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Our top choices for Santa Lucia hotels

Caportigia Boutique Hotel

Caportigia Boutique Hotel
5.0 star property
Santa Lucia
9.4 out of 10, Exceptional, (258 reviews)
"Fine quality hotel with exceptional service. "
United States
Peter
The price is ฿3,582
฿4,305 total
includes taxes & fees
26 Jan - 27 Jan
Caportigia Boutique Hotel

Grande Albergo Alfeo

Grande Albergo Alfeo
4.0 star property
Santa Lucia
8.6 out of 10, Excellent, (652 reviews)
"The room was nice the location convenient. No view to speak of but centrally located"
Canada
Eric
The price is ฿3,101
฿3,535 total
includes taxes & fees
23 Jan - 24 Jan
Grande Albergo Alfeo

Gymnasium

Gymnasium
3.0 star property
Santa Lucia
8.8 out of 10, Excellent, (40 reviews)
"Nice kitchen area, centrally located."
United States
Richard
The price is ฿2,156
฿2,457 total
includes taxes & fees
1 Feb - 2 Feb
Gymnasium

Lakkios

Lakkios
3.0 star property
Santa Lucia
9.0 out of 10, Wonderful, (63 reviews)
"Nice, central, clean, easy to park, quiet during the night, staff was welcoming, nice breakfast with view - excellent choice!"
Norway
Jon-Kåre
The price is ฿2,985
฿3,403 total
includes taxes & fees
20 Jan - 21 Jan
Lakkios

Piccolo Hotel Casa Mia

Piccolo Hotel Casa Mia
3.0 star property
Santa Lucia
8.6 out of 10, Excellent, (374 reviews)
"The staff is extremely nice and friendly and you feel welcome. "
Canada
Florentina
The price is ฿1,791
฿2,042 total
includes taxes & fees
1 Feb - 2 Feb
Piccolo Hotel Casa Mia

Nostos rooms & Apartments

Nostos rooms & Apartments
3.0 star property
Santa Lucia
9.0 out of 10, Wonderful, (274 reviews)
"Welcoming, room, staff and area around definitely stood out!"
Canada
Aina
The price is ฿1,990
฿2,268 total
includes taxes & fees
1 Feb - 2 Feb
Nostos rooms & Apartments

Giuggiulena Villa

Giuggiulena Villa
3.0 star property
Santa Lucia
10.0 out of 10, Exceptional, (126 reviews)
"Fantastic stay. Made to feel very welcome and what a lovely relaxing place to stay. Evening meal was exceptional. "
United States
Paul
The price is ฿7,537
฿8,592 total
includes taxes & fees
7 Feb - 8 Feb
Giuggiulena Villa

Re Dionisio Luxury Suites

Re Dionisio Luxury Suites
3.0 star property
Santa Lucia
8.8 out of 10, Excellent, (57 reviews)
"Spacious room, dated but comfortable."
United States
Kenneth
The price is ฿10,215
฿11,601 total
includes taxes & fees
10 Feb - 11 Feb
Re Dionisio Luxury Suites

Calafatari B&B

Calafatari B&B
3.0 star property
Santa Lucia
10.0 out of 10, Exceptional, (11 reviews)
"We had a lovely stay. Anna was very welcoming. We had a lovely large clean room and a nice modern bathroom. She went all out for breakfast. "
United States
Carl and Lina
Calafatari B&B

B&B Nike

B&B Nike
Santa Lucia
8.8 out of 10, Excellent, (75 reviews)
"Clean, good location. "
United States
Salvatore
The price is ฿3,095
฿3,529 total
includes taxes & fees
17 Feb - 18 Feb
B&B Nike

Isonzo Suites

Isonzo Suites
Santa Lucia
8.4 out of 10, Very good, (5 reviews)
"."
Italy
Gianluca
The price is ฿2,013
฿3,377 total
includes taxes & fees
25 Jan - 26 Jan
Isonzo Suites

Hotel Palazzo Cavalieri

Hotel Palazzo Cavalieri
4.0 star property
Santa Lucia
8.8 out of 10, Excellent, (39 reviews)
"Enjoyed our stay, nice comfortable room and bed. Very nice breakfast buffet. Within a quick 5 min walk to Ortigia Island, also walkable to train and bus station. Would stay here again."
United States
Jennifer
The price is ฿3,157
฿3,599 total
includes taxes & fees
20 Jan - 21 Jan
Hotel Palazzo Cavalieri

B&B Siracusa

B&B Siracusa
Santa Lucia
9.0 out of 10, Wonderful, (59 reviews)
"Good location, very modern clean accommodation."
Canada
Malcolm
The price is ฿2,919
฿3,327 total
includes taxes & fees
20 Jan - 21 Jan
B&B Siracusa

AmaCasa Siracusa

AmaCasa Siracusa
Santa Lucia
10.0 out of 10, Exceptional, (1 review)
"Siamo stati molto bene, la struttura internamente è abbastanza ammodernata e l'accesso è stato"
Italy
Alessandro
The price is ฿2,985
฿3,403 total
includes taxes & fees
20 Jan - 21 Jan
AmaCasa Siracusa

Regina Margherita

Regina Margherita
Santa Lucia
8.0 out of 10, Very good, (14 reviews)
"The area is so close to the Ortigia Island where the beautiful cathedral and Doumo are. Lovely walk around the entire island and areas to go in the water If you like. Many dining options and shopping too. Wonderful area!"
United States
Laura
The price is ฿2,019
฿2,302 total
includes taxes & fees
1 Feb - 2 Feb
Regina Margherita

San Nicola Rooms Siracusa

San Nicola Rooms Siracusa
Santa Lucia
9.4 out of 10, Exceptional, (3 reviews)
"Stanza molto bella e nuova, ottimi arredi, letto comodo e cuscini comodi, belle tende, bagno bello e pulito, specchio del bagno fantastico con una luce bellissima regolabile a led. Mi sono trovato bene, il personale gentilissimo in particolare la ragazza (Lucia se non ricordo male) super cordiale!"
Italy
Davide Angelo
The price is ฿2,507
฿2,858 total
includes taxes & fees
2 Feb - 3 Feb
San Nicola Rooms Siracusa

Agorà

Agorà
Santa Lucia
10.0 out of 10, Exceptional, (2 reviews)
"Trevligt, rent, bra service. Hade turen att få balkong. "
Sweden
Olof
The price is ฿2,952
฿3,365 total
includes taxes & fees
20 Jan - 21 Jan
Agorà

Hotel Mediterraneo

Hotel Mediterraneo
3.0 star property
Santa Lucia
7.8 out of 10, Good, (123 reviews)
"Very friendly and helpful staff."
United States
David
The price is ฿1,843
฿2,101 total
includes taxes & fees
1 Feb - 2 Feb
Hotel Mediterraneo

Populus

Populus
1.0 star property
Santa Lucia
7.8 out of 10, Good, (74 reviews)
"Just stay somewhere else, plain and simple."
United States
Thomas
The price is ฿2,686
฿3,063 total
includes taxes & fees
2 Feb - 3 Feb
Populus

Casa Miranda Boutique

Casa Miranda Boutique
Santa Lucia
6.0 out of 10, (1 review)
The price is ฿6,209
฿7,194 total
includes taxes & fees
20 Jan - 21 Jan
Casa Miranda Boutique
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Lucia

Find the best Santa Lucia areas for the activities you enjoy most.

Ortigia

Ortigia is popular for its seaside views, and if you're looking for more to see and do, you might think about a trip to Cathedral of Syracuse or Piazza del Duomo.

Neapolis

While visiting Neapolis, you might make a stop by sights like Roman Amphitheatre of Syracuse and Archaeological Park of Neapolis.

Tiche

Gardens and restaurants are notable features of Tiche. You might consider stopping by Ionian Sea while you're exploring the neighbourhood.

Grottasanta

Grottasanta is noteworthy for its historical sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.

Acradina

You'll enjoy the churches and seaside views in Acradina. You might want to make time for a stop at Ionian Sea or Capuchin Quarry.

Top Santa Lucia Hotel Reviews

Frequently asked questions

What is Santa Lucia like?
Santa Lucia is a neighbourhood that people enjoy for its interesting historical sites. Are you looking for Santa Lucia travel tips? Make sure that you visit Porto Piccolo and Ionian Sea while you're in the neighbourhood.
Where is the best hotel for a stay in Santa Lucia?
Based on Expedia customer reviews, Caportigia Boutique Hotel is the highest ranked property in Santa Lucia. This property offers a restaurant and free parking. Other top choices in the neighbourhood include Lakkios and La casa di Aneupe.
How many hotels will I find in Santa Lucia?
Expedia has 289 hotels and other accommodation options in Santa Lucia to choose from, making this an ideal home base for exploring the greater Syracuse area.
If I need to cancel my hotel reservation in Santa Lucia, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to review the best options available in Santa Lucia.
What are the top things to see and do in Santa Lucia?
Landmarks in Santa Lucia that you won't want to miss include Syracuse Forum Ruins and Santa Lucia Bridge. Porto Piccolo and Ionian Sea are some other stops worth a visit in the neighbourhood. A few places to visit in the area around Santa Lucia include Piazza Santa Lucia, Santa Lucia al Sepolcro Basilica and Madonna delle Lacrime. When you're sightseeing in Syracuse, Papyrus Museum and Museo Archeologico Regionale Paolo Orsi are also worth a stop.