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1 Aug - 2 Aug
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Top 10 Santa Cruz hotels and places to stay

Isak Hotel & Golf Airport
Couples treatment room(s), hot stone massages, Thai massages

Isak Hotel & Golf Airport

3.0 star property
9.4 out of 10, Exceptional, (459)
"Hotel staff extremely courteous, amazing breakfast will be back for sure"
The price is ฿2,722
฿2,722 total
9 Aug - 10 Aug
Isak Hotel & Golf Airport
Hotel Santiago de Arma
1 bedroom, in-room safe, desk, free WiFi

Hotel Santiago de Arma

3.0 star property
9.2 out of 10, Wonderful, (849)
"Very nice and near to the airport"
Hotel Santiago de Arma
Hotel Provenza Garden
Front of property

Hotel Provenza Garden

3.0 star property
8.2 out of 10, Very good, (146)
"I have been coming to Medellin for over 2 years now and this hotel is such a perfect location. Close to everything and in a safe area! Thank you to the staff for their hospitality."
The price is ฿1,901
฿1,901 total
3 Aug - 4 Aug
Hotel Provenza Garden
Golden Valley Hotel
Restaurant

Golden Valley Hotel

2.5 star property
9.4 out of 10, Exceptional, (72)
"Great hotel "
The price is ฿2,975
฿3,209 total
25 Aug - 26 Aug
Golden Valley Hotel
Hotel Florencia Plaza
Indoor spa tub

Hotel Florencia Plaza

3.0 star property
8.4 out of 10, Very good, (69)
"Great staff and a great location. I'll be staying here again."
The price is ฿1,591
฿1,591 total
17 Aug - 18 Aug
Hotel Florencia Plaza
Marquee Hotel
Outdoor pool, free pool cabanas

Marquee Hotel

3.0 star property
9.4 out of 10, Exceptional, (33)
"Excelente Hotel "
The price is ฿5,369
฿5,369 total
1 Sept - 2 Sept
Marquee Hotel
First Class Hotel
Panoramic Apartment, Balcony, City View | Living area | 50-inch Smart TV with digital channels, Netflix, streaming services

First Class Hotel

3.0 star property
9.0 out of 10, Wonderful, (206)
"Great location"
The price is ฿2,154
฿2,154 total
2 Aug - 3 Aug
First Class Hotel
ibis budget Medellín Itagüí Metro
Restaurant

ibis budget Medellín Itagüí Metro

3.0 star property
9.0 out of 10, Wonderful, (378)
"Great location outside the tourist area. "
The price is ฿1,260
฿1,260 total
16 Aug - 17 Aug
ibis budget Medellín Itagüí Metro
Heiss Hotel - By Jalo
Outdoor pool, pool umbrellas, lifeguards on site

Heiss Hotel - By Jalo

4.0 star property
9.2 out of 10, Wonderful, (707)
"Great stay very clean beautiful area"
The price is ฿3,327
฿3,327 total
2 Aug - 3 Aug
Heiss Hotel - By Jalo
Sonata 44 Hotel Laureles
Restaurant

Sonata 44 Hotel Laureles

3.0 star property
9.0 out of 10, Wonderful, (51)
"Amazing hotel comfortable room "
The price is ฿2,624
฿2,624 total
18 Aug - 19 Aug
Sonata 44 Hotel Laureles
Hotel via 45 Centro
1 bedroom, blackout curtains, soundproofing, iron/ironing board

Hotel via 45 Centro

3.5 star property
7.6 out of 10, Good, (137)
"Great staff!"
The price is ฿713
฿713 total
2 Aug - 3 Aug
Hotel via 45 Centro
THE HARBOUR HOTEL
Exterior

THE HARBOUR HOTEL

2.5 star property
7.8 out of 10, Good, (34)
"Nice"
THE HARBOUR HOTEL
Faranda Collection Medellin, a Member of Radisson Individuals
Dining

Faranda Collection Medellin, a Member of Radisson Individuals

4.0 star property
9.4 out of 10, Exceptional, (189)
"I liked the location and amenities."
The price is ฿3,558
฿3,558 total
15 Aug - 16 Aug
Faranda Collection Medellin, a Member of Radisson Individuals
Indie Universe Creative Hotel
Exclusive Studio Suite | 1 bedroom, premium bedding, individually decorated

Indie Universe Creative Hotel

3.0 star property
8.4 out of 10, Very good, (139)
"Very nice location "
Indie Universe Creative Hotel
The Somos Bold Hotel
Terrace/patio

The Somos Bold Hotel

4.0 star property
9.2 out of 10, Wonderful, (188)
"Jacuzzi, Jacuzzi, Jacuzzi!"
The Somos Bold Hotel
ANTÍPODA HOTEL
Property grounds

ANTÍPODA HOTEL

3.0 star property
9.2 out of 10, Wonderful, (143)
"Amazing stay and very kind staff. Always happy to help you and they ensure that you’re feel comfy/safe. I would stay here again!"
The price is ฿1,585
฿1,976 total
1 Sept - 2 Sept
ANTÍPODA HOTEL
Los Patios Cool Living
Outdoor pool

Los Patios Cool Living

3.0 star property
9.4 out of 10, Exceptional, (401)
"Loved the art painted on the walls and the beautiful nature decor."
Los Patios Cool Living
HOTEL SELIS
Front of property

HOTEL SELIS

3.5 star property
9.6 out of 10, Exceptional, (203)
"Great place"
The price is ฿2,848
฿2,848 total
1 Sept - 2 Sept
HOTEL SELIS
Hotel Nutibara
Lobby sitting area

Hotel Nutibara

3.0 star property
7.2 out of 10, Good, (511)
"Location and staff were excellent. "
Hotel Nutibara
Hotel Celestino Boutique
Exterior

Hotel Celestino Boutique

3.0 star property
9.4 out of 10, Exceptional, (144)
"Amazing everything was close by "
Hotel Celestino Boutique
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Santa Cruz

Head to Medellin Botanical Garden and Arvi Park—just two of the sights around Santa Cruz.

See all hotels in Santa Cruz

Top Santa Cruz Hotel Reviews

Heiss Hotel

Heiss Hotel

10/10 Excellent
"The hotel was fantastic, the service was excellent, and the food was outstanding—especially the restaurant with the delicious pizza options."
Tony 4-night trip
Posted 19 hours ago
Heiss Hotel

Frequently asked questions

Where is the best place to stay in Santa Cruz?

Located 5.9 mi (9.4 km) from the heart of Santa Cruz, Heiss Hotel - By Jalo is a top choice for your stay, based on our traveller data. Two other options for your stay in the area are Hotel Dorado La 70 and York Luxury Suites Medellín. See all available top hotels, or vacation rentals in Santa Cruz.

What are some of the best holiday rentals that Santa Cruz has to offer?

EP Casa Uribe Architecture Art & Nature: This holiday home rental outside Santa Cruz is located in a shopping district, and has an outdoor pool, a balcony and free WiFi to put you at ease in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. See all vacation rentals in Santa Cruz.

If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?

Yes! Most hotel bookings are fully refundable if you cancel before the hotel’s cancellation deadline, which often is within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you might be able to cancel it and receive a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.

What are some hotels with pools in Santa Cruz?

Novotel Medellín El Tesoro: 4-star hotel located near El Tesoro Shopping Park. Features a rooftop terrace, a pool and free self-parking. NH Collection Medellín Royal and The Click Clack Hotel Medellin are two additional hotels with an on-site pool. View all hotels with pools in Santa Cruz.

What is staying in Santa Cruz like?

Visitors will definitely enjoy all that Santa Cruz has to offer. In Santa Cruz, there are 2 hotels and other accommodation options to choose from. Find out more about Santa Cruz.

What should I do while I'm visiting Santa Cruz?

Places to visit in the wider area include Medellin Botanical Garden, Arvi Park and Medellin Cathedral. You'll also find Antioquia Museum and Botero Plaza in the area. Take a look at what more there is to see and do in Expedia's Santa Cruz guide.

How can I get around Santa Cruz?

Make your way to Andalucía MetroCable Station for metro travel. If you want to venture out around the area, you may want a rental car in Santa Cruz for your journey.

What's the seasonal weather in Santa Cruz?

The hottest months are usually August and July, with an average temperature of 19°C, while the coldest months are December and January, with an average of 18°C. The rainiest months in Santa Cruz are May, April, October and November, with each month seeing an average of 406 mm of rainfall.