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Check prices for these dates

In two weeks
1 May - 3 May
In two months
12 Jun - 14 Jun
In three months
10 Jul - 12 Jul
In four months
7 Aug - 9 Aug

Our top choices for Santa Cruz holiday rentals

Interior

Casagrande

Casagrande
2.0 star property
Rionegro
10.0 out of 10, Exceptional, (1 review)
"Very nice large room with king size bed, very low noise beautiful Mountain View’s. It was a little cold for pool but, various shopping centers close to property and public transport passes right in front. Awesome place to stay."
United States
Alex
The price is ฿1,763
฿1,763 total
14 Apr - 15 Apr
Casagrande
Deluxe Apartment, Garden View | Desk, laptop workspace, blackout curtains, soundproofing

Edificio Cielo Verde

Edificio Cielo Verde
3.0 star property
Rionegro
The price is ฿4,583
฿5,465 total
14 Apr - 15 Apr
Edificio Cielo Verde
Exterior

Candelaria Campestre

Candelaria Campestre
2.0 star property
El Carmen de Viboral
The price is ฿3,085
฿3,878 total
14 Apr - 15 Apr
Candelaria Campestre
Deluxe Apartment, 1 Queen Bed with Sofa bed, Non Smoking, Kitchen | 1 bedroom, premium bedding, down duvets, in-room safe

Portal del Rodeo ApartaHotel - Arkadia Mall

Portal del Rodeo ApartaHotel - Arkadia Mall
3.5 star property
Medellín
9.2 out of 10, Wonderful, (271 reviews)
"the staff was very friendly good food and the room is so nice highly recomended"
United States
Astrid
The price is ฿2,075
฿2,075 total
17 Apr - 18 Apr
Portal del Rodeo ApartaHotel - Arkadia Mall
Studio | View from room

Travelers Rio Verde Living Suites

Travelers Rio Verde Living Suites
3.5 star property
Rionegro
8.4 out of 10, Very good, (473 reviews)
"GOOD PLACE TO STAY THE NIGHT NEAR THE AIRPORT"
United States
Robert
The price is ฿2,427
฿2,427 total
14 Apr - 15 Apr
Travelers Rio Verde Living Suites
Suite (302) | Minibar, desk, laptop workspace, blackout curtains

Mali Experience

Mali Experience
3.0 star property
Rionegro
10.0 out of 10, Exceptional, (2 reviews)
"My room was a well-equipped luxury studio apartment that included a washer/dryer (what a treat) and a great small kitchen and a large walk-in shower. Absolutely loved my accommodation. And for you gringos and gringas out there with shaky Spanish, your host, Juan, not only speaks impeccable English but is so very helpful. Highly recommend!"
United States
Gabrielle
The price is ฿2,399
฿2,399 total
14 Apr - 15 Apr
Mali Experience
Living area

Skyline Ecoliving

Skyline Ecoliving
3.0 star property
El Rosario
9.2 out of 10, Wonderful, (42 reviews)
"Super impressive mountain view directly visible as soon as you open your eyes in the morning. "
United States
Antranik
The price is ฿2,135
฿2,556 total
20 Apr - 21 Apr
Skyline Ecoliving
1 bedroom, premium bedding, down duvets, free WiFi

Shabbat Hotel Boutique

Shabbat Hotel Boutique
4.0 star property
San Vicente
10.0 out of 10, Exceptional, (2 reviews)
"Excelente Servicio y facilidades. 100% recomendado"
United States
william
The price is ฿3,856
฿3,856 total
21 Apr - 22 Apr
Shabbat Hotel Boutique
Lobby

Haven, A Design Hotel

Haven, A Design Hotel
4.0 star property
El Poblado
8.8 out of 10, Excellent, (680 reviews)
"Was reallly good excellent locations"
United States
Alvaro
The price is ฿3,318
฿3,318 total
14 Apr - 15 Apr
Haven, A Design Hotel
Front of property

Hotel Rioverde- 5 minutos de cercanía al aeropuerto

Hotel Rioverde- 5 minutos de cercanía al aeropuerto
4.5 star property
Rionegro
7.4 out of 10, Good, (60 reviews)
"Clean room and good amenities. Close to the airport which was useful after a long flight "
Australia
DAVID
The price is ฿3,172
฿3,172 total
14 Apr - 15 Apr
Hotel Rioverde- 5 minutos de cercanía al aeropuerto
Standard Room, Patio, Mountain View | Outdoor dining

Almaia 17

Almaia 17
3.0 star property
Rionegro
The price is ฿1,666
฿3,957 total
14 Apr - 15 Apr
Almaia 17
Outdoor pool

PORTANOVA SUITES by ADVENTU

PORTANOVA SUITES by ADVENTU
3.0 star property
Rionegro
8.4 out of 10, Very good, (51 reviews)
"Room was very clean and apt is very quiet and close to the hospital "
United States
FERNANDO
The price is ฿1,456
฿1,985 total
14 Apr - 15 Apr
PORTANOVA SUITES by ADVENTU
Front of property

Seissta Medellin

Seissta Medellin
4.0 star property
El Poblado
9.4 out of 10, Exceptional, (236 reviews)
"Excellent modern facility"
United States
keith
The price is ฿3,462
฿3,462 total
12 May - 13 May
Seissta Medellin
Reception

Sites Hotel

Sites Hotel
4.0 star property
El Poblado
9.2 out of 10, Wonderful, (1,143 reviews)
"Everything was great, and the staff were so helpful and nice all the time, will definitely be back. "
United States
Romulo
The price is ฿2,418
฿2,418 total
20 Apr - 21 Apr
Sites Hotel
Villa | Pool | Outdoor pool

Luxury Villa In Provenza

Luxury Villa In Provenza
4.0 star property
El Poblado
The price is ฿29,482
฿32,686 total
14 Apr - 15 Apr
Luxury Villa In Provenza
Premium Cabin | Minibar, individually decorated, individually furnished, free WiFi

Wasikuna cabañas rurales tipo glamping

Wasikuna cabañas rurales tipo glamping
3.0 star property
Guarne
9.2 out of 10, Wonderful, (5 reviews)
"Nice place "
United States
GERARDO
The price is ฿5,112
฿5,112 total
14 Apr - 15 Apr
Wasikuna cabañas rurales tipo glamping
Deluxe Cabin, Balcony, Mountain View

Onirico Luxury

Onirico Luxury
2.0 star property
Medellin
The price is ฿2,776
฿2,776 total
14 Apr - 15 Apr
Onirico Luxury
Reception

Praia Apartaestudios

Praia Apartaestudios
4.5 star property
Sabaneta
8.0 out of 10, Very good, (15 reviews)
"It nice and comfortable. "
United States
DENIS
The price is ฿1,349
฿1,349 total
13 May - 14 May
Praia Apartaestudios
Deluxe Apartment | Living area | 43-inch Smart TV with satellite channels, TV

Alcázar de Oviedo By EE Hotels

Alcázar de Oviedo By EE Hotels
3.0 star property
El Poblado
9.4 out of 10, Exceptional, (169 reviews)
"Love it, been here for my second time and will choose it again"
United States
Annelies
The price is ฿3,269
฿3,269 total
19 Apr - 20 Apr
Alcázar de Oviedo By EE Hotels
Room

hotel civitas medellin

hotel civitas medellin
2.5 star property
La Candelaria
10.0 out of 10, Exceptional, (1 review)
"Hotel in a good location, comfortable and has a great staff."
United States
Valencia
The price is ฿808
฿808 total
14 Apr - 15 Apr
hotel civitas medellin
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

Hashtag 98 Hotel By Jalo

Hashtag 98 Hotel By Jalo

2/10 Terrible
"Long list of issues won't be back"
Alexander 7-night trip
Posted 4 hours ago
Hashtag 98 Hotel By Jalo

Find out more about Santa Cruz

Search for holiday rentals in Santa Cruz on Expedia! You can easily find your home rentals, villas, holiday apartments in Santa Cruz using one of the methods below:

  • View our selection of featured holiday rentals in Santa Cruz
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  • Enter your travel dates to view the best deals on holiday rentals in Santa Cruz while they last

Look no further and take a look at our great range of rental properties in Santa Cruz!

Frequently asked questions

Can I find a holiday rental in Santa Cruz?

Yes, there are holiday rentals close to the most popular sights in Santa Cruz, or you can select a more secluded option if you're looking for a relaxing stay.

What’s there to see and do in Santa Cruz?

While exploring the area, visit family-friendly sights like Pueblito Paisa, or get outside and enjoy nature at Medellin Botanical Garden. In the wider area, you’ll find University of Antioquia and Arvi Park.

What’s a holiday rental in Santa Cruz like?

Holiday rentals are private properties where you can stay for a few weeks, or just a few days, in Santa Cruz. Holiday rentals offer extras like WiFi and washers and dryers so you'll feel right at home. If you're concerned about a clean environment, holiday rentals can offer a sense of safety away from public hotel lifts and lobbies bustling with people while still allowing you the enjoyment of travel. You'll also find more space in a holiday rental than in a standard hotel, which is another reason why a holiday rental is a popular option for families.