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2 Oct - 4 Oct
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9 Oct - 11 Oct

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Our top choices for Southhampton hotels

An indoor swimming pool with lounge chairs and a pool table, surrounded by large windows.

1. Hampton Inn & Suites St. Louis at Forest Park

Hampton Inn & Suites St. Louis at Forest Park
3.5 star property
Dogtown, 4.7 km from Southhampton
9.4 out of 10, Exceptional, (1,006 reviews)
"This was an excellent location and the front desk staff made great recommendations for places to eat and things to do."
United States
Jennifer
The price is ฿4,657
฿5,492 total
includes taxes & fees
5 Oct - 6 Oct
Hampton Inn & Suites St. Louis at Forest Park
A lobby with a reception desk, seating area, and a bicycle in the background.

2. Drury Inn & Suites St. Louis Forest Park

Drury Inn & Suites St. Louis Forest Park
3.0 star property
3.3 km from Southhampton
9.4 out of 10, Exceptional, (1,018 reviews)
"Great place to stay"
United States
Robert
The price is ฿4,974
฿5,816 total
includes taxes & fees
11 Oct - 12 Oct
Drury Inn & Suites St. Louis Forest Park
A modern hotel lobby with a reception desk, seating area, and a refreshment bar.

3. SpringHill Suites St. Louis Brentwood

SpringHill Suites St. Louis Brentwood
3.0 star property
5.9 km from Southhampton
9.0 out of 10, Wonderful, (1,004 reviews)
"It was very clean and the breakfast was good and the staff was great. I would definitely recommend this Hotel to my Family and Friends thank you."
United States
Cheryl
The price is ฿3,877
฿4,575 total
includes taxes & fees
18 Oct - 19 Oct
SpringHill Suites St. Louis Brentwood
A rooftop terrace with wicker furniture, offering a city view.

4. Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
3.0 star property
Downtown St. Louis, 9.3 km from Southhampton
9.6 out of 10, Exceptional, (3,786 reviews)
"Excellent stay"
United States
Salvatore
The price is ฿4,507
฿5,270 total
includes taxes & fees
3 Oct - 4 Oct
Drury Plaza Hotel St. Louis at the Arch
A modern outdoor lounge area with seating, a bar, and a view of a cityscape.

5. Live by Loews - St.Louis

Live by Loews - St.Louis
4.0 star property
Downtown St. Louis, 8.9 km from Southhampton
9.4 out of 10, Exceptional, (1,344 reviews)
"Great stay!"
United States
Molly
The price is ฿5,309
฿6,313 total
includes taxes & fees
4 Oct - 5 Oct
Live by Loews - St.Louis
An outdoor patio with a fire pit, seating, and a building in the background.

6. Courtyard by Marriott St. Louis Brentwood

Courtyard by Marriott St. Louis Brentwood
3.0 star property
6.3 km from Southhampton
9.4 out of 10, Exceptional, (904 reviews)
"Clean comfortable room and mattress."
United States
Aaron
The price is ฿3,945
฿4,811 total
includes taxes & fees
11 Oct - 12 Oct
Courtyard by Marriott St. Louis Brentwood
An outdoor seating area with a fire pit, cushioned benches, and a covered patio with string lights.

7. Home2 Suites by Hilton St. Louis/Forest Park

Home2 Suites by Hilton St. Louis/Forest Park
3.0 star property
The Grove, 5.3 km from Southhampton
8.6 out of 10, Excellent, (1,002 reviews)
"Staff was nice and helpful food was great and room was amazing!!! "
United States
paullita jeanne
The price is ฿5,225
฿6,109 total
includes taxes & fees
4 Oct - 5 Oct
Home2 Suites by Hilton St. Louis/Forest Park
A long bar with multiple tables and chairs, wooden floors, and ornate chandeliers.

8. River City Casino & Hotel

River City Casino & Hotel
4.0 star property
6.7 km from Southhampton
9.0 out of 10, Wonderful, (1,807 reviews)
"Would definitely stay here again!"
United States
Ashley
The price is ฿3,243
฿4,261 total
includes taxes & fees
15 Oct - 16 Oct
River City Casino & Hotel
A lobby with a sofa, two armchairs, a coffee table, and a staircase.

9. Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis, 9.5 km from Southhampton
8.6 out of 10, Excellent, (4,325 reviews)
"Great place to stay"
United States
David
The price is ฿4,477
฿5,280 total
includes taxes & fees
2 Oct - 3 Oct
Hyatt Regency St. Louis at The Arch
A cozy lounge area with leather sofas, a fireplace, and a bar counter.

10. The Cheshire

The Cheshire
4.0 star property
5.5 km from Southhampton
8.8 out of 10, Excellent, (1,011 reviews)
"Fantastic hotel, clean and nice rooms, great breakfast and location"
United States
Matthew
The price is ฿4,987
฿5,922 total
includes taxes & fees
18 Oct - 19 Oct
The Cheshire
A modern bar area with a wooden bar counter, black bar stools, and a large wall with city names.

11. Fairfield Inn & Suites by Marriott St. Louis Downtown

Fairfield Inn & Suites by Marriott St. Louis Downtown
3.0 star property
Downtown West, 7.9 km from Southhampton
9.2 out of 10, Wonderful, (1,002 reviews)
"Nice hotel, great staff. Directly across the street from Energizer/City Park. Parking is $25/night and well worth it."
United States
James
The price is ฿4,177
฿4,976 total
includes taxes & fees
8 Oct - 9 Oct
Fairfield Inn & Suites by Marriott St. Louis Downtown
A restaurant with round tables and chairs, a bar area, and a patterned ceiling.

12. Drury Plaza Hotel St. Louis Brentwood

Drury Plaza Hotel St. Louis Brentwood
4.0 star property
6.9 km from Southhampton
9.6 out of 10, Exceptional, (1,018 reviews)
"Excellent place to stay. Beautiful hotel, amazing friendly and attentive staff. Would highly recommend!!"
United States
Janell
The price is ฿4,540
฿5,390 total
includes taxes & fees
11 Oct - 12 Oct
Drury Plaza Hotel St. Louis Brentwood
A multi-story hotel with a prominent corner location, large windows, and a well-lit facade.

13. Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
Downtown St. Louis, 9.5 km from Southhampton
9.0 out of 10, Wonderful, (1,354 reviews)
"Beautiful place to stay"
United States
Karen
The price is ฿3,805
฿4,526 total
includes taxes & fees
11 Oct - 12 Oct
Embassy Suites by Hilton St. Louis Downtown
An outdoor dining area with a table and chairs, a neon sign, and a glass railing overlooking a cityscape.

14. Aloft by Marriott St Louis Central West End

Aloft by Marriott St Louis Central West End
3.0 star property
Central West End, 6.1 km from Southhampton
8.6 out of 10, Excellent, (1,010 reviews)
"Lovely location and amazing room"
United States
Jacob
The price is ฿3,803
฿4,447 total
includes taxes & fees
11 Oct - 12 Oct
Aloft by Marriott St Louis Central West End
A modern hotel room with a dining area, wooden cabinets, a checkered floor, and a flat-screen TV.

15. Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport
3.0 star property
18.4 km from Southhampton
9.2 out of 10, Wonderful, (1,719 reviews)
"Staff was wonderful..great location with BBQ restaurant next door"
United States
Mary
The price is ฿3,121
฿3,675 total
includes taxes & fees
12 Oct - 13 Oct
Wingate by Wyndham St. Louis Airport
A hotel room with a minibar, a shoe rack, a coat rack, and a TV.

16. Holiday Inn Express & Suites St. Louis South - I-55 by IHG

Holiday Inn Express & Suites St. Louis South - I-55 by IHG
2.5 star property
12.9 km from Southhampton
9.6 out of 10, Exceptional, (1,001 reviews)
"Room was clean staff friendly"
United States
Thomas
The price is ฿4,173
฿4,799 total
includes taxes & fees
4 Oct - 5 Oct
Holiday Inn Express & Suites St. Louis South - I-55 by IHG
The Clayton Plaza Hotel sign with a stone wall and plants in front.

17. Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay
3.5 star property
8.2 km from Southhampton
8.8 out of 10, Excellent, (3,451 reviews)
"Great place to stay."
United States
Sivakumar
The price is ฿3,088
฿3,605 total
includes taxes & fees
11 Oct - 12 Oct
Clayton Plaza Hotel & Extended Stay
A rooftop restaurant with round tables, chairs, and a view of the city.

18. Moonrise Hotel

Moonrise Hotel
4.0 star property
7.7 km from Southhampton
9.0 out of 10, Wonderful, (2,029 reviews)
"Great location, clean rooms, and friendly staff. We will definitely stay again."
United States
Nicole
The price is ฿4,407
฿5,241 total
includes taxes & fees
30 Sept - 1 Oct
Moonrise Hotel
An indoor swimming pool with a hot tub, lounge chairs, and a brick wall with artwork.

19. Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station
3.0 star property
Downtown West, 7.9 km from Southhampton
8.8 out of 10, Excellent, (2,214 reviews)
"The pool and food and rooms were nice"
United States
Michael
The price is ฿3,906
฿4,567 total
includes taxes & fees
4 Oct - 5 Oct
Pear Tree Inn St. Louis Near Union Station
A hotel room with two beds, a chair, a desk, and a large window.

20. Forest Park Hotel by MDR

Forest Park Hotel by MDR
3.0 star property
The Hill, 3.4 km from Southhampton
7.4 out of 10, Good, (1,650 reviews)
"Comfortable bed and room. Friendly staff. Convenient location."
United States
Janice
The price is ฿2,595
฿3,191 total
includes taxes & fees
28 Oct - 29 Oct
Forest Park Hotel by MDR
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Southhampton

Find the best Southhampton areas for the activities you enjoy most.
The Gateway Arch in St. Louis, Missouri, with a well-maintained lawn and trees in the foreground.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Gateway Arch National Park to Kiener Plaza – discover Downtown St. Louis, a destination also famous for its historic sites.

A gazebo by a calm pond with autumn foliage and clear skies.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

A fountain in front of a red brick building with green roofs and white trim.

Central West End

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

A wooden bridge with metal trusses, surrounded by trees.

St. Charles Historic District

St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Missouri River while in the area.

A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

Top Southhampton Hotel Reviews

Drury Plaza Hotel St. Louis Union Station

Drury Plaza Hotel St. Louis Union Station

10/10 Excellent
"You should use a lot of taxies."
spandana 2-night trip
Posted 5 hours ago
Drury Plaza Hotel St. Louis Union Station

Frequently asked questions

What is Southhampton like?
Travellers to the Southhampton neighbourhood in St. Louis will be sure to enjoy their stay.
How many hotels should I expect to find in the Southhampton area?
When you want to put your feet up after a day of exploring the sights in St. Louis, you can choose from 18 Expedia hotels and other accommodation options in Southhampton.
If I need to cancel my hotel reservation in Southhampton, will I receive a refund?
Yes! The majority of hotel bookings are refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within a 24-hour period of your booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to view the top deals on offer in Southhampton.
What can I see and do in this St. Louis neighbourhood?
A few places to visit in the area around Southhampton include The Heavy Anchor, Das Bevo and Miniature Museum of Greater St. Louis. When you're sightseeing in St. Louis, Lindenwood Park and River des Peres Greenway Trailhead are also worth a stop.