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Check prices for these dates

Tonight
6 Nov - 7 Nov
Tomorrow
7 Nov - 8 Nov
This weekend
6 Nov - 8 Nov
Next weekend
13 Nov - 15 Nov

Our top choices for Santa Maria Novella LGBT-friendly hotels

A reception area with a marble counter, a large mirror, and two potted plants.

1. Hotel Boccaccio

Hotel Boccaccio
3.5 star property
Historic Centre of Florence
9.2 out of 10, Wonderful, (1,021 reviews)
"Great location, great staff,"
United Kingdom
robert
The price is ฿2,733
฿3,460 total
includes taxes & fees
8 Nov - 9 Nov
Hotel Boccaccio
A hotel entrance with a double door, a covered entrance, and two potted plants on either side.

2. Hotel Albani Firenze

Hotel Albani Firenze
4.0 star property
Historic Centre of Florence
9.2 out of 10, Wonderful, (1,001 reviews)
"Clean hotel close to central train station and a short walk from most sights in the city."
Canada
Peter
The price is ฿3,986
฿4,913 total
includes taxes & fees
1 Dec - 2 Dec
Hotel Albani Firenze
A rooftop terrace with a hot tub, lounge chairs, and potted plants.

3. Hotel Machiavelli Palace

Hotel Machiavelli Palace
3.0 star property
Historic Centre of Florence
8.4 out of 10, Very good, (268 reviews)
"It was a good experience in general. Good breakfast"
Mexico
Julian
The price is ฿2,367
฿3,055 total
includes taxes & fees
15 Nov - 16 Nov
Hotel Machiavelli Palace
A modern hotel lobby with a large mural, seating areas, and a reception desk.

4. Mercure Firenze Centro

Mercure Firenze Centro
4.0 star property
Historic Centre of Florence
9.0 out of 10, Wonderful, (915 reviews)
"Fantastic hotel, some of the best views on the island!"
United States
Valon
The price is ฿4,612
฿5,599 total
includes taxes & fees
22 Nov - 23 Nov
Mercure Firenze Centro
A table set for breakfast with a view of historic buildings and mountains.

5. Hotel Kraft

Hotel Kraft
4.0 star property
Historic Centre of Florence
9.4 out of 10, Exceptional, (680 reviews)
"We had an awesome 2 night stay! Beautiful, quiet location. Rooms are gorgeous. The rooftop bar and pool were another plus! Highly recommend."
United States
Sean
The price is ฿3,532
฿4,414 total
includes taxes & fees
29 Nov - 30 Nov
Hotel Kraft
A dining area with a table set for four, a red coffee machine, and a buffet with fruits and pastries.

6. B&B Il Marzocco

B&B Il Marzocco
Historic Centre of Florence
9.0 out of 10, Wonderful, (266 reviews)
"The staff was very accommodating and helpful. I would recommend this place. It’s very comfortable well located place to stay in Florence. The sheets and pillows could be a little softer, but that’s the only issue"
United States
Raymond
The price is ฿2,700
฿3,421 total
includes taxes & fees
15 Nov - 16 Nov
B&B Il Marzocco
A spacious lounge area with a high ceiling, large windows, and a seating arrangement featuring blue upholstered sofas and round tables with blue tablecloths.

7. 25hours Hotel Florence Piazza San Paolino

25hours Hotel Florence Piazza San Paolino
4.0 star property
Historic Centre of Florence
9.4 out of 10, Exceptional, (1,003 reviews)
"We have stayed here 3 times over the last few years and love the hotel. Conveniently located , close to the train station and wonderful staff"
United States
Timothy
The price is ฿5,617
฿6,705 total
includes taxes & fees
28 Nov - 29 Nov
25hours Hotel Florence Piazza San Paolino
A modern hotel room with a large bed, a desk, a chair, and a TV.

8. Hotel Cosimo De' Medici

Hotel Cosimo De' Medici
3.0 star property
Historic Centre of Florence
8.8 out of 10, Excellent, (719 reviews)
"Booked last minute and was very please with the location, price, service, room size and cleanness. We would definitely stay again."
United States
Yolanda
The price is ฿3,020
฿3,773 total
includes taxes & fees
15 Nov - 16 Nov
Hotel Cosimo De' Medici
A wooden table with drinks and snacks on a balcony overlooking a cityscape with a prominent dome building.

9. Novella House

Novella House
Historic Centre of Florence
9.0 out of 10, Wonderful, (363 reviews)
"A beautiful place with an amazing staff and everything you need. Would definitely stay here again and would recommend it to everyone!"
United States
Zeus
The price is ฿2,137
฿3,365 total
includes taxes & fees
30 Nov - 1 Dec
Novella House
A compact room with a desk, chair, and bunk beds.

10. YellowSquare Florence

YellowSquare Florence
Santa Maria Novella
9.6 out of 10, Exceptional, (52 reviews)
"Best hostel I've ever stayed in. Super clean, nice staff, bunk beds are well designed to preserve privacy. Nice bars and shared spaces."
United States
Marie
The price is ฿1,856
฿2,343 total
includes taxes & fees
12 Nov - 13 Nov
YellowSquare Florence
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Santa Maria Novella

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A reception area with a marble counter, a large mirror, and two potted plants.
Hotel Boccaccio
3.5 star property
9.2
Wonderful
1,021 reviews
View
A hotel entrance with a double door, a covered entrance, and two potted plants on either side.
Hotel Albani Firenze
4.0 star property
9.2
Wonderful
1,001 reviews
View
A rooftop terrace with a hot tub, lounge chairs, and potted plants.
Hotel Machiavelli Palace
3.0 star property
8.4
Very good
268 reviews
View
A modern hotel lobby with a large mural, seating areas, and a reception desk.
Mercure Firenze Centro
4.0 star property
9.0
Wonderful
915 reviews
View
A table set for breakfast with a view of historic buildings and mountains.
Hotel Kraft
4.0 star property
9.4
Exceptional
680 reviews
View

Top Santa Maria Novella Hotel Reviews

A compact room with a desk, chair, and bunk beds.
YellowSquare Florence

YellowSquare Florence

YellowSquare Florence
Santa Maria Novella

10/10 Excellent

Friendly staff and didnt expected to have free drink and pasta!!! Easy But just the room a bit smell Except from that everything all good
United Kingdom
Seolong
Reviewed January 26, 2026
YellowSquare Florence

Frequently Asked Questions

Looking for LGBTQ-friendly accommodation in Santa Maria Novella?

Whether you are travelling with your partner or flying solo, you'll find gay-friendly hotels in Santa Maria Novella on our website. Staying in this walkable area will give you access to its museums and cathedral.

What is the favourite LGBTQ-friendly hotel in Santa Maria Novella?

Hotel Albani Firenze is a top LGBTQ-friendly hotel that features free Wi-Fi and a fitness centre. YellowSquare Florence and 25hours Hotel Florence Piazza San Paolino are other good options for your holiday.

How many gay-friendly hotels are there in Santa Maria Novella?

There are currently 23 gay-friendly accommodation options in Santa Maria Novella.

What should I do while I'm visiting Santa Maria Novella?

During your trip, get out and enjoy everything Santa Maria Novella has to offer. You and your travelling companions may want to visit Piazza di Santa Maria Novella, Palazzo dei Congressi and Fortezza da Basso. While you're here, create some great memories of your trip with stops at Piazza Ognissanti, Basilica of Santa Maria Novella and Via Faenza.

What is a gay-friendly hotel in Santa Maria Novella?

LGBTQ-friendly hotels, also known as gay-friendly hotels, welcome all travellers who identify as LGBTQIA+. Expedia has worked with the International Gay and Lesbian Travel Association (IGLTA) to compile a selection of LGBTQ-friendly hotels worldwide. In Santa Maria Novella, hotels affiliated with IGLTA will provide lesbian, gay, bisexual and transgender adventurers with the information needed to design the trip of a lifetime.

What can I expect from a gay-friendly hotel in Santa Maria Novella?

Take a holiday from the ordinary; stay at an LGBTQ-friendly hotel in Santa Maria Novella, and you won’t have to hide your same-sex relationship or your sexuality when you check in. Many of our LGBTQ-friendly accommodation options offer community-specific packages, exclusive tours and opportunities for social interaction.