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Our top choices for Santa Fe hotels

Hotel Once22

Hotel Once22
3.0 star property
8.9 km from Santa Fe
9.4 out of 10, Exceptional, (57 reviews)
"The rooftop space was really nice to hang out and take pictures. It’s covered so it’s nice. Rooms were clean, staff is very helpful and very nice. I will be staying there again shortly."
United States
Seth
The price is ฿1,860
฿1,860 total
17 Mar - 18 Mar
Hotel Once22

Fairfield by Marriott Medellin Sabaneta

Fairfield by Marriott Medellin Sabaneta
3.5 star property
8.4 km from Santa Fe
9.4 out of 10, Exceptional, (259 reviews)
"Nice staff, good food, easy onsite parking and great location "
United States
Lynn
The price is ฿2,616
฿2,616 total
21 Mar - 22 Mar
Fairfield by Marriott Medellin Sabaneta

Arame Hotel

Arame Hotel
3.0 star property
5.6 km from Santa Fe
9.2 out of 10, Wonderful, (196 reviews)
"Excellent place to stay, clean, comfortable and the breakfast was delicious "
United States
Giovanny
The price is ฿1,915
฿1,915 total
29 Mar - 30 Mar
Arame Hotel

Hotel Latino

Hotel Latino
2.0 star property
La Candelaria, 3.4 km from Santa Fe
7.8 out of 10, Good, (37 reviews)
"Everything was good. Great value for money"
United States
Calvin
The price is ฿691
฿691 total
17 Mar - 18 Mar
Hotel Latino

Hotel Central Plaza Medellin

Hotel Central Plaza Medellin
3.0 star property
3.9 km from Santa Fe
8.0 out of 10, Very good, (348 reviews)
"Excellent place to stay.. I’ll be back ."
United States
Isabel
The price is ฿1,657
฿1,657 total
18 Mar - 19 Mar
Hotel Central Plaza Medellin

La Quinta by Wyndham Medellin

La Quinta by Wyndham Medellin
3.5 star property
San Diego, 1.9 km from Santa Fe
8.8 out of 10, Excellent, (1,003 reviews)
"Best hotel"
United States
Wilfred
The price is ฿2,525
฿2,525 total
26 Mar - 27 Mar
La Quinta by Wyndham Medellin

Hotel Sixtina Plaza Medellin

Hotel Sixtina Plaza Medellin
3.0 star property
3.8 km from Santa Fe
8.4 out of 10, Very good, (143 reviews)
"Hotel is in good location,many stores around it,excellent staff service."
United States
Edgardo
The price is ฿1,191
฿1,191 total
17 Mar - 18 Mar
Hotel Sixtina Plaza Medellin

Hotel Ryo 74B Suites by Growing Group

Hotel Ryo 74B Suites by Growing Group
3.0 star property
Laureles, 2 km from Santa Fe
9.6 out of 10, Exceptional, (24 reviews)
"Clean rooms and friendly staff. Would stay there again"
United States
Iris
The price is ฿1,570
฿1,570 total
25 Mar - 26 Mar
Hotel Ryo 74B Suites by Growing Group

Landmark Hotel

Landmark Hotel
4.0 star property
Manila, 1.4 km from Santa Fe
9.6 out of 10, Exceptional, (292 reviews)
"Very nice hotel! Rooms were nice and everything about our stay was enjoyable!"
Canada
Nuventhran
The price is ฿4,029
฿4,029 total
14 Apr - 15 Apr
Landmark Hotel

ibis Medellin

ibis Medellin
3.0 star property
0.8 km from Santa Fe
8.8 out of 10, Excellent, (1,001 reviews)
"My second time in this hotel and love the fact that is centrally located. Will definitely recommend it. "
United States
Enrique
The price is ฿2,363
฿2,363 total
20 Mar - 21 Mar
ibis Medellin

Hotel Attic 33

Hotel Attic 33
3.0 star property
Laureles, 1.9 km from Santa Fe
9.2 out of 10, Wonderful, (44 reviews)
"Clean room, staff, love the place."
United States
Luis
The price is ฿1,439
฿1,439 total
1 Apr - 2 Apr
Hotel Attic 33

The Somos Bold Hotel

The Somos Bold Hotel
4.0 star property
Manila, 1.4 km from Santa Fe
9.4 out of 10, Exceptional, (250 reviews)
"Clean, great service and nice hotel. It’s small but it’s well located. "
Canada
Matthew
The price is ฿3,254
฿3,254 total
9 Apr - 10 Apr
The Somos Bold Hotel

The Host Medellin Only Adults

The Host Medellin Only Adults
3.0 star property
Astorga, 1.8 km from Santa Fe
9.4 out of 10, Exceptional, (43 reviews)
"Great ambience and room, excellent breakfast "
United States
Shailendra
The price is ฿5,108
฿5,108 total
31 Mar - 1 Apr
The Host Medellin Only Adults

Hotel Alcaravan Medellín

Hotel Alcaravan Medellín
3.0 star property
3.7 km from Santa Fe
7.8 out of 10, Good, (272 reviews)
"Staff was very helpful and caring "
United States
Gloria
The price is ฿1,248
฿1,248 total
17 Mar - 18 Mar
Hotel Alcaravan Medellín

Heiss Hotel By Jalo

Heiss Hotel By Jalo
4.0 star property
El Poblado, 1.3 km from Santa Fe
9.2 out of 10, Wonderful, (1,278 reviews)
"Great place to stay staff was amazing very nice area!"
Canada
Sean
The price is ฿2,173
฿2,173 total
5 Apr - 6 Apr
Heiss Hotel By Jalo

Nomada Hotel Origen

Nomada Hotel Origen
3.0 star property
Manila, 1.4 km from Santa Fe
9.2 out of 10, Wonderful, (123 reviews)
"Lovely place, great service, awesome food!"
United States
Alejandro
The price is ฿2,438
฿2,438 total
17 Mar - 18 Mar
Nomada Hotel Origen

Hotel Estelar Milla de Oro

Hotel Estelar Milla de Oro
3.5 star property
Patio Bonito, 2.5 km from Santa Fe
9.0 out of 10, Wonderful, (940 reviews)
"Very friendly staff and the hotel is a top class."
United States
Ariel
The price is ฿4,102
฿4,102 total
5 Apr - 6 Apr
Hotel Estelar Milla de Oro

Isak Hotel & Golf Airport

Isak Hotel & Golf Airport
3.0 star property
16.3 km from Santa Fe
9.2 out of 10, Wonderful, (635 reviews)
"Excellent location, nice staff, clean rooms. Convenient shuttle"
United States
ANGELA
The price is ฿2,734
฿2,734 total
17 Mar - 18 Mar
Isak Hotel & Golf Airport

Hotel Poblado Plaza

Hotel Poblado Plaza
3.5 star property
2.6 km from Santa Fe
9.2 out of 10, Wonderful, (764 reviews)
"Very nice hotel "
United States
Yun
The price is ฿3,635
฿3,635 total
12 Apr - 13 Apr
Hotel Poblado Plaza

Hotel Santiago de Arma

Hotel Santiago de Arma
3.0 star property
16.7 km from Santa Fe
9.2 out of 10, Wonderful, (945 reviews)
"Staff was helpful and quick with check in. Decent room and close to the airport. "
United States
Stephanie
The price is ฿4,085
฿4,085 total
17 Mar - 18 Mar
Hotel Santiago de Arma
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Fe

Find the best Santa Fe areas for the activities you enjoy most.

El Poblado

El Poblado is highly notable for its popular shops, and you might want to visit top sights like Golden Mile and Oviedo Shopping Center. See more of Medellín by jumping on the metro at Poblado Station or Aguacatala Station.

Laureles

Laureles is known for its ample dining options, and you can make a stop by Unicentro Shopping Center and Belén Andrés Escobar Sports Complex while in the area.

Provenza

If you're looking for some top things to see and do in Provenza and surrounding area, you can visit Golden Mile and Oviedo Shopping Center.

Laureles - Estadio

While you're in Laureles - Estadio, take in top sights like Atanasio Giradot Stadium or Unicentro Shopping Center, and hop on the metro to see more of the city at Estadio Station or Suramericana Station.

Zona Rosa

When in Zona Rosa, you can plan a visit to Golden Mile and Oviedo Shopping Center, some noteworthy sights in the nearby area.

Top Santa Fe Hotel Reviews

Frequently asked questions

What's it like in Santa Fe?
You'll be sure to have fun exploring Medellín's Santa Fe neighbourhood. Consider a visit to Santa Fe Zoological Park as part of your Santa Fe travel plans.
How many hotels will I be able to find in Santa Fe?
If you're searching for places to stay in Medellín, choose from one of Expedia's 12 hotels and other accommodation options in Santa Fe.
If I need to cancel my hotel reservation in Santa Fe, will I receive a refund?
Yes, you'll find most room reservations are refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and receive a refund within 24 hours of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to review the top deals on offer in Santa Fe.
What is there to do around this Medellín neighbourhood?
Santa Fe Zoological Park is an attraction you might want to check out while you're in Santa Fe. While you're out sightseeing, Medellin's Museum of Modern Art and Monterrey Comercial Mall are a couple of additional sights to visit in Medellín.