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Check prices for these dates

Tonight
4 Oct - 5 Oct
Tomorrow
5 Oct - 6 Oct
Next weekend
10 Oct - 12 Oct
In two weeks
17 Oct - 19 Oct

Top Holiday Rentals in Santa Cruz

York Luxury Suites Medellín
Indoor pool, outdoor pool, pool loungers

York Luxury Suites Medellín

4.0 star property
9.6 out of 10, Exceptional, (1343)
"Great hotel! "
York Luxury Suites Medellín
Sites Hotel
Rooftop pool

Sites Hotel

4.0 star property
9.2 out of 10, Wonderful, (1080)
"excellent service & comfortable suites"
The price is ฿3,138
฿3,138 total
5 Oct - 6 Oct
Sites Hotel
Factory Lofts
Loft, 1 Double Bed | 1 bedroom, Egyptian cotton sheets, premium bedding, down duvets

Factory Lofts

4.0 star property
9.8 out of 10, Exceptional, (87)
"Wonderful place in a walkable area. "
The price is ฿1,588
฿2,340 total
30 Oct - 31 Oct
Factory Lofts
Haven
Lobby

Haven

4.0 star property
8.8 out of 10, Excellent, (614)
"I loved everything about my stay. I'm definitely coming back."
The price is ฿3,093
฿3,093 total
8 Oct - 9 Oct
Haven
Royal Living Poblado
Basic Studio Suite, City View | Terrace/patio

Royal Living Poblado

4.0 star property
9.2 out of 10, Wonderful, (45)
"Great place"
Royal Living Poblado
Apartment Go Living & Suites by HOUSY HOST
Coffee shop

Apartment Go Living & Suites by HOUSY HOST

3.5 star property
8.4 out of 10, Very good, (376)
"Great stay!! I always stay here when I visit Medellin "
Apartment Go Living & Suites by HOUSY HOST
Botánica Manila by HOUSY HOST
Studio Suite (102) | Television

Botánica Manila by HOUSY HOST

3.0 star property
9.0 out of 10, Wonderful, (41)
"Very clean rooms and comfort! "
Botánica Manila by HOUSY HOST
Kyux by Jalo
Deluxe Apartment | Living area | 55-inch Smart TV with cable channels, streaming services

Kyux by Jalo

4.0 star property
9.4 out of 10, Exceptional, (30)
"Great place"
Kyux by Jalo
Estelar Apartamentos Medellin
Standard Twin Room, 1 Single Bed (Superior Apartment Twin Bed) | 7 bedrooms, premium bedding, memory-foam beds, in-room safe

Estelar Apartamentos Medellin

3.5 star property
8.8 out of 10, Excellent, (444)
"Is a perfect hitel as it's close to one of the most popular malls which is Santa Fé and is easy accessible "
The price is ฿3,009
฿3,009 total
3 Nov - 4 Nov
Estelar Apartamentos Medellin
Wake Living
Apartment, 1 Bedroom | Living area | Flat-screen TV

Wake Living

4.0 star property
8.8 out of 10, Excellent, (153)
"Amazing Property would stay again "
Wake Living
zenia
Staircase

zenia

3.0 star property
9.2 out of 10, Wonderful, (31)
"Seamless and excellent communication, will book again if I am in the area. "
The price is ฿817
฿817 total
5 Oct - 6 Oct
zenia
Origen Local Suites
Standard Studio | Street view

Origen Local Suites

3.0 star property
9.4 out of 10, Exceptional, (176)
"Good location I always stay at this hotel no complain highly recommended 👍"
The price is ฿1,716
฿1,716 total
6 Oct - 7 Oct
Origen Local Suites
Seissta Medellin
Restaurant

Seissta Medellin

4.0 star property
9.2 out of 10, Wonderful, (196)
"Great place"
The price is ฿3,227
฿3,227 total
29 Oct - 30 Oct
Seissta Medellin
Wake BioHotel
Restaurant

Wake BioHotel

5.0 star property
8.4 out of 10, Very good, (11)
"Great stay near all the attractions. Great stay "
The price is ฿7,910
฿8,328 total
12 Oct - 13 Oct
Wake BioHotel
Alcázar de Oviedo By EE Hotels
Deluxe Apartment | Living area | 43-inch Smart TV with satellite channels, TV

Alcázar de Oviedo By EE Hotels

3.0 star property
9.4 out of 10, Exceptional, (156)
"I had a great time at the hotel. The rooms were comfortable, and the staff were very kind, thanks to Juliana and Daisy especially for their attention"
The price is ฿3,016
฿3,016 total
5 Oct - 6 Oct
Alcázar de Oviedo By EE Hotels
Quadrato Studios
Outdoor spa tub

Quadrato Studios

3.0 star property
9.4 out of 10, Exceptional, (60)
"This place was amazing Great staff"
Quadrato Studios
Aparta Hotel Portal del Rodeo
Apartment, Multiple Beds | Dining room

Aparta Hotel Portal del Rodeo

3.5 star property
9.0 out of 10, Wonderful, (239)
"Everything was good .. 👍 nice place to stay with family very safe.. nice people.."
The price is ฿1,985
฿1,985 total
15 Oct - 16 Oct
Aparta Hotel Portal del Rodeo
Apartment 301
50-inch flat-screen TV with cable channels, TV

Apartment 301

3.0 star property
9.8 out of 10, Exceptional, (6)
"It was nice "
Apartment 301
Laureles Guest House - LGH Hotel
Lobby lounge

Laureles Guest House - LGH Hotel

3.5 star property
9.2 out of 10, Wonderful, (70)
"Staff was excellent. Helpful, supportive, kind. Free breakfast was made fresh as ordered, and delicious."
The price is ฿1,274
฿1,274 total
7 Oct - 8 Oct
Laureles Guest House - LGH Hotel
Provenza Lofts
2-Bedroom apartment with jacuzzi | Living area

Provenza Lofts

3.0 star property
8.2 out of 10, Very good, (138)
"Great stay"
The price is ฿2,436
฿2,436 total
7 Oct - 8 Oct
Provenza Lofts
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

The Charlee Hotel

The Charlee Hotel

10/10 Excellent
"Excellent service. "
Ronnie 1-night trip
Posted 2 days ago
The Charlee Hotel

Find out more about Santa Cruz

Find out more about Santa Cruz

Search for holiday rentals in Santa Cruz on Expedia! You can easily find your home rentals, villas, holiday apartments in Santa Cruz using one of the methods below:

  • View our selection of featured holiday rentals in Santa Cruz
  • Use the map to find apartments and other holiday homes in the Santa Cruz neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Santa Cruz while they last

Look no further and take a look at our great range of rental properties in Santa Cruz!

Frequently asked questions

Can I find a holiday rental in Santa Cruz?

Yes, there are holiday rentals close to the most popular sights in Santa Cruz, or you can select a more secluded option if you're looking for a relaxing stay.

What are some of the best holiday rentals that Santa Cruz has to offer?

EP Casa Uribe Architecture Art & Nature: This holiday home rental outside of Santa Cruz is located in a shopping district, and has an outdoor pool, a balcony and laundry facilities to put you at ease in your new surroundings. Kitchen amenities include a dishwasher, a fridge and a stovetop.

What’s there to see and do in Santa Cruz?

While exploring the area, visit family-friendly sights like Pueblito Paisa, or get outside and enjoy nature at Medellin Botanical Garden. In the wider area, you’ll find University of Antioquia and Arvi Park.

What’s a holiday rental in Santa Cruz like?

Holiday rentals are private properties where you can stay for a few weeks, or just a few days, in Santa Cruz. Holiday rentals offer extras like WiFi and washers and dryers so you'll feel right at home. If you're concerned about a clean environment, holiday rentals can offer a sense of safety away from public hotel lifts and lobbies bustling with people while still allowing you the enjoyment of travel. You'll also find more space in a holiday rental than in a standard hotel, which is another reason why a holiday rental is a popular option for families.