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Our top choices for Southhampton hotels

Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis
2.5 star property
27.1 km from Southhampton
8.4 out of 10, Very good, (1,003 reviews)
"Great hotel for the money"
United States
Jere
The price is ฿2,418
฿2,779 total
includes taxes & fees
25 Jan - 26 Jan
Comfort Suites St Charles - St Louis

Hampton Inn & Suites St. Charles Old Town Area

Hampton Inn & Suites St. Charles Old Town Area
2.5 star property
26.9 km from Southhampton
9.2 out of 10, Wonderful, (643 reviews)
"The breakfast was delicious and contained a wide variety. The staff friendly and the rooms very clean. "
United States
Kim
The price is ฿3,554
฿4,277 total
includes taxes & fees
8 Feb - 9 Feb
Hampton Inn & Suites St. Charles Old Town Area

Tru by Hilton St. Charles St. Louis, MO

Tru by Hilton St. Charles St. Louis, MO
2.5 star property
26.9 km from Southhampton
8.6 out of 10, Excellent, (781 reviews)
"Clean hotel, nice staff and comfortable beds."
United States
Jennifer
The price is ฿3,306
฿3,832 total
includes taxes & fees
8 Feb - 9 Feb
Tru by Hilton St. Charles St. Louis, MO

Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles
3.5 star property
27.7 km from Southhampton
8.8 out of 10, Excellent, (1,000 reviews)
"My favorite hotel"
United States
Edward
The price is ฿3,843
฿4,417 total
includes taxes & fees
1 Feb - 2 Feb
Embassy Suites by Hilton St. Louis St. Charles

Best Western Plus The Charles Hotel

Best Western Plus The Charles Hotel
3.0 star property
27.3 km from Southhampton
8.2 out of 10, Very good, (1,005 reviews)
"Very nice at service desk, room clean and comfortable, breakfast really good. Would recommend, would stay again!"
United States
Melisa
The price is ฿2,723
฿3,156 total
includes taxes & fees
21 Jan - 22 Jan
Best Western Plus The Charles Hotel

Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles
3.0 star property
26.8 km from Southhampton
9.6 out of 10, Exceptional, (1,011 reviews)
"Great hotel "
United States
John Christopher
The price is ฿3,594
฿4,166 total
includes taxes & fees
25 Jan - 26 Jan
Drury Plaza Hotel St. Louis St. Charles

Motel 6 Hazelwood, MO

Motel 6 Hazelwood, MO
2.0 star property
22.6 km from Southhampton
8.4 out of 10, Very good, (1,699 reviews)
"Great location, friendly staff, and clean rooms. Definitely will stay again"
United States
Zaylee
The price is ฿1,870
฿2,286 total
includes taxes & fees
3 Feb - 4 Feb
Motel 6 Hazelwood, MO

Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District
2.5 star property
27 km from Southhampton
9.4 out of 10, Exceptional, (1,000 reviews)
"We had a great stay in a beautiful area. The staff were friendly, and Kay at the front desk was so kind and welcoming!"
United States
Audrey
The price is ฿3,682
฿4,231 total
includes taxes & fees
25 Jan - 26 Jan
Country Inn & Suites by Radisson, St. Charles Historic District

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
26.6 km from Southhampton
8.4 out of 10, Very good, (1,012 reviews)
"Was an amazing hotel to stay at!! Clean spacious and very nice!!! Will stay here again!!"
United States
Darci
The price is ฿5,597
฿7,061 total
includes taxes & fees
25 Jan - 26 Jan
Ameristar Casino Resort and Spa

Best Western St. Louis-Kirkwood Route 66

Best Western St. Louis-Kirkwood Route 66
3.5 star property
10.9 km from Southhampton
8.4 out of 10, Very good, (1,397 reviews)
"Room, breakfast and location are all good. We stayed here three days for hidden valley ski, I don't regret the choice:)"
United States
Xiongyu
The price is ฿2,939
฿3,438 total
includes taxes & fees
25 Jan - 26 Jan
Best Western St. Louis-Kirkwood Route 66

Fairfield Inn & Suites by Marriott St. Louis South

Fairfield Inn & Suites by Marriott St. Louis South
2.5 star property
13.1 km from Southhampton
9.6 out of 10, Exceptional, (331 reviews)
"The room was good."
United States
Steve
The price is ฿3,628
฿4,172 total
includes taxes & fees
8 Feb - 9 Feb
Fairfield Inn & Suites by Marriott St. Louis South

Missouri Athletic Club

Missouri Athletic Club
3.5 star property
Downtown St. Louis, 9.7 km from Southhampton
8.8 out of 10, Excellent, (1,002 reviews)
"The room was nice and the staff was excellent."
United States
Annette
The price is ฿5,438
฿6,359 total
includes taxes & fees
21 Jan - 22 Jan
Missouri Athletic Club

Courtyard by Marriott St. Louis Downtown/Convention Center

Courtyard by Marriott St. Louis Downtown/Convention Center
3.0 star property
Downtown St. Louis, 9.4 km from Southhampton
9.0 out of 10, Wonderful, (1,003 reviews)
"Very clean rooms and very friendly, helpful staff "
United States
Emily
The price is ฿3,028
฿3,602 total
includes taxes & fees
9 Feb - 10 Feb
Courtyard by Marriott St. Louis Downtown/Convention Center

Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
Downtown St. Louis, 9.5 km from Southhampton
8.8 out of 10, Excellent, (1,283 reviews)
"Great stay and staff "
United States
Mykeshia
The price is ฿3,434
฿4,084 total
includes taxes & fees
27 Jan - 28 Jan
Embassy Suites by Hilton St. Louis Downtown

Hyatt Select St. Louis Airport

Hyatt Select St. Louis Airport
2.5 star property
17.5 km from Southhampton
9.2 out of 10, Wonderful, (1,003 reviews)
"Great hotel"
United States
Leon
The price is ฿3,628
฿4,455 total
includes taxes & fees
27 Jan - 28 Jan
Hyatt Select St. Louis Airport

Courtyard by Marriott St Louis Creve Coeur

Courtyard by Marriott St Louis Creve Coeur
3.0 star property
Creve Coeur, 16.7 km from Southhampton
8.8 out of 10, Excellent, (1,000 reviews)
"Clean room and very helpful staff"
United States
Amy
The price is ฿3,563
฿4,141 total
includes taxes & fees
30 Jan - 31 Jan
Courtyard by Marriott St Louis Creve Coeur

Home2 Suites by Hilton St. Louis Downtown

Home2 Suites by Hilton St. Louis Downtown
3.0 star property
Downtown West, 9 km from Southhampton
8.0 out of 10, Very good, (655 reviews)
"Great stay "
United States
Kevin
The price is ฿2,435
฿2,847 total
includes taxes & fees
2 Feb - 3 Feb
Home2 Suites by Hilton St. Louis Downtown

Comfort Inn & Suites Saint Louis Lafayette Square

Comfort Inn & Suites Saint Louis Lafayette Square
2.5 star property
The Gate, 6.3 km from Southhampton
8.0 out of 10, Very good, (274 reviews)
"Very clean and quiet"
United States
Adrienne
The price is ฿2,975
฿3,479 total
includes taxes & fees
30 Jan - 31 Jan
Comfort Inn & Suites Saint Louis Lafayette Square

Red Lion Inn & Suites Pontoon Beach

Red Lion Inn & Suites Pontoon Beach
2.5 star property
26.9 km from Southhampton
7.8 out of 10, Good, (600 reviews)
"There was a good toilet in the room very clean and nice "
United States
John
The price is ฿1,840
฿2,083 total
includes taxes & fees
21 Jan - 22 Jan
Red Lion Inn & Suites Pontoon Beach

Drury Inn & Suites St. Louis Union Station

Drury Inn & Suites St. Louis Union Station
3.0 star property
Downtown West, 7.9 km from Southhampton
9.4 out of 10, Exceptional, (1,336 reviews)
"Amazing hotel and staff!! "
United States
Alexandra
The price is ฿3,719
฿4,423 total
includes taxes & fees
25 Jan - 26 Jan
Drury Inn & Suites St. Louis Union Station
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Southhampton

Find the best Southhampton areas for the activities you enjoy most.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Busch Stadium – discover Downtown St. Louis, a destination also famous for its historic sites.

Berkeley

Visitors highly recommend Berkeley for its abundant dining options, and you can make a stop by James S. McDonnell Prologue Room while you're in town.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

Central West End

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

Downtown West

While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and St. Louis Aquarium at Union Station.

Top Southhampton Hotel Reviews

Frequently asked questions

What is Southhampton like?
Travellers to the Southhampton neighbourhood in St. Louis will be sure to enjoy their stay.
How many hotels should I expect to find in the Southhampton area?
If you're searching for places to stay in St. Louis, Expedia has something to meet your needs with 22 Southhampton hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in Southhampton, will I receive a refund?
Yes! The majority of hotel bookings are refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within a 24-hour period of your booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to view the top deals on offer in Southhampton.
What can I see and do in this St. Louis neighbourhood?
A few places to visit in the area around Southhampton include Miniature Museum of Greater St. Louis, Lindenwood Park and River des Peres Greenway Trailhead. When you're sightseeing in St. Louis, Tower Grove Tennis Center and George Washington Carver Garden are also worth a stop.