Santa Cruz Travel Guide

Seville

A narrow cobblestone street lined with colorful buildings, shops, and a prominent white archway in the distance.
A historic plaza with ornate Gothic architecture, palm trees, and people walking.
A narrow street lined with trees and buildings, with people sitting at outdoor cafes.
A sunny urban square with tram tracks, historic buildings, and pedestrians.
A historic building with ornate columns, a large archway, and a statue.

Stay near popular Santa Cruz attractions

A courtyard with a central water feature, surrounded by columns and potted trees.

Royal Alcázar of Seville

9.6/10 (8,220 reviews)
Discover a millennium’s worth of royal treasures in this architectural masterpiece in the heart of Seville.
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Things to do

Skip the line combo tour to Alcazar & Cathedral of Seville

Cathedral & Alcázar of Seville Guided Tour Combo

฿1,147
per adult
88% of travellers recommend
Cathedral & Alcázar of Seville Guided Tour Combo
Landscape of Guadalquivir river area with several buildings in view.

Guadalquivir River Criuse Tour

฿722
per adult
80% of travellers recommend
Guadalquivir River Criuse Tour
Guided visit to Seville Fine Arts Museum

Fine Arts Museum of Seville Guided Tour with Tickets Included

฿688
per adult
Fine Arts Museum of Seville Guided Tour with Tickets Included
Three Cities in One Day: Córdoba, White Villages and Ronda from Sevilla

Three Cities in One Day: Córdoba, White Villages and Ronda from Sevilla

฿4,204
per adult
Three Cities in One Day: Córdoba, White Villages and Ronda from Sevilla
Sevilla, Córdoba and Andalusian Villages Discovery Guide

Sevilla, Córdoba and Andalusian Villages Discovery Guide

฿38
per adult
Sevilla, Córdoba and Andalusian Villages Discovery Guide
From Seville: Ronda and Setenil de las Bodegas Day Trip

From Seville: Discover SETENIL & RONDA

฿1,873
per adult
90% of travellers recommend
From Seville: Discover SETENIL & RONDA
See all activities in Seville

Top hotels in Santa Cruz

Las Casas de la Judería, Sevilla Historic City Center

Las Casas de la Judería, Sevilla Historic City Center

4 out of 5
Calle Santa Maria La Blanca 5 Seville Seville
The price is ฿6,053 per night from 10 Sept to 11 Sept
฿6,053
฿6,658 total
10 Sept - 11 Sept
includes taxes & fees
Stay at this spa hotel in Seville. Enjoy free Wi-Fi, an outdoor pool and a full-service spa. Our guests praise the pool and the helpful staff in their reviews. ...
9.2/10 Wonderful! (1,007 reviews)
"La beauté de l’hôtel qui ressemblait plus à une villa"

Reviewed on 3 Sept 2026

Las Casas de la Judería, Sevilla Historic City Center
Hotel Alfonso XIII, a Luxury Collection Hotel, Seville

Hotel Alfonso XIII, a Luxury Collection Hotel, Seville

5 out of 5
San Fernando 2 Seville Seville
Fully refundableReserve now, pay when you stay
The price is ฿22,700 per night from 13 Sept to 14 Sept
฿22,700
฿24,970 total
13 Sept - 14 Sept
includes taxes & fees
Stay at this luxury hotel in Seville. Enjoy 2 restaurants, breakfast (surcharge) and 24-hour room service. Our guests praise the helpful staff in their reviews. ...
Hotel Alfonso XIII, a Luxury Collection Hotel, Seville
Hotel Fernando III

Hotel Fernando III

4 out of 5
San Jose 21 Seville Seville
The price is ฿7,570 per night from 7 Sept to 8 Sept
฿7,570
฿8,327 total
7 Sept - 8 Sept
includes taxes & fees
Stay at this business-friendly hotel in Seville. Enjoy free Wi-Fi, an outdoor pool and a rooftop terrace. Our guests praise the breakfast and the pool in their ...
Hotel Fernando III
Hotel Amadeus Sevilla

Hotel Amadeus Sevilla

4 out of 5
Calle Farnesio 6 Seville Seville
The price is ฿5,761 per night from 9 Sept to 10 Sept
฿5,761
฿6,337 total
9 Sept - 10 Sept
includes taxes & fees
Stay at this boutique hotel in Seville. Enjoy free Wi-Fi, a rooftop terrace and breakfast (surcharge). Our guests praise the breakfast and the bar in their reviews. ...
9.6/10 Exceptional! (1,272 reviews)
"This lovely hotel is located very close to all of the major sites in Seville. The stuff were very helpful. I’m the room had everything we needed. What really made it special for us was our lovely terrorist area, so glad we decided to upgrade. Lead out onto the roof terrace which was a lovely place ..."

Reviewed on 6 Sept 2026

Hotel Amadeus Sevilla
Hotel Murillo

Hotel Murillo

2 out of 5
Calle Lope de Rueda, 7-9 Seville Seville
The price is ฿2,506 per night from 7 Sept to 8 Sept
฿2,506
฿2,756 total
7 Sept - 8 Sept
includes taxes & fees
Stay at this family-friendly hotel in Seville. Enjoy free Wi-Fi, a rooftop terrace and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
Hotel Murillo
Hotel Rey Alfonso X

Hotel Rey Alfonso X

4 out of 5
Calle Ximenez De Enciso, 35 Seville Seville
The price is ฿7,226 per night from 7 Sept to 8 Sept
฿7,226
฿7,948 total
7 Sept - 8 Sept
includes taxes & fees
Stay at this hotel in Seville. Enjoy free Wi-Fi, an outdoor pool and a rooftop terrace. Our guests praise the breakfast and the pool in their reviews. Popular ...
9.4/10 Exceptional! (1,220 reviews)
"Great location. Hotel is central in Seville and very walkable to many things nearby. There are many great restaurants a few steps away. We got the breakfast buffet each morning, which is accessible on the lowest level of the hotel. Lots of good food options and very friendly staff. Our room was a ..."

Reviewed on 6 Sept 2026

Hotel Rey Alfonso X
See all 417 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Cruz

Find the best Santa Cruz areas for the activities you enjoy most.
A bustling outdoor cafe with patrons seated at tables, set against a backdrop of a historic building with ornate architecture and a prominent church steeple.

Historical Center

Known for its fantastic nightlife, stunning cathedral and popular shops, there's plenty to explore in Historical Center. Top attractions like Casa de la Memoria Cultural Center and Calle Sierpes are major draws. Catch the metro at Plaza Nueva Tram Stop or Archivo de Indias Tram Stop to see more of the city.

A historic plaza with ornate buildings, including a curved structure with a statue and a tall tower with intricate architecture.

El Arenal

Travellers choose El Arenal for its abundant dining options. Hop aboard the metro at Plaza Nueva Tram Stop or Archivo de Indias Tram Stop and check out top sights like Paseo de Cristóbal Colón.

A bustling outdoor café area with people dining and walking.

Alfalfa

Unique features of Alfalfa include the bars and historical sites. Make a stop by Calle Sierpes or Casa de la Memoria Cultural Center while you're exploring the area.

A riverside promenade with a bridge, historic buildings, and a calm river.

Triana

Known for its abundant dining options and stunning river views, there's plenty to explore in Triana. Top attractions like Triana Market and Triana Bridge are major draws, and you can catch the metro at Plaza de Cuba Station or Cartuja Station to see more of the city.

A large fountain with water jets in front of a historic building with a clock tower.
Photo by Aram Farshyan
Open Photo by Aram Farshyan

San Bartolomé

Travellers come to San Bartolomé for its lively bars, and you can see top attractions like Pilate's House and Zurbarán Statue while you're in town.

Santa Cruz Travel Guide