Southhampton Packages (Flight + Hotel)

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  • Better together

    Save up to ฿4,531 when you book a flight and hotel together*

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Where to stay in Southhampton

Find the best Southhampton areas and neighborhoods for the activities you enjoy most. Learn more about Southhampton
Meeting of the Waters Fountain showing a statue or sculpture and a fountain

Downtown St. Louis

4 out of top 10 points of interest in this area

Gourmet restaurants beloved sports teams and top sights from Busch Stadium to Gateway Arch National Park – discover Downtown St. Louis, a destination also famous for its historic sites.

Find hotels in Downtown St. Louis

Top hotels in Southhampton

Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
Fully refundableReserve now, pay when you stay
The price is ฿3,423 per night from 5 Apr to 6 Apr
฿3,423
฿4,002 total
5 Apr - 6 Apr
includes taxes & fees
8.8/10 Excellent! (1,871 reviews)
This was a wonderful hotel to stay at while we explored the National Parks. We enjoyed the free evening snacks and drinks after a full day at Gateway Arch. Staff were very friendly. The pool was nice. Rooms very clean. Would definitely stop here again.

Reviewed on 14 Mar 2026

Pear Tree Inn St. Louis Near Union Station
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
The price is ฿3,208 per night from 22 Mar to 23 Mar
฿3,208
฿3,745 total
22 Mar - 23 Mar
includes taxes & fees
8.8/10 Excellent! (3,120 reviews)
Room was nice. Bathroom was great in the suite we had. I think the best part was the breakfast. Made to order omelets and waffles. We stayed here to see Zack Bryan in concert. It was a drive to the Americas Dome but we liked this hotel. We will be staying here anytime we come to St. Louis.

Reviewed on 15 Mar 2026

Clayton Plaza Hotel & Extended Stay
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
The price is ฿4,090 per night from 5 Apr to 6 Apr
฿4,090
฿4,943 total
5 Apr - 6 Apr
includes taxes & fees
9/10 Wonderful! (1,666 reviews)
Great lock

Reviewed on 15 Mar 2026

21C Museum Hotel St Louis
See all 1,884 properties in Southhampton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Southhampton holiday package cost?
Get ready to book, because a trip to Southhampton starts from an enticing . When you bundle your flights, hotels and more into a package, you'll walk away with the best deals.
How do I get a cheap travel package to Southhampton?
It's easy. Just bundle everything together. Hotels, rental cars and flights — combine whatever you need into a Southhampton holiday package to save a ton of cash. Score even more deals when you include extras such as sightseeing tours to your booking. But that's not the only impressive part. You have the flexibility to put together your trip your own way. We offer more than 550 partner airlines and 1,000,000 hotel options across the globe, so that everyone has an opportunity to travel and fulfil those holiday fantasies.
Where should I stay in Southhampton?
A journey to Southhampton isn't complete without stopping by St. Louis Zoo and Cathedral Basilica of St. Louis. Stay within walking distance so you can easily access these popular sights.
How far in advance should I book my Southhampton holiday?
To land rock-bottom prices, book ASAP. Airlines usually release flight tickets, along with some of the lowest fares, up to a year in advance. Hotels, car rental and experiences should also be booked early to avoid disappointment. If you were hoping for a last-minute getaway in Southhampton, there are always plenty of great deals on Expedia. Book something in today!
What does an Expedia Southhampton travel package include?
That depends entirely on you. You can choose from a range of Southhampton bundles, such as a flight, hotel and rental car. You can also book a hotel with a flight, or a flight and a rental car. Once you've made your booking, you can add on the fun stuff like tours and activities. Whatever your ideal Southhampton trip looks like, get set to save!
What should I know before booking a Southhampton travel package?
Booking all the parts of your getaway together is a great way to save. Combine car rentals, airfares and hotels into a neat little package. But your options don't end at hotels. Expedia features all kinds of properties, including holiday rentals like beach villas and city apartments. Your choices are almost endless!
Can I choose my airline with a Southhampton Expedia holiday package?
With a holiday package, you're the one in charge. Whether you're looking to fly to Southhampton in economy or business class, simply select from the available airline options. Expedia has access to more than 550 airline partners globally.
If I'm not able to travel, can I cancel my Southhampton holiday package?
Because we know life can be unpredictable, the answer is yes. For further information, check out our Customer Service Portal. But generally speaking, if you've made your booking in the last 24 hours, you may be able to cancel or change it without penalty. Your airline, hotel or car rental company may charge a fee if you made your booking a while ago.

Popular places to visit

Gateway Arch showing a city, city views and skyline

Gateway Arch

Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.

Gateway Arch
City Museum which includes a city as well as children

City Museum

This quirky children’s museum invites visitors to crawl through whales, climb into tree houses and whiz down three-story slides.

City Museum
Aerial view of University City, Missouri, USA.

Barnes Jewish Hospital

If Barnes Jewish Hospital is what brings you to town, hopefully you'll have a chance to explore more of St. Louis.

Barnes Jewish Hospital

Things to do

St. Louis: Gateway Ghouls and Hauntings Walking Tour

St. Louis Ghost Tour: Sinister Sins & Shadows

฿993
per adult
St. Louis Ghost Tour: Sinister Sins & Shadows
St. Louis: Museum of Illusions Entry Ticket

St. Louis: Museum of Illusions Entry Ticket

฿1,087
per adult
100% of travellers recommend
St. Louis: Museum of Illusions Entry Ticket
Best of St. Louis Small Group Tour w/ Arch & River Cruise

St. Louis Premium Small Group Tour With Arch & River Cruise

฿5,247
per adult
84% of travellers recommend
St. Louis Premium Small Group Tour With Arch & River Cruise
See all activities in St. Louis
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.