976
฿3,376 total
includes taxes & fees
15 Nov - 16 Nov
Country Inn & Suites by Radisson, Greenville, NC
A clean, well-lit room with a tiled floor, a counter with a cash register, and a sign detailing room rates and policies.

19. Economy Inn of Greenville, NC

Economy Inn of Greenville, NC
2.5 star property
2.1 km from Uptown Greenville
4.4 out of 10, (119 reviews)
"I GOT NONE SMOKING ROOM.. SMELL BAD SO I WANTED MY MONEY HE SAID NO REFUND. COME FIND ITS DRUG MOTEL I WILL DO EVERYTHING N MY POWER GET THAT MOTEL CLOSE DOWN PLACE NEED BE BULL DOZIER OVER"
United States
Walter
The price is ฿1,695
฿1,915 total
includes taxes & fees
19 Nov - 20 Nov
Economy Inn of Greenville, NC
A compact living space with a kitchenette, a dining area, and a seating area with a sofa and a coffee table.

20. Affordable Suites Greenville

Affordable Suites Greenville
2.0 star property
3.8 km from Uptown Greenville
8.4 out of 10, Very good, (685 reviews)
"Not bad, no frills. A cheaper option near the university"
United States
John
The price is ฿2,369
฿2,677 total
includes taxes & fees
2 Nov - 3 Nov
Affordable Suites Greenville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Uptown Greenville

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A modern hotel with a stone facade, large windows, and a well-lit entrance.
Hilton Garden INN Greenville University
3.0 star property
9.4
Exceptional
176 reviews
View
A circular fire pit with seating around it, a covered patio area, and a brick building in the background.
Homewood Suites By Hilton Greenville, NC
3.0 star property
9.2
Wonderful
446 reviews
View
A modern hotel room with a large bed, a desk with a chair, a flat-screen TV mounted on the wall, and a wardrobe.
Holiday Inn Express Greenville by IHG
2.5 star property
8.4
Very good
1,001 reviews
View
An indoor swimming pool with clear markings, a "NO DIVING" sign, and a view of parked cars outside.
Fairfield Inn & Suites by Marriott Greenville
3.0 star property
8.6
Excellent
515 reviews
View
A spacious lobby with a stone fireplace, comfortable seating, and a bar area.
Staybridge Suites Greenville Medical Center by IHG
3.0 star property
9.2
Wonderful
387 reviews
View

Where to stay in Uptown Greenville

Find the best Uptown Greenville areas for the activities you enjoy most.

University District

While University District isn't home to many top sights, Dowdy–Ficklen Stadium and Williams Arena at Minges Coliseum are some notable places to visit nearby.

Convention District

When in Convention District, you can plan a visit to University Commons and 11 Galleria, some noteworthy sights in the nearby area.

Medical District

If you're looking for some top things to see and do in Medical District and surrounding area, you can visit Arlington Crossing and South Greenville Park.

Westhaven

Westhaven might not have many top sights, but 11 Galleria and University Commons are two attractions nearby that you can check out.

Greenville Heights

If you're looking for some top things to see and do in Greenville Heights and surrounding area, you can visit Williams Arena at Minges Coliseum and Dowdy–Ficklen Stadium.

Top Uptown Greenville Hotel Reviews

Comfort Inn & Suites Greenville Near East Carolina University

Comfort Inn & Suites Greenville Near East Carolina University

8/10 Good
"It was a decent stay!"
Thomelane 1-night trip
Posted 1 day ago
Comfort Inn & Suites Greenville Near East Carolina University

Frequently asked questions

What is Uptown Greenville like?
Travellers will be sure to find plenty to entertain them in Greenville's Uptown Greenville neighbourhood. Are you looking for Uptown Greenville travel tips? Make sure that you visit Greenville Museum of Art and Town Common while you're in the neighbourhood.
What's a favourite place to stay in Uptown Greenville?
Based on our traveller data, Hilton Garden INN Greenville University is one of the top choices for your stay in Uptown Greenville. This hotel is a short 3-minute walk from East Carolina University, and it offers a restaurant and a 24-hour fitness centre.
If I need to cancel my hotel reservation in Uptown Greenville, will I receive a refund?
Yes, the majority of hotel room reservations are refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then use the "fully refundable" filter to view top deals in Uptown Greenville.
What is there to do around this Greenville neighbourhood?
A few attractions you might want to check out while you're in Uptown Greenville are Greenville Museum of Art and Town Common. Shepherd Memorial Library - Carver Branch and North Pines are also worth a visit when you're out sightseeing in Greenville.