Search Hotels in Southampton, Houston

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Southampton hotels

Studio 6 Houston, TX – Pearland/Medical Center

Studio 6 Houston, TX – Pearland/Medical Center
2.0 star property
Southeast Houston, 16.4 km from Southampton
9.6 out of 10, Exceptional, (51 reviews)
"Wonderful stay and well worth the price."
United States
Francis
The price is ฿2,150
฿2,515 total
includes taxes & fees
11 May - 12 May
Studio 6 Houston, TX – Pearland/Medical Center

Palace Inn Blue 290 W 43rd & Bingle Rd

Palace Inn Blue 290 W 43rd & Bingle Rd
2.5 star property
14.7 km from Southampton
9.4 out of 10, Exceptional, (46 reviews)
"Very nice clean quiet property close to many restaurants."
United States
Hilary and Cynthia
The price is ฿3,031
฿3,546 total
includes taxes & fees
3 May - 4 May
Palace Inn Blue 290 W 43rd & Bingle Rd

Hotel Royale

Hotel Royale
2.0 star property
22.9 km from Southampton
9.2 out of 10, Wonderful, (31 reviews)
"Room was very clean and convenient for my short stay. Would recommend for business trips. "
United States
Jerome
The price is ฿2,623
฿3,069 total
includes taxes & fees
16 May - 17 May
Hotel Royale

Palace Inn Blue Edgebrook

Palace Inn Blue Edgebrook
3.0 star property
17.9 km from Southampton
9.4 out of 10, Exceptional, (166 reviews)
"Nice place to stay"
United States
Bella
The price is ฿2,963
฿3,571 total
includes taxes & fees
3 May - 4 May
Palace Inn Blue Edgebrook

Best Western Plus Pearland/Houston Medical Center Hotel

Best Western Plus Pearland/Houston Medical Center Hotel
2.5 star property
Southeast Houston, 14.6 km from Southampton
9.4 out of 10, Exceptional, (233 reviews)
"Simply amazing stay "
United States
Jesus
The price is ฿2,897
฿3,390 total
includes taxes & fees
20 May - 21 May
Best Western Plus Pearland/Houston Medical Center Hotel

Kompose Residences Houston Cy-Fair

Kompose Residences Houston Cy-Fair
3.0 star property
29.7 km from Southampton
9.4 out of 10, Exceptional, (459 reviews)
"Great breakfast!"
United States
Mariah
The price is ฿2,187
฿2,963 total
includes taxes & fees
3 May - 4 May
Kompose Residences Houston Cy-Fair

Best Western Plus Manvel Inn & Suites

Best Western Plus Manvel Inn & Suites
2.5 star property
27.9 km from Southampton
8.8 out of 10, Excellent, (781 reviews)
"Everything about this place was awesome. Will definitely be staying there again on my next trip!!!!!"
United States
Penny
The price is ฿2,587
฿2,924 total
includes taxes & fees
31 May - 1 Jun
Best Western Plus Manvel Inn & Suites

Courtyard by Marriott Houston Intercontinental Airport

Courtyard by Marriott Houston Intercontinental Airport
3.0 star property
26.4 km from Southampton
9.0 out of 10, Wonderful, (1,203 reviews)
"Wonderful place to stay!"
United States
Lisa
The price is ฿4,118
฿4,818 total
includes taxes & fees
9 May - 10 May
Courtyard by Marriott Houston Intercontinental Airport

La Quinta Inn & Suites by Wyndham Houston Bush IAH South

La Quinta Inn & Suites by Wyndham Houston Bush IAH South
3.0 star property
25.7 km from Southampton
8.2 out of 10, Very good, (1,909 reviews)
"Breakfast was good, love everything about this place."
United States
John
The price is ฿2,798
฿3,273 total
includes taxes & fees
3 May - 4 May
La Quinta Inn & Suites by Wyndham Houston Bush IAH South

SpringHill Suites by Marriott Houston Intercontinental Arprt

SpringHill Suites by Marriott Houston Intercontinental Arprt
3.0 star property
26.4 km from Southampton
9.0 out of 10, Wonderful, (1,733 reviews)
"wonderful stay "
United States
Stepfan
The price is ฿3,289
฿3,848 total
includes taxes & fees
15 May - 16 May
SpringHill Suites by Marriott Houston Intercontinental Arprt

SureStay Plus Hotel by Best Western Humble

SureStay Plus Hotel by Best Western Humble
2.5 star property
27.4 km from Southampton
9.0 out of 10, Wonderful, (632 reviews)
"Great location, would stay again."
United States
David
The price is ฿2,194
฿2,568 total
includes taxes & fees
13 May - 14 May
SureStay Plus Hotel by Best Western Humble

Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center
4.5 star property
Texas Medical Center, 1.5 km from Southampton
8.4 out of 10, Very good, (1,895 reviews)
"Excellent stay while there for a tournament near NRG. Perfect location. The staff was so wonderful! "
United States
Lindsy
The price is ฿3,550
฿4,191 total
includes taxes & fees
24 May - 25 May
Hilton Houston Plaza/Medical Center

Crystal Inn - NorthWest - 290

Crystal Inn - NorthWest - 290
2.0 star property
20.6 km from Southampton
9.8 out of 10, Exceptional, (52 reviews)
"Everything was great will stay again if in the area "
United States
Curtis
The price is ฿3,485
฿4,007 total
includes taxes & fees
4 May - 5 May
Crystal Inn - NorthWest - 290

Spark by Hilton Houston Bush Intercontinental Airport

Spark by Hilton Houston Bush Intercontinental Airport
3.0 star property
25.7 km from Southampton
8.6 out of 10, Excellent, (1,001 reviews)
"Great option close to the airport! "
United States
Lisa
The price is ฿2,807
฿3,284 total
includes taxes & fees
26 May - 27 May
Spark by Hilton Houston Bush Intercontinental Airport

Palace Inn Blue Houston East Beltway 8

Palace Inn Blue Houston East Beltway 8
2.5 star property
Northeast Houston, 26.1 km from Southampton
9.0 out of 10, Wonderful, (397 reviews)
"The room was very nice and clean. Wheelchair accessible and handicapped friendly. "
United States
Amanda
The price is ฿2,341
฿2,692 total
includes taxes & fees
3 May - 4 May
Palace Inn Blue Houston East Beltway 8

Hilton Garden Inn Houston Hobby Airport, TX

Hilton Garden Inn Houston Hobby Airport, TX
3.0 star property
16 km from Southampton
8.8 out of 10, Excellent, (1,001 reviews)
"Friendly staff, clean rooms, convenient location to airport "
United States
Elizabeth
The price is ฿2,967
฿3,471 total
includes taxes & fees
10 May - 11 May
Hilton Garden Inn Houston Hobby Airport, TX

Club Quarters Hotel Downtown, Houston

Club Quarters Hotel Downtown, Houston
4.0 star property
Houston Central Business District, 6.1 km from Southampton
8.6 out of 10, Excellent, (4,126 reviews)
"Nice stay"
United States
Chermaine
The price is ฿3,691
฿4,319 total
includes taxes & fees
21 May - 22 May
Club Quarters Hotel Downtown, Houston

Moxy Houston Downtown

Moxy Houston Downtown
3.0 star property
Downtown Houston, 6.4 km from Southampton
8.6 out of 10, Excellent, (917 reviews)
"The location was perfect for going to a baseball game."
United States
Michael
The price is ฿3,826
฿4,552 total
includes taxes & fees
10 May - 11 May
Moxy Houston Downtown

Hampton Inn & Suites Houston-Bush Intercontinental Aprt

Hampton Inn & Suites Houston-Bush Intercontinental Aprt
3.0 star property
26.3 km from Southampton
8.8 out of 10, Excellent, (1,855 reviews)
"Clean, comfy beds & friendly staff!"
United States
Andrea
The price is ฿3,123
฿3,673 total
includes taxes & fees
1 Jun - 2 Jun
Hampton Inn & Suites Houston-Bush Intercontinental Aprt

GreenTree Hotel & Extended Stay I-10 FWY Houston, Channelview, Baytown

GreenTree Hotel & Extended Stay I-10 FWY Houston, Channelview, Baytown
3.0 star property
26.4 km from Southampton
8.6 out of 10, Excellent, (686 reviews)
"Amazing staff and breakfast"
United States
Tiffany
The price is ฿1,748
฿2,011 total
includes taxes & fees
6 May - 7 May
GreenTree Hotel & Extended Stay I-10 FWY Houston, Channelview, Baytown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Southampton

Find the best Southampton areas for the activities you enjoy most.

Downtown Houston

Tour the beautiful green spaces, buzzing theater district and professional sports arenas nestled beneath a dramatic cityscape of gleaming skyscrapers.

The Galleria

Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Williams Tower.

Texas Medical Center

Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

Montrose

Unique features of Montrose include the theatres and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Downtown Transit Center Station.

Top Southampton Hotel Reviews

Frequently asked questions

What is Southampton like?
Travellers will be sure to enjoy their time in Houston's Southampton neighbourhood.
If I need to cancel my hotel reservation in Southampton, will I receive a refund?
Yes, you'll find most room reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you have a reservation that's non-refundable, you might be able to cancel it and be given a refund within 24 hours of booking. Add your dates and click on "Search", then you can filter by "fully refundable" to view top deals in Southampton.
What can I see and do in this Houston neighbourhood?
A few places to visit in the area around Southampton include NRG Stadium, James Turrell's Twilight Epiphany Skyscape and Rice Stadium. When you're sightseeing in Houston, Main Street Theater - Rice Village and Tudor Fieldhouse are also worth a stop.